-
1
-
-
33644655886
-
The number of people with glaucoma worldwide in 2010 and 2020
-
Quigley HA, Broman AT. The number of people with glaucoma worldwide in 2010 and 2020. Br. J. Ophthalmol. 90(3), 262-267 (2006).
-
(2006)
Br. J. Ophthalmol.
, vol.90
, Issue.3
, pp. 262-267
-
-
Quigley, H.A.1
Broman, A.T.2
-
2
-
-
0031800831
-
Mechanical stretch alters the actin cytoskeletal network and signal transduction in human trabecular meshwork cells
-
Tumminia SJ, Mitton KP, Arora J, Zelenka P, Epstein DL, Russell P. Mechanical stretch alters the actin cytoskeletal network and signal transduction in human trabecular meshwork cells. Invest. Ophthalmol. Vis. Sci. 39(8), 1361-1371 (1998).
-
(1998)
Invest. Ophthalmol. Vis. Sci.
, vol.39
, Issue.8
, pp. 1361-1371
-
-
Tumminia, S.J.1
Mitton, K.P.2
Arora, J.3
Zelenka, P.4
Epstein, D.L.5
Russell, P.6
-
3
-
-
33751201214
-
Actin structure in the outflow tract of normal and glaucomatous eyes
-
Read AT, Chan DW, Ethier CR. Actin structure in the outflow tract of normal and glaucomatous eyes. Exp. Eye Res. 84(1), 214-226 (2007).
-
(2007)
Exp. Eye Res.
, vol.84
, Issue.1
, pp. 214-226
-
-
Read, A.T.1
Chan, D.W.2
Ethier, C.R.3
-
4
-
-
64249129112
-
The role of the actomyosin system in regulating trabecular fluid outflow
-
Tian B, Gabelt BT, Geiger B, Kaufman PL. The role of the actomyosin system in regulating trabecular fluid outflow. Exp. Eye Res. 88(4), 713-717 (2009).
-
(2009)
Exp. Eye Res.
, vol.88
, Issue.4
, pp. 713-717
-
-
Tian, B.1
Gabelt, B.T.2
Geiger, B.3
Kaufman, P.L.4
-
6
-
-
0029553517
-
Molecular interactions in the submembrane plaque of cell-cell and cell-matrix adhesions
-
Geiger B, Yehuda-Levenberg S, Bershadsky AD. Molecular interactions in the submembrane plaque of cell-cell and cell-matrix adhesions. Acta Anat. (Basel) 154(1), 46-62 (1995).
-
(1995)
Acta Anat. (Basel
, vol.154
, Issue.1
, pp. 46-62
-
-
Geiger, B.1
Yehuda-Levenberg, S.2
Bershadsky, A.D.3
-
7
-
-
34347255709
-
Dynamics of actin filaments during tension-dependent formation of actin bundles
-
Hirata H, Tatsumi H, Sokabe M. Dynamics of actin filaments during tension-dependent formation of actin bundles. Biochim. Biophys. Acta 1770(8), 1115-1127 (2007).
-
(2007)
Biochim. Biophys. Acta
, vol.1770
, Issue.8
, pp. 1115-1127
-
-
Hirata, H.1
Tatsumi, H.2
Sokabe, M.3
-
8
-
-
77951919561
-
Adherens junctions connect stress fibres between adjacent endothelial cells
-
Millán J, Cain RJ, Reglero-Real N et al. Adherens junctions connect stress fibres between adjacent endothelial cells. BMC Biol. 8, 11 (2010).
-
(2010)
BMC Biol.
, vol.8
, pp. 11
-
-
Millán, J.1
Cain, R.J.2
Reglero-Real, N.3
-
9
-
-
77952935294
-
Adherens junctions remain dynamic
-
Falk MM. Adherens junctions remain dynamic. BMC Biol. 8, 34 (2010).
-
(2010)
BMC Biol.
, vol.8
, pp. 34
-
-
Falk, M.M.1
-
10
-
-
77953075667
-
The chemistry and biology of cytochalasans
-
Scherlach K, Boettger D, Remme N, Hertweck C. The chemistry and biology of cytochalasans. Nat. Prod. Rep. 27(6), 869-886 (2010).
-
(2010)
Nat. Prod. Rep.
, vol.27
, Issue.6
, pp. 869-886
-
-
Scherlach, K.1
Boettger, D.2
Remme, N.3
Hertweck, C.4
-
11
-
-
0024360298
-
Latrunculins - novel marine macrolides that disrupt microfilament organization and affect cell growth: I comparison with cytochalasin D
-
Spector I, Shochet NR, Blasberger D, Kashman Y. Latrunculins - novel marine macrolides that disrupt microfilament organization and affect cell growth: I. Comparison with cytochalasin D. Cell Motil. Cytoskeleton 13(3), 127-144 (1989).
-
(1989)
Cell Motil. Cytoskeleton
, vol.13
, Issue.3
, pp. 127-144
-
-
Spector, I.1
Shochet, N.R.2
Blasberger, D.3
Kashman, Y.4
-
12
-
-
34250211463
-
Influence of actin cytoskeletal integrity on matrix metalloproteinase-2 activation in cultured human trabecular meshwork cells
-
Sanka K, Maddala R, Epstein DL, Rao PV. Influence of actin cytoskeletal integrity on matrix metalloproteinase-2 activation in cultured human trabecular meshwork cells. Invest. Ophthalmol. Vis. Sci. 48(5), 2105-2114 (2007).
-
(2007)
Invest. Ophthalmol. Vis. Sci.
