메뉴 건너뛰기




Volumn 60, Issue 2, 2012, Pages 139-151

Differential Expression of the Glutamate Transporter GLT-1 in Pancreas

Author keywords

EAAT2; GLT1; Glutamine Synthetase; SLC1a2

Indexed keywords

EXCITATORY AMINO ACID TRANSPORTER 2; GLUTAMATE AMMONIA LIGASE; MEMBRANE PROTEIN; PROTEIN GLUTAMATE UPTAKE TRANSPORTER 1A; PROTEIN GLUTAMATE UPTAKE TRANSPORTER 1B; PROTEIN GLUTAMATE UPTAKE TRANSPORTER 1C; PROTEIN VARIANT; UNCLASSIFIED DRUG; SLC1A2 PROTEIN, MOUSE;

EID: 84859237382     PISSN: 00221554     EISSN: None     Source Type: Journal    
DOI: 10.1369/0022155411430095     Document Type: Article
Times cited : (13)

References (66)
  • 1
    • 29444459269 scopus 로고    scopus 로고
    • Neuronal glutathione deficiency and age-dependent neurodegeneration in the EAAC1 deficient mouse
    • Aoyama K,Suh SW,Hamby AM,Liu J,Chan WY,Chen Y,Swanson RA.Neuronal glutathione deficiency and age-dependent neurodegeneration in the EAAC1 deficient mouse.Nat Neurosci. 2006;9:119-126.
    • (2006) Nat Neurosci , vol.9 , pp. 119-126
    • Aoyama, K.1    Suh, S.W.2    Hamby, A.M.3    Liu, J.4    Chan, W.Y.5    Chen, Y.6    Swanson, R.A.7
  • 4
    • 33845370329 scopus 로고    scopus 로고
    • Distribution of the glutamate transporters GLT-1 (SLC1A2) and GLAST (SLC1A3) in peripheral organs
    • Berger UV,Hediger MA.Distribution of the glutamate transporters GLT-1 (SLC1A2) and GLAST (SLC1A3) in peripheral organs.Anat Embryol (Berl). 2006;211:595-606.
    • (2006) Anat Embryol (Berl) , vol.211 , pp. 595-606
    • Berger, U.V.1    Hediger, M.A.2
  • 6
    • 0036096430 scopus 로고    scopus 로고
    • Glutamate transporters in hyperammonemia
    • Butterworth RF.Glutamate transporters in hyperammonemia.Neurochem Int. 2002;41:81-85.
    • (2002) Neurochem Int , vol.41 , pp. 81-85
    • Butterworth, R.F.1
  • 9
    • 0032702799 scopus 로고    scopus 로고
    • Evidence for an astrocytic glutamate transporter deficit in hepatic encephalopathy
    • Chan H,Butterworth RF.Evidence for an astrocytic glutamate transporter deficit in hepatic encephalopathy.Neurochem Res. 1999;24:1397-1401.
    • (1999) Neurochem Res , vol.24 , pp. 1397-1401
    • Chan, H.1    Butterworth, R.F.2
  • 10
    • 0037088930 scopus 로고    scopus 로고
    • Expression of a variant form of the glutamate transporter GLT1 in neuronal cultures and in neurons and astrocytes in the rat brain
    • Chen W,Aoki C,Mahadomrongkul V,Gruber CE,Wang GJ,Blitzblau R,Irwin N,Rosenberg PA.Expression of a variant form of the glutamate transporter GLT1 in neuronal cultures and in neurons and astrocytes in the rat brain.J Neurosci. 2002;22:2142-2152.
    • (2002) J Neurosci , vol.22 , pp. 2142-2152
    • Chen, W.1    Aoki, C.2    Mahadomrongkul, V.3    Gruber, C.E.4    Wang, G.J.5    Blitzblau, R.6    Irwin, N.7    Rosenberg, P.A.8
  • 12
    • 13744264524 scopus 로고
    • The high affinity uptake system for excitatory amino acids in the brain
    • Danbolt NC.The high affinity uptake system for excitatory amino acids in the brain.Prog Neurobiol. 1994;44:377-396.
