Nickel-catalyzed cross-coupling of non-activated and functionalized alkyl halides with alkyl grignard reagents

Angewandte Chemie - International Edition

Volumn 48, Issue 16, 2009, Pages 2937-2940

  Vechorkin, Oleg ^a   Hu, Xile ^a  

^a EPFL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYL HALIDES; CROSS COUPLING REACTIONS; CROSS-COUPLINGS; FUNCTIONALIZED; GRIGNARD REAGENT;

FUNCTIONAL GROUPS;

ALKYLATION;

EID: 70349778999     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200806138     Document Type: Article

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21. Similar results are obtained when the reactions are conducted at -35 °C for 30 min or when the reagents are mixed at -35 °C and then the reaction mixtures are warmed up over a 30 min time period.
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