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Volumn 92, Issue 4, 2011, Pages 321-335

Acetyl-coenzyme A carboxylase - an attractive enzyme for biotechnology

Author keywords

Acetyl coenzyme A carboxylase; Biotechnology; Fatty acid; Metabolic engineering

Indexed keywords


EID: 84859532678     PISSN: 08607796     EISSN: None     Source Type: Journal    
DOI: 10.5114/bta.2011.46549     Document Type: Review
Times cited : (13)

References (69)
  • 2
    • 0035970805 scopus 로고    scopus 로고
    • Continuous fatty acid oxidation and reduced fat storage in mice lacking acetyl-CoA carboxylase 2
    • Abu-Elheiga L., Matzuk M.M., Abo-Hashema K.A., Wakil S.J. (2001) Continuous fatty acid oxidation and reduced fat storage in mice lacking acetyl-CoA carboxylase 2. Science. 291: 2613-2616.
    • (2001) Science , vol.291 , pp. 2613-2616
    • Abu-Elheiga, L.1    Matzuk, M.M.2    Abo-Hashema, K.A.3    Wakil, S.J.4
  • 3
    • 0042337449 scopus 로고    scopus 로고
    • Acetyl-CoA carboxylase 2 mutant mice are protected against obesity and diabetes induced by high-fat/high-carbohydrate diets
    • Abu-Elheiga L., Oh W., Kordari P., Wakil S.J. (2003) Acetyl-CoA carboxylase 2 mutant mice are protected against obesity and diabetes induced by high-fat/high-carbohydrate diets. Proc. Natl. Acad. Sci. USA 100: 10207-10212.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 10207-10212
    • Abu-Elheiga, L.1    Oh, W.2    Kordari, P.3    Wakil, S.J.4
  • 4
    • 14644389417 scopus 로고    scopus 로고
    • Structure and regulation of acetyl-CoA carboxylase genes of metazoa
    • Barber M.C., Price N.T., Travers M.T. (2005) Structure and regulation of acetyl-CoA carboxylase genes of metazoa. Biochim. Biophys. Acta. 1733: 1-28.
    • (2005) Biochim. Biophys. Acta , vol.1733 , pp. 1-28
    • Barber, M.C.1    Price, N.T.2    Travers, M.T.3
  • 6
    • 23044482013 scopus 로고    scopus 로고
    • RNA interference-mediated silencing of the acetyl-CoAcarboxylase-alpha gene induces growth inhibition and apoptosis of prostate cancer cells
    • Brusselmans K., De S.E., Verhoeven G., Swinnen J.V. (2005) RNA interference-mediated silencing of the acetyl-CoAcarboxylase-alpha gene induces growth inhibition and apoptosis of prostate cancer cells. Cancer Res. 65: 6719-6725.
    • (2005) Cancer Res , vol.65 , pp. 6719-6725
    • Brusselmans, K.1    De, S.E.2    Verhoeven, G.3    Swinnen, J.V.4
  • 7
    • 80052611057 scopus 로고    scopus 로고
    • Improved phloroglucinol production by metabolically engineered Escherichia coli
    • Cao Y., Jiang X., Zhang R., Xian M. (2011) Improved phloroglucinol production by metabolically engineered Escherichia coli. Appl. Microbiol. Biotechnol. 91: 1545-1552.
    • (2011) Appl. Microbiol. Biotechnol , vol.91 , pp. 1545-1552
    • Cao, Y.1    Jiang, X.2    Zhang, R.3    Xian, M.4
  • 8
    • 66149149763 scopus 로고    scopus 로고
    • System analysis of an Arabidopsis mutant altered in de novo fatty acid synthesis reveals diverse changes in seed composition and metabolism
    • Chen M., Mooney B.P., Hajduch M., Joshi T., Zhou M., Xu D., Thelen J.J. (2009) System analysis of an Arabidopsis mutant altered in de novo fatty acid synthesis reveals diverse changes in seed composition and metabolism. Plant Physiol. 150: 27-41.