, vol.48
, Issue.5
, pp. 2105-2114
-
-
Sanka, K.1
Maddala, R.2
Epstein, D.L.3
Rao, P.V.4
-
13
-
-
0034725487
-
Effect of latrunculin-A on morphology and actin-associated adhesions of cultured human trabecular meshwork cells
-
Cai S, Liu X, Glasser A et al. Effect of latrunculin-A on morphology and actin-associated adhesions of cultured human trabecular meshwork cells. Mol. Vis. 6, 132-143 (2000).
-
(2000)
Mol. Vis.
, vol.6
, pp. 132-143
-
-
Cai, S.1
Liu, X.2
Glasser, A.3
-
14
-
-
78751705159
-
The effect of biophysical attributes of the ocular trabecular meshwork associated with glaucoma on the cell response to therapeutic agents
-
McKee CT, Wood JA, Shah NM et al. The effect of biophysical attributes of the ocular trabecular meshwork associated with glaucoma on the cell response to therapeutic agents. Biomaterials 32(9), 2417-2423 (2011).
-
(2011)
Biomaterials
, vol.32
, Issue.9
, pp. 2417-2423
-
-
McKee, C.T.1
Wood, J.A.2
Shah, N.M.3
-
15
-
-
0028967310
-
Swinholide A is a microfilament disrupting marine toxin that stabilizes actin dimers and severs actin filaments
-
Bubb MR, Spector I, Bershadsky AD, Korn ED. Swinholide A is a microfilament disrupting marine toxin that stabilizes actin dimers and severs actin filaments. J. Biol. Chem. 270(8), 3463-3466 (1995).
-
(1995)
J. Biol. Chem.
, vol.270
, Issue.8
, pp. 3463-3466
-
-
Bubb, M.R.1
Spector, I.2
Bershadsky, A.D.3
Korn, E.D.4
-
16
-
-
0030993004
-
Autoregulation of actin synthesis responds to monomeric actin levels
-
Lyubimova A, Bershadsky AD, Ben-Ze'ev A. Autoregulation of actin synthesis responds to monomeric actin levels. J. Cell. Biochem. 65(4), 469-478 (1997).
-
(1997)
J. Cell. Biochem.
, vol.65
, Issue.4
, pp. 469-478
-
-
Lyubimova, A.1
Bershadsky, A.D.2
Ben-Ze'ev, A.3
-
17
-
-
0033199069
-
Actin polymerization stimulated by contractile activation regulates force development in canine tracheal smooth muscle
-
Pt 3
-
Mehta D, Gunst SJ. Actin polymerization stimulated by contractile activation regulates force development in canine tracheal smooth muscle. J. Physiol. 19(Pt 3), 829-840 (1999).
-
(1999)
J. Physiol.
, vol.19
, pp. 829-840
-
-
Mehta, D.1
Gunst, S.J.2
-
18
-
-
1842290401
-
Effect of diuretics, channel modulators and signal interceptors on contractility of the trabecular meshwork
-
Wiederholt M, Dörschner N, Groth J. Effect of diuretics, channel modulators and signal interceptors on contractility of the trabecular meshwork. Ophthalmologica 211(3), 153-160 (1997).
-
(1997)
Ophthalmologica
, vol.211
, Issue.3
, pp. 153-160
-
-
Wiederholt, M.1
Dörschner, N.2
Groth, J.3
-
19
-
-
0033010194
-
Latrunculin-A causes mydriasis and cycloplegia in the cynomolgus monkey
-
Peterson JA, Tian B, Geiger B, Kaufman PL. Latrunculin-A causes mydriasis and cycloplegia in the cynomolgus monkey. Invest. Ophthalmol. Vis. Sci. 40(3), 631-638 (1999).
-
(1999)
Invest. Ophthalmol. Vis. Sci.
, vol.40
, Issue.3
, pp. 631-638
-
-
Peterson, J.A.1
Tian, B.2
Geiger, B.3
Kaufman, P.L.4
-
20
-
-
0037227358
-
Inhibitors of actin filament polymerisation attenuate force but not global intracellular calcium in isolated pressurised resistance arteries
-
Shaw L, Ahmed S, Austin C, Taggart MJ. Inhibitors of actin filament polymerisation attenuate force but not global intracellular calcium in isolated pressurised resistance arteries. J. Vasc. Res. 40(1), 1-10 (2003).
-
(2003)
J. Vasc. Res.
, vol.40
, Issue.1
, pp. 1-10
-
-
Shaw, L.1
Ahmed, S.2
Austin, C.3
Taggart, M.J.4
-
21
-
-
0032742546
-
2+ sensitization through inhibition of myosin phosphatase in rabbit trachea
-
2+ sensitization through inhibition of myosin phosphatase in rabbit trachea. Br. J. Pharmacol. 128(4), 925-933 (1999).
-
(1999)
Br. J. Pharmacol.
, vol.128
, Issue.4
, pp. 925-933
-
-
Iizuka, K.1
Yoshii, A.2
Samizo, K.3
-
22
-
-
0042074094
-
Calciumdependent and calcium-independent contractions in smooth muscles
-
Harnett KM, Biancani P. Calciumdependent and calcium-independent contractions in smooth muscles. Am. J. Med. 115(Suppl. 3A), 24S-30S (2003).
-
(2003)
Am. J. Med.
