The B1-agonist [des-Arg10]-kallidin activates transcription factor NF-κB and induces homologous upregulation of the bradykinin B1-receptor in cultured human lung fibroblasts

Journal of Clinical Investigation

Volumn 101, Issue 10, 1998, Pages 2080-2091

  Schanstra, Joost P ^a   Bataillé, Emmanuelle ^b   Marin Castaño, Maria E ^a   Barascud, Yannick ^a   Hirtz, Christophe ^a   Pesquero, João B ^c,d   Pecher, Christiane ^a   Gauthier, Francis ^b   Girolami, Jean Pierre ^a   Bascands, Jean Loup ^a  

^a CHU RANGUEIL   (France)

^b UNIVERSITÉ DE TOURS   (France)

^c MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^d FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

B1 receptor; Bradykinin; Gene expression; Inflammation; NF B

Indexed keywords

2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; BRADYKININ; BRADYKININ B1 RECEPTOR; BRADYKININ B1 RECEPTOR AGONIST; CALCIUM; CHOLERA TOXIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; KALLIDIN; PERTUSSIS TOXIN; PHORBOL ESTER; PROTEIN KINASE C; PYRROLIDINE DITHIOCARBAMATE; TRANSCRIPTION FACTOR; BORDETELLA VIRULENCE FACTOR; BRADYKININ RECEPTOR; BRADYKININ, LYS LEU(8) DESARG(9); BRADYKININ, LYS-LEU(8)-DESARG(9)-; DNA BINDING PROTEIN; DRUG DERIVATIVE; INTERLEUKIN 1; KALLIDIN, DES ARG(10); KALLIDIN, DES-ARG(10)-; MESSENGER RNA; PROLINE; PROLINEDITHIOCARBAMATE; PYRROLIDINE DERIVATIVE; PYRROLIDINE DITHIOCARBAMIC ACID; THIOCARBAMIC ACID DERIVATIVE;

AMINO ACID SEQUENCE; ARTICLE; CALCIUM CELL LEVEL; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; HUMAN; HUMAN CELL; INFLAMMATION; LUNG FIBROBLAST; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PROTEIN INTERACTION; RECEPTOR BLOCKING; RECEPTOR UPREGULATION; STRUCTURE ACTIVITY RELATION; TRANSCRIPTION REGULATION; CELL LINE; DRUG EFFECT; DRUG POTENTIATION; FIBROBLAST; LUNG; METABOLISM; MOLECULAR GENETICS; PATHOPHYSIOLOGY; TRANSACTIVATION; UPREGULATION;

AMINO ACID SEQUENCE; CELL LINE; CHOLERA TOXIN; DNA-BINDING PROTEINS; FIBROBLASTS; HUMANS; INFLAMMATION; INTERLEUKIN-1; KALLIDIN; LUNG; MOLECULAR SEQUENCE DATA; NF-KAPPA B; PROLINE; PYRROLIDINES; RECEPTOR, BRADYKININ B1; RECEPTORS, BRADYKININ; RNA, MESSENGER; THIOCARBAMATES; TRANS-ACTIVATION (GENETICS); UP-REGULATION; VIRULENCE FACTORS, BORDETELLA;

EID: 0032523244     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI1359     Document Type: Article

References (57)

1. Regoli, D., and J. Barabe. 1980. Pharmacology of bradykinin and related kinins. Pharmacol. Rev. 32:1-46.
2. Bhoola, K.D., C.D. Figueroa, and K. Worthy. 1992. Bioregulation of kinins: kallikreins, kininogens and kininases. Pharmacol. Rev. 44:1-80.
3. 1 bradykinin receptor. J. Biol. Chem. 269:21583-21586.
4. 1-receptor. Biochim. Biophys. Acta. 1264:223-228.
5. 1-receptor gene. Biochem. Biophys. Res. Commun. 220:219-225.
6. 2 bradykinin receptor. Proc. Natl. Acad. Sci. USA. 88:7724-7728.
7. Hess, J.F., J.A. Borkowski, G.S. Young, C.D. Strader, and R.W. Ransom. 1992. Cloning and pharmacological characterization of a human bradykinin (BK-2) receptor. Biochem. Biophys. Res. Commun. 184:260-268.
8. 2 pharmacological selectivity. Mol. Pharmacol. 44:346-355.
9. 2-kinin-binding sites in two-kidney, one-clip hypersensitive rats. Am. J. Physiol. 260:F626-F634.
10. Trippmer, S., U. Quitterer, V. Kolm, A. Faussner, A. Roscher, L. Mosthaf, W. Müller-Esterl, and H. Häring. 1994. Bradykinin induces translocation of the protein kinase C isoforms α, ∈ and ζ. Eur. J. Biochem. 229:297-304.
11. 2-receptor is a delayed early response gene for platelet-derived growth factor. J. Biol. Chem. 271:13324-13332.
12. 1-receptors: a review. Immunopharmacology. 30:1-26.
13. Margolius, H.S. 1995. Kallikreins and kinins: some unanswered questions about system characteristics and roles in human disease. Hypertension (Dallas). 26:221-229.
14. Hall, J.M. 1992. Bradykinin receptors: pharmacological properties and biological roles. Pharmacol Ther. 56:131-190.
15. Burch, R.M., D.J. Kyle, and T.M. Stormann. 1993. Molecular Biology and Pharmacology of Bradykinin Receptors. CRC Press, Inc., Boca Raton, FL. 107 pp.
16. Farmer, S.G. 1994. The pharmacology of bradykinin in human airways. In Drugs and the Lung. C.P. Page and W.J. Metzger, editors. Raven Press, Ltd., New York. 449-465.
17. Christiansen, S.C., D. Proud, R. Sarnoff, U. Juergens, C.G. Cochrane, and B.L. Zuraw. 1992. Elevation of tissue kallikrein activity in the airways of asthmatic subjects following endobronchial allergen challenge. Am. Rev. Respir. Dis. 145:900-905.
18. Abraham, W.M. 1992. The potential role of bradykinin antagonists in the treatment of asthma. Agents Actions. 439-449.
19. 9]bradykinin in normal and asthmatic subjects. Am. Rev. Respir. Dis. 142:1367-1371.
20. 9]bradykinin in asthmatic subjects. Eur. Respir. J. 6:687-693.
21. Pan, Z.K., B.L. Zuraw, C.C. Lung, E.R. Prossnitz, D.D. Browning, and R.D. Ye. 1996. Bradykinin stimulates NF-κB activation and interleukin 1β gene expression in cultured human fibroblasts. J. Clin. Invest. 98:2042-2049.
22. Barnes, P.J., and I.M. Adcock. 1997. NF-κB: a pivotal role in asthma and a new target for therapy. TIPS (Trends. Pharmacol. Sci.). 18:46-50.
23. 1-receptor in Chinese hamster ovary cells. J. Biol. Chem. 272:11420-11425.
24. Stewart, J.M. 1995. Bradykinin antagonists: development and applications. Biopolymers. 37:143-155.
25. Persson, B., and P. Argos. 1994. Prediction of transmembrane segments in proteins utilising multiple sequence alignments. J. Mol. Biol. 237:182-192.
26. Engelman, D.M., T.T. Steitz, and A. Goldman. 1986. Identifying nonpolar transbilayer helices in amino-acid sequences of membrane proteins. Annu. Rev. Biophys. Biophys. Chem. 15:321-353.
27. Atherton, E., and R.C. Sheppard. 1989. Solid Phase Peptide Synthesis: A Practical Approach. IRL Press at Oxford University, Oxford, United Kingdom. 194 pp.
28. Wong, S.S. 1991. Chemistry of Protein Conjugation and Cross-linking. CRC Press, Inc., Boca Raton, FL. 147-194.
29. Lalmanach, G., J. Hoebeke, T. Moreau, M. Ferrer-Di Martino, and F. Gauthier. 1992. An immunochemical approach to investigating the mechanism of inhibition of cysteine proteinases by members of the cystatin superfamily. J. Immunol. Methods. 149:197-205.
30. Sambrook, J., E.F. Fritsch, and T. Maniatis. 1989. Molecular Cloning: A Laboratory Manual, 2nd Ed. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY. 7.71-7.78.
31. Chomczynski, P., and N. Sacchi. 1987. Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156-159.
32. Bascands, J.-L., C. Pecher, S. Rouaud, C. Emond, J.L. Tack, M.J. Bastie, R. Burch, D. Regoli, and J.-P. Girolami. 1993. Evidence for the existence of two distinct bradykinin receptors on rat mesangial cells. Am. J. Physiol. 264:F548-F556.
33. 2+ indicators with greatly improved fluorescence properties. J. Biol. Chem. 260:3440-3450.
34. Dignam, J.D., R.M. Lebovitz, and R.G.R. Roeder. 1983. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11:1475-1489.
35. 1-receptor gene for kinins (BDKRB1). Genomics. 33:374-381.
36. Blank, V., P. Kourilsky, and A. Israël. 1992. NF-κB and related proteins: Rel/dorsal homologies meet ankyrin-like repeats. TIPS (Trends. Pharmacol. Sci.). 17:135-140.
37. Thanos, D., and T. Maniatis. 1995. NF-κB: a lesson in family values. Cell. 80:529-532.
38. Dinarello, C.A. 1994. The interleukin-1 family: 10 years of discovery. FASEB J. 8:1314-1325.
39. Schreck, R., and P. Baeuerle. 1991. A role for oxygen radicals as second messengers. Trends Cell. Biol. 1:39-42.
40. Baeuerle, P.A., and D. Baltimore. 1996. NF-κB: ten years after. Cell. 87: 13-20.
41. 2-receptor involved in ligand binding and agonist sensing defined by anti-peptide antibodies. J. Biol. Chem. 271:1748-1755.
42. 2-receptor amino terminus. Biochemistry. 35:7514-7519.
43. Thomas, R.F., B.D. Holt, D.A. Schwinn, and S.B. Liggett. 1992. Longterm agonist exposure induces up-regulation of beta 3-adrenergic receptor expression via multiple cAMP response elements. Proc. Natl. Acad. Sci. USA. 89: 4490-4494.
44. Starr, S., L.B. Kozell, and K.A. Neve. 1995. Drug-induced up-regulation of dopamine D2 receptors on cultured cells. J. Neurochem. 65:569-577.
45. Cheng, H.F., B.N. Becker, K.D. Burns, and R.C. Harris. 1995. Angiotensin II upregulates type-1 angiotensin II receptors in renal proximal tubule. J. Clin. Invest. 95:2012-2019.
46. q. Science. 251:804-807.
47. - and G-protein βγ-subunit-regulated phospholipase C-activating protein. J. Biol. Chem. 266:14217-14225.
48. 11α. J. Biol. Chem. 268:14367-14375.
49. q class of G proteins. Nature. 350:516-518.
50. Ghosh, S., and D. Baltimore. 1990. Activation in vitro of NF-κB by phosphorylation of its inhibitor. Nature. 344:678-682.
51. Rice, C.L., J.P. Kohker, L. Casey, J.P. Szidon, M. Daise, and G.S. Moss. 1983. Angiotensin-converting enzyme (ACE) in sepsis. Circ. Shock. 11:59-63.
52. 9-bradykinin. J. Biol. Chem. 259:9263-9268.
53. Hollinger, M.A. 1983. Effect of endotoxin on mouse serum angiotensin-converting enzyme. Am. Rev. Respir. Dis. 1276:756-757.
54. Nukiwa, T., R. Matsuoka, H. Takagi, Y. Ishii, T. Arai, and S. Kira. 1982. Responses of serum and lung angiotensin-converting enzyme activities in the early phase of pulmonary damage induced by oleic acid in dogs. Am. Rev. Respir. Dis. 126:1080-1086.
55. 1) receptors in vivo. Eur. J. Pharmacol. 160:125-132.
56. 2-receptors. Eur. J. Pharmacol. 294: 173-182.
57. 2 agonist activity. J. Med. Chem. 37:348-355.