Nickel-catalyzed cross-coupling of potassium aryl- and heteroaryltrifluoroborates with unactivated alkyl halides

Organic Letters

Volumn 12, Issue 24, 2010, Pages 5783-5785

  Molander, Gary A ^a   Argintaru, O Andreea ^a   Aron, Ioana ^a   Dreher, Spencer D ^b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORINE DERIVATIVE; HALOGEN; NICKEL; POTASSIUM;

ALKYLATION; ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY;

ALKYLATION; CATALYSIS; FLUORINE COMPOUNDS; HALOGENS; MOLECULAR STRUCTURE; NICKEL; POTASSIUM;

EID: 78650410560     PISSN: 15237060     EISSN: 15237052     Source Type: Journal    
DOI: 10.1021/ol102717x     Document Type: Article

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26. Under these conditions, reactions of other heteroaryltrifluoroborates (furans, thiophenes, pyrazoles) proceeded in relatively low yield (<40%, data not shown). The cross-coupling of alkyl chlorides with aryl- and heteroaryltrifluoroborates is currently under study.