, vol.115
, Issue.SUPPL.3A
-
-
Harnett, K.M.1
Biancani, P.2
-
23
-
-
0027971015
-
Effect of protein kinase inhibitor H-7 on the contractility, integrity, and membrane anchorage of the microfilament system
-
Volberg T, Geiger B, Citi S, Bershadsky AD. Effect of protein kinase inhibitor H-7 on the contractility, integrity, and membrane anchorage of the microfilament system. Cell Motil. Cytoskeleton 29(4), 321-338 (1994).
-
(1994)
Cell Motil. Cytoskeleton
, vol.29
, Issue.4
, pp. 321-338
-
-
Volberg, T.1
Geiger, B.2
Citi, S.3
Bershadsky, A.D.4
-
24
-
-
0031708970
-
H-7 disrupts the actin cytoskeleton and increases outflow facility
-
Tian B, Kaufman PL, Volberg T, Gabelt BT, Geiger B. H-7 disrupts the actin cytoskeleton and increases outflow facility. Arch. Ophthalmol. 116(5), 633-643 (1998).
-
(1998)
Arch. Ophthalmol.
, vol.116
, Issue.5
, pp. 633-643
-
-
Tian, B.1
Kaufman, P.L.2
Volberg, T.3
Gabelt, B.T.4
Geiger, B.5
-
25
-
-
0035789876
-
Effect of H-7 on cultured human trabecular meshwork cells
-
Liu X, Cai S, Glasser A et al. Effect of H-7 on cultured human trabecular meshwork cells. Mol. Vis. 7, 145-153 (2001).
-
(2001)
Mol. Vis.
, vol.7
, pp. 145-153
-
-
Liu, X.1
Cai, S.2
Glasser, A.3
-
26
-
-
0030656619
-
Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension
-
Uehata M, Ishizaki T, Satoh H et al. Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension. Nature 389(6654), 990-994 (1997).
-
(1997)
Nature
, vol.389
, Issue.6654
, pp. 990-994
-
-
Uehata, M.1
Ishizaki, T.2
Satoh, H.3
-
27
-
-
0035972212
-
Rho-kinasemediated contraction of isolated stress fibers
-
Katoh K, Kano Y, Amano M, Onishi H, Kaibuchi K, Fujiwara K. Rho-kinasemediated contraction of isolated stress fibers. J. Cell Biol. 153(3), 569-584 (2001).
-
(2001)
J. Cell Biol.
, vol.153
, Issue.3
, pp. 569-584
-
-
Katoh, K.1
Kano, Y.2
Amano, M.3
Onishi, H.4
Kaibuchi, K.5
Fujiwara, K.6
-
28
-
-
17744397579
-
Contribution of ROCK in contraction of trabecular meshwork: Proposed mechanism for regulating aqueous outflow in monkey and human eyes
-
Nakajima E, Nakajima T, Minagawa Y, Shearer TR, Azuma M. Contribution of ROCK in contraction of trabecular meshwork: proposed mechanism for regulating aqueous outflow in monkey and human eyes. J. Pharm. Sci. 94(4), 701-708 (2005).
-
(2005)
J. Pharm. Sci.
, vol.94
, Issue.4
, pp. 701-708
-
-
Nakajima, E.1
Nakajima, T.2
Minagawa, Y.3
Shearer, T.R.4
Azuma, M.5
-
29
-
-
20444431240
-
Effects of ML-7 and Y-27632 on carbachol- and endothelin-1-induced contraction of bovine trabecular meshwork
-
Rosenthal R, Choritz L, Schlott S et al. Effects of ML-7 and Y-27632 on carbachol- and endothelin-1-induced contraction of bovine trabecular meshwork. Exp. Eye Res. 80(6), 837-845 (2005).
-
(2005)
Exp. Eye Res.
, vol.80
, Issue.6
, pp. 837-845
-
-
Rosenthal, R.1
Choritz, L.2
Schlott, S.3
-
30
-
-
0035164065
-
Effects of Rho-associated protein kinase inhibitor Y-27632 on intraocular pressure and outflow facility
-
Honjo M, Tanihara H, Inatani M et al. Effects of Rho-associated protein kinase inhibitor Y-27632 on intraocular pressure and outflow facility. Invest. Ophthalmol. Vis. Sci. 42(1), 137-144 (2001).
-
(2001)
Invest. Ophthalmol. Vis. Sci.
, vol.42
, Issue.1
, pp. 137-144
-
-
Honjo, M.1
Tanihara, H.2
Inatani, M.3
-
31
-
-
0035066006
-
Modulation of aqueous humor outflow facility by the Rho kinase-specific inhibitor Y-27632
-
Rao PV, Deng PF, Kumar J, Epstein DL. Modulation of aqueous humor outflow facility by the Rho kinase-specific inhibitor Y-27632. Invest. Ophthalmol. Vis. Sci. 42(5), 1029-1037 (2001).
-
(2001)
Invest. Ophthalmol. Vis. Sci.
, vol.42
, Issue.5
, pp. 1029-1037
-
-
Rao, P.V.1
Deng, P.F.2
Kumar, J.3
Epstein, D.L.4
-
32
-
-
12744252830
-
Regulation of myosin light chain phosphorylation in the trabecular meshwork: Role in aqueous humour outflow facility
-
Rao PV, Deng P, Sasaki Y, Epstein DL. Regulation of myosin light chain phosphorylation in the trabecular meshwork: role in aqueous humour outflow facility. Exp. Eye Res. 80(2), 197-206 (2005).
-
(2005)
Exp. Eye Res.
