Taxol, a microtubule stabilizer, prevents ischemic ventricular arrhythmias in rats

Journal of Cellular and Molecular Medicine

Volumn 15, Issue 5, 2011, Pages 1166-1176

  Xiao, Junjie ^a,b   Cao, Huaming ^a,b   Liang, Dandan ^a,b,c   Liu, Ying ^a,b   Zhang, Hong ^a,b   Zhao, Hong ^a,b   Liu, Yi ^a,b,c   Li, Jun ^a,b,c   Yan, Biao ^a,b,c   Peng, Luying ^a,b,c   Zhou, Zhaonian ^d   Chen, Yi Han ^a,b,c  

^a BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^b TONGJI UNIVERSITY SCHOOL OF MEDICINE   (China)

^c TONGJI UNIVERSITY   (China)

^d Shanghai Jiao Tong University Affiliated Sixth People s Hospital   (China)

Author keywords

Calcium overload; Ischemic ventricular arrhythmias; Microtubule; Reactive oxygen species; Taxol

Indexed keywords

CALCIUM; MULTIENZYME COMPLEX; PACLITAXEL; REACTIVE OXYGEN METABOLITE; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; TUBULIN MODULATOR;

ANIMAL; ARTICLE; HEART ARRHYTHMIA; HEART INFARCTION; METABOLISM; RAT; SPRAGUE DAWLEY RAT;

ANIMALS; ARRHYTHMIAS, CARDIAC; CALCIUM; ELECTRON TRANSPORT CHAIN COMPLEX PROTEINS; MYOCARDIAL INFARCTION; PACLITAXEL; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; TUBULIN MODULATORS;

RATTUS;

EID: 79957621099     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1582-4934.2010.01106.x     Document Type: Article

References (35)