    • (1994) Prog Neurobiol , vol.44 , pp. 377-396
    • Danbolt, N.C.1
  • 13
    • 0035001341 scopus 로고    scopus 로고
    • Glutamate uptake
    • Danbolt NC.Glutamate uptake.Prog Neurobiol. 2001;65:1-105.
    • (2001) Prog Neurobiol , vol.65 , pp. 1-105
    • Danbolt, N.C.1
  • 15
    • 0036209793 scopus 로고    scopus 로고
    • A broad view of glutamate spillover
    • Diamond JS.A broad view of glutamate spillover.Nat Neurosci. 2002;5:291-292.
    • (2002) Nat Neurosci , vol.5 , pp. 291-292
    • Diamond, J.S.1
  • 16
    • 35948996601 scopus 로고    scopus 로고
    • Nutrient control of insulin secretion in perifused adult pig islets
    • Dufrane D,Nenquin M,Henquin JC.Nutrient control of insulin secretion in perifused adult pig islets.Diabetes Metab. 2007;33:430-438.
    • (2007) Diabetes Metab , vol.33 , pp. 430-438
    • Dufrane, D.1    Nenquin, M.2    Henquin, J.C.3
  • 19
    • 54549086447 scopus 로고    scopus 로고
    • A quantitative assessment of glutamate uptake into hippocampal synaptic terminals and astrocytes: New insights into a neuronal role for excitatory amino acid transporter 2 (EAAT2)
    • Furness DN,Dehnes Y,Akhtar AQ,Rossi DJ,Hamann M,Grutle NJ,Gundersen V,Holmseth S,Lehre KP,Ullensvang K, et al.A quantitative assessment of glutamate uptake into hippocampal synaptic terminals and astrocytes: New insights into a neuronal role for excitatory amino acid transporter 2 (EAAT2).Neuroscience. 2008;157:80-94.
    • (2008) Neuroscience , vol.157 , pp. 80-94
    • Furness, D.N.1    Dehnes, Y.2    Akhtar, A.Q.3    Rossi, D.J.4    Hamann, M.5    Grutle, N.J.6    Gundersen, V.7    Holmseth, S.8    Lehre, K.P.9    Ullensvang, K.10
  • 20
    • 77957777297 scopus 로고    scopus 로고
    • Exon-skipping splice variants of excitatory amino acid transporter-2 (EAAT2) form heteromeric complexes with full-length EAAT2
    • Gebhardt FM,Mitrovic AD,Gilbert DF,Vandenberg RJ,Lynch JW,Dodd PR.Exon-skipping splice variants of excitatory amino acid transporter-2 (EAAT2) form heteromeric complexes with full-length EAAT2.J Biol Chem. 2010;285:31313-31324.
    • (2010) J Biol Chem , vol.285 , pp. 31313-31324
    • Gebhardt, F.M.1    Mitrovic, A.D.2    Gilbert, D.F.3    Vandenberg, R.J.4    Lynch, J.W.5    Dodd, P.R.6
  • 21
    • 33947139689 scopus 로고    scopus 로고
    • Hepatocellular expression of glutamine synthetase: an indicator of morphogen actions as master regulators of zonation in adult liver. Prog Histochem Cytochem
    • Gebhardt R,Baldysiak-Figiel A,Krugel V,Ueberham E,Gaunitz F.Hepatocellular expression of glutamine synthetase: an indicator of morphogen actions as master regulators of zonation in adult liver. Prog Histochem Cytochem. 2007;41:201-266.
    • (2007) , vol.41 , pp. 201-266
    • Gebhardt, R.1    Baldysiak-Figiel, A.2    Krugel, V.3    Ueberham, E.4    Gaunitz, F.5
  • 24
    • 34249792922 scopus 로고    scopus 로고
    • Glutamine metabolism and signaling in the liver
    • Haussinger D,Schliess F.Glutamine metabolism and signaling in the liver.Front Biosci. 2007;12:371-391.
    • (2007) Front Biosci , vol.12 , pp. 371-391
    • Haussinger, D.1    Schliess, F.2
  • 25
    • 33845541249 scopus 로고    scopus 로고
    • Nutrient control of insulin secretion in isolated normal human islets
    • Henquin JC,Dufrane D,Nenquin M.Nutrient control of insulin secretion in isolated normal human islets.Diabetes. 2006;55:3470-3477.