    • (2009) Plant Physiol , vol.150 , pp. 27-41
    • Chen, M.1    Mooney, B.P.2    Hajduch, M.3    Joshi, T.4    Zhou, M.5    Xu, D.6    Thelen, J.J.7
  • 10
    • 0028960890 scopus 로고
    • Defective export of a periplasmic enzyme disrupts regulation of fatty acid synthesis
    • Cho H., Cronan J.E., Jr (1995) Defective export of a periplasmic enzyme disrupts regulation of fatty acid synthesis. Biol. Chem. 270: 4216-4219.
    • (1995) Biol. Chem , vol.270 , pp. 4216-4219
    • Cho, H.1    Cronan Jr., J.E.2
  • 13
    • 0034666431 scopus 로고    scopus 로고
    • Overproduction of acetyl-CoA carboxylase activity increases the rate of fatty acid biosynthesis in Escherichia coli
    • Davis M.S., Solbiati J., Cronan J.E. Jr (2000) Overproduction of acetyl-CoA carboxylase activity increases the rate of fatty acid biosynthesis in Escherichia coli. Biol. Chem. 275: 28593-28598.
    • (2000) Biol. Chem , vol.275 , pp. 28593-28598
    • Davis, M.S.1    Solbiati, J.2    Cronan Jr., J.E.3
  • 14
    • 20444456337 scopus 로고    scopus 로고
    • Molecular bases for sensitivity to acetyl-coenzyme A carboxylase inhibitors in black-grass
    • Delye C., Zhang X.Q., Michel S., Matejicek A., Powles S.B. (2005) Molecular bases for sensitivity to acetyl-coenzyme A carboxylase inhibitors in black-grass. Plant Physiol. 137: 794-806.
    • (2005) Plant Physiol , vol.137 , pp. 794-806
    • Delye, C.1    Zhang, X.Q.2    Michel, S.3    Matejicek, A.4    Powles, S.B.5
  • 15
    • 0033728230 scopus 로고    scopus 로고
    • Altered target sites as a mechanism of herbicide resistance
    • Devine M.D., Shukla A. (2000) Altered target sites as a mechanism of herbicide resistance. Crop Prot. 19: 881-889.
    • (2000) Crop Prot , vol.19 , pp. 881-889
    • Devine, M.D.1    Shukla, A.2
  • 16
    • 8344220571 scopus 로고    scopus 로고
    • Crystal structure of the beta-subunit of acyl-CoA carboxylase: Structure-based engineering of substrate specificity
    • Diacovich L., Mitchell D.L., Pham H., Gago G., Melgar M.M., Khosla C., Gramajo H., Tsai S.C. (2004) Crystal structure of the beta-subunit of acyl-CoA carboxylase: structure-based engineering of substrate specificity. Biochemistry 43: 14027-14036.
    • (2004) Biochemistry , vol.43 , pp. 14027-14036
    • Diacovich, L.1    Mitchell, D.L.2    Pham, H.3    Gago, G.4    Melgar, M.M.5    Khosla, C.6    Gramajo, H.7    Tsai, S.C.8
  • 18
    • 33845571750 scopus 로고    scopus 로고
    • Role of malonyl-CoA in heart disease and the hypothalamic control of obesity
    • Folmes C.D., Lopaschuk G.D. (2007) Role of malonyl-CoA in heart disease and the hypothalamic control of obesity. Cardiovasc. Res. 73: 278-287.
    • (2007) Cardiovasc. Res , vol.73 , pp. 278-287
    • Folmes, C.D.1    Lopaschuk, G.D.2
  • 19
    • 2942718769 scopus 로고    scopus 로고
    • Identification and characterization of the first class of potent bacterial acetyl-CoA carboxylase inhibitors with antibacterial activity
    • Freiberg C., Brunner N.A., Schiffer G., Lampe T., Pohlmann J., Brands M., Raabe M., Habich D., Ziegelbauer K. (2004) Identification and characterization of the first class of potent bacterial acetyl-CoA carboxylase inhibitors with antibacterial activity. J. Biol. Chem. 279: 26066-26073.
