Microtubular stability affects pVHL-mediated regulation of HIF-1alpha via the p38/MAPK pathway in hypoxic cardiomyocytes

PLoS ONE

Volumn 7, Issue 4, 2012, Pages

  Teng, Miao ^a   Jiang, Xu pin ^a   Zhang, Qiong ^a   Zhang, Jia ping ^a   Zhang, Dong xia ^a   Liang, Guang ping ^a   Huang, Yue sheng ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ADENOVIRUS VECTOR; COLCHICINE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MICROTUBULE ASSOCIATED PROTEIN 4; MITOGEN ACTIVATED PROTEIN KINASE KINASE 6; MITOGEN ACTIVATED PROTEIN KINASE P38; PACLITAXEL; SMALL INTERFERING RNA; VON HIPPEL LINDAU PROTEIN; HIF1A PROTEIN, RAT; MAP4; MICROTUBULE ASSOCIATED PROTEIN; TUBULIN; UBIQUITIN PROTEIN LIGASE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL HYPOXIA; CONTROLLED STUDY; DEPOLYMERIZATION; DOWN REGULATION; GENE ACTIVATION; GENE CONSTRUCT; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE OVEREXPRESSION; GENE SILENCING; GENETIC STABILITY; GENETIC TRANSFECTION; HEART MUSCLE CELL; MICROTUBULE ASSEMBLY; NEWBORN; NONHUMAN; PLASMID; RAT; UPREGULATION; ANIMAL; CELL CULTURE; GENETICS; METABOLISM; MICROTUBULE; PHOSPHORYLATION; PHYSIOLOGY; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ADENOVIRIDAE; RATTUS;

ANIMALS; CELL HYPOXIA; CELLS, CULTURED; DOWN-REGULATION; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MICROTUBULE-ASSOCIATED PROTEINS; MICROTUBULES; MYOCYTES, CARDIAC; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TUBULIN; UBIQUITIN-PROTEIN LIGASES; UP-REGULATION; VON HIPPEL-LINDAU TUMOR SUPPRESSOR PROTEIN;

EID: 84859571487     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0035017     Document Type: Article

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