    • (2006) Diabetes , vol.55 , pp. 3470-3477
    • Henquin, J.C.1    Dufrane, D.2    Nenquin, M.3
  • 26
    • 26944466760 scopus 로고    scopus 로고
    • Decreased metabolic response to visual stimulation in the superior colliculus of mice lacking the glial glutamate transporter GLT-1
    • Herard AS,Dubois A,Escartin C,Tanaka K,Delzescaux T,Hantraye P,Bonvento G.Decreased metabolic response to visual stimulation in the superior colliculus of mice lacking the glial glutamate transporter GLT-1.Eur J Neurosci. 2005;22:1807-1811.
    • (2005) Eur J Neurosci , vol.22 , pp. 1807-1811
    • Herard, A.S.1    Dubois, A.2    Escartin, C.3    Tanaka, K.4    Delzescaux, T.5    Hantraye, P.6    Bonvento, G.7
  • 27
    • 28844479374 scopus 로고    scopus 로고
    • Specificity of antibodies: unexpected cross-reactivity of antibodies directed against the excitatory amino acid transporter 3 (EAAT3)
    • Holmseth S,Dehnes Y,Bjornsen LP,Boulland JL,Furness DN,Bergles D,Danbolt NC.Specificity of antibodies: unexpected cross-reactivity of antibodies directed against the excitatory amino acid transporter 3 (EAAT3).Neuroscience. 2005;136:649-660.
    • (2005) Neuroscience , vol.136 , pp. 649-660
    • Holmseth, S.1    Dehnes, Y.2    Bjornsen, L.P.3    Boulland, J.L.4    Furness, D.N.5    Bergles, D.6    Danbolt, N.C.7
  • 28
    • 67949091098 scopus 로고    scopus 로고
    • The concentrations and distributions of three C-terminal variants of the GLT1 (EAAT2; slc1a2) glutamate transporter protein in rat brain tissue suggest differential regulation
    • Holmseth S,Scott HA,Real K,Lehre KP,Leergaard TB,Bjaalie JG,Danbolt NC.The concentrations and distributions of three C-terminal variants of the GLT1 (EAAT2; slc1a2) glutamate transporter protein in rat brain tissue suggest differential regulation.Neuroscience. 2009;162:1055-1071.
    • (2009) Neuroscience , vol.162 , pp. 1055-1071
    • Holmseth, S.1    Scott, H.A.2    Real, K.3    Lehre, K.P.4    Leergaard, T.B.5    Bjaalie, J.G.6    Danbolt, N.C.7
  • 29
    • 0034711151 scopus 로고    scopus 로고
    • Glutamate transporter EAAT2 splice variants occur not only in ALS, but also in AD and controls
    • Honig LS,Chambliss DD,Bigio EH,Carroll SL,Elliott JL.Glutamate transporter EAAT2 splice variants occur not only in ALS, but also in AD and controls.Neurology. 2000;55:1082-1088.
    • (2000) Neurology , vol.55 , pp. 1082-1088
    • Honig, L.S.1    Chambliss, D.D.2    Bigio, E.H.3    Carroll, S.L.4    Elliott, J.L.5
  • 30
    • 0035350443 scopus 로고    scopus 로고
    • Molecular identification of high-affinity glutamate transporters in sheep and cattle forestomach, intestine, liver, kidney, and pancreas
    • Howell JA,Matthews AD,Swanson KC,Harmon DL,Matthews JC.Molecular identification of high-affinity glutamate transporters in sheep and cattle forestomach, intestine, liver, kidney, and pancreas.J Anim Sci. 2001;79:1329-1336.
    • (2001) J Anim Sci , vol.79 , pp. 1329-1336
    • Howell, J.A.1    Matthews, A.D.2    Swanson, K.C.3    Harmon, D.L.4    Matthews, J.C.5
  • 31
    • 0842301342 scopus 로고    scopus 로고
    • Climbing fiber activation of EAAT4 transporters and kainate receptors in cerebellar Purkinje cells
    • Huang YH,Dykes-Hoberg M,Tanaka K,Rothstein JD,Bergles DE.Climbing fiber activation of EAAT4 transporters and kainate receptors in cerebellar Purkinje cells.J Neurosci. 2004;24:103-111.