, vol.80
, Issue.2
, pp. 197-206
-
-
Rao, P.V.1
Deng, P.2
Sasaki, Y.3
Epstein, D.L.4
-
35
-
-
66249136738
-
Rho-kinase-mediated suppression of KDR current in cerebral arteries requires an intact actin cytoskeleton
-
Luykenaar KD, El-Rahman RA, Walsh MP, Welsh DG. Rho-kinase-mediated suppression of KDR current in cerebral arteries requires an intact actin cytoskeleton. Am. J. Physiol. Heart Circ. Physiol. 296(4), H917-H926 (2009).
-
(2009)
Am. J. Physiol. Heart Circ. Physiol.
, vol.296
, Issue.4
-
-
Luykenaar, K.D.1
El-Rahman, R.A.2
Walsh, M.P.3
Welsh, D.G.4
-
36
-
-
57349186040
-
Novel molecular insights into RhoA GTPase-induced resistance to aqueous humor outflow through the trabecular meshwork
-
Zhang M, Maddala R, Rao PV. Novel molecular insights into RhoA GTPase-induced resistance to aqueous humor outflow through the trabecular meshwork. Am. J. Physiol. Cell Physiol. 295(5), C1057-C1070 (2008)
-
(2008)
Am. J. Physiol. Cell Physiol.
, vol.295
, Issue.5
-
-
Zhang, M.1
Maddala, R.2
Rao, P.V.3
-
37
-
-
77749254700
-
Mechanistic basis of Rho GTPase-induced extracellular matrix synthesis in trabecular meshwork cells
-
Pattabiraman PP, Rao PV. Mechanistic basis of Rho GTPase-induced extracellular matrix synthesis in trabecular meshwork cells. Am. J. Physiol. Cell Physiol. 298(3), C749-C763 (2010).
-
(2010)
Am. J. Physiol. Cell Physiol.
, vol.298
, Issue.3
-
-
Pattabiraman, P.P.1
Rao, P.V.2
-
38
-
-
64249083219
-
The changing paradigm of outflow resistance generation: Towards synergistic models of the JCT and inner wall endothelium
-
Overby DR, Stamer WD, Johnson M. The changing paradigm of outflow resistance generation: towards synergistic models of the JCT and inner wall endothelium. Exp. Eye Res. 88(4), 656-670 (2009).
-
(2009)
Exp. Eye Res.
, vol.88
, Issue.4
, pp. 656-670
-
-
Overby, D.R.1
Stamer, W.D.2
Johnson, M.3
-
39
-
-
64249131959
-
The trabecular meshwork outflow pathways: Structural and functional aspects
-
Tamm ER. The trabecular meshwork outflow pathways: structural and functional aspects. Exp. Eye Res. 88(4), 648-655 (2009).
-
(2009)
Exp. Eye Res.
, vol.88
, Issue.4
, pp. 648-655
-
-
Tamm, E.R.1
-
40
-
-
0020431955
-
Cytochalasin B and D dose-outflow facility response relationships in the cynomolgus monkey
-
Kaufman PL, Erickson KA. Cytochalasin B and D dose-outflow facility response relationships in the cynomolgus monkey. Invest. Ophthalmol. Vis. Sci. 23(5), 646-650 (1982).
-
(1982)
Invest. Ophthalmol. Vis. Sci.
, vol.23
, Issue.5
, pp. 646-650
-
-
Kaufman, P.L.1
Erickson, K.A.2
-
41
-
-
0033845469
-
Effect of latrunculin-B on outflow facility in monkeys
-
Peterson JA, Tian B, Geiger B, Kaufman PL. Effect of latrunculin-B on outflow facility in monkeys. Exp. Eye Res. 70(3), 307-313 (2000).
-
(2000)
Exp. Eye Res.
, vol.70
, Issue.3
, pp. 307-313
-
-
Peterson, J.A.1
Tian, B.2
Geiger, B.3
Kaufman, P.L.4
-
42
-
-
0034042738
-
Latrunculins' effects on intraocular pressure, aqueous humor flow, and corneal endothelium
-
Peterson JA, Tian B, McLaren JW, Hubbard WC, Geiger B, Kaufman PL. Latrunculins' effects on intraocular pressure, aqueous humor flow, and corneal endothelium. Invest. Ophthalmol. Vis. Sci. 41(7), 1749-1758 (2000).
-
(2000)
Invest. Ophthalmol. Vis. Sci.
, vol.41
, Issue.7
, pp. 1749-1758
-
-
Peterson, J.A.1
Tian, B.2
McLaren, J.W.3
Hubbard, W.C.4
Geiger, B.5
Kaufman, P.L.6
-
43
-
-
5044235080
-
Effect of low-dose latrunculin B on anterior segment physiologic features in the monkey eye
-
Okka M, Tian B, Kaufman PL. Effect of low-dose latrunculin B on anterior segment physiologic features in the monkey eye. Arch. Ophthalmol. 122(10), 1482-1488 (2004).
-
(2004)
Arch. Ophthalmol.
, vol.122
, Issue.10
, pp. 1482-1488
-
-
Okka, M.1
Tian, B.2
Kaufman, P.L.3
-
44
-
-
33744765827
-
Effects of latrunculin-B on outflow facility and trabecular meshwork structure in human eyes
-
Ethier CR, Read AT, Chan DW. Effects of latrunculin-B on outflow facility and trabecular meshwork structure in human eyes. Invest. Ophthalmol. Vis. Sci. 47(5), 1991-1998 (2006).
-
(2006)
Invest. Ophthalmol. Vis. Sci.
