메뉴 건너뛰기




Volumn 81, Issue 8, 2012, Pages 733-744

The kallikrein-kinin system in diabetic nephropathy

Author keywords

ACE inhibitors; bradykinin; diabetic nephropathy; nitric oxide; oxidative stress

Indexed keywords

ARGININE; BRADYKININ B1 RECEPTOR; BRADYKININ B2 RECEPTOR; CALCIUM ION; CAPTOPRIL; CICAPROST; DIPEPTIDYL CARBOXYPEPTIDASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; INDUCIBLE NITRIC OXIDE SYNTHASE; IRBESARTAN; KALLIKREIN; KININ; LISINOPRIL; LOSARTAN; NEPHRIN; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE; PLACEBO; TRANDOLAPRIL; VERAPAMIL;

EID: 84859428917     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2011.499     Document Type: Review
Times cited : (43)

References (150)
  • 1
    • 0021175531 scopus 로고
    • Hydrolysis of substance P and neurotensin by converting enzyme and neutral endopeptidase
    • DOI 10.1016/0196-9781(84)90020-2
    • Skidgel RA, Engelbrecht S, Johnson AR et al. Hydrolysis of substance p and neurotensin by converting enzyme and neutral endopeptidase. Peptides 1984; 5: 769-776. (Pubitemid 14058557)
    • (1984) Peptides , vol.5 , Issue.4 , pp. 769-776
    • Skidgel, R.A.1    Engelbrecht, S.2    Johnson, A.R.3    Erdos, E.G.4
  • 2
    • 67349177072 scopus 로고    scopus 로고
    • The kallikrein-kinin system in health and in diseases of the kidney
    • Kakoki M, Smithies O. The kallikrein-kinin system in health and in diseases of the kidney. Kidney Int 2009; 75: 1019-1030.
    • (2009) Kidney Int , vol.75 , pp. 1019-1030
    • Kakoki, M.1    Smithies, O.2
  • 3
    • 0027175193 scopus 로고
    • Differences in the properties and enzymatic specificities of the two active sites of angiotensin I-converting enzyme (kininase II). Studies with bradykinin and other natural peptides
    • Jaspard E, Wei L, Alhenc-Gelas F. Differences in the properties and enzymatic specificities of the two active sites of angiotensin I-converting enzyme (kininase II). Studies with bradykinin and other natural peptides. J Biol Chem 1993; 268: 9496-9503. (Pubitemid 23146003)
    • (1993) Journal of Biological Chemistry , vol.268 , Issue.13 , pp. 9496-9503
    • Jaspard, E.1    Wei, L.2    Alhenc-Gelas, F.3
  • 4
    • 0024437204 scopus 로고
    • Role of angiotensin converting enzyme and other peptidases in in vivo metabolism of kinins
    • Ishida H, Scicli AG, Carretero OA. Role of angiotensin converting enzyme and other peptidases in in vivo metabolism of kinins. Hypertension 1989; 14: 322-327. (Pubitemid 19220009)
    • (1989) Hypertension , vol.14 , Issue.3 , pp. 322-327
    • Ishida, H.1    Scicli, A.G.2    Carretero, O.A.3
  • 5
    • 0033667449 scopus 로고    scopus 로고
    • Importance of quantitative genetic variations in the etiology of hypertension
    • Smithies O, Kim HS, Takahashi N et al. Importance of quantitative genetic variations in the etiology of hypertension. Kidney Int 2000; 58: 2265-2280.
    • (2000) Kidney Int , vol.58 , pp. 2265-2280
    • Smithies, O.1    Kim, H.S.2    Takahashi, N.3
  • 6
    • 0038577275 scopus 로고    scopus 로고
    • Minireview: Computer simulations of blood pressure regulation by the renin-angiotensin system
    • DOI 10.1210/en.2002-221045
    • Takahashi N, Hagaman JR, Kim HS et al. Minireview: computer simulations of blood pressure regulation by the renin-angiotensin system. Endocrinology 2003; 144: 2184-2190. (Pubitemid 36629864)
    • (2003) Endocrinology , vol.144 , Issue.6 , pp. 2184-2190
    • Takahashi, N.1    Hagaman, J.R.2    Kim, H.-S.3    Smithies, O.4
  • 7
    • 0028274151 scopus 로고
    • Effects of converting enzyme inhibitors on angiotensin and bradykinin peptides
    • Campbell DJ, Kladis A, Duncan AM. Effects of converting enzyme inhibitors on angiotensin and bradykinin peptides. Hypertension 1994; 23: 439-449. (Pubitemid 24102039)
    • (1994) Hypertension , vol.23 , Issue.4 , pp. 439-449
    • Campbell, D.J.1    Kladis, A.2    Duncan, A.-M.3
  • 8
    • 0025165779 scopus 로고
    • An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels
    • Rigat B, Hubert C, Alhenc-Gelas F et al. An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels. J Clin Invest 1990; 86: 1343-1346. (Pubitemid 20370444)
    • (1990) Journal of Clinical Investigation , vol.86 , Issue.4 , pp. 1343-1346
    • Rigat, B.1    Hubert, C.2    Alhenc-Gelas, F.3    Cambien, F.4    Corvol, P.5    Soubrier, F.6
  • 9
    • 0029003007 scopus 로고
    • Angiotensin-converting enzyme gene polymorphism has no influence on the circulating renin-angiotensin-aldosterone system or blood pressure in normotensive subjects
    • Lachurie ML, Azizi M, Guyene TT et al. Angiotensin-converting enzyme gene polymorphism has no influence on the circulating renin-angiotensin-aldosterone system or blood pressure in normotensive subjects. Circulation 1995; 91: 2933-2942.
    • (1995) Circulation , vol.91 , pp. 2933-2942
    • Lachurie, M.L.1    Azizi, M.2    Guyene, T.T.3
  • 11
    • 0031960407 scopus 로고    scopus 로고
    • Diabetic nephropathy and the insertion/deletion polymorphism of the angiotensin-converting enzyme gene
    • DOI 10.1093/ndt/13.5.1125
    • Tarnow L, Gluud C, Parving HH. Diabetic nephropathy and the insertion/ deletion polymorphism of the angiotensin-converting enzyme gene. Nephrol Dial Transplant 1998; 13: 1125-1130. (Pubitemid 28227184)
    • (1998) Nephrology Dialysis Transplantation , vol.13 , Issue.5 , pp. 1125-1130
    • Tarnow, L.1    Gluud, C.2    Parving, H.-H.3
  • 12
    • 33747891862 scopus 로고    scopus 로고
    • A common variant in the ACE gene is associated with peripheral neuropathy in women with type 2 diabetes mellitus
    • DOI 10.1016/j.jdiacomp.2005.07.010, PII S1056872705000954
    • Stephens JW, Dhamrait SS, Acharya J et al. A common variant in the ACE gene is associated with peripheral neuropathy in women with type 2 diabetes mellitus. J Diabet Compl 2006; 20: 317-321. (Pubitemid 44292531)
    • (2006) Journal of Diabetes and its Complications , vol.20 , Issue.5 , pp. 317-321
    • Stephens, J.W.1    Dhamrait, S.S.2    Acharya, J.3    Humphries, S.E.4    Hurel, S.J.5
  • 14
    • 0026675062 scopus 로고
    • Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction
    • Cambien F, Poirier O, Lecerf L et al. Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction. Nature 1992; 359: 641-644.
