Deletion of bradykinin B1 receptor reduces renal fibrosis

International Immunopharmacology

Volumn 9, Issue 6, 2009, Pages 653-657

  Wang, Pamella Huey Mei ^a   Cenedeze, Marcos Antonio ^a   Campanholle, Gabriela ^b   Malheiros, Denise Maria Avancini Costa ^b   de Moura Torres, Hugo Arruda ^a   Pesquero, João Bosco ^a   Pacheco Silva, Alvaro ^a   Câmara, Niels Olsen Saraiva ^a,b  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

B1R knockout mice and renal fibrosis; Bradykinin B1 receptor; Kallikein kinin system; Unilateral ureteral obstruction

Indexed keywords

BRADYKININ B1 RECEPTOR; CREATININE; HEME OXYGENASE 1; INTERLEUKIN 10; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CREATININE URINE LEVEL; GENE DELETION; GENE EXPRESSION PROFILING; IMMUNOMODULATION; KALLIKREIN KININ SYSTEM; KIDNEY FIBROSIS; KNOCKOUT MOUSE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEINURIA; RENAL PROTECTION;

ANIMALS; CHEMOKINE CCL2; CREATININE; FIBROSIS; GENE DELETION; HEME OXYGENASE-1; INTERLEUKIN-10; INTERLEUKIN-6; KALLIKREIN-KININ SYSTEM; KIDNEY; KIDNEY DISEASES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PROTEINURIA; RECEPTOR, BRADYKININ B1; TRANSFORMING GROWTH FACTOR BETA; URETERAL OBSTRUCTION;

EID: 67649352973     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2008.10.018     Document Type: Article

References (54)

