-
1
-
-
0028884033
-
PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase in vitro and in vivo
-
Alessi D.R., Cuenda A., Cohen P., Dudley D.T., and Saltiel A.R. PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase in vitro and in vivo. J. Biol. Chem. 270 (1995) 27489-27494
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 27489-27494
-
-
Alessi, D.R.1
Cuenda, A.2
Cohen, P.3
Dudley, D.T.4
Saltiel, A.R.5
-
2
-
-
0035923665
-
SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase
-
Bennett B.L., Sasaki D.T., Murray B.W., O'Leary E.C., Sakata S.T., Xu W., Leisten J.C., Motiwala A., Pierce S., Satoh Y., Bhagwat S.S., Manning A.M., and Anderson D.W. SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase. Proc. Natl. Acad. Sci. 98 (2001) 13681-13686
-
(2001)
Proc. Natl. Acad. Sci.
, vol.98
, pp. 13681-13686
-
-
Bennett, B.L.1
Sasaki, D.T.2
Murray, B.W.3
O'Leary, E.C.4
Sakata, S.T.5
Xu, W.6
Leisten, J.C.7
Motiwala, A.8
Pierce, S.9
Satoh, Y.10
Bhagwat, S.S.11
Manning, A.M.12
Anderson, D.W.13
-
5
-
-
0028988138
-
SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1
-
Cuenda A., Rouse J., Doza Y.N., Meier R., Cohen P., Gallagher T.F., Young P.R., and Lee J.C. SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1. FEBS Lett. 364 (1995) 229-233
-
(1995)
FEBS Lett.
, vol.364
, pp. 229-233
-
-
Cuenda, A.1
Rouse, J.2
Doza, Y.N.3
Meier, R.4
Cohen, P.5
Gallagher, T.F.6
Young, P.R.7
Lee, J.C.8
-
6
-
-
0019256571
-
Reduced somatostatin-like immunoreactivity in cerebral cortex from cases of Alzheimer disease and Alzheimer senile dementa
-
Davies P., Katzman R., and Terry R.D. Reduced somatostatin-like immunoreactivity in cerebral cortex from cases of Alzheimer disease and Alzheimer senile dementa. Nature 288 (1980) 279-280
-
(1980)
Nature
, vol.288
, pp. 279-280
-
-
Davies, P.1
Katzman, R.2
Terry, R.D.3
-
7
-
-
24944536068
-
A new tool in the battle against Alzheimer's disease and aging: ex vivo gene therapy
-
Ebert A.D., and Svendsen C.N. A new tool in the battle against Alzheimer's disease and aging: ex vivo gene therapy. Rejuvenation Res. 8 (2005) 131-134
-
(2005)
Rejuvenation Res.
, vol.8
, pp. 131-134
-
-
Ebert, A.D.1
Svendsen, C.N.2
-
8
-
-
20444426695
-
Apoptosis: a key in neurodegenerative disorders
-
Ekshyyan O., and Aw T.Y. Apoptosis: a key in neurodegenerative disorders. Curr. Neurovasc. Res. 1 (2004) 355-371
-
(2004)
Curr. Neurovasc. Res.
, vol.1
, pp. 355-371
-
-
Ekshyyan, O.1
Aw, T.Y.2
-
9
-
-
14444279192
-
Identification of a novel inhibitor of mitogen-activated protein kinase
-
Favata M.F., Horiuchi K.Y., Manos E.J., Daulerio A.J., Stradley D.A., Feeser W.S., Van Dyk D.E., Pitts W.J., Earl R.A., Hobbs F., Copeland R.A., Magolda R.L., Scherle P.A., and Trzaskos J.M. Identification of a novel inhibitor of mitogen-activated protein kinase. J. Biol. Chem. 273 (1998) 18623-18632
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 18623-18632
-
-
Favata, M.F.1
Horiuchi, K.Y.2
Manos, E.J.3
Daulerio, A.J.4
Stradley, D.A.5
Feeser, W.S.6
Van Dyk, D.E.7
Pitts, W.J.8
Earl, R.A.9
Hobbs, F.10
Copeland, R.A.11
Magolda, R.L.12
Scherle, P.A.13
Trzaskos, J.M.14
-
10
-
-
0036836070
-
Translocation of apoptosis-inducing factor in cerebellar granule cells exposed to neurotoxic agents inducing oxidative stress
-
Fonfria E., Dare E., Benelli M., Sunol C., and Ceccatelli S. Translocation of apoptosis-inducing factor in cerebellar granule cells exposed to neurotoxic agents inducing oxidative stress. Eur. J. Neurosci. 16 (2002) 2013-2016
-
(2002)
Eur. J. Neurosci.