    • (1992) Nature , vol.359 , pp. 641-644
    • Cambien, F.1    Poirier, O.2    Lecerf, L.3
  • 15
    • 0030758043 scopus 로고    scopus 로고
    • Polymorphism of the angiotensin-converting enzyme (ACE) gene in patients with thrombotic brain infarction
    • DOI 10.1016/S0021-9150(97)00080-4, PII S0021915097000804
    • Doi Y, Yoshinari M, Yoshizumi H et al. Polymorphism of the angiotensin-converting enzyme (ACE) gene in patients with thrombotic brain infarction. Atherosclerosis 1997; 132: 145-150. (Pubitemid 27311005)
    • (1997) Atherosclerosis , vol.132 , Issue.2 , pp. 145-150
    • Doi, Y.1    Yoshinari, M.2    Yoshizumi, H.3    Ibayashi, S.4    Wakisaka, M.5    Fujishima, M.6
  • 16
    • 0034702913 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme insertion/deletion polymorphism modulates the human in vivo metabolism of bradykinin
    • Murphey LJ, Gainer JV, Vaughan DE et al. Angiotensin-converting enzyme insertion/deletion polymorphism modulates the human in vivo metabolism of bradykinin. Circulation 2000; 102: 829-832.
    • (2000) Circulation , vol.102 , pp. 829-832
    • Murphey, L.J.1    Gainer, J.V.2    Vaughan, D.E.3
  • 17
    • 77049087281 scopus 로고    scopus 로고
    • Plasma kallikrein and angiotensin I-converting enzyme N- and C-terminal domain activities are modulated by the insertion/deletion polymorphism
    • Almeida SS, Barros CC, Moraes MR et al. Plasma kallikrein and angiotensin I-converting enzyme N- and C-terminal domain activities are modulated by the insertion/deletion polymorphism. Neuropeptides 2010; 44: 139-143.
    • (2010) Neuropeptides , vol.44 , pp. 139-143
    • Almeida, S.S.1    Barros, C.C.2    Moraes, M.R.3
  • 20
    • 0027517659 scopus 로고
    • The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy
    • DOI 10.1056/NEJM199311113292004
    • Lewis EJ, Hunsicker LG, Bain RP et al. The effect of angiotensin- converting enzyme inhibition on diabetic nephropathy. The Collaborative Study Group. N Engl J Med 1993; 329: 1456-1462. (Pubitemid 23335891)
    • (1993) New England Journal of Medicine , vol.329 , Issue.20 , pp. 1456-1462
    • Lewis, E.J.1    Hunsicker, L.G.2    Bain, R.P.3    Rohde, R.D.4
  • 22
    • 77956644609 scopus 로고    scopus 로고
    • The RAAS in the pathogenesis and treatment of diabetic nephropathy
    • Ruggenenti P, Cravedi P, Remuzzi G. The RAAS in the pathogenesis and treatment of diabetic nephropathy. Nat Rev Nephrol 2010; 6: 319-330.
    • (2010) Nat Rev Nephrol , vol.6 , pp. 319-330
    • Ruggenenti, P.1    Cravedi, P.2    Remuzzi, G.3
  • 23
    • 0035922441 scopus 로고    scopus 로고
    • Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy
    • Brenner BM, Cooper ME, de Zeeuw D et al. Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. N Engl J Med 2001; 345: 861-869.
    • (2001) N Engl J Med , vol.345 , pp. 861-869
    • Brenner, B.M.1    Cooper, M.E.2    De Zeeuw, D.3
  • 24
    • 0035922447 scopus 로고    scopus 로고
    • Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes
    • Lewis EJ, Hunsicker LG, Clarke WR et al. Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes. N Engl J Med 2001; 345: 851-860.
    • (2001) N Engl J Med , vol.345 , pp. 851-860
    • Lewis, E.J.1    Hunsicker, L.G.2    Clarke, W.R.3
  • 25
    • 0043068157 scopus 로고    scopus 로고
    • The intrarenal renin-angiotensin system and diabetic nephropathy
    • DOI 10.1016/S1043-2760(03)00111-5
    • Carey RM, Siragy HM. The intrarenal renin-angiotensin system and diabetic nephropathy. Trends Endocrinol Metab 2003; 14: 274-281. (Pubitemid 36992197)
    • (2003) Trends in Endocrinology and Metabolism , vol.14 , Issue.6 , pp. 274-281
    • Carey, R.M.1    Siragy, H.M.2
  • 26
    • 1642545117 scopus 로고    scopus 로고
    • The intrarenal renin-angiotensin system in hypertension
    • DOI 10.1111/j.1523-1755.2004.00539.x
    • Navar LG. The intrarenal renin-angiotensin system in hypertension. Kidney Int 2004; 65: 1522-1532. (Pubitemid 38407000)
    • (2004) Kidney International , vol.65 , Issue.4 , pp. 1522-1532
    • Navar, L.G.1
  • 27
    • 0033038821 scopus 로고    scopus 로고
    • Increased bradykinin and 'normal' angiotensin peptide levels in diabetic Sprague-Dawley and transgenic (mRen-2)27 rats
    • DOI 10.1046/j.1523-1755.1999.00519.x
    • Campbell DJ, Kelly DJ, Wilkinson-Berka JL et al. Increased bradykinin and 'normal' angiotensin peptide levels in diabetic Sprague-Dawley and transgenic (mRen-2)27 rats. Kidney Int 1999; 56: 211-221. (Pubitemid 29300537)
    • (1999) Kidney International , vol.56 , Issue.1 , pp. 211-221
    • Campbell, D.J.1    Kelly, D.J.2    Wilkinson-Berka, J.L.3    Cooper, M.E.4    Skinner, S.L.5
  • 29
    • 34748859681 scopus 로고    scopus 로고
    • The intrarenal renin-angiotensin system: From physiology to the pathobiology of hypertension and kidney disease
    • DOI 10.1124/pr.59.3.3
    • Kobori H, Nangaku M, Navar LG et al. The intrarenal renin-angiotensin system: from physiology to the pathobiology of hypertension and kidney disease. Pharmacol Rev 2007; 59: 251-287. (Pubitemid 47481436)
    • (2007) Pharmacological Reviews , vol.59 , Issue.3 , pp. 251-287
    • Kobori, H.1    Nangaku, M.2    Navar, L.G.3    Nishiyama, A.4
  • 31
    • 0037336745 scopus 로고    scopus 로고
    • Myocardial uptake and biochemical and hemodynamic effects of ACE inhibitors in humans
    • DOI 10.1161/01.HYP.0000054976.67487.08
    • Zeitz CJ, Campbell DJ, Horowitz JD. Myocardial uptake and biochemical and hemodynamic effects of ACE inhibitors in humans. Hypertension 2003; 41: 482-487. (Pubitemid 36314620)
    • (2003) Hypertension , vol.41 , Issue.3 I , pp. 482-487
    • Zeitz, C.J.1    Campbell, D.J.2    Horowitz, J.D.3
  • 34
    • 4644278885 scopus 로고    scopus 로고
    • Nephroprotection in Zucker diabetic fatty rats by vasopeptidase inhibition is partly bradykinin B2 receptor dependent
    • DOI 10.1038/sj.bjp.0705884
    • Schafer S, Schmidts HL, Bleich M et al. Nephroprotection in zucker diabetic fatty rats by vasopeptidase inhibition is partly bradykinin B2 receptor dependent. Br J Pharmacol 2004; 143: 27-32. (Pubitemid 39280021)
    • (2004) British Journal of Pharmacology , vol.143 , Issue.1 , pp. 27-32
    • Schafer, S.1    Schmidts, H.-L.2    Bleich, M.3    Busch, A.E.4    Linz, W.5
  • 35
    • 45149109175 scopus 로고    scopus 로고
    • Pharmacological blockade of B2-kinin receptor reduces renal protective effect of angiotensin-converting enzyme inhibition in db/db mice model
    • Buleon M, Allard J, Jaafar A et al. Pharmacological blockade of B2-kinin receptor reduces renal protective effect of angiotensin-converting enzyme inhibition in db/db mice model. Am J Physiol Renal Physiol 2008; 294: F1249-F1256.