    • (2004) J. Biol. Chem , vol.279 , pp. 26066-26073
    • Freiberg, C.1    Brunner, N.A.2    Schiffer, G.3    Lampe, T.4    Pohlmann, J.5    Brands, M.6    Raabe, M.7    Habich, D.8    Ziegelbauer, K.9
  • 20
    • 61349155536 scopus 로고    scopus 로고
    • Resveratrol inhibits fatty acid and triacylglycerol synthesis in rat hepatocytes
    • Gnoni G.V., Paglialonga G. (2009) Resveratrol inhibits fatty acid and triacylglycerol synthesis in rat hepatocytes. Eur. J. Clin. Invest. 39: 211-218.
    • (2009) Eur. J. Clin. Invest , vol.39 , pp. 211-218
    • Gnoni, G.V.1    Paglialonga, G.2
  • 21
    • 0031470643 scopus 로고    scopus 로고
    • Plastid-localized acetyl-CoA carboxylase of bread wheat is encoded by a single gene on each of the three ancestral chromosome sets
    • Gornicki P., Faris J., King I., Podkowinski J., Gill B., Haselkorn R. (1997) Plastid-localized acetyl-CoA carboxylase of bread wheat is encoded by a single gene on each of the three ancestral chromosome sets. Proc. Natl. Acad. Sci. USA 94: 14179-14184.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 14179-14184
    • Gornicki, P.1    Faris, J.2    King, I.3    Podkowinski, J.4    Gill, B.5    Haselkorn, R.6
  • 24
    • 43549102657 scopus 로고    scopus 로고
    • Microalgal triacylglycerols as feedstocks for biofuel production: Perspectives and advances
    • Hu Q., Sommerfeld M., Jarvis E., Ghirardi M., Posewitz M., Seibert M., Darzins A. (2008) Microalgal triacylglycerols as feedstocks for biofuel production: perspectives and advances. Plant J. 54: 621-639.
    • (2008) Plant J , vol.54 , pp. 621-639
    • Hu, Q.1    Sommerfeld, M.2    Jarvis, E.3    Ghirardi, M.4    Posewitz, M.5    Seibert, M.6    Darzins, A.7
  • 25
    • 0242300121 scopus 로고    scopus 로고
    • Hypothalamic malonyl-CoA as a mediator of feeding behavior
    • Hu Z., Cha S.H., Chohnan S., Lane M.D. (2003) Hypothalamic malonyl-CoA as a mediator of feeding behavior. Proc. Natl. Acad. Sci. USA 100: 12624-12629.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 12624-12629
    • Hu, Z.1    Cha, S.H.2    Chohnan, S.3    Lane, M.D.4
  • 27
    • 0037189489 scopus 로고    scopus 로고
    • The carboxyltransferase activity of the apicoplast acetyl-CoA carboxylase of Toxoplasma gondii is the target of aryloxyphenoxypropionate inhibitors
    • Jelenska J., Sirikhachornkit A., Haselkorn R., Gornicki P. (2002) The carboxyltransferase activity of the apicoplast acetyl-CoA carboxylase of Toxoplasma gondii is the target of aryloxyphenoxypropionate inhibitors. J. Biol. Chem. 277: 23208-23215.
    • (2002) J. Biol. Chem , vol.277 , pp. 23208-23215
    • Jelenska, J.1    Sirikhachornkit, A.2    Haselkorn, R.3    Gornicki, P.4
  • 29
    • 79551480612 scopus 로고    scopus 로고
    • Soraphen A, an inhibitor of acetyl CoA carboxylase activity, interferes with fatty acid elongation
    • Jump D.B., Torres-Gonzalez M., Olson L.K. (2011) Soraphen A, an inhibitor of acetyl CoA carboxylase activity, interferes with fatty acid elongation. Biochem. Pharmacol. 81: 649-660.