, vol.47
, Issue.5
, pp. 1991-1998
-
-
Ethier, C.R.1
Read, A.T.2
Chan, D.W.3
-
45
-
-
79958807531
-
Novel ocular antihypertensive compounds in clinical trials
-
Chen J, Runyan SA, Robinson MR. Novel ocular antihypertensive compounds in clinical trials. Clin. Ophthalmol. 5, 667-677 (2011).
-
(2011)
Clin. Ophthalmol.
, vol.5
, pp. 667-677
-
-
Chen, J.1
Runyan, S.A.2
Robinson, M.R.3
-
46
-
-
3543074115
-
Effects of topical H-7 on outflow facility, intraocular pressure, and corneal thickness in monkeys
-
Tian B, Wang RF, Podos SM, Kaufman PL. Effects of topical H-7 on outflow facility, intraocular pressure, and corneal thickness in monkeys. Arch. Ophthalmol. 122(8), 1171-1177 (2004).
-
(2004)
Arch. Ophthalmol.
, vol.122
, Issue.8
, pp. 1171-1177
-
-
Tian, B.1
Wang, R.F.2
Podos, S.M.3
Kaufman, P.L.4
-
47
-
-
0032930967
-
H-7 increases trabecularfacility and facility after ciliary muscle disinsertion in monkeys
-
Tian B, Gabelt BT, Peterson JA, Kiland JA, Kaufman PL. H-7 increases trabecularfacility and facility after ciliary muscle disinsertion in monkeys. Invest. Ophthalmol. Vis. Sci. 40(1), 239-242 (1999).
-
(1999)
Invest. Ophthalmol. Vis. Sci.
, vol.40
, Issue.1
, pp. 239-242
-
-
Tian, B.1
Gabelt, B.T.2
Peterson, J.A.3
Kiland, J.A.4
Kaufman, P.L.5
-
48
-
-
3142651360
-
Pharmacologic disruption of Schlemm's canal cells and outflow facility in anterior segments of human eyes
-
Bahler CK, Hann CR, Fautsch MP, Johnson DH. Pharmacologic disruption of Schlemm's canal cells and outflow facility in anterior segments of human eyes. Invest. Ophthalmol. Vis. Sci. 45(7), 2246-2254 (2004).
-
(2004)
Invest. Ophthalmol. Vis. Sci.
, vol.45
, Issue.7
, pp. 2246-2254
-
-
Bahler, C.K.1
Hann, C.R.2
Fautsch, M.P.3
Johnson, D.H.4
-
49
-
-
33646196705
-
Monkey organ-cultured anterior segments: Technique and response to H-7
-
Hu Y, Gabelt BT, Kaufman PL. Monkey organ-cultured anterior segments: technique and response to H-7. Exp. Eye Res. 82(6), 1100-1108 (2006).
-
(2006)
Exp. Eye Res.
, vol.82
, Issue.6
, pp. 1100-1108
-
-
Hu, Y.1
Gabelt, B.T.2
Kaufman, P.L.3
-
50
-
-
0034905717
-
Effects of protein kinase inhibitor, HA1077, on intraocular pressure and outflow facility in rabbit eyes
-
Honjo M, Inatani M, Kido N et al. Effects of protein kinase inhibitor, HA1077, on intraocular pressure and outflow facility in rabbit eyes. Arch. Ophthalmol. 119(8), 1171-1178 (2001).
-
(2001)
Arch. Ophthalmol.
, vol.119
, Issue.8
, pp. 1171-1178
-
-
Honjo, M.1
Inatani, M.2
Kido, N.3
-
51
-
-
34548073671
-
Effects of topical administration of y-39983, a selective Rho-associated protein kinase inhibitor, on ocular tissues in rabbits and monkeys
-
Tokushige H, Inatani M, Nemoto S et al. Effects of topical administration of y-39983, a selective Rho-associated protein kinase inhibitor, on ocular tissues in rabbits and monkeys. Invest. Ophthalmol. Vis. Sci. 48(7), 3216-3222 (2007).
-
(2007)
Invest. Ophthalmol. Vis. Sci.
, vol.48
, Issue.7
, pp. 3216-3222
-
-
Tokushige, H.1
Inatani, M.2
Nemoto, S.3
-
52
-
-
12744277365
-
Effects of the Rho kinase inhibitor Y-27632 and the phosphatase inhibitor calyculin A on outflow facility in monkeys
-
Tian B, Kaufman PL. Effects of the Rho kinase inhibitor Y-27632 and the phosphatase inhibitor calyculin A on outflow facility in monkeys. Exp. Eye Res. 80(2), 215-225 (2005).
-
(2005)
Exp. Eye Res.
, vol.80
, Issue.2
, pp. 215-225
-
-
Tian, B.1
Kaufman, P.L.2
-
53
-
-
64249171972
-
Topical administration of a novel and potent Rho kinase (ROK) inhibitor INS117548 alters the actin cytoskeleton, effectively lowers IOP, and is well tolerated on the ocular surface
-
E-abstract 3816
-
Peterson WM, Lampe J, Navratil T et al. Topical administration of a novel and potent Rho kinase (ROK) inhibitor INS117548 alters the actin cytoskeleton, effectively lowers IOP, and is well tolerated on the ocular surface. Invest. Ophthalmol. Vis. Sci. 49, E-abstract 3816 (2008).
-
(2008)
Invest. Ophthalmol. Vis. Sci.
