Decreased renal NO excretion and reduced glomerular tuft area in mice lacking the bradykinin B2 receptor

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 284, Issue 6 53-6, 2003, Pages

  Schanstra, Joost P ^a   Duchene, Johan ^a   Praddaude, Françoise ^a   Bruneval, Patrick ^b   Tack, Ivan ^a   Chevalier, Jacques ^b   Girolami, Jean Pierre ^a   Bascands, Jean Loup ^a  

^a CHU RANGUEIL   (France)

^b HÔPITAL BROUSSAIS   (France)

Author keywords

Backcross; Genetic background; Hemodynamics; Kidney; Nitric oxide

Indexed keywords

BRADYKININ B2 RECEPTOR; CYCLIC GMP; NITRIC OXIDE; NITRITE;

ARTICLE; BLOOD PRESSURE; CONTROLLED STUDY; GLOMERULUS; GLOMERULUS FILTRATION RATE; KIDNEY BLOOD FLOW; KIDNEY PLASMA FLOW; KIDNEY VASCULAR RESISTANCE; KNOCKOUT MOUSE; MALE; MORPHOMETRICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEQUENCE ANALYSIS;

EID: 0038362736     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.01150.2002     Document Type: Article

References (32)

1. 2 receptors. Hypertension 29: 483-487, 1997.
2. Beierwaltes WH, Carretero OA, and Scicli AG. Renal hemodynamics in response to a kinin analogue antagonist. Am J Physiol Renal Fluid Electrolyte Physiol 255: F408-F414, 1988.
3. Bhoola KD, Figueroa CD, and Worthy K. Bioregulation of kinins: kallikreins, kininogens, and kininases. Pharmacol Rev 44: 1-80, 1992.
4. 2 bradykinin receptor gene in mice eliminates bradykinin action in smooth muscle and neurons. J Biol Chem 270: 13706-13710, 1995.
5. Brochu I, Labonte J, Bkaily G, and D'Orleans-Juste P. Role of endothelin receptors in the hypertensive state of kinin B(2) knockout mice subjected to a high-salt diet. Clin Sci (Lond) 103, Suppl 48: 380S-384S, 2002.
6. Cervenka L, Harrison-Bernard LM, Dipp S, Primrose G, Imig JD, and El-Dahr SS. Early onset of salt-sensitive hypertension in bradykinin B(2) receptor null mice. Hypertension 34: 176-180, 1999.
7. Cervenka L, Maly J, Karasova L, Simova M, Vitko S, Hellerova S, Heller J, and El-Dahr SS. Angiotensin II-induced hypertension in bradykinin B2 receptor knockout mice. Hypertension 37: 967-973, 2001.
8. Emanueli C, Bonaria Salis M, Figueroa C, Chao J, Chao L, Gaspa L, Capogrossi MC, and Madeddu P. Participation of kinins in the captopril-induced inhibition of intimal hyperplasia caused by interruption of carotid blood flow in the mouse. Br J Pharmacol 130: 1076-1082, 2000.
9. Grider J, Falcone J, Kilpatrick E, Ott C, and Jackson B. Effect of bradykinin on NaCl transport in the medullary thick ascending limb of the rat. Eur J Pharmacol 287: 101-104, 1995.
10. Heudes D, Michel O, Chevalier J, Scalbert E, Ezan E, Bariety J, Zimmerman A, and Corman B. Effect of chronic ANG I-converting enzyme inhibition on aging processes. I. Kidney structure and function. Am J Physiol Regul Integr Comp Physiol 266: R1038-R1051, 1994.
11. Huang W, Gallois Y, Bouby N, Bruneval P, Heudes D, Belair MF, Krege JH, Meneton P, Marre M, Smithies O, and Alhenc-Gelas F. Genetically increased angiotensin I-converting enzyme level and renal complications in the diabetic mouse. Proc Natl Acad Sci USA 98: 13330-13334, 2001.
12. Jaspard E, Wei L, and Alhenc-Gelas F. Differences in the properties and enzymatic specificities of the two active sites of angiotensin I-converting enzyme (kininase II). Studies with bradykinin and other natural peptides. J Biol Chem 268: 9496-9503, 1993.
13. 2-kinin receptors in the renal tubular and hemodynamic response to bradykinin. Am J Physiol Regul Integr Comp Physiol 262: R72-R76, 1992.
14. MacKay K, Striker LJ, Elliot S, Pinkert CA, Brinster RL, and Striker GE. Glomerular epithelial, mesangial, and endothelial cell lines from transgenic mice. Kidney Int 33: 677-684, 1988.