1. Wynn T.A. Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases. J Clin Invest 117 3 (2007) 524-529
2. Tomasek J.J., Gabbiani G., Hinz B., Chaponnier C., and Brown R.A. Myofibroblasts and mechano-regulation of connective tissue remodelling. Nat Rev Mol Cell Biol 3 5 (2002) 349-363
3. Friedman S.L. Mechanisms of disease: mechanisms of hepatic fibrosis and therapeutic implications. Nat Clin Pract Gastroenterol Hepatol 1 2 (2004) 98-105
4. Klahr S. Obstructive nephropathy. Kidney Int 54 1 (1998) 286-300
5. Klahr S., and Morrissey J.J. The role of growth factors, cytokines, and vasoactive compounds in obstructive nephropathy. Semin Nephrol 18 6 (1998) 622-632
6. Klahr S., and Morrissey J. Angiotensin II and gene expression in the kidney. Am J Kidney Dis 31 1 (1998) 171-176
7. Bascands J.L., and Schanstra J.P. Obstructive nephropathy: insights from genetically engineered animals. Kidney Int 68 3 (2005) 925-937
8. Feldman D.L., Mogelesky T.C., Chou M., and Jeng A.Y. Enhanced expression of renal endothelin-converting enzyme-1 and endothelin-A-receptor mRNA in rats with interstitial fibrosis following ureter ligation. J Cardiovasc Pharmacol 36 5 Suppl 1 (2000) S255-259
9. Fern R.J., Yesko C.M., Thornhill B.A., Kim H.S., Smithies O., and Chevalier R.L. Reduced angiotensinogen expression attenuates renal interstitial fibrosis in obstructive nephropathy in mice. J Clin Invest 103 1 (1999) 39-46
10. Fukuda K., Yoshitomi K., Yanagida T., Tokumoto M., and Hirakata H. Quantification of TGF-beta1 mRNA along rat nephron in obstructive nephropathy. Am J Physiol Renal Physiol 281 3 (2001) F513-521
11. Serlachius E., Svennilson J., Schalling M., and Aperia A. Protein kinase C in the developing kidney: isoform expression and effects of ceramide and PKC inhibitors. Kidney Int 52 4 (1997) 901-910
12. Strutz F., Okada H., Lo C.W., Danoff T., Carone R.L., Tomaszewski J.E., et al. Identification and characterization of a fibroblast marker: FSP1. J Cell Biol 130 2 (1995) 393-405
13. Marceau F., Hess J.F., and Bachvarov D.R. The B1 receptors for kinins. Pharmacol Rev 50 3 (1998) 357-386
14. Schanstra J.P., Bataille E., Marin Castano M.E., Barascud Y., Hirtz C., Pesquero J.B., et al. The B1-agonist [des-Arg10]-kallidin activates transcription factor NF-kappaB and induces homologous upregulation of the bradykinin B1-receptor in cultured human lung fibroblasts. J Clin Invest 101 10 (1998) 2080-2091
15. Schanstra J.P., Neau E., Drogoz P., Arevalo Gomez M.A., Lopez Novoa J.M., Calise D., et al. In vivo bradykinin B2 receptor activation reduces renal fibrosis. J Clin Invest 110 3 (2002) 371-379
16. Zhang Y., Adner M., and Cardell L.O. Glucocorticoids suppress transcriptional up-regulation of bradykinin receptors in a murine in vitro model of chronic airway inflammation. Clin Exp Allergy 35 4 (2005) 531-538
17. Mezzano S.A., Ruiz-Ortega M., and Egido J. Angiotensin II and renal fibrosis. Hypertension 38 3 Pt 2 (2001) 635-638
18. Gaedeke J., Peters H., Noble N.A., and Border W.A. Angiotensin II, TGF-beta and renal fibrosis. Contrib Nephrol 135 (2001) 153-160
19. Rosenkranz S. TGF-beta1 and angiotensin networking in cardiac remodeling. Cardiovasc Res 63 3 (2004) 423-432
20. Ishidoya S., Morrissey J., McCracken R., Reyes A., and Klahr S. Angiotensin II receptor antagonist ameliorates renal tubulointerstitial fibrosis caused by unilateral ureteral obstruction. Kidney Int 47 5 (1995) 1285-1294
21. Ishikawa A., Tanaka M., Ohta N., Ozono S., and Kitamura T. Prevention of interstitial fibrosis of renal allograft by angiotensin II blockade. Transplant Proc 38 10 (2006) 3498-3501
22. Klahr S., and Morrissey J.J. Comparative study of ACE inhibitors and angiotensin II receptor antagonists in interstitial scarring. Kidney Int Suppl 63 (1997) S111-114
23. Campbell D.J., Kladis A., and Duncan A.M. Effects of converting enzyme inhibitors on angiotensin and bradykinin peptides. Hypertension 23 4 (1994) 439-449
24. Schanstra J.P., Duchene J., Desmond L., Neau E., Calise D., Estaque S., et al. The protective effect of angiotensin converting enzyme inhibition in experimental renal fibrosis in mice is not mediated by bradykinin B2 receptor activation. Thromb Haemost 89 4 (2003) 735-740
25. Emanueli C., Bonaria Salis M., Stacca T., Pintus G., Kirchmair R., Isner J.M., et al. Targeting kinin B(1) receptor for therapeutic neovascularization. Circulation 105 3 (2002) 360-366
26. Ni A., Yin H., Agata J., Yang Z., Chao L., and Chao J. Overexpression of kinin B1 receptors induces hypertensive response to des-Arg9-bradykinin and susceptibility to inflammation. J Biol Chem 278 1 (2003) 219-225
27. Liesmaa I., Kuoppala A., Shiota N., Kokkonen J.O., Kostner K., Mayranpaa M., et al. Increased expression of bradykinin type-1 receptors in endothelium of intramyocardial coronary vessels in human failing hearts. Am J Physiol Heart Circ Physiol 288 5 (2005) H2317-2322
28. Dray A., and Perkins M. Bradykinin and inflammatory pain. Trends Neurosci 16 3 (1993) 99-104
29. McLean P.G., Ahluwalia A., and Perretti M. Association between kinin B(1) receptor expression and leukocyte trafficking across mouse mesenteric postcapillary venules. J Exp Med 192 3 (2000) 367-380
