Pdx1 is post-translationally modified in vivo and serine 61 is the principal site of phosphorylation

PLoS ONE

Volumn 7, Issue 4, 2012, Pages

  Frogne, Thomas ^a   Sylvestersen, Kathrine Beck ^b   Kubicek, Stefan ^c   Nielsen, Michael Lund ^b   Hecksher Sørensen, Jacob ^a  

^a HAGEDORN RESEARCH INSTITUTE   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c ERICH SCHMID INSTITUTE OF MATERIALS SCIENCE   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; ANTIBODY; INSULIN; PROTEIN; SERINE; SERINE 61; TRANSCRIPTION FACTOR PDX 1; UNCLASSIFIED DRUG; HOMEODOMAIN PROTEIN; NKX6 1 PROTEIN, MOUSE; NKX6-1 PROTEIN, MOUSE; PANCREATIC AND DUODENAL HOMEOBOX 1 PROTEIN; TRANSACTIVATOR PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL FUNCTION; CELL STRAIN HEK293; CELLULAR DISTRIBUTION; DIABETES MELLITUS; EMBRYO; EMBRYO DEVELOPMENT; EUKARYOTIC CELL; GLUCOSE HOMEOSTASIS; HAPLOINSUFFICIENCY; HUMAN; IMMUNOASSAY; IMPAIRED GLUCOSE TOLERANCE; IN VIVO STUDY; ISOELECTRIC FOCUSING; MASS SPECTROMETRY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; ORGANOGENESIS; PANCREAS DEVELOPMENT; PANCREAS ISLET BETA CELL; PHOSPHORYLATION SITE; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; SIGNAL TRANSDUCTION; TISSUE CULTURE; ANIMAL; CHICKEN; GENE EXPRESSION REGULATION; GENETICS; GLUCOSE BLOOD LEVEL; GLUCOSE INTOLERANCE; GROWTH, DEVELOPMENT AND AGING; METABOLISM; PHOSPHORYLATION;

EUKARYOTA; MUS;

ANIMALS; BLOOD GLUCOSE; CHICKENS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLUCOSE INTOLERANCE; HEK293 CELLS; HOMEODOMAIN PROTEINS; HUMANS; INSULIN; INSULIN-SECRETING CELLS; MICE; PHOSPHORYLATION; SERINE; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS;

EID: 84859589878     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0035233     Document Type: Article

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