, vol.49
-
-
Peterson, W.M.1
Lampe, J.2
Navratil, T.3
-
54
-
-
40849130917
-
Intraocular pressure-lowering effects and safety of topical administration of a selective ROCK inhibitor, SNJ-1656, in healthy volunteers
-
Tanihara H, Inatani M, Honjo M, Tokushige H, Azuma J, Araie M. Intraocular pressure-lowering effects and safety of topical administration of a selective ROCK inhibitor, SNJ-1656, in healthy volunteers. Arch. Ophthalmol. 126(3), 309-315 (2008).
-
(2008)
Arch. Ophthalmol.
, vol.126
, Issue.3
, pp. 309-315
-
-
Tanihara, H.1
Inatani, M.2
Honjo, M.3
Tokushige, H.4
Azuma, J.5
Araie, M.6
-
55
-
-
80054998108
-
AR-12286 phase 2a study group Ocular hypertensive effect of the Rho kinase inhibitor AR-12286 in patients with glaucoma and ocular hypertension
-
Williams RD, Novack GD, van Haarlem T, Kopczynski C. AR-12286 Phase 2a Study Group. Ocular hypertensive effect of the Rho kinase inhibitor AR-12286 in patients with glaucoma and ocular hypertension. Am. J. Ophthalmol. 152(5), 834-841 (2011).
-
(2011)
Am. J. Ophthalmol.
, vol.152
, Issue.5
, pp. 834-841
-
-
Williams, R.D.1
Novack, G.D.2
Van Haarlem, T.3
Kopczynski, C.4
-
56
-
-
31044441482
-
Latrunculin B effects on trabecular meshwork and corneal endothelial morphology in monkeys
-
Sabanay I, Tian B, Gabelt BT, Geiger B, Kaufman PL. Latrunculin B effects on trabecular meshwork and corneal endothelial morphology in monkeys. Exp. Eye Res. 82(2), 236-246 (2006).
-
(2006)
Exp. Eye Res.
, vol.82
, Issue.2
, pp. 236-246
-
-
Sabanay, I.1
Tian, B.2
Gabelt, B.T.3
Geiger, B.4
Kaufman, P.L.5
-
57
-
-
0033941239
-
H-7 effects on the structure and fluid conductance of monkey trabecular meshwork
-
Sabanay I, Gabelt BT, Tian B, Kaufman PL, Geiger B. H-7 effects on the structure and fluid conductance of monkey trabecular meshwork. Arch. Ophthalmol. 118(7), 955-962 (2000).
-
(2000)
Arch. Ophthalmol.
, vol.118
, Issue.7
, pp. 955-962
-
-
Sabanay, I.1
Gabelt, B.T.2
Tian, B.3
Kaufman, P.L.4
Geiger, B.5
-
58
-
-
0345550305
-
Functional and structural reversibility of H-7 effects on the conventional aqueous outflow pathway in monkeys
-
Sabanay I, Tian B, Gabelt BT, Geiger B, Kaufman PL. Functional and structural reversibility of H-7 effects on the conventional aqueous outflow pathway in monkeys. Exp. Eye Res. 78(1), 137-150 (2004).
-
(2004)
Exp. Eye Res.
, vol.78
, Issue.1
, pp. 137-150
-
-
Sabanay, I.1
Tian, B.2
Gabelt, B.T.3
Geiger, B.4
Kaufman, P.L.5
-
59
-
-
39149130336
-
The mechanism of increasing outflow facility by Rho-kinase inhibition with Y-27632 in bovine eyes
-
Lu Z, Overby DR, Scott PA, Freddo TF, Gong H. The mechanism of increasing outflow facility by Rho-kinase inhibition with Y-27632 in bovine eyes. Exp. Eye Res. 86(2), 271-281 (2008).
-
(2008)
Exp. Eye Res.
, vol.86
, Issue.2
, pp. 271-281
-
-
Lu, Z.1
Overby, D.R.2
Scott, P.A.3
Freddo, T.F.4
Gong, H.5
-
60
-
-
80055060174
-
Similar hydrodynamic and morphological changes in the aqueous humor outflow pathway after washout and Y27632 treatment in monkey eyes
-
Lu Z, Zhang Y, Freddo TF, Gong H. Similar hydrodynamic and morphological changes in the aqueous humor outflow pathway after washout and Y27632 treatment in monkey eyes. Exp. Eye Res. 93(4), 397-404 (2011).
-
(2011)
Exp. Eye Res.
, vol.93
, Issue.4
, pp. 397-404
-
-
Lu, Z.1
Zhang, Y.2
Freddo, T.F.3
Gong, H.4
-
61
-
-
0026538458
-
Modulation of outflow resistance by the pores of the inner wall endothelium
-
Johnson M, Shapiro A, Ethier CR, Kamm RD. Modulation of outflow resistance by the pores of the inner wall endothelium. Invest. Ophthalmol. Vis. Sci. 33(5), 1670-1675 (1992).
-
(1992)
Invest. Ophthalmol. Vis. Sci.
, vol.33
, Issue.5
, pp. 1670-1675
-
-
Johnson, M.1
Shapiro, A.2
Ethier, C.R.3
Kamm, R.D.4
-
62
-
-
0032410870
-
Acute and chronic structural effects of pilocarpine on monkey outflow tissues
-
Lutjen-Drecoll E, Wiendl H, Kaufman PL. Acute and chronic structural effects of pilocarpine on monkey outflow tissues. Trans. Am. Ophthalmol. Soc. 96, 171-191 (1998).
-
(1998)
Trans. Am. Ophthalmol. Soc.