    • (2008) Am J Physiol Renal Physiol , vol.294
    • Buleon, M.1    Allard, J.2    Jaafar, A.3
  • 36
    • 12844288884 scopus 로고    scopus 로고
    • Losartan increases bradykinin levels in hypertensive humans
    • DOI 10.1161/01.CIR.0000153269.07762.3B
    • Campbell DJ, Krum H, Esler MD. Losartan increases bradykinin levels in hypertensive humans. Circulation 2005; 111: 315-320. (Pubitemid 40165338)
    • (2005) Circulation , vol.111 , Issue.3 , pp. 315-320
    • Campbell, D.J.1    Krum, H.2    Esler, M.D.3
  • 37
    • 0031003230 scopus 로고    scopus 로고
    • Effects of angiotensin-converting enzyme inhibitors and angiotensin II type 1 receptor antagonists in rats with heart failure: Role of kinins and angiotensin II type 2 receptors
    • Liu YH, Yang XP, Sharov VG et al. Effects of angiotensin-converting enzyme inhibitors and angiotensin II type 1 receptor antagonists in rats with heart failure. Role of kinins and angiotensin II type 2 receptors. J Clin Invest 1997; 99: 1926-1935. (Pubitemid 27175940)
    • (1997) Journal of Clinical Investigation , vol.99 , Issue.8 , pp. 1926-1935
    • Liu, Y.-H.1    Yang, X.-P.2    Sharov, V.G.3    Nass, O.4    Sabbah, H.N.5    Peterson, E.6    Carretero, O.A.7
  • 38
    • 0030610587 scopus 로고    scopus 로고
    • 2) angiotensin receptor mediates renal production of nitric oxide in conscious rats
    • Siragy HM, Carey RM. The subtype 2 (AT2) angiotensin receptor mediates renal production of nitric oxide in conscious rats. J Clin Invest 1997; 100: 264-269. (Pubitemid 27349072)
    • (1997) Journal of Clinical Investigation , vol.100 , Issue.2 , pp. 264-269
    • Siragy, H.M.1    Carey, R.M.2
  • 40
    • 0038673089 scopus 로고    scopus 로고
    • 2-receptordependent mechanism
    • DOI 10.1161/01.HYP.0000064942.77814.26
    • Hornig B, Kohler C, Schlink D et al. AT1-receptor antagonism improves endothelial function in coronary artery disease by a bradykinin/B2-receptor- dependent mechanism. Hypertension 2003; 41: 1092-1095. (Pubitemid 36548608)
    • (2003) Hypertension , vol.41 , Issue.5 , pp. 1092-1095
    • Hornig, B.1    Kohler, C.2    Schlink, D.3    Tatge, H.4    Drexler, H.5
  • 42
    • 53749103611 scopus 로고    scopus 로고
    • Angiotensin converting enzyme insertion/deletion polymorphism and renoprotection in diabetic and nondiabetic nephropathies
    • Ruggenenti P, Bettinaglio P, Pinares F et al. Angiotensin converting enzyme insertion/deletion polymorphism and renoprotection in diabetic and nondiabetic nephropathies. Clin J Am Soc Nephrol 2008; 3: 1511-1525.
    • (2008) Clin J Am Soc Nephrol , vol.3 , pp. 1511-1525
    • Ruggenenti, P.1    Bettinaglio, P.2    Pinares, F.3
  • 43
    • 0031678591 scopus 로고    scopus 로고
    • Effect of angiotensin-converting enzyme (ACE) gene polymorphism on progression of renal disease and the influence of ACE inhibition in IDDM patients: Findings from the EUCLID randomized controlled trial
    • Penno G, Chaturvedi N, Talmud PJ et al. Effect of angiotensin-converting enzyme (ACE) gene polymorphism on progression of renal disease and the influence of ACE inhibition in IDDM patients: Findings from the EUCLID Randomized Controlled Trial. EURODIAB Controlled Trial of Lisinopril in IDDM. Diabetes 1998; 47: 1507-1511. (Pubitemid 28396957)
    • (1998) Diabetes , vol.47 , Issue.9 , pp. 1507-1511
    • Penno, G.1    Chaturvedi, N.2    Talmud, P.J.3    Cotroneo, P.4    Manto, A.5    Nannipieri, M.6    Luong, L.-A.7    Fuller, J.H.8
  • 46
    • 33646133656 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme (ACE) inhibition in type 2, diabetic patients: Interaction with ace insertion/ deletion polymorphism
    • So WY, Ma RC, Ozaki R et al. Angiotensin-converting enzyme (ACE) inhibition in type 2, diabetic patients: interaction with ace insertion/ deletion polymorphism. Kidney Int 2006; 69: 1438-1443.
    • (2006) Kidney Int , vol.69 , pp. 1438-1443
    • So, W.Y.1    Ma, R.C.2    Ozaki, R.3
  • 47
    • 44349177550 scopus 로고    scopus 로고
    • ACE gene polymorphism and losartan treatment in type 2 diabetic patients with nephropathy
    • Parving HH, de Zeeuw D, Cooper ME et al. ACE gene polymorphism and losartan treatment in type 2 diabetic patients with nephropathy. J Am Soc Nephrol 2008; 19: 771-779.
    • (2008) J Am Soc Nephrol , vol.19 , pp. 771-779
    • Parving, H.H.1    De Zeeuw, D.2    Cooper, M.E.3
  • 48
    • 0035109684 scopus 로고    scopus 로고
    • Classification of kinin receptors
    • Regoli D, Rizzi A, Perron SI et al. Classification of kinin receptors. Biol Chem 2001; 382: 31-35.
    • (2001) Biol Chem , vol.382 , pp. 31-35
    • Regoli, D.1    Rizzi, A.2    Perron, S.I.3
  • 49
    • 14144251086 scopus 로고    scopus 로고
    • International union of pharmacology. XLV. Classification of the kinin receptor family: From molecular mechanisms to pathophysiological consequences
    • DOI 10.1124/pr.57.1.2
    • Leeb-Lundberg LM, Marceau F, Muller-Esterl W et al. International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol Rev 2005; 57: 27-77. (Pubitemid 40283969)
    • (2005) Pharmacological Reviews , vol.57 , Issue.1 , pp. 27-77
    • Leeb-Lundberg, L.M.F.1    Marceau, F.2    Muller-Esterl, W.3    Pettibone, D.J.4    Zuraw, B.L.5
  • 51
    • 0032579513 scopus 로고    scopus 로고
    • 1 receptor gene in inflammation
    • DOI 10.1074/jbc.273.5.2784
    • Ni A, Chao L, Chao J. Transcription factor nuclear factor kappaB regulates the inducible expression of the human B1 receptor gene in inflammation. J Biol Chem 1998; 273: 2784-2791. (Pubitemid 28133925)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.5 , pp. 2784-2791
    • Ni, A.1    Chao, L.2    Chao, J.3
  • 55
    • 78249252379 scopus 로고    scopus 로고
    • Kinin B1 receptor upregulation by angiotensin II and endothelin-1 in rat vascular smooth muscle cells: Receptors and mechanisms
    • Morand-Contant M, Anand-Srivastava MB, Couture R. Kinin B1 receptor upregulation by angiotensin II and endothelin-1 in rat vascular smooth muscle cells: receptors and mechanisms. Am J Physiol Heart Circ Physiol 2010; 299: H1625-H1632.