, vol.16
, pp. 2013-2016
-
-
Fonfria, E.1
Dare, E.2
Benelli, M.3
Sunol, C.4
Ceccatelli, S.5
-
11
-
-
0028984353
-
Taxol stabilizes [Ca2+]i and protects hippocampal neurons against excitotoxicity
-
Furukawa K., and Mattson M.P. Taxol stabilizes [Ca2+]i and protects hippocampal neurons against excitotoxicity. Brain Res. 689 (1995) 141-146
-
(1995)
Brain Res.
, vol.689
, pp. 141-146
-
-
Furukawa, K.1
Mattson, M.P.2
-
12
-
-
0033006449
-
Cytochrome c release and caspase-3 activation during colchicine-induced apoptosis of cerebellar granule cells
-
Gorman A.M., Bonfoco E., Zhivotovsky B., Orrenius S., and Ceccatelli S. Cytochrome c release and caspase-3 activation during colchicine-induced apoptosis of cerebellar granule cells. Eur. J. Neurosci. 11 (1999) 1067-1072
-
(1999)
Eur. J. Neurosci.
, vol.11
, pp. 1067-1072
-
-
Gorman, A.M.1
Bonfoco, E.2
Zhivotovsky, B.3
Orrenius, S.4
Ceccatelli, S.5
-
13
-
-
0043073209
-
Neuroprotective action of flavopiridol, a cyclin-dependent kinase inhibitor, in colchicine-induced apoptosis
-
Jorda E.G., Verdaguer E., Canudas A.M., Jimenez A., Bruna A., Caelles C., Bravo R., Escubedo E., Pubill D., Camarasa J., Pallas M., and Camins A. Neuroprotective action of flavopiridol, a cyclin-dependent kinase inhibitor, in colchicine-induced apoptosis. Neuropharmacology 45 (2003) 672-683
-
(2003)
Neuropharmacology
, vol.45
, pp. 672-683
-
-
Jorda, E.G.1
Verdaguer, E.2
Canudas, A.M.3
Jimenez, A.4
Bruna, A.5
Caelles, C.6
Bravo, R.7
Escubedo, E.8
Pubill, D.9
Camarasa, J.10
Pallas, M.11
Camins, A.12
-
14
-
-
12844282302
-
(+/-)-huprine Y, (-)-huperzine A and tacrine do not show neuroprotective properties in an apoptotic model of neuronal cytoskeletal alteration
-
Jorda E.G., Verdaguer E., Jimenez A., Canudas A.M., Rimbau V., Camps P., Munoz-Torrero D., Camins A., and Pallas M. (+/-)-huprine Y, (-)-huperzine A and tacrine do not show neuroprotective properties in an apoptotic model of neuronal cytoskeletal alteration. J. Alzheimer's Dis. 6 (2004) 577-583
-
(2004)
J. Alzheimer's Dis.
, vol.6
, pp. 577-583
-
-
Jorda, E.G.1
Verdaguer, E.2
Jimenez, A.3
Canudas, A.M.4
Rimbau, V.5
Camps, P.6
Munoz-Torrero, D.7
Camins, A.8
Pallas, M.9
-
15
-
-
0032006059
-
Microtubules and actin filaments: dynamic targets for cancer chemotherapy
-
Jordan M.A., and Wilson L. Microtubules and actin filaments: dynamic targets for cancer chemotherapy. Curr. Opin. Cell Biol. 10 (1998) 123-130
-
(1998)
Curr. Opin. Cell Biol.
, vol.10
, pp. 123-130
-
-
Jordan, M.A.1
Wilson, L.2
-
16
-
-
0017844137
-
Tetanus toxin: a cell surface marker for neurones in culture
-
Mirsky R., Wendon L.M., Black P., Stolkin C., and Bray D. Tetanus toxin: a cell surface marker for neurones in culture. Brain Res. 148 (1978) 251-259
-
(1978)
Brain Res.