, vol.96
, pp. 171-191
-
-
Lutjen-Drecoll, E.1
Wiendl, H.2
Kaufman, P.L.3
-
63
-
-
64249132761
-
Extracellular matrix turnover and outflow resistance
-
Keller KE, Aga M, Bradley JM, Kelley MJ, Acott TS. Extracellular matrix turnover and outflow resistance. Exp. Eye Res. 88(4), 676-682 (2009).
-
(2009)
Exp. Eye Res.
, vol.88
, Issue.4
, pp. 676-682
-
-
Keller, K.E.1
Aga, M.2
Bradley, J.M.3
Kelley, M.J.4
Acott, T.S.5
-
64
-
-
0017830237
-
Cytochalasin B-induced structural changes in the anterior ocular segment of the cynomolgus monkey
-
Svedbergh B, Lütjen-Drecoll E, Ober M, Kaufman PL. Cytochalasin B-induced structural changes in the anterior ocular segment of the cynomolgus monkey. Invest. Ophthalmol. Vis. Sci. 17(8), 718-734 (1978).
-
(1978)
Invest. Ophthalmol. Vis. Sci.
, vol.17
, Issue.8
, pp. 718-734
-
-
Svedbergh, B.1
Lütjen-Drecoll, E.2
Ober, M.3
Kaufman, P.L.4
-
65
-
-
0016366561
-
Studies on the cornea IX physiologic and morphologic effects of cytochalasin B on endothelium of rabbit corneas perfused in vitro
-
Kaye GI, Fenoglio CM, Hoefle FB, Fischbarg J. Studies on the cornea. IX. Physiologic and morphologic effects of cytochalasin B on endothelium of rabbit corneas perfused in vitro. J. Cell Biol. 61(2), 537-543 (1974).
-
(1974)
J. Cell Biol.
, vol.61
, Issue.2
, pp. 537-543
-
-
Kaye, G.I.1
Fenoglio, C.M.2
Hoefle, F.B.3
Fischbarg, J.4
-
66
-
-
33745577219
-
Effect of H-7 and Lat-B on retinal physiology
-
Kiland JA, Miller CL, Kim CB et al. Effect of H-7 and Lat-B on retinal physiology. Curr. Eye Res. 31(5), 441-455 (2006).
-
(2006)
Curr. Eye Res.
, vol.31
, Issue.5
, pp. 441-455
-
-
Kiland, J.A.1
Miller, C.L.2
Kim, C.B.3
-
67
-
-
0034827118
-
Acute effects of H-7 on ciliary epithelium and corneal endothelium in monkey eyes
-
Tian B, Sabanay I, Peterson JA, Hubbard WC, Geiger B, Kaufman PL. Acute effects of H-7 on ciliary epithelium and corneal endothelium in monkey eyes. Curr. Eye Res. 22(2), 109-120 (2001).
-
(2001)
Curr. Eye Res.
, vol.22
, Issue.2
, pp. 109-120
-
-
Tian, B.1
Sabanay, I.2
Peterson, J.A.3
Hubbard, W.C.4
Geiger, B.5
Kaufman, P.L.6
-
68
-
-
68349114963
-
Enhancement on primate corneal endothelial cell survival in vitro by a ROCK inhibitor
-
Okumura N, Ueno M, Koizumi N et al. Enhancement on primate corneal endothelial cell survival in vitro by a ROCK inhibitor. Invest. Ophthalmol. Vis. Sci. 50(8), 3680-3687 (2009).
-
(2009)
Invest. Ophthalmol. Vis. Sci.
, vol.50
, Issue.8
, pp. 3680-3687
-
-
Okumura, N.1
Ueno, M.2
Koizumi, N.3
-
69
-
-
41749091574
-
Applications for ROCK kinase inhibition
-
Olson MF. Applications for ROCK kinase inhibition. Curr. Opin. Cell Biol. 20(2), 242-248 (2008).
-
(2008)
Curr. Opin. Cell Biol.
, vol.20
, Issue.2
, pp. 242-248
-
-
Olson, M.F.1
-
71
-
-
0029320498
-
The inhibition of sodium, potassium-stimulated ATPase and corneal swelling: The role played by polyols
-
Whikehart DR. The inhibition of sodium, potassium-stimulated ATPase and corneal swelling: the role played by polyols. J. Am. Optom. Assoc. 66(6), 331-333 (1995).
-
(1995)
J. Am. Optom. Assoc.
, vol.66
, Issue.6
, pp. 331-333
-
-
Whikehart, D.R.1
-
72
-
-
77955876745
-
+-dependent ATPase activity and pump function in corneal endothelial cells
-
+-dependent ATPase activity and pump function in corneal endothelial cells. Invest. Ophthalmol. Vis. Sci. 51(8), 3935-3942 (2010).
-
(2010)
Invest. Ophthalmol. Vis. Sci.
, vol.51
, Issue.8
, pp. 3935-3942
-
-
Hatou, S.1
Yamada, M.2
Akune, Y.3
-
74
-
-
0036715441
-
Characterization and purification of truncated human Rho-kinase II expressed in Sf-21 cells
-
Turner MS, Fen-Fen-Lin, Trauger JW, Stephens J, LoGrasso P. Characterization and purification of truncated human Rho-kinase II expressed in Sf-21 cells. Arch. Biochem. Biophys. 405(1), 13-20 (2002).
-
(2002)
Arch. Biochem. Biophys.
, vol.405
, Issue.1
, pp. 13-20
-
-
Turner, M.S.1
Fen-Fen-Lin Trauger, J.W.2
Stephens, J.3
LoGrasso, P.4
-
75
-
-
0022491419
-
++dependent protein kinase
-
++dependent protein kinase. Biochem. Biophys. Res. Commun. 135(2), 397-402 (1986).