    • (2010) Am J Physiol Heart Circ Physiol , vol.299
    • Morand-Contant, M.1    Anand-Srivastava, M.B.2    Couture, R.3
  • 58
    • 0029895045 scopus 로고    scopus 로고
    • 1 receptor gene for kinins (BDKRB1)
    • DOI 10.1006/geno.1996.0213
    • Bachvarov DR, Hess JF, Menke JG et al. Structure and genomic organization of the human B1 receptor gene for kinins (BDKRB1). Genomics 1996; 33: 374-381. (Pubitemid 26159854)
    • (1996) Genomics , vol.33 , Issue.3 , pp. 374-381
    • Bachvarov, D.R.1    Hess, J.F.2    Menke, J.G.3    Larrivee, J.-F.4    Marceau, F.5
  • 61
    • 66649088302 scopus 로고    scopus 로고
    • Gene deletion of the kinin receptor B1 attenuates cardiac inflammation and fibrosis during the development of experimental diabetic cardiomyopathy
    • Westermann D, Walther T, Savvatis K et al. Gene deletion of the kinin receptor B1 attenuates cardiac inflammation and fibrosis during the development of experimental diabetic cardiomyopathy. Diabetes 2009; 58: 1373-1381.
    • (2009) Diabetes , vol.58 , pp. 1373-1381
    • Westermann, D.1    Walther, T.2    Savvatis, K.3
  • 62
    • 37649001672 scopus 로고    scopus 로고
    • Hemodynamic and renal involvement of B1 and B2 kinin receptors during the acute phase of endotoxin shock in mice
    • Seguin T, Buleon M, Destrube M et al. Hemodynamic and renal involvement of B1 and B2 kinin receptors during the acute phase of endotoxin shock in mice. Int Immunopharmacol 2008; 8: 217-221.
    • (2008) Int Immunopharmacol , vol.8 , pp. 217-221
    • Seguin, T.1    Buleon, M.2    Destrube, M.3
  • 63
    • 57249103325 scopus 로고    scopus 로고
    • The non-peptide kinin receptor antagonists FR 173657 and SSR 240612: Preclinical evidence for the treatment of skin inflammation
    • Pietrovski EF, Otuki MF, Regoli D et al. The non-peptide kinin receptor antagonists FR 173657 and SSR 240612: preclinical evidence for the treatment of skin inflammation. Regul Pept 2009; 152: 67-72.
    • (2009) Regul Pept , vol.152 , pp. 67-72
    • Pietrovski, E.F.1    Otuki, M.F.2    Regoli, D.3
  • 64
    • 68249129012 scopus 로고    scopus 로고
    • Kallikrein protects against microalbuminuria in experimental type 1 diabetes
    • Bodin S, Chollet C, Goncalves-Mendes N et al. Kallikrein protects against microalbuminuria in experimental type 1 diabetes. Kidney Int 2009; 76: 395-403.
    • (2009) Kidney Int , vol.76 , pp. 395-403
    • Bodin, S.1    Chollet, C.2    Goncalves-Mendes, N.3
  • 65
    • 0036891715 scopus 로고    scopus 로고
    • Diabetes modulates the expression of glomerular kinin receptors
    • DOI 10.1016/S1567-5769(02)00188-1, PII S1567576902001881
    • Christopher J, Jaffa AA. Diabetes modulates the expression of glomerular kinin receptors. Int Immunopharmacol 2002; 2: 1771-1779. (Pubitemid 35373920)
    • (2002) International Immunopharmacology , vol.2 , Issue.13-14 , pp. 1771-1779
    • Christopher, J.1    Jaffa, A.A.2
  • 67
    • 0030907296 scopus 로고    scopus 로고
    • A novel locus, Mody4, distal to D7Mit189 on chromosome 7 determines early-onset NIDDM in nonobese C57BL/6 (Akita) mutant mice
    • Yoshioka M, Kayo T, Ikeda T et al. A novel locus, Mody4, distal to D7Mit189 on chromosome 7 determines early-onset NIDDM in nonobese C57BL/6 (Akita) mutant mice. Diabetes 1997; 46: 887-894. (Pubitemid 27188269)
    • (1997) Diabetes , vol.46 , Issue.5 , pp. 887-894
    • Yoshioka, M.1    Kayo, T.2    Ikeda, T.3    Koizumi, A.4
  • 69
    • 0035014380 scopus 로고    scopus 로고
    • Regulation of B(2)-kinin receptors by glucose in vascular smooth muscle cells
    • Christopher J, Velarde V, Zhang D et al. Regulation of B(2)-kinin receptors by glucose in vascular smooth muscle cells. Am J Physiol Heart Circ Physiol 2001; 280: H1537-H1546.
    • (2001) Am J Physiol Heart Circ Physiol , vol.280
    • Christopher, J.1    Velarde, V.2    Zhang, D.3
  • 70
    • 77949267083 scopus 로고    scopus 로고
    • Increased tissue kallikrein levels in type 2 diabetes
    • Campbell DJ, Kladis A, Zhang Y et al. Increased tissue kallikrein levels in type 2 diabetes. Diabetologia 2010; 53: 779-785.
    • (2010) Diabetologia , vol.53 , pp. 779-785
    • Campbell, D.J.1    Kladis, A.2    Zhang, Y.3
  • 71
    • 33646408788 scopus 로고    scopus 로고
    • Senescence-associated phenotypes in Akita diabetic mice are enhanced by absence of bradykinin B2 receptors
    • Kakoki M, Kizer CM, Yi X et al. Senescence-associated phenotypes in Akita diabetic mice are enhanced by absence of bradykinin B2 receptors. J Clin Invest 2006; 116: 1302-1309.