    • (2004) J Neurosci , vol.24 , pp. 103-111
    • Huang, Y.H.1    Dykes-Hoberg, M.2    Tanaka, K.3    Rothstein, J.D.4    Bergles, D.E.5
  • 32
    • 0036942123 scopus 로고    scopus 로고
    • Distinct distribution of laminin and its integrin receptors in the pancreas
    • Jiang FX,Naselli G,Harrison LC.Distinct distribution of laminin and its integrin receptors in the pancreas.J Histochem Cytochem. 2002;50:1625-1632.
    • (2002) J Histochem Cytochem , vol.50 , pp. 1625-1632
    • Jiang, F.X.1    Naselli, G.2    Harrison, L.C.3
  • 33
    • 0141655189 scopus 로고    scopus 로고
    • Cloning and characterization of the 3'-untranslated region of the human excitatory amino acid transporter 2 transcript
    • Kim SY,Chao W,Choi SY,Volsky DJ.Cloning and characterization of the 3'-untranslated region of the human excitatory amino acid transporter 2 transcript.J Neurochem. 2003;86:1458-1467.
    • (2003) J Neurochem , vol.86 , pp. 1458-1467
    • Kim, S.Y.1    Chao, W.2    Choi, S.Y.3    Volsky, D.J.4
  • 34
    • 0029098659 scopus 로고
    • Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95
    • Kornau HC,Schenker LT,Kennedy MB,Seeburg PH.Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95.Science. 1995;269:1737-1740.
    • (1995) Science , vol.269 , pp. 1737-1740
    • Kornau, H.C.1    Schenker, L.T.2    Kennedy, M.B.3    Seeburg, P.H.4
  • 35
    • 0032194950 scopus 로고    scopus 로고
    • The number of glutamate transporter subtype molecules at glutamatergic synapses: chemical and stereological quantification in young adult rat brain
    • Lehre KP,Danbolt NC.The number of glutamate transporter subtype molecules at glutamatergic synapses: chemical and stereological quantification in young adult rat brain.J Neurosci. 1998;18:8751-8757.
    • (1998) J Neurosci , vol.18 , pp. 8751-8757
    • Lehre, K.P.1    Danbolt, N.C.2
  • 36
    • 0032400828 scopus 로고    scopus 로고
    • Stoichiometry of the glial glutamate transporter GLT-1 expressed inducibly in a Chinese hamster ovary cell line selected for low endogenous Na+-dependent glutamate uptake
    • Levy LM,Warr O,Attwell D.Stoichiometry of the glial glutamate transporter GLT-1 expressed inducibly in a Chinese hamster ovary cell line selected for low endogenous Na+-dependent glutamate uptake.J Neurosci. 1998;18:9620-9628.
    • (1998) J Neurosci , vol.18 , pp. 9620-9628
    • Levy, L.M.1    Warr, O.2    Attwell, D.3
  • 37
    • 33645847822 scopus 로고    scopus 로고
    • Regulation of astrocytic glutamate transporter expression by Akt: evidence for a selective transcriptional effect on the GLT-1/EAAT2 subtype
    • Li LB,Toan SV,Zelenaia O,Watson DJ,Wolfe JH,Rothstein JD,Robinson MB.Regulation of astrocytic glutamate transporter expression by Akt: evidence for a selective transcriptional effect on the GLT-1/EAAT2 subtype.J Neurochem. 2006;97:759-771.
    • (2006) J Neurochem , vol.97 , pp. 759-771
    • Li, L.B.1    Toan, S.V.2    Zelenaia, O.3    Watson, D.J.4    Wolfe, J.H.5    Rothstein, J.D.6    Robinson, M.B.7
  • 39
    • 0032032013 scopus 로고    scopus 로고
    • Aberrant RNA processing in a neurodegenerative disease: the cause for absent EAAT2, a glutamate transporter, in amyotrophic lateral sclerosis
    • Lin C-LG,Bristol LA,Jin L,Dykes-Hoberg M,Crawford T,Clawson L,Rothstein JD.Aberrant RNA processing in a neurodegenerative disease: the cause for absent EAAT2, a glutamate transporter, in amyotrophic lateral sclerosis.Neuron. 1998;20:589-602.