-
(1986)
Biochem. Biophys. Res. Commun.
, vol.135
, Issue.2
, pp. 397-402
-
-
Tamaoki, T.1
Nomoto, H.2
Takahashi, I.3
Kato, Y.4
Morimoto, M.5
Tomita, F.6
-
76
-
-
78349294542
-
Advancements in ocular drug delivery
-
Weiner AL, Gilger BC. Advancements in ocular drug delivery. Vet. Ophthalmol. 13(6), 395-406 (2010).
-
(2010)
Vet. Ophthalmol.
, vol.13
, Issue.6
, pp. 395-406
-
-
Weiner, A.L.1
Gilger, B.C.2
-
77
-
-
0029917195
-
Polyester nanocapsules as new topical ocular delivery systems for cyclosporin A
-
Calvo P, Sanchez A, Martinez J et al. Polyester nanocapsules as new topical ocular delivery systems for cyclosporin A. Pharm. Res. 13(2), 311-315 (1996).
-
(1996)
Pharm. Res.
, vol.13
, Issue.2
, pp. 311-315
-
-
Calvo, P.1
Sanchez, A.2
Martinez, J.3
-
78
-
-
0026533838
-
Pharmacologic trabeculocanalotomy facilitating aqueous outflow by assaulting the meshwork cytoskeleton, junctional complexes, and extracellular matrix
-
Kaufman PL. Pharmacologic trabeculocanalotomy. Facilitating aqueous outflow by assaulting the meshwork cytoskeleton, junctional complexes, and extracellular matrix. Arch. Ophthalmol. 110(1), 34-36 (1992).
-
(1992)
Arch. Ophthalmol.
, vol.110
, Issue.1
, pp. 34-36
-
-
Kaufman, P.L.1
-
79
-
-
33744803156
-
Mechanisms of AAV transduction in glaucoma-associated human trabecular meshwork cells
-
Borrás T, Xue W, Choi VW et al. Mechanisms of AAV transduction in glaucoma-associated human trabecular meshwork cells. J. Gene Med. 8(5), 589-602 (2006).
-
(2006)
J. Gene Med.
, vol.8
, Issue.5
, pp. 589-602
-
-
Borrás, T.1
Xue, W.2
Choi, V.W.3
-
80
-
-
37549064309
-
Durable, safe, multi-gene lentiviral vector expression in feline trabecular meshwork
-
Khare PD, Loewen N, Teo W et al. Durable, safe, multi-gene lentiviral vector expression in feline trabecular meshwork. Mol. Ther. 16(1), 97-106 (2008).
-
(2008)
Mol. Ther.
, vol.16
, Issue.1
, pp. 97-106
-
-
Khare, P.D.1
Loewen, N.2
Teo, W.3
-
81
-
-
62549088292
-
Prolonged transgene expression with lentiviral vectors in the aqueous humor outflow pathway of nonhuman primates
-
Barraza RA, Rasmussen CA, Loewen N et al. Prolonged transgene expression with lentiviral vectors in the aqueous humor outflow pathway of nonhuman primates. Hum. Gene Ther. 20(3), 191-200 (2009).
-
(2009)
Hum. Gene Ther.
, vol.20
, Issue.3
, pp. 191-200
-
-
Barraza, R.A.1
Rasmussen, C.A.2
Loewen, N.3
-
82
-
-
75749107904
-
Self-complementary AAV virus (scAAV) safe and long-term gene transferin the trabecular meshwork of living rats and monkeys
-
Buie LK, Rasmussen CA, Porterfield EC et al. Self-complementary AAV virus (scAAV) safe and long-term gene transferin the trabecular meshwork of living rats and monkeys. Invest. Ophthalmol. Vis. Sci. 51(1), 236-248 (2010).
-
(2010)
Invest. Ophthalmol. Vis. Sci.
, vol.51
, Issue.1
, pp. 236-248
-
-
Buie, L.K.1
Rasmussen, C.A.2
Porterfield, E.C.3
-
83
-
-
33646200546
-
Caldesmon transgene expression disrupts focal adhesions in HTM cells and increases outflow facility in organ-cultured human and monkey anterior segments
-
Gabelt BT, Hu Y, Vittitow JL et al. Caldesmon transgene expression disrupts focal adhesions in HTM cells and increases outflow facility in organ-cultured human and monkey anterior segments. Exp. Eye Res. 82(6), 935-944 (2006).
-
(2006)
Exp. Eye Res.
, vol.82
, Issue.6
, pp. 935-944
-
-
Gabelt, B.T.1
Hu, Y.2
Vittitow, J.L.3
-
84
-
-
33746750169
-
Caldesmon effects on the actin cytoskeleton and cell adhesion in cultured HTM cells
-
Grosheva I, Vittitow JL, Goichberg P et al. Caldesmon effects on the actin cytoskeleton and cell adhesion in cultured HTM cells. Exp. Eye Res. 82(6), 945-958 (2006).
-
(2006)
Exp. Eye Res.
, vol.82
, Issue.6
, pp. 945-958
-
-
Grosheva, I.1
Vittitow, J.L.2
Goichberg, P.3
-
85
-
-
29244491953
-
The effect of C3 transgene expression on actin and cellular adhesions in cultured human trabecular meshwork cells and on outflow facility in organ cultured monkey eyes
-
Liu X, Hu Y, Filla MS et al. The effect of C3 transgene expression on actin and cellular adhesions