    • (2006) J Clin Invest , vol.116 , pp. 1302-1309
    • Kakoki, M.1    Kizer, C.M.2    Yi, X.3
  • 74
    • 0035985324 scopus 로고    scopus 로고
    • 1 receptors in myocardial ischemia: Evidence from pharmacological blockade and gene knockout mice
    • DOI 10.1016/S1567-5769(02)00022-X, PII S156757690200022X
    • Lagneux C, Bader M, Pesquero JB et al. Detrimental implication of B1 receptors in myocardial ischemia: evidence from pharmacological blockade and gene knockout mice. Int Immunopharmacol 2002; 2: 815-822. (Pubitemid 34603126)
    • (2002) International Immunopharmacology , vol.2 , Issue.6 , pp. 815-822
    • Lagneux, C.1    Bader, M.2    Pesquero, J.B.3    Demenge, P.4    Ribuot, C.5
  • 76
    • 77953471168 scopus 로고    scopus 로고
    • Lack of both bradykinin B1 and B2 receptors enhances nephropathy, neuropathy, and bone mineral loss in Akita diabetic mice
    • Kakoki M, Sullivan KA, Backus C et al. Lack of both bradykinin B1 and B2 receptors enhances nephropathy, neuropathy, and bone mineral loss in Akita diabetic mice. Proc Natl Acad Sci USA 2010; 107: 10190-10195.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 10190-10195
    • Kakoki, M.1    Sullivan, K.A.2    Backus, C.3
  • 77
    • 34249781156 scopus 로고    scopus 로고
    • Tissue kallikrein reverses insulin resistance and attenuates nephropathy in diabetic rats by activation of phosphatidylinositol 3-kinase/protein kinase B and adenosine 50-monophosphate-activated protein kinase signaling pathways
    • DOI 10.1210/en.2006-0602
    • Yuan G, Deng J, Wang T et al. Tissue kallikrein reverses insulin resistance and attenuates nephropathy in diabetic rats by activation of phosphatidylinositol 3-kinase/protein kinase B and adenosine 50-monophosphate-activated protein kinase signaling pathways. Endocrinology 2007; 148: 2016-2026. (Pubitemid 46997049)
    • (2007) Endocrinology , vol.148 , Issue.5 , pp. 2016-2026
    • Yuan, G.1    Deng, J.2    Wang, T.3    Zhao, C.4    Xu, X.5    Wang, P.6    Voltz, J.W.7    Edin, M.L.8    Xiao, X.9    Chao, L.10    Chao, J.11    Zhang, X.A.12    Zeldin, D.C.13    Dao, W.W.14
  • 78
    • 0030175320 scopus 로고    scopus 로고
    • Polymorphisms in the gene for the human B2-bradykinin receptor. New tools in assessing a genetic risk for bradykinin-associated diseases
    • Braun A, Kammerer S, Maier E et al. Polymorphisms in the gene for the human B2-bradykinin receptor. New tools in assessing a genetic risk for bradykinin-associated diseases. Immunopharmacology 1996; 33: 32-35.
    • (1996) Immunopharmacology , vol.33 , pp. 32-35
    • Braun, A.1    Kammerer, S.2    Maier, E.3
  • 79
    • 0031019956 scopus 로고    scopus 로고
    • Analysis of an exon 1 polymorphism of the B2 bradykinin receptor gene and its transcript in normal subjects and patients with C1 inhibitor deficiency
    • DOI 10.1016/S0091-6749(97)70310-5
    • Lung CC, Chan EK, Zuraw BL. Analysis of an exon 1 polymorphism of the B2 bradykinin receptor gene and its transcript in normal subjects and patients with C1 inhibitor deficiency. J Allergy Clin Immunol 1997; 99: 134-146. (Pubitemid 27074907)
    • (1997) Journal of Allergy and Clinical Immunology , vol.99 , Issue.1 I , pp. 134-146
    • Lung, C.-C.1    Chan, E.K.L.2    Zuraw, B.L.3
  • 82
    • 38549114518 scopus 로고    scopus 로고
    • Bradykinin type 2 receptor BE1 genotype influences bradykinin-dependent vasodilation during angiotensin-converting enzyme inhibition
    • DOI 10.1161/HYPERTENSIONAHA.107.102574, PII 0000426820080200100007
    • Van Guilder GP, Pretorius M, Luther JM et al. Bradykinin type 2 receptor BE1 genotype influences bradykinin-dependent vasodilation during angiotensin-converting enzyme inhibition. Hypertension 2008; 51: 454-459. (Pubitemid 351156432)
    • (2008) Hypertension , vol.51 , Issue.2 PART 2 , pp. 454-459
    • Van Guilder, G.P.1    Pretorius, M.2    Luther, J.M.3    Byrd, J.B.4    Hill, K.5    Gainer, J.V.6    Brown, N.J.7
  • 83
    • 0037407520 scopus 로고    scopus 로고
    • Extracellular matrix metabolism in diabetic nephropathy
    • DOI 10.1097/01.ASN.0000065640.77499.D7
    • Mason RM, Wahab NA. Extracellular matrix metabolism in diabetic nephropathy. J Am Soc Nephrol 2003; 14: 1358-1373. (Pubitemid 36519197)
    • (2003) Journal of the American Society of Nephrology , vol.14 , Issue.5 , pp. 1358-1373
    • Mason, R.M.1    Wahab, N.A.2
  • 84
    • 48249127629 scopus 로고    scopus 로고
    • From fibrosis to sclerosis: Mechanisms of glomerulosclerosis in diabetic nephropathy
    • Qian Y, Feldman E, Pennathur S et al. From fibrosis to sclerosis: mechanisms of glomerulosclerosis in diabetic nephropathy. Diabetes 2008; 57: 1439-1445.
    • (2008) Diabetes , vol.57 , pp. 1439-1445
    • Qian, Y.1    Feldman, E.2    Pennathur, S.3
  • 86
    • 0028097530 scopus 로고
    • Bradykinin-induced in vitro contraction of rat mesangial cells via a B2 receptor type
    • Bascands JL, Pecher C, Bompart G et al. Bradykinin-induced in vitro contraction of rat mesangial cells via a B2 receptor type. Am J Physiol 1994; 267: F871-F878.
    • (1994) Am J Physiol , vol.267
    • Bascands, J.L.1    Pecher, C.2    Bompart, G.3
  • 87
    • 0037174870 scopus 로고    scopus 로고
    • A novel protein-protein interaction between a G protein-coupled receptor and the phosphatase SHP-2 is involved in bradykinin-induced inhibition of cell proliferation
    • DOI 10.1074/jbc.M202744200
    • Duchene J, Schanstra JP, Pecher C et al. A novel protein-protein interaction between a G protein-coupled receptor and the phosphatase SHP-2 is involved in bradykinin-induced inhibition of cell proliferation. J Biol Chem 2002; 277: 40375-40383. (Pubitemid 35215611)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.43 , pp. 40375-40383
    • Duchene, J.1    Schanstra, J.P.2    Pecher, C.3    Pizard, A.4    Susini, C.5    Esteve, J.-P.6    Bascands, J.-L.7    Girolami, J.-P.8
  • 90
    • 4344603861 scopus 로고    scopus 로고
    • Bradykinin decreases plasminogen activator inhibitor-1 expression and facilitates matrix degradation in the renal tubulointerstitium under angiotensin-converting enzyme blockade
    • DOI 10.1097/01.ASN.0000136132.20189.95
    • Okada H, Watanabe Y, Kikuta T et al. Bradykinin decreases plasminogen activator inhibitor-1 expression and facilitates matrix degradation in the renal tubulointerstitium under angiotensin-converting enzyme blockade. J Am Soc Nephrol 2004; 15: 2404-2413. (Pubitemid 39159340)
    • (2004) Journal of the American Society of Nephrology , vol.15 , Issue.9 , pp. 2404-2413
    • Okada, H.1    Watanabe, Y.2    Kikuta, T.3    Kobayashi, T.4    Kanno, Y.5    Sugaya, T.6    Suzuki, H.7
  • 91
    • 0032734661 scopus 로고    scopus 로고
    • Expression of megsin mRNA, a novel mesangium-predominant gene, in the renal tissues of various glomerular diseases
    • Suzuki D, Miyata T, Nangaku M et al. Expression of megsin mRNA, a novel mesangium-predominant gene, in the renal tissues of various glomerular diseases. J Am Soc Nephrol 1999; 10: 2606-2613.
    • (1999) J Am Soc Nephrol , vol.10 , pp. 2606-2613
    • Suzuki, D.1    Miyata, T.2    Nangaku, M.3
  • 93
    • 58249110409 scopus 로고    scopus 로고
    • Delayed blockade of the kinin B1 receptor reduces renal inflammation and fibrosis in obstructive nephropathy
    • Klein J, Gonzalez J, Duchene J et al. Delayed blockade of the kinin B1 receptor reduces renal inflammation and fibrosis in obstructive nephropathy. FASEB J 2009; 23: 134-142.