, vol.148
, pp. 251-259
-
-
Mirsky, R.1
Wendon, L.M.2
Black, P.3
Stolkin, C.4
Bray, D.5
-
17
-
-
33645101470
-
A role for mixed lineage kinases in granule cell apoptosis induced by cytoskeletal disruption
-
Muller G.J., Geist M.A., Veng L.M., Willesen M.G., Johansen F.F., Leist M., and Vaudano E. A role for mixed lineage kinases in granule cell apoptosis induced by cytoskeletal disruption. J. Neurochem. 96 (2006) 1242-1252
-
(2006)
J. Neurochem.
, vol.96
, pp. 1242-1252
-
-
Muller, G.J.1
Geist, M.A.2
Veng, L.M.3
Willesen, M.G.4
Johansen, F.F.5
Leist, M.6
Vaudano, E.7
-
18
-
-
18244379883
-
Mixed lineage kinase activity of indolocarbazole analogues
-
Murakata C., Kaneko M., Gessner G., Angeles T.S., Ator M.A., O'Kane T.M., McKenna B.A., Thomas B.A., Mathiasen J.R., Saporito M.S., Bozyczko-Coyne D., and Hudkins R.L. Mixed lineage kinase activity of indolocarbazole analogues. Bioorg. Med. Chem. Lett. 12 (2002) 147-150
-
(2002)
Bioorg. Med. Chem. Lett.
, vol.12
, pp. 147-150
-
-
Murakata, C.1
Kaneko, M.2
Gessner, G.3
Angeles, T.S.4
Ator, M.A.5
O'Kane, T.M.6
McKenna, B.A.7
Thomas, B.A.8
Mathiasen, J.R.9
Saporito, M.S.10
Bozyczko-Coyne, D.11
Hudkins, R.L.12
-
19
-
-
0026058318
-
Cell death during development of the nervous system
-
Oppenheim R.W. Cell death during development of the nervous system. Annu. Rev. Neurosci. 14 (1991) 453-501
-
(1991)
Annu. Rev. Neurosci.
, vol.14
, pp. 453-501
-
-
Oppenheim, R.W.1
-
20
-
-
0027373764
-
Programmed cell death and the control of cell survival: lessons from the nervous system
-
Raff M.C., Barres B.A., Burne J.F., Coles H.S., Ishizaki Y., and Jacobson M.D. Programmed cell death and the control of cell survival: lessons from the nervous system. Science 262 (1993) 695-700
-
(1993)
Science
, vol.262
, pp. 695-700
-
-
Raff, M.C.1
Barres, B.A.2
Burne, J.F.3
Coles, H.S.4
Ishizaki, Y.5
Jacobson, M.D.6
-
21
-
-
0029011218
-
The MAPK signaling cascade
-
Seger R., and Krebs E.G. The MAPK signaling cascade. FASEB J. 9 (1995) 726-735
-
(1995)
FASEB J.
, vol.9
, pp. 726-735
-
-
Seger, R.1
Krebs, E.G.2
-
22
-
-
0035283128
-
Calcium ionophore A23187 specifically decreases the secretion of beta-secretase cleaved amyloid precursor protein during apoptosis in primary rat cortical cultures
-
Sennvik K., Benedikz E., Fastbom J., Sundstrom E., Winblad B., and Ankarcrona M. Calcium ionophore A23187 specifically decreases the secretion of beta-secretase cleaved amyloid precursor protein during apoptosis in primary rat cortical cultures. J. Neurosci. Res. 63 (2001) 429-437
-
(2001)
J. Neurosci. Res.
, vol.63
, pp. 429-437
-
-
Sennvik, K.1
Benedikz, E.2
Fastbom, J.3
Sundstrom, E.4
Winblad, B.5
Ankarcrona, M.6
-
23
-
-
0038374164
-
Cross-talk between JNK/SAPK and ERK/MAPK pathways: sustained activation of JNK blocks ERK activation by mitogenic factors
-
Shen Y.H., Godlewski J., Zhu J., Sathyanarayana P., Leaner V., Birrer M.J., Rana A., and Tzivion G. Cross-talk between JNK/SAPK and ERK/MAPK pathways: sustained activation of JNK blocks ERK activation by mitogenic factors. J. Biol. Chem. 18 (2003) 26715-26721
-
(2003)