1. 2+ ATPase pump overexpression in a porcine model of ischemia reperfusion. Circulation. 2008; 118: 614-24.
2. Farkas A, Qureshi, Curtis MJ. Inadequate ischaemia-selectivity limits the antiarrhythmic efficacy of mibefradil during regional ischaemia and reperfusion in the rat isolated perfused heart. Br J Pharmacol. 1999; 128: 41-50.
3. Members of the Sicilian G. New approaches to antiarrhythmic therapy: emerging therapeutic applications of the cell biology of cardiac arrhythmias. Circulation. 2001; 104: 345-60.
4. Hall MCS, Todd DM. Modern management of arrhythmias. Postgrad Med J. 2006; 82: 117-25.
5. 2+ signaling in rat cardiac myocytes. Circ Res. 2000; 86: 30-6.
6. Bloom K. Microtubule composition: cryptography of dynamic polymers. Proc Natl Acad Sci USA. 2004; 101: 6839-40.
7. Gerdes JM, Katsanis N. Small molecule intervention in microtubule-associated human disease. Hum Mol Genet. 2005; 14: R291-300.
8. Unno T, Komori S, Ohashi H. Microtubule cytoskeleton involvement in muscarinic suppression of voltage-gated calcium channel current in guinea-pig ileal smooth muscle. Br J Pharmacol. 1999; 127: 1703-11.
9. Nakamura Y, Miura T, Nakano A, et al Role of microtubules in ischemic preconditioning against myocardial infarction. Cardiovasc Res. 2004; 64: 322-30.
10. Ismaeil MS, Tkachenko I, Hickey RF, et al Colchicine inhibits isoflurane-induced preconditioning. Anesthesiology. 1999; 91: 1816-22.
11. Lampidis TJ, Kolonias D, Savaraj N, et al Cardiostimulatory and antiarrhythmic activity of tubulin-binding agents. Proc Natl Acad Sci USA. 1992; 89: 1256-60.
12. Parker KK, Taylor LK, Atkinson JB, et al The effects of tubulin-binding agents on stretch-induced ventricular arrhythmias. Eur J Pharmacol. 2001; 417: 131-40.
13. Wyse DG, Friedman PL, Brodsky MA, et al Life-threatening ventricular arrhythmias due to transient or correctable causes: high risk for death in follow-up. J Am Coll Cardiol. 2001; 36: 1718-24.
14. de Diego C, Pai RK, Chen F, et al Electrophysiological consequences of acute regional ischemia/reperfusion in neonatal rat ventricular myocyte monolayers. Circulation. 2008; 118: 2330-7.
15. Ganote C, Armstrong S. Ischaemia and the myocyte cytoskeleton: review and speculation. Cardiovasc Res. 1993; 27: 1387-403.
16. Thandroyen FT, McCarthy J, Burton KP, et al Ryanodine and caffeine prevent ventricular arrhythmias during acute myocardial ischemia and reperfusion in rat heart. Circ Res. 1988; 62: 306-14.
17. Yang CS, Tsai PJ, Chou ST, et al The roles of reactive oxygen species and endogenous opioid peptides in ischemia-induced arrhythmia of isolated rat hearts. Free Radic Biol Med. 1995; 18: 593-8.
18. Walker MJA, Curtis MJ, Hearse DJ, et al The Lambeth Conventions: guidelines for the study of arrhythmias in ischaemia, infarction, and reperfusion. Cardiovasc Res. 1988; 22: 447-55.
19. Sato H, Hori M, Kitakaze M, et al Reperfusion after brief ischemia disrupts the microtubule network in canine hearts. Circ Res. 1993; 72: 361-75.
20. Cao CM, Xia Q, Gao Q, et al Calcium-activated potassium channel triggers cardioprotection of ischemic preconditioning. J Pharmacol Exp Ther. 2005; 312: 644-50.
21. Li J, Xiao J, Liu Y, et al Mitochondrial benzodiazepine receptors mediate cardioprotection of estrogen against ischemic ventricular fibrillation. Pharmacol Res. 2009; 60: 61-7.
22. Miyamoto MI, del Monte F, Schmidt U, et al Adenoviral gene transfer of SERCA2a improves left-ventricular function in aortic-banded rats in transition to heart failure. Proc Natl Acad Sci USA. 2000; 18: 793-8.
23. 2+ current in rat ventricular myocytes. J Physiol. 1999; 516: 409-19.
24. Kerfant BG, Vassort G, Gomez AM. Microtubule disruption by colchicine reversibly enhances calcium signaling in intact rat cardiac myocytes. Circ Res. 2001; 88: E59-65.
25. Skobel E, Kammermeier H. Relation between enzyme release and irreversible cell injury of the heart under the influence of cytoskeleton modulating agents. Biochim Biophys Acta. 1997; 1362: 128-34.
26. Lee CF, Liu CY, Hsieh RH, et al Oxidative stress-induced depolymerization of microtubules and alteration of mitochondrial mass in human cells. Ann NY Acad Sci. 2005; 1042: 246-54.
27. Petrosillo G, Ruggiero FM, Di Venosa N, et al Decreased complex III activity in mitochondria isolated from rat heart subjected to ischemia and reperfusion: role of reactive oxygen species and cardiolipin. FASEB J. 2003; 17: 714-6.
28. Kevin LG, Novalija E, Stowe DF. Reactive oxygen species as mediators of cardiac injury and protection: the relevance to anesthesia practice. Anesth Analg. 2005; 101: 1275-87.
29. Shah M, Akar FG, Tomaselli GF. Molecular basis of arrhythmias. Circulation. 2005; 112: 2517-29.
30. Ter Keurs HE, Boyden PA. Calcium and arrhythmogenesis. Physiol Rev. 2007; 87: 457-506.
31. del Monte F, Lebeche D, Guerrero JL, et al Abrogation of ventricular arrhythmias in a model of ischemia and reperfusion by targeting myocardial calcium cycling. Proc Natl Acad Sci USA. 2004; 101: 5622-7.
32. Bers DM. Calcium and cardiac rhythms: physiological and pathophysiological. Circ Res. 2002; 90: 14-7.
33. Clusin WT. Mechanisms of calcium transient and action potential alternans in cardiac cells and tissues. Am J Physiol Heart Circ Physiol. 2008; 294: H1-10.
34. Morissette MR, Stricker JC, Rosenberg MA, et al Effects of myostatin deletion in aging mice. Aging Cell. 2009; 8: 573-83.
35. Paradies G, Petrosillo G, Pistolese M, et al Decrease in mitochondrial complex I activity in ischemic/reperfused rat heart: involvement of reactive oxygen species and cardiolipin. Circ Res. 2004; 94: 53-9.