    • (2011) Biochem. Pharmacol , vol.81 , pp. 649-660
    • Jump, D.B.1    Torres-Gonzalez, M.2    Olson, L.K.3
  • 30
    • 0034002015 scopus 로고    scopus 로고
    • Coordinate regulation of the nuclear and plastidic genes coding for the subunits of the heteromeric acetyl-coenzyme A carboxylase
    • Ke J., Wen T.N., Nikolau B.J., Wurtele E.S. (2000) Coordinate regulation of the nuclear and plastidic genes coding for the subunits of the heteromeric acetyl-coenzyme A carboxylase. Plant Physiol. 122: 1057-1071.
    • (2000) Plant Physiol , vol.122 , pp. 1057-1071
    • Ke, J.1    Wen, T.N.2    Nikolau, B.J.3    Wurtele, E.S.4
  • 31
    • 3543139586 scopus 로고    scopus 로고
    • Increased fatty acid production in potato by engineering of acetyl-CoA carboxylase
    • Klaus D., Ohlrogge J.B., Neuhaus H.E., Dormann P. (2004) Increased fatty acid production in potato by engineering of acetyl-CoA carboxylase. Planta 219: 389-396.
    • (2004) Planta , vol.219 , pp. 389-396
    • Klaus, D.1    Ohlrogge, J.B.2    Neuhaus, H.E.3    Dormann, P.4
  • 32
    • 34250849659 scopus 로고    scopus 로고
    • Engineering central metabolic pathways for high-level flavonoid production in Escherichia coli
    • Leonard E., Lim K.H., Saw P.N., Koffas M.A. (2007) Engineering central metabolic pathways for high-level flavonoid production in Escherichia coli. Appl. Environ. Microbiol. 73: 3877-3886.
    • (2007) Appl. Environ. Microbiol , vol.73 , pp. 3877-3886
    • Leonard, E.1    Lim, K.H.2    Saw, P.N.3    Koffas, M.A.4
  • 33
    • 79955565417 scopus 로고    scopus 로고
    • Fatty acid production in genetically modified cyanobacteria
    • Liu X., Sheng J., Curtiss R. III (2011) Fatty acid production in genetically modified cyanobacteria. Proc. Natl. Acad. Sci. USA 108: 6899-6904.
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 6899-6904
    • Liu, X.1    Sheng, J.2    Curtiss, R.I.I.I.3
  • 34
    • 79961135642 scopus 로고    scopus 로고
    • Early evolution of the biotindependent carboxylase family
    • Lombard J., Moreira D. (2011) Early evolution of the biotindependent carboxylase family. BMC Evol. Biol. 11: 232.
    • (2011) BMC Evol. Biol , vol.11 , pp. 232
    • Lombard, J.1    Moreira, D.2
  • 35
    • 57049105699 scopus 로고    scopus 로고
    • Overproduction of free fatty acids in E. coli: Implications for biodiesel production
    • Lu X., Vora H., Khosla C. (2008) Overproduction of free fatty acids in E. coli: implications for biodiesel production. Metab. Eng. 10: 333-339.
    • (2008) Metab. Eng , vol.10 , pp. 333-339
    • Lu, X.1    Vora, H.2    Khosla, C.3
  • 38
    • 77950346738 scopus 로고    scopus 로고
    • A tale of two functions: Enzymatic activity and translational repression by carboxyltransferase
    • Meades G. Jr, Benson B.K., Grove A., Waldrop G.L. (2010) A tale of two functions: enzymatic activity and translational repression by carboxyltransferase. Nucl. Acids Res. 38: 1217-1227.
    • (2010) Nucl. Acids Res , vol.38 , pp. 1217-1227
    • Meades Jr., G.1    Benson, B.K.2    Grove, A.3    Waldrop, G.L.4
  • 39
    • 0017852044 scopus 로고
    • Acyl-coenzyme A carboxylase of the free-living nematode Turbatrix aceti. 2. Its catalytic properties and activation by monovalent cations
    • Meyer H., Meyer F. (1978) Acyl-coenzyme A carboxylase of the free-living nematode Turbatrix aceti. 2. Its catalytic properties and activation by monovalent cations. Biochemistry 17: 1828-1833.