J. Biol. Chem.
, vol.18
, pp. 26715-26721
-
-
Shen, Y.H.1
Godlewski, J.2
Zhu, J.3
Sathyanarayana, P.4
Leaner, V.5
Birrer, M.J.6
Rana, A.7
Tzivion, G.8
-
24
-
-
0034018813
-
Apoptosis in Alzheimer's disease-an update
-
Shimohama S. Apoptosis in Alzheimer's disease-an update. Apoptosis 5 (2000) 9-16
-
(2000)
Apoptosis
, vol.5
, pp. 9-16
-
-
Shimohama, S.1
-
25
-
-
0026558326
-
Mechanism of inhibition of microtubule polymerization by colchicine: inhibitory potencies of unliganded colchicine and tubulin-colchicine complexes
-
Skoufias D.A., and Wilson L. Mechanism of inhibition of microtubule polymerization by colchicine: inhibitory potencies of unliganded colchicine and tubulin-colchicine complexes. Biochemistry 28 (1992) 738-746
-
(1992)
Biochemistry
, vol.28
, pp. 738-746
-
-
Skoufias, D.A.1
Wilson, L.2
-
27
-
-
0034627879
-
Microtubule inhibitors elicit differential effects on MAP kinase (JNK, ERK, and p38) signaling pathways in human KB-3 carcinoma cells
-
Stone A.A., and Chambers T.C. Microtubule inhibitors elicit differential effects on MAP kinase (JNK, ERK, and p38) signaling pathways in human KB-3 carcinoma cells. Exp. Cell Res. 254 (2000) 110-119
-
(2000)
Exp. Cell Res.
, vol.254
, pp. 110-119
-
-
Stone, A.A.1
Chambers, T.C.2
-
28
-
-
0034685876
-
Microtubule-interfering agents stimulate the transcription of cyclooxygenase-2. Evidence for involvement of ERK1/2 AND p38 mitogen-activated protein kinase pathways
-
Subbaramaiah K., Hart J.C., Norton L., and Dannenberg A.J. Microtubule-interfering agents stimulate the transcription of cyclooxygenase-2. Evidence for involvement of ERK1/2 AND p38 mitogen-activated protein kinase pathways. J. Biol. Chem. 275 (2000) 14838-14845
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 14838-14845
-
-
Subbaramaiah, K.1
Hart, J.C.2
Norton, L.3
Dannenberg, A.J.4
-
29
-
-
0028943734
-
Apoptosis in the pathogenesis and treatment of disease
-
Thompson C.B. Apoptosis in the pathogenesis and treatment of disease. Science 267 (1995) 1456-1462
-
(1995)
Science
, vol.267
, pp. 1456-1462
-
-
Thompson, C.B.1
-
30
-
-
18544406054
-
SB 239063, a potent p38 MAP kinase inhibitor, reduces inflammatory cytokine production, airways eosinophil infiltration, and persistence
-
Underwood D.C., Osborn R.R., Kotzer C.J., Adams J.L., Lee J.C., Webb E.F., Carpenter D.C., Bochnowicz S., Thomas H.C., Hay D.W., and Griswold D.E. SB 239063, a potent p38 MAP kinase inhibitor, reduces inflammatory cytokine production, airways eosinophil infiltration, and persistence. J. Pharmacol. Exp. Ther. 293 (2000) 281-288
-
(2000)
J. Pharmacol. Exp. Ther.
, vol.293
, pp. 281-288
-
-
Underwood, D.C.1
Osborn, R.R.2
Kotzer, C.J.3
Adams, J.L.4
Lee, J.C.5
Webb, E.F.6
Carpenter, D.C.7
Bochnowicz, S.8
Thomas, H.C.9
Hay, D.W.10
Griswold, D.E.11
-
32
-
-
0028880006
-
Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
-
Xia Z., Dickens M., Raingeaud J., Davis R.J., and Greenberg M.E. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 24 (1995) 1326-1331
-
(1995)
Science
, vol.24
, pp. 1326-1331
-
-
Xia, Z.1
Dickens, M.2
Raingeaud, J.3
Davis, R.J.4
Greenberg, M.E.5
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