    • (2009) FASEB J , vol.23 , pp. 134-142
    • Klein, J.1    Gonzalez, J.2    Duchene, J.3
  • 94
    • 67649352973 scopus 로고    scopus 로고
    • Deletion of bradykinin B1 receptor reduces renal fibrosis
    • Wang PH, Cenedeze MA, Campanholle G et al. Deletion of bradykinin B1 receptor reduces renal fibrosis. Int Immunopharmacol 2009; 9: 653-657.
    • (2009) Int Immunopharmacol , vol.9 , pp. 653-657
    • Wang, P.H.1    Cenedeze, M.A.2    Campanholle, G.3
  • 95
    • 79956019655 scopus 로고    scopus 로고
    • Bradykinin receptor 1 activation exacerbates experimental focal and segmental glomerulosclerosis
    • Pereira RL, Buscariollo BN, Correa-Costa M et al. Bradykinin receptor 1 activation exacerbates experimental focal and segmental glomerulosclerosis. Kidney Int 2011; 79: 1217-1227.
    • (2011) Kidney Int , vol.79 , pp. 1217-1227
    • Pereira, R.L.1    Buscariollo, B.N.2    Correa-Costa, M.3
  • 96
    • 77954603954 scopus 로고    scopus 로고
    • Blockade of the kinin B1 receptor ameliorates glomerulonephritis
    • Klein J, Gonzalez J, Decramer S et al. Blockade of the kinin B1 receptor ameliorates glomerulonephritis. J Am Soc Nephrol 2010; 21: 1157-1164.
    • (2010) J Am Soc Nephrol , vol.21 , pp. 1157-1164
    • Klein, J.1    Gonzalez, J.2    Decramer, S.3
  • 99
    • 0041703027 scopus 로고    scopus 로고
    • Diabetes-induced overexpression of endothelin-1 and endothelin receptors in the rat renal cortex is mediated via poly(ADP-ribose) polymerase activation
    • Minchenko AG, Stevens MJ, White L et al. Diabetes-induced overexpression of endothelin-1 and endothelin receptors in the rat renal cortex is mediated via poly(ADP-ribose) polymerase activation. FASEB J 2003; 17: 1514-1516.
    • (2003) FASEB J , vol.17 , pp. 1514-1516
    • Minchenko, A.G.1    Stevens, M.J.2    White, L.3
  • 100
    • 0028953768 scopus 로고
    • Hepatic expression of mature transforming growth factor beta 1 in transgenic mice results in multiple tissue lesions
    • Sanderson N, Factor V, Nagy P et al. Hepatic expression of mature transforming growth factor beta 1 in transgenic mice results in multiple tissue lesions. Proc Natl Acad Sci USA 1995; 92: 2572-2576.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 2572-2576
    • Sanderson, N.1    Factor, V.2    Nagy, P.3
  • 103
    • 33847069621 scopus 로고    scopus 로고
    • Kinin infusion prevents renal inflammation, apoptosis, and fibrosis via inhibition of oxidative stress and mitogen-activated protein kinase activity
    • Chao J, Li HJ, Yao YY et al. Kinin infusion prevents renal inflammation, apoptosis, and fibrosis via inhibition of oxidative stress and mitogen-activated protein kinase activity. Hypertension 2007; 49: 490-497.
    • (2007) Hypertension , vol.49 , pp. 490-497
    • Chao, J.1    Li, H.J.2    Yao, Y.Y.3
  • 104
    • 0027223728 scopus 로고
    • Reduction of myocardial infarct size in rabbits by ramiprilat: Reversal by the bradykinin antagonist HOE 140
    • Hartman JC, Wall TM, Hullinger TG et al. Reduction of myocardial infarct size in rabbits by ramiprilat: reversal by the bradykinin antagonist HOE 140. J Cardiovasc Pharmacol 1993; 21: 996-1003. (Pubitemid 23160691)
    • (1993) Journal of Cardiovascular Pharmacology , vol.21 , Issue.6 , pp. 996-1003
    • Hartman, J.C.1    Wall, T.M.2    Hullinger, T.G.3    Shebuski, R.J.4
  • 105
    • 0030049292 scopus 로고    scopus 로고
    • Paracrine systems in the cardioprotective effect of angiotensin- converting enzyme inhibitors on myocardial ischemia/reperfusion injury in rats
    • Liu YH, Yang XP, Sharov VG et al. Paracrine systems in the cardioprotective effect of angiotensin-converting enzyme inhibitors on myocardial ischemia/reperfusion injury in rats. Hypertension 1996; 27: 7-13. (Pubitemid 26017674)
    • (1996) Hypertension , vol.27 , Issue.1 , pp. 7-13
    • Liu, Y.-H.1    Yang, X.-P.2    Sharov, V.G.3    Sigmon, D.H.4    Sabbah, H.N.5    Carretero, O.A.6
  • 107
    • 0033534052 scopus 로고    scopus 로고
    • Dilated and failing cardiomyopathy in bradykinin B2 receptor knockout mice
    • Emanueli C, Maestri R, Corradi D et al. Dilated and failing cardiomyopathy in bradykinin B2 receptor knockout mice. Circulation 1999; 100: 2359-2365.
    • (1999) Circulation , vol.100 , pp. 2359-2365
    • Emanueli, C.1    Maestri, R.2    Corradi, D.3
  • 109
    • 77954930286 scopus 로고    scopus 로고
    • Loss of bradykinin signaling does not accelerate the development of cardiac dysfunction in type 1 diabetic Akita mice
    • Wende AR, Soto J, Olsen CD et al. Loss of bradykinin signaling does not accelerate the development of cardiac dysfunction in type 1 diabetic Akita mice. Endocrinology 2010; 151: 3536-3542.
    • (2010) Endocrinology , vol.151 , pp. 3536-3542
    • Wende, A.R.1    Soto, J.2    Olsen, C.D.3
  • 110
    • 0025883342 scopus 로고
    • Nitric oxide: Physiology, pathophysiology, and pharmacology
    • Moncada S, Palmer RM, Higgs EA. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol Rev 1991; 43: 109-142.
    • (1991) Pharmacol Rev , vol.43 , pp. 109-142
    • Moncada, S.1    Palmer, R.M.2    Higgs, E.A.3
  • 111
    • 0032707717 scopus 로고    scopus 로고
    • Nitric oxide as a signaling molecule in the vascular system: An overview
    • Ignarro LJ, Cirino G, Casini A et al. Nitric oxide as a signaling molecule in the vascular system: an overview. J Cardiovasc Pharmacol 1999; 34: 879-886.
    • (1999) J Cardiovasc Pharmacol , vol.34 , pp. 879-886
    • Ignarro, L.J.1    Cirino, G.2    Casini, A.3
  • 112
    • 0032930417 scopus 로고    scopus 로고
    • Mammalian nitric oxide synthases
    • DOI 10.1016/S0005-2728(99)00016-X, PII S000527289900016X
    • Stuehr DJ. Mammalian nitric oxide synthases. Biochim Biophys Acta 1999; 1411: 217-230. (Pubitemid 29221951)
    • (1999) Biochimica et Biophysica Acta - Bioenergetics , vol.1411 , Issue.2-3 , pp. 217-230
    • Stuehr, D.J.1
  • 113
    • 0029983264 scopus 로고    scopus 로고
    • Identification, characterization, and comparison of the calmodulin-binding domains of the endothelial and inducible nitric oxide synthases
    • Venema RC, Sayegh HS, Kent JD et al. Identification, characterization, and comparison of the calmodulin-binding domains of the endothelial and inducible nitric oxide synthases. J Biol Chem 1996; 271: 6435-6440.