    • (1978) Biochemistry , vol.17 , pp. 1828-1833
    • Meyer, H.1    Meyer, F.2
  • 44
    • 0033431683 scopus 로고    scopus 로고
    • Herbicide sensitivity determinant of wheat plastid acetyl-CoA carboxylase is located in a 400-amino acid fragment of the carboxyltransferase domain
    • Nikolskaya T., Zagnitko O., Tevzadze G., Haselkorn R., Gornicki P. (1999) Herbicide sensitivity determinant of wheat plastid acetyl-CoA carboxylase is located in a 400-amino acid fragment of the carboxyltransferase domain. Proc. Natl. Acad. Sci. USA 96: 14647-14651.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 14647-14651
    • Nikolskaya, T.1    Zagnitko, O.2    Tevzadze, G.3    Haselkorn, R.4    Gornicki, P.5
  • 47
    • 0030000697 scopus 로고    scopus 로고
    • Structure of a gene encoding a cytosolic acetyl-CoA carboxylase of hexaploid wheat
    • Podkowinski J., Sroga G.E., Haselkorn R., Gornicki P. (1996) Structure of a gene encoding a cytosolic acetyl-CoA carboxylase of hexaploid wheat. Proc. Natl. Acad. Sci. USA 93: 1870-1874.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 1870-1874
    • Podkowinski, J.1    Sroga, G.E.2    Haselkorn, R.3    Gornicki, P.4
  • 48
    • 0036139124 scopus 로고    scopus 로고
    • Carbon flux and fatty acid synthesis in plants
    • Rawsthorne S. (2002) Carbon flux and fatty acid synthesis in plants. Prog. Lipid Res. 41: 182-196.
    • (2002) Prog. Lipid Res , vol.41 , pp. 182-196
    • Rawsthorne, S.1
  • 49
    • 0031051393 scopus 로고    scopus 로고
    • Targeting of the Arabidopsis homomeric acetyl-coenzyme A carboxylase to plastids of rapeseeds
    • Roesler K., Shintani D., Savage L., Boddupalli S., Ohlrogge J. (1997) Targeting of the Arabidopsis homomeric acetyl-coenzyme A carboxylase to plastids of rapeseeds. Plant. Physiol. 113: 75-81.
    • (1997) Plant. Physiol , vol.113 , pp. 75-81
    • Roesler, K.1    Shintani, D.2    Savage, L.3    Boddupalli, S.4    Ohlrogge, J.5
  • 50
    • 4544228526 scopus 로고    scopus 로고
    • Plant acetyl-CoA carboxylase: Structure, biosynthesis, regulation, and gene manipulation for plant breeding
    • Sasaki Y., Nagano Y. (2004) Plant acetyl-CoA carboxylase: structure, biosynthesis, regulation, and gene manipulation for plant breeding. Biosci. Biotechnol. Biochem. 68: 1175-1184.
    • (2004) Biosci. Biotechnol. Biochem , vol.68 , pp. 1175-1184
    • Sasaki, Y.1    Nagano, Y.2
  • 52
    • 77957358900 scopus 로고    scopus 로고
    • A look back at the U.S. Department of Energy's Aquatic Species Program - Biodiesel from algae
    • Colorado
    • Sheehan J., Dunahay T., Benemann J., Roessler P. (1998) A look back at the U.S. Department of Energy's Aquatic Species Program - Biodiesel from algae. Nat. Renew. Ener. Lab., Colorado: 1-3.
    • (1998) Nat. Renew. Ener. Lab , pp. 1-3
    • Sheehan, J.1    Dunahay, T.2    Benemann, J.3    Roessler, P.4
  • 53
    • 0031177756 scopus 로고    scopus 로고
    • Antisense expression and overexpression of biotin carboxylase in tobacco leaves
    • Shintani D., Roesler K., Shorrosh B., Savage L., Ohlrogge J. (1997) Antisense expression and overexpression of biotin carboxylase in tobacco leaves. Plant Physiol. 114: 881-886.