    • (1998) Neuron , vol.20 , pp. 589-602
    • Lin, C.-L.G.1    Bristol, L.A.2    Jin, L.3    Dykes-Hoberg, M.4    Crawford, T.5    Clawson, L.6    Rothstein, J.D.7
  • 42
    • 0030976929 scopus 로고    scopus 로고
    • Glutamate transporter EAAC-1-deficient mice develop dicarboxylic aminoaciduria and behavioral abnormalities but no neurodegeneration
    • Peghini P,Janzen J,Stoffel W.Glutamate transporter EAAC-1-deficient mice develop dicarboxylic aminoaciduria and behavioral abnormalities but no neurodegeneration.EMBO J. 1997;16:3822-3832.
    • (1997) EMBO J , vol.16 , pp. 3822-3832
    • Peghini, P.1    Janzen, J.2    Stoffel, W.3
  • 43
    • 45249086342 scopus 로고    scopus 로고
    • Coupling of neural activity to blood flow in olfactory glomeruli is mediated by astrocytic pathways
    • Petzold GC,Albeanu DF,Sato TF,Murthy VN.Coupling of neural activity to blood flow in olfactory glomeruli is mediated by astrocytic pathways.Neuron. 2008;58:897-910.
    • (2008) Neuron , vol.58 , pp. 897-910
    • Petzold, G.C.1    Albeanu, D.F.2    Sato, T.F.3    Murthy, V.N.4
  • 45
    • 55549111238 scopus 로고    scopus 로고
    • Substrates and non-transportable analogues induce structural rearrangements at the extracellular entrance of the glial glutamate transporter GLT-1/EAAT2
    • Qu S,Kanner BI.Substrates and non-transportable analogues induce structural rearrangements at the extracellular entrance of the glial glutamate transporter GLT-1/EAAT2.J Biol Chem. 2008;283:26391-26400.
    • (2008) J Biol Chem , vol.283 , pp. 26391-26400
    • Qu, S.1    Kanner, B.I.2
  • 47
    • 0037435395 scopus 로고    scopus 로고
    • Assumption-free analysis of quantitative real-time polymerase chain reaction (PCR) data
    • Ramakers C,Ruijter JM,Deprez RH,Moorman AF.Assumption-free analysis of quantitative real-time polymerase chain reaction (PCR) data.Neurosci Lett. 2003;339:62-66.
    • (2003) Neurosci Lett , vol.339 , pp. 62-66
    • Ramakers, C.1    Ruijter, J.M.2    Deprez, R.H.3    Moorman, A.F.4
  • 48
    • 4444301113 scopus 로고    scopus 로고
    • A new GLT1 splice variant: cloning and immunolocalization of GLT1c in the mammalian retina and brain
    • Rauen T,Wiessner M,Sullivan R,Lee A,Pow DV.A new GLT1 splice variant: cloning and immunolocalization of GLT1c in the mammalian retina and brain.Neurochem Int. 2004;45:1095-1106.
    • (2004) Neurochem Int , vol.45 , pp. 1095-1106
    • Rauen, T.1    Wiessner, M.2    Sullivan, R.3    Lee, A.4    Pow, D.V.5
  • 49
    • 72449164409 scopus 로고    scopus 로고
    • Transport mechanism of a bacterial homologue of glutamate transporters
    • Reyes N,Ginter C,Boudker O.Transport mechanism of a bacterial homologue of glutamate transporters.Nature. 2009;462:880-885.
    • (2009) Nature , vol.462 , pp. 880-885
    • Reyes, N.1    Ginter, C.2    Boudker, O.3
  • 50
    • 44949231424 scopus 로고    scopus 로고
    • Analyzing real-time PCR data by the comparative C(T) method
    • Schmittgen TD,Livak KJ.Analyzing real-time PCR data by the comparative C(T) method.Nat Protoc. 2008;3:1101-1108.
