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Volumn 46, Issue 2, 2011, Pages 488-496

Structure-based design, synthesis and preliminary anti-inflammatory activity of bolinaquinone analogues

(11) Petronzi, Carmen a Filosa, Rosanna a Peduto, Antonella a Monti, Maria Chiara a Margarucci, Luigi a Massa, Antonio a Ercolino, Simona Francesca a Bizzarro, Valentina a Parente, Luca a Riccio, Raffaele a De Caprariis, Paolo a

a UNIVERSITY OF SALERNO (Italy)

Author keywords

anti Inflammatory drugs; Bolinaquinone analogues; hsPLA2

Indexed keywords

5 (2 DIBENZOFURANYL) 2 HYDROXY 2,5 CYCLOHEXADIENE 1,4 DIONE; 5 (2 NAPHTHYL) 2 HYDROXY 2,5 CYCLOHEXADIENE 1,4 DIONE; 5 (2 NAPHTHYLAMINO) 2 HYDROXY 2,5 CYCLOHEXADIENE 1,4 DIONE; 5 (2 NAPHTHYLOXY) 2 HYDROXY 2,5 CYCLOHEXADIENE 1,4 DIONE; 5 (2 THIANTHRENYL) 2 HYDROXY 2,5 CYCLOHEXADIENE 1,4 DIONE; 5 (3 NITROPHENYL) 2 HYDROXY 2,5 CYCLOHEXADIENE 1,4 DIONE; 5 (4 CHLOROPHENYL) 2 HYDROXY 2,5 CYCLOHEXADIENE 1,4 DIONE; 5 (4 HYDROXYPHENYL) 2 HYDROXY 2,5 CYCLOHEXADIENE 1,4 DIONE; 5 [(1,10 BIPHENYL) 4 YL] 2 HYDROXY 2,5 CYCLOHEXADIENE 1,4 DIONE; 5 [(2 NAPHTHYL)METHYL] 2 HYDROXY 2,5 CYCLOHEXADIENE 1,4 DIONE; 5 [4 (1,10 BIPHENYL)] 2 HYDROXY 2,5 CYCLOHEXADIENE 1,4 DIONE; 5 BENZYL 2 HYDROXY 2,5 CYCLOHEXADIENE 1,4 DIONE; 5 HEXYL 2 HYDROXY 2,5 CYCLOHEXADIENE 1,4 DIONE; ANTIINFLAMMATORY AGENT; BOLINAQUINONE; PROSTAGLANDIN E2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BINDING AFFINITY; CELL LINE; DRUG DETERMINATION; DRUG POTENCY; DRUG SYNTHESIS; MACROPHAGE; MOUSE; NONHUMAN; STRUCTURE ACTIVITY RELATION; SURFACE PLASMON RESONANCE;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELL LINE; CYCLOOXYGENASE 2; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; HUMANS; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MOLECULAR STRUCTURE; SESQUITERPENES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; SURFACE PLASMON RESONANCE;

EID: 79151486488 PISSN: 02235234 EISSN: 17683254 Source Type: Journal
DOI: 10.1016/j.ejmech.2010.11.028 Document Type: Article

Times cited : (32)

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