    • (1997) Plant Physiol , vol.114 , pp. 881-886
    • Shintani, D.1    Roesler, K.2    Shorrosh, B.3    Savage, L.4    Ohlrogge, J.5
  • 54
    • 75849126252 scopus 로고    scopus 로고
    • The hydroxypropionate pathway of CO2 fixation: Fait accompli
    • Tabita F.R. (2009) The hydroxypropionate pathway of CO2 fixation: Fait accompli. Proc. Natl. Acad. Sci. USA 106: 21015-21016.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 21015-21016
    • Tabita, F.R.1
  • 55
    • 0038646820 scopus 로고    scopus 로고
    • Both antisense and sense expression of biotin carboxyl carrier protein isoform 2 inactivates the plastid acetyl-coenzyme A carboxylase in Arabidopsis thaliana
    • Thelen J.J., Ohlrogge J.B. (2002) Both antisense and sense expression of biotin carboxyl carrier protein isoform 2 inactivates the plastid acetyl-coenzyme A carboxylase in Arabidopsis thaliana. Plant J. 32: 419-431.
    • (2002) Plant J , vol.32 , pp. 419-431
    • Thelen, J.J.1    Ohlrogge, J.B.2
  • 56
    • 23944509003 scopus 로고    scopus 로고
    • Acetyl-coenzyme A carboxylase: Crucial metabolic enzyme and attractive target for drug discovery
    • Tong L. (2005) Acetyl-coenzyme A carboxylase: crucial metabolic enzyme and attractive target for drug discovery. Cell Mol. Life Sci. 62: 1784-1803.
    • (2005) Cell Mol. Life Sci , vol.62 , pp. 1784-1803
    • Tong, L.1
  • 57
    • 33751579134 scopus 로고    scopus 로고
    • Acetyl-coenzyme A carboxylases: Versatile targets for drug discovery
    • Tong L., Harwood H.J. Jr. (2006) Acetyl-coenzyme A carboxylases: versatile targets for drug discovery. J. Cell Biochem. 99: 1476-88.
    • (2006) J. Cell Biochem , vol.99 , pp. 1476-1488
    • Tong, L.1    Harwood Jr., H.J.2
  • 58
    • 0035852295 scopus 로고    scopus 로고
    • Biogenesis and origin of thylakoid membranes
    • Vothknecht U.C., Westhoff P. (2001) Biogenesis and origin of thylakoid membranes. Biochim. Biophys. Acta 1541: 91-101.
    • (2001) Biochim. Biophys. Acta , vol.1541 , pp. 91-101
    • Vothknecht, U.C.1    Westhoff, P.2
  • 59
    • 67649249777 scopus 로고    scopus 로고
    • Smaller is better for antibiotic discovery
    • Waldrop G.L. (2009) Smaller is better for antibiotic discovery. ACS Chem. Biol. 4: 397-399.
    • (2009) ACS Chem. Biol , vol.4 , pp. 397-399
    • Waldrop, G.L.1
  • 60
    • 35848936305 scopus 로고    scopus 로고
    • The soybean Dof-type transcription factor genes, GmDof4 and GmDof11, enhance lipid content in the seeds of transgenic Arabidopsis plants
    • Wang H.W., Zhang B., Hao Y.J., Huang J., Tian A.G., Liao Y., Zhang J.S., Chen S.Y. (2007) The soybean Dof-type transcription factor genes, GmDof4 and GmDof11, enhance lipid content in the seeds of transgenic Arabidopsis plants. Plant J. 52: 716-729.