    • (1996) J Biol Chem , vol.271 , pp. 6435-6440
    • Venema, R.C.1    Sayegh, H.S.2    Kent, J.D.3
  • 114
    • 0033567065 scopus 로고    scopus 로고
    • Enzymatic function of nitric oxide synthases
    • DOI 10.1016/S0008-6363(99)00115-7, PII S0008636399001157
    • Andrew PJ, Mayer B. Enzymatic function of nitric oxide synthases. Cardiovasc Res 1999; 43: 521-531. (Pubitemid 29369251)
    • (1999) Cardiovascular Research , vol.43 , Issue.3 , pp. 521-531
    • Andrew, P.J.1    Mayer, B.2
  • 115
    • 77049085479 scopus 로고    scopus 로고
    • Differential regulation of inducible and endothelial nitric oxide synthase by kinin B1 and B2 receptors
    • Kuhr F, Lowry J, Zhang Y et al. Differential regulation of inducible and endothelial nitric oxide synthase by kinin B1 and B2 receptors. Neuropeptides 2010; 44: 145-154.
    • (2010) Neuropeptides , vol.44 , pp. 145-154
    • Kuhr, F.1    Lowry, J.2    Zhang, Y.3
  • 116
    • 4644337419 scopus 로고    scopus 로고
    • Putative roles of kinin receptors in the therapeutic effects of angiotensin 1-converting enzyme inhibitors in diabetes mellitus
    • DOI 10.1016/j.ejphar.2004.07.045, PII S001429990400754X
    • Couture R, Girolami JP. Putative roles of kinin receptors in the therapeutic effects of angiotensin 1-converting enzyme inhibitors in diabetes mellitus. Eur J Pharmacol 2004; 500: 467-485. (Pubitemid 39304028)
    • (2004) European Journal of Pharmacology , vol.500 , Issue.1-3 SPEC. ISS. , pp. 467-485
    • Couture, R.1    Girolami, J.-P.2
  • 117
    • 0028840962 scopus 로고
    • Endothelium-dependent relaxations mediated by inducible B1 and constitutive B2 kinin receptors in the bovine isolated coronary artery
    • Drummond GR, Cocks TM. Endothelium-dependent relaxations mediated by inducible B1 and constitutive B2 kinin receptors in the bovine isolated coronary artery. Br J Pharmacol 1995; 116: 2473-2481.
    • (1995) Br J Pharmacol , vol.116 , pp. 2473-2481
    • Drummond, G.R.1    Cocks, T.M.2
  • 119
    • 6944224025 scopus 로고    scopus 로고
    • 1 receptors stimulate nitric oxide production in endothelial cells: Signaling pathways activated by angiotensin I-converting enzyme inhibitors and peptide ligands
    • DOI 10.1124/mol.104.001990
    • Ignjatovic T, Stanisavljevic S, Brovkovych V et al. Kinin B1 receptors stimulate nitric oxide production in endothelial cells: signaling pathways activated by angiotensin I-converting enzyme inhibitors and peptide ligands. Mol Pharmacol 2004; 66: 1310-1316. (Pubitemid 39411071)
    • (2004) Molecular Pharmacology , vol.66 , Issue.5 , pp. 1310-1316
    • Ignjatovic, T.1    Stanisavljevic, S.2    Brovkovych, V.3    Skidgel, R.A.4    Erdos, E.G.5
  • 122
    • 0033917346 scopus 로고    scopus 로고
    • Risk of advanced diabetic nephropathy in type 1 diabetes is associated with endothelial nitric oxide synthase gene polymorphism
    • DOI 10.1046/j.1523-1755.2000.00860.x
    • Zanchi A, Moczulski DK, Hanna LS et al. Risk of advanced diabetic nephropathy in type 1 diabetes is associated with endothelial nitric oxide synthase gene polymorphism. Kidney Int 2000; 57: 405-413. (Pubitemid 30430632)
    • (2000) Kidney International , vol.57 , Issue.2 , pp. 405-413
    • Zanchi, A.1    Moczulski, D.K.2    Hanna, L.S.3    Wantman, M.4    Warram, J.H.5    Krolewski, A.S.6
  • 123
    • 0034007216 scopus 로고    scopus 로고
    • Association of the nitric oxide synthase gene polymorphism with an increased risk for progression to diabetic nephropathy in type 2 diabetes
    • Neugebauer S, Baba T, Watanabe T. Association of the nitric oxide synthase gene polymorphism with an increased risk for progression to diabetic nephropathy in type 2 diabetes. Diabetes 2000; 49: 500-503. (Pubitemid 30131798)
    • (2000) Diabetes , vol.49 , Issue.3 , pp. 500-503
    • Neugebauer, S.1    Baba, T.2    Watanabe, T.3
  • 124
    • 0027674693 scopus 로고
    • L-Arginine administration prevents glomerular hyperfiltration and decreases proteinuria in diabetic rats
    • Reyes AA, Karl IE, Kissane J et al. L-Arginine administration prevents glomerular hyperfiltration and decreases proteinuria in diabetic rats. J Am Soc Nephrol 1993; 4: 1039-1045.
    • (1993) J Am Soc Nephrol , vol.4 , pp. 1039-1045
    • Reyes, A.A.1    Karl, I.E.2    Kissane, J.3
  • 125
    • 33747277744 scopus 로고    scopus 로고
    • Chronic inhibition of nitric oxide production aggravates diabetic nephropathy in Otsuka Long-Evans Tokushima Fatty rats
    • Kamijo H, Higuchi M, Hora K. Chronic inhibition of nitric oxide production aggravates diabetic nephropathy in Otsuka Long-Evans Tokushima Fatty rats. Nephron Physiol 2006; 104: p12-p22.
    • (2006) Nephron Physiol , vol.104 , pp. 12-22
    • Kamijo, H.1    Higuchi, M.2    Hora, K.3
  • 129
    • 79952143828 scopus 로고    scopus 로고
    • A modest decrease in endothelial NOS in mice comparable to that associated with human NOS3 variants exacerbates diabetic nephropathy
    • Wang CH, Li F, Hiller S et al. A modest decrease in endothelial NOS in mice comparable to that associated with human NOS3 variants exacerbates diabetic nephropathy. Proc Natl Acad Sci USA 2011; 108: 2070-2075.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 2070-2075
    • Wang, C.H.1    Li, F.2    Hiller, S.3
  • 131
    • 0032609301 scopus 로고    scopus 로고
    • Role of nitric oxide in the pathogenesis of diabetic nephropathy in streptozotocin-induced diabetic rats
    • Choi KC, Lee SC, Kim SW et al. Role of nitric oxide in the pathogenesis of diabetic nephropathy in streptozotocin-induced diabetic rats. Korean J Intern Med 1999; 14: 32-41.