15. Madeddu P, Varoni MV, Palomba D, Emanueli C, Demontis MP, Glorioso N, Dessi-Fulgheri P, Sarzani R, and Anania V. Cardiovascular phenotype of a mouse strain with disruption of bradykinin B2 receptor gene. Circulation 96: 3570-3578, 1997.
16. Marceau F, Hess JF, and Bachvarov DR. The B1 receptors for kinins. Pharmacol Rev 50: 357-386, 1998.
17. Marin-Castano ME, Schanstra JP, Neau E, Praddaude F, Pecher C, Ader JL, Girolami JP, and Bascands JL. Induction of functional bradykinin B(1)-receptors in normotensive rats and mice under chronic angiotensin-converting enzyme inhibitor treatment. Circulation 105: 627-632, 2002.
18. Milia AF, Gross V, Plehm R, De Silva JA Jr, Bader M, and Luft FC. Normal blood pressure and renal function in mice lacking the bradykinin B(2) receptor. Hypertension 37: 1473-1479, 2001.
19. Praddaude F, Tack I, Emond C, Bascands JL, Girolami JP, Tran-Van T, Regoli D, and Ader JL. In vivo and in vitro homologous desensitization of rat glomerular bradykinin B2 receptors. Eur J Pharmacol 294: 173-182, 1995.
20. Regoli D and Barabe J. Pharmacology of bradykinin and related kinins. Pharmacol Rev 32: 1-46, 1980.
21. Schanstra JP, Marin-Castano ME, Praddaude F, Tack I, Ader JL, Girolami JP, and Bascands JL. Bradykinin B(1) receptor-mediated changes in renal hemodynamics during endotoxin-induced inflammation. J Am Soc Nephrol 11: 1208-1215, 2000.
22. Schanstra JP, Neau E, Drogoz P, Arevalo Gomez MA, Lopez Novoa JM, Calise D, Pecher C, Bader M, Girolami JP, and Bascands JL. In vivo bradykinin B2 receptor activation reduces renal fibrosis. J Clin Invest 110: 371-379, 2002.
23. Scicli AG and Carretero OA. Renal kallikrein-kinin system. Kidney Int 29: 120-130, 1986.
24. Margolius HS. Kallikreins and kinins. Some unanswered questions about system characteristics and roles in human disease. Hypertension 26: 221-229, 1995.
25. Sigmund CD. Viewpoint: are studies in genetically altered mice out of control? Arterioscler Thromb Vasc Biol 20: 1425-1429, 2000.
26. Silvestre JS, Bergaya S, Tamarat R, Duriez M, Boulanger CM, and Levy BI. Proangiogenic effect of angiotensin-converting enzyme inhibition is mediated by the bradykinin B(2) receptor pathway. Circ Res 89: 678-683, 2001.
27. Siragy HM. Evidence that intrarenal bradykinin plays a role in regulation of renal function. Am J Physiol Endocrinol Metab 265: E648-E654, 1993.
28. Tack I, Marin-Castano E, Bascands JL, Pecher C, Ader JL, and Girolami JP. Cyclosporine A-induced increase in glomerular cyclic GMP in rats and the involvement of the endothelin B receptor. Br J Pharmacol 121: 433-440, 1997.
29. Trabold F, Pons S, Hagege AA, Bloch-Faure M, Alhenc-Gelas F, Giudicelli JF, Richer-Giudicelli C, and Meneton P. Cardiovascular phenotypes of kinin B2 receptor- and tissue kallikrein-deficient mice. Hypertension 40: 90-95, 2002.
30. Wang D, Yoshida H, Song Q, Chao L, and Chao J. Enhanced renal function in bradykinin B(2) receptor transgenic mice. Am J Physiol Renal Physiol 278: F484-F491, 2000.
31. Yang XP, Liu YH, Scicli GM, Webb CR, and Carretero OA. Role of kinins in the cardioprotective effect of preconditioning: study of myocardial ischemia/reperfusion injury in B2 kinin receptor knockout mice and kininogen-deficient rats. Hypertension 30: 735-740, 1997.
32. Yang XP, Liu YH, Mehta D, Cavasin MA, Shesely E, Xu J, Liu F, and Carretero OA. Diminished cardioprotective response to inhibition of angiotensin-converting enzyme and anqgiotensin II type 1 receptor in B(2) kinin receptor gene knockout mice. Circ Res 88: 1072-1079, 2001.