30. Perretti M., Appleton I., Parente L., and Flower R.J. Pharmacology of interleukin-1-induced neutrophil migration. Agents Actions 38 (1993) Spec No:C64-5
31. Ahluwalia A., and Perretti M. Calcitonin gene-related peptides modulate the acute inflammatory response induced by interleukin-1 in the mouse. Eur J Pharmacol 264 3 (1994) 407-415
32. Tiffany C.W., and Burch R.M. Bradykinin stimulates tumor necrosis factor and interleukin-1 release from macrophages. FEBS Lett 247 2 (1989) 189-192
33. Sato E., Koyama S., Nomura H., Kubo K., and Sekiguchi M. Bradykinin stimulates alveolar macrophages to release neutrophil, monocyte, and eosinophil chemotactic activity. J Immunol 157 7 (1996) 3122-3129
34. Koyama S., Sato E., Numanami H., Kubo K., Nagai S., and Izumi T. Bradykinin stimulates lung fibroblasts to release neutrophil and monocyte chemotactic activity. Am J Respir Cell Mol Biol 22 1 (2000) 75-84
35. Wang P.H., Cenedeze M.A., Pesquero J.B., Pacheco-Silva A., and Camara N.O. Influence of bradykinin B1 and B2 receptors in the immune response triggered by renal ischemia-reperfusion injury. Int Immunopharmacol 6 13-14 (2006) 1960-1965
36. Isaka Y., Tsujie M., Ando Y., Nakamura H., Kaneda Y., Imai E., et al. Transforming growth factor-beta 1 antisense oligodeoxynucleotides block interstitial fibrosis in unilateral ureteral obstruction. Kidney Int 58 5 (2000) 1885-1892
37. Kaneto H., Ohtani H., Fukuzaki A., Ishidoya S., Takeda A., Ogata Y., et al. Increased expression of TGF-beta1 but not of its receptors contributes to human obstructive nephropathy. Kidney Int 56 6 (1999) 2137-2146
38. Miyajima A., Chen J., Lawrence C., Ledbetter S., Soslow R.A., Stern J., et al. Antibody to transforming growth factor-beta ameliorates tubular apoptosis in unilateral ureteral obstruction. Kidney Int 58 6 (2000) 2301-2313
39. Roberts A.B., Russo A., Felici A., and Flanders K.C. Smad3: a key player in pathogenetic mechanisms dependent on TGF-beta. Ann N Y Acad Sci 995 (2003) 1-10
40. Kuwabara N., Tamada S., Iwai T., Teramoto K., Kaneda N., Yukimura T., et al. Attenuation of renal fibrosis by curcumin in rat obstructive nephropathy. Urology 67 2 (2006) 440-446
41. Taal M.W., Zandi-Nejad K., Weening B., Shahsafaei A., Kato S., Lee K.W., et al. Proinflammatory gene expression and macrophage recruitment in the rat remnant kidney. Kidney Int 58 4 (2000) 1664-1676
42. Klahr S., and Morrissey J. Obstructive nephropathy and renal fibrosis. Am J Physiol Renal Physiol 283 5 (2002) F861-875
43. Diamond J.R., Ricardo S.D., and Klahr S. Mechanisms of interstitial fibrosis in obstructive nephropathy. Semin Nephrol 18 6 (1998) 594-602
44. Crisman J.M., Richards L.L., Valach D.P., Franzoni D.F., and Diamond J.R. Chemokine expression in the obstructed kidney. Exp Nephrol 9 4 (2001) 241-248
45. Hasegawa M., Fujimoto M., Takehara K., and Sato S. Pathogenesis of systemic sclerosis: altered B cell function is the key linking systemic autoimmunity and tissue fibrosis. J Dermatol Sci 39 1 (2005) 1-7
46. Karkar A.M., Smith J., Tam F.W., Pusey C.D., and Rees A.J. Abrogation of glomerular injury in nephrotoxic nephritis by continuous infusion of interleukin-6. Kidney Int 52 5 (1997) 1313-1320
47. Mu W., Ouyang X., Agarwal A., Zhang L., Long D.A., Cruz P.E., et al. IL-10 suppresses chemokines, inflammation, and fibrosis in a model of chronic renal disease. J Am Soc Nephrol 16 12 (2005) 3651-3660
48. Thompson K., Maltby J., Fallowfield J., McAulay M., Millward-Sadler H., and Sheron N. Interleukin-10 expression and function in experimental murine liver inflammation and fibrosis. Hepatology 28 6 (1998) 1597-1606
49. Louis H., Van Laethem J.L., Wu W., Quertinmont E., Degraef C., Van den Berg K., et al. Interleukin-10 controls neutrophilic infiltration, hepatocyte proliferation, and liver fibrosis induced by carbon tetrachloride in mice. Hepatology 28 6 (1998) 1607-1615
50. Demols A., Van Laethem J.L., Quertinmont E., Degraef C., Delhaye M., Geerts A., et al. Endogenous interleukin-10 modulates fibrosis and regeneration in experimental chronic pancreatitis. Am J Physiol Gastrointest Liver Physiol 282 6 (2002) G1105-1112
51. Kim J.H., Yang J.I., Jung M.H., Hwa J.S., Kang K.R., Park D.J., et al. Heme oxygenase-1 protects rat kidney from ureteral obstruction via an antiapoptotic pathway. J Am Soc Nephrol 17 5 (2006) 1373-1381
52. Nakamichi I., Habtezion A., Zhong B., Contag C.H., Butcher E.C., and Omary M.B. Hemin-activated macrophages home to the pancreas and protect from acute pancreatitis via heme oxygenase-1 induction. J Clin Invest 115 11 (2005) 3007-3014
53. Iwai T., Kitamoto K., Teramoto K., Machida Y., Tamada S., Yukimura T., et al. Cobalt protoporphyrin attenuates rat obstructive nephropathy: role of cellular infiltration. Urology 72 2 (2008) 432-438
54. Wang L., Lee J.Y., Kwak J.H., He Y., Kim S.I., and Choi M.E. Protective effects of low-dose carbon monoxide against renal fibrosis induced by unilateral ureteral obstruction. Am J Physiol Renal Physiol 294 3 (2008) F508-517