    • (1999) Korean J Intern Med , vol.14 , pp. 32-41
    • Choi, K.C.1    Lee, S.C.2    Kim, S.W.3
  • 132
    • 0036363163 scopus 로고    scopus 로고
    • Chronic diabetic nephropathy: Role of inducible nitric oxide synthase
    • DOI 10.1007/s004670200004
    • Trachtman H, Futterweit S, Pine E et al. Chronic diabetic nephropathy: role of inducible nitric oxide synthase. Pediatr Nephrol 2002; 17: 20-29. (Pubitemid 41490200)
    • (2002) Pediatric Nephrology , vol.17 , Issue.1 , pp. 20-29
    • Trachtman, H.1    Futterweit, S.2    Pine, E.3    Mann, J.4    Valderrama, E.5
  • 133
    • 76049118200 scopus 로고    scopus 로고
    • Role of oxidative stress in diabetic kidney disease
    • Hakim FA, Pflueger A. Role of oxidative stress in diabetic kidney disease. Med Sci Monit 2010; 16: RA37-RA48.
    • (2010) Med Sci Monit , vol.16
    • Hakim, F.A.1    Pflueger, A.2
  • 134
    • 33748308770 scopus 로고    scopus 로고
    • Diabetic nephropathy is associated with gene expression levels of oxidative phosphorylation and related pathways
    • DOI 10.2337/db05-1438
    • Huang C, Kim Y, Caramori ML et al. Diabetic nephropathy is associated with gene expression levels of oxidative phosphorylation and related pathways. Diabetes 2006; 55: 1826-1831. (Pubitemid 44324139)
    • (2006) Diabetes , vol.55 , Issue.6 , pp. 1826-1831
    • Huang, C.1    Kim, Y.2    Caramori, M.L.3    Moore, J.H.4    Rich, S.S.5    Mychaleckyj, J.C.6    Walker, P.C.7    Mauer, M.8
  • 135
    • 37549035027 scopus 로고    scopus 로고
    • Diabetic nephropathy: Mechanisms of renal disease progression
    • Kanwar YS, Wada J, Sun L et al. Diabetic nephropathy: mechanisms of renal disease progression. Exp Biol Med (Maywood) 2008; 233: 4-11.
    • (2008) Exp Biol Med (Maywood) , vol.233 , pp. 4-11
    • Kanwar, Y.S.1    Wada, J.2    Sun, L.3
  • 137
    • 20044376702 scopus 로고    scopus 로고
    • The pathobiology of diabetic complications: A unifying mechanism
    • DOI 10.2337/diabetes.54.6.1615
    • Brownlee M. The pathobiology of diabetic complications: a unifying mechanism. Diabetes 2005; 54: 1615-1625. (Pubitemid 40770750)
    • (2005) Diabetes , vol.54 , Issue.6 , pp. 1615-1625
    • Brownlee, M.1
  • 138
    • 78349297565 scopus 로고    scopus 로고
    • Oxidative stress and diabetic complications
    • Giacco F, Brownlee M. Oxidative stress and diabetic complications. Circ Res 2010; 107: 1058-1070.
    • (2010) Circ Res , vol.107 , pp. 1058-1070
    • Giacco, F.1    Brownlee, M.2
  • 139
    • 0035461381 scopus 로고    scopus 로고
    • 2+ superoxide dismutase protects against early diabetic glomerular injury in transgenic mice
    • 2+ superoxide dismutase protects against early diabetic glomerular injury in transgenic mice. Diabetes 2001; 50: 2114-2125.
    • (2001) Diabetes , vol.50 , pp. 2114-2125
    • Craven, P.A.1    Melhem, M.F.2    Phillips, S.L.3
  • 140
    • 1442349987 scopus 로고    scopus 로고
    • Attenuation of Renal Injury in db/db Mice Overexpressing Superoxide Dismutase: Evidence for Reduced Superoxide - Nitric Oxide Interaction
    • DOI 10.2337/diabetes.53.3.762
    • DeRubertis FR, Craven PA, Melhem MF et al. Attenuation of renal injury in db/db mice overexpressing superoxide dismutase: evidence for reduced superoxide-nitric oxide interaction. Diabetes 2004; 53: 762-768. (Pubitemid 38270647)
    • (2004) Diabetes , vol.53 , Issue.3 , pp. 762-768
    • DeRubertis, F.R.1    Craven, P.A.2    Melhem, M.F.3    Salah, E.M.4
  • 141
    • 78649755150 scopus 로고    scopus 로고
    • +/-AkitaJ mice by the mitochondria-targeted therapy mitoQ
    • +/-AkitaJ mice by the mitochondria-targeted therapy mitoQ. Biochem J 2010; 432: 9-19.
    • (2010) Biochem J , vol.432 , pp. 9-19
    • Chacko, B.K.1    Reily, C.2    Srivastava, A.3
  • 142
    • 28044464985 scopus 로고
    • Reversible inhibition of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, by nitric oxide
    • DOI 10.1016/0014-5793(94)00424-2
    • Cleeter MW, Cooper JM, Darley-Usmar VM et al. Reversible inhibition of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, by nitric oxide. Implications for neurodegenerative diseases. FEBS Lett 1994; 345: 50-54. (Pubitemid 24154664)
    • (1994) FEBS Letters , vol.345 , Issue.1 , pp. 50-54
    • Cleeter, M.W.J.1    Cooper, A.M.2    Darley-Usmar, B.M.3    Moncada, D.4    Schapira, A.H.V.5
  • 143
    • 0028134892 scopus 로고
    • Nanomolar concentrations of nitric oxide reversibly inhibit synaptosomal respiration by competing with oxygen at cytochrome oxidase
    • DOI 10.1016/0014-5793(94)01290-3
    • Brown GC, Cooper CE. Nanomolar concentrations of nitric oxide reversibly inhibit synaptosomal respiration by competing with oxygen at cytochrome oxidase. FEBS Lett 1994; 356: 295-298. (Pubitemid 24376992)
    • (1994) FEBS Letters , vol.356 , Issue.2-3 , pp. 295-298
    • Brown, G.C.1
  • 144
    • 0027945838 scopus 로고
    • Nitric oxide potently and reversibly deenergizes mitochondria at low oxygen tension
    • DOI 10.1006/bbrc.1994.2441
    • Schweizer M, Richter C. Nitric oxide potently and reversibly deenergizes mitochondria at low oxygen tension. Biochem Biophys Res Commun 1994; 204: 169-175. (Pubitemid 24335277)
    • (1994) Biochemical and Biophysical Research Communications , vol.204 , Issue.1 , pp. 169-175
    • Schweizer, M.1    Richter, C.2
  • 147
    • 59849109480 scopus 로고    scopus 로고
    • Bradykinin protects against oxidative stress-induced endothelial cell senescence
    • Oeseburg H, Iusuf D, van der Harst P et al. Bradykinin protects against oxidative stress-induced endothelial cell senescence. Hypertension 2009; 53: 417-422.
    • (2009) Hypertension , vol.53 , pp. 417-422
    • Oeseburg, H.1    Iusuf, D.2    Van Der Harst, P.3
  • 149
    • 0031081639 scopus 로고    scopus 로고
    • Effects of cicaprost and fosinopril on the progression of rat diabetic nephropathy
    • DOI 10.1016/S0895-7061(96)00319-6, PII S0895706196003196
    • Villa E, Rabano A, Ruilope LM et al. Effects of cicaprost and fosinopril on the progression of rat diabetic nephropathy. Am J Hypertens 1997; 10: 202-208. (Pubitemid 27084632)
    • (1997) American Journal of Hypertension , vol.10 , Issue.2 , pp. 202-208
    • Villa, E.1    Rabano, A.2    Ruilope, L.M.3    Garcia-Robles, R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.