    • (2007) Plant J , vol.52 , pp. 716-729
    • Wang, H.W.1    Zhang, B.2    Hao, Y.J.3    Huang, J.4    Tian, A.G.5    Liao, Y.6    Zhang, J.S.7    Chen, S.Y.8
  • 62
    • 0035810923 scopus 로고    scopus 로고
    • An isoleucine/leucine residue in the carboxyltransferase domain of acetyl-CoA carboxylase is critical for interaction with aryloxyphenoxypropionate and cyclohexanedione inhibitors
    • Zagnitko O., Jelenska J., Tevzadze G., Haselkorn R., Gornicki P. (2001) An isoleucine/leucine residue in the carboxyltransferase domain of acetyl-CoA carboxylase is critical for interaction with aryloxyphenoxypropionate and cyclohexanedione inhibitors. Proc. Natl. Acad. Sci. USA 98: 6617-6622.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 6617-6622
    • Zagnitko, O.1    Jelenska, J.2    Tevzadze, G.3    Haselkorn, R.4    Gornicki, P.5
  • 63
    • 75849119861 scopus 로고    scopus 로고
    • Identifying the missing steps of the autotrophic 3-hydroxypropionate CO2 fixation cycle in Chloroflexus aurantiacus
    • Zarzycki J., Brecht V., Muller M., Fuchs G. (2009) Identifying the missing steps of the autotrophic 3-hydroxypropionate CO2 fixation cycle in Chloroflexus aurantiacus. Proc. Natl. Acad. Sci. USA 106: 21317-21322.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 21317-21322
    • Zarzycki, J.1    Brecht, V.2    Muller, M.3    Fuchs, G.4
  • 64
    • 63649137435 scopus 로고    scopus 로고
    • Improving cellular malonyl-CoA level in Escherichia coli via metabolic engineering
    • Zha W., Rubin-Pitel S.B., Shao Z., Zhao H. (2009) Improving cellular malonyl-CoA level in Escherichia coli via metabolic engineering. Metab. Eng. 11: 192-198.
    • (2009) Metab. Eng , vol.11 , pp. 192-198
    • Zha, W.1    Rubin-Pitel, S.B.2    Shao, Z.3    Zhao, H.4
  • 65
    • 1942533548 scopus 로고    scopus 로고
    • Molecular basis for the inhibition of the carboxyltransferase domain of acetylcoenzyme-A carboxylase by haloxyfop and diclofop
    • Zhang H., Tweel B., Tong L. (2004) Molecular basis for the inhibition of the carboxyltransferase domain of acetylcoenzyme-A carboxylase by haloxyfop and diclofop. Proc. Natl. Acad. Sci. USA 101: 5910-5915.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 5910-5915
    • Zhang, H.1    Tweel, B.2    Tong, L.3
  • 66
    • 0037470947 scopus 로고    scopus 로고
    • Crystal structure of the carboxyltransferase domain of acetyl-coenzyme A carboxylase
    • Zhang H., Yang Z., Shen Y., Tong L. (2003) Crystal structure of the carboxyltransferase domain of acetyl-coenzyme A carboxylase. Science 299: 2064-2067.
    • (2003) Science , vol.299 , pp. 2064-2067
    • Zhang, H.1    Yang, Z.2    Shen, Y.3    Tong, L.4
  • 67
    • 79954444622 scopus 로고    scopus 로고
    • Computational simulations of structural role of the active-site W374C mutation of acetyl-coenzyme-A carboxylase: Multidrug resistance mechanism
    • Zhu X.L., Yang W.C., Yu N.X., Yang S.G., Yang G.F. (2011) Computational simulations of structural role of the active-site W374C mutation of acetyl-coenzyme-A carboxylase: multidrug resistance mechanism. J. Mol. Model. 17: 495-503.
    • (2011) J. Mol. Model , vol.17 , pp. 495-503
    • Zhu, X.L.1    Yang, W.C.2    Yu, N.X.3    Yang, S.G.4    Yang, G.F.5
  • 69
    • 0033539685 scopus 로고    scopus 로고
    • Growth of Toxoplasma gondii is inhibited by aryloxyphenoxypropionate herbicides targeting acetyl-CoA carboxylase
    • Zuther E., Johnson J.J., Haselkorn R., McLeod R., Gornicki P. (1999) Growth of Toxoplasma gondii is inhibited by aryloxyphenoxypropionate herbicides targeting acetyl-CoA carboxylase. Proc. Natl. Acad. Sci. USA 96: 13387-13392.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 13387-13392
    • Zuther, E.1    Johnson, J.J.2    Haselkorn, R.3    McLeod, R.4    Gornicki, P.5


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