    • (2008) Nat Protoc , vol.3 , pp. 1101-1108
    • Schmittgen, T.D.1    Livak, K.J.2
  • 52
    • 1842585550 scopus 로고    scopus 로고
    • Characterization of novel L-threo-beta-benzyloxyaspartate derivatives, potent blockers of the glutamate transporters
    • Shimamoto K,Sakai R,Takaoka K,Yumoto N,Nakajima T,Amara SG,Shigeri Y.Characterization of novel L-threo-beta-benzyloxyaspartate derivatives, potent blockers of the glutamate transporters.Mol Pharmacol. 2004;65:1008-1015.
    • (2004) Mol Pharmacol , vol.65 , pp. 1008-1015
    • Shimamoto, K.1    Sakai, R.2    Takaoka, K.3    Yumoto, N.4    Nakajima, T.5    Amara, S.G.6    Shigeri, Y.7
  • 53
    • 0036829584 scopus 로고    scopus 로고
    • Regulation of AMPA receptors during synaptic plasticity
    • Song I,Huganir RL.Regulation of AMPA receptors during synaptic plasticity.Trends Neurosci. 2002;25:578-588.
    • (2002) Trends Neurosci , vol.25 , pp. 578-588
    • Song, I.1    Huganir, R.L.2
  • 54
    • 1042279664 scopus 로고    scopus 로고
    • Cloning, transport properties, and differential localization of two splice variants of GLT-1 in the rat CNS: implications for CNS glutamate homeostasis
    • Sullivan R,Rauen T,Fischer F,Wiessner M,Grewer C,Bicho A,Pow DV.Cloning, transport properties, and differential localization of two splice variants of GLT-1 in the rat CNS: implications for CNS glutamate homeostasis.Glia. 2004;45:155-169.
    • (2004) Glia , vol.45 , pp. 155-169
    • Sullivan, R.1    Rauen, T.2    Fischer, F.3    Wiessner, M.4    Grewer, C.5    Bicho, A.6    Pow, D.V.7
  • 57
    • 36348975209 scopus 로고    scopus 로고
    • Glutamate transporters: confining runaway excitation by shaping synaptic transmission
    • Tzingounis AV,Wadiche JI.Glutamate transporters: confining runaway excitation by shaping synaptic transmission.Nat Rev Neurosci. 2007;8:935-947.
    • (2007) Nat Rev Neurosci , vol.8 , pp. 935-947
    • Tzingounis, A.V.1    Wadiche, J.I.2
  • 58
    • 0030716859 scopus 로고    scopus 로고
    • Tissue specific variants of glutamate transporter GLT-1
    • Utsunomiya-Tate N,Endou H,Kanai Y.Tissue specific variants of glutamate transporter GLT-1.FEBS Lett. 1997;416:312-316.
    • (1997) FEBS Lett , vol.416 , pp. 312-316
    • Utsunomiya-Tate, N.1    Endou, H.2    Kanai, Y.3
  • 64
    • 7244254186 scopus 로고    scopus 로고
    • Structure of a glutamate transporter homologue from Pyrococcus horikoshii
    • Yernool D,Boudker O,Jin Y,Gouaux E.Structure of a glutamate transporter homologue from Pyrococcus horikoshii.Nature. 2004;431:811-818.
    • (2004) Nature , vol.431 , pp. 811-818
    • Yernool, D.1    Boudker, O.2    Jin, Y.3    Gouaux, E.4
  • 65
    • 0029860263 scopus 로고    scopus 로고
    • Flux coupling in a neuronal glutamate transporter
    • Zerangue N,Kavanaugh MP.Flux coupling in a neuronal glutamate transporter.Nature. 1996;383:634-637.
    • (1996) Nature , vol.383 , pp. 634-637
    • Zerangue, N.1    Kavanaugh, M.P.2
  • 66
    • 0346888682 scopus 로고    scopus 로고
    • Regulation of glial metabolism studied by 13C-NMR
    • Zwingmann C,Leibfritz D.Regulation of glial metabolism studied by 13C-NMR.NMR Biomed. 2003;16:370-399.
    • (2003) NMR Biomed , vol.16 , pp. 370-399
    • Zwingmann, C.1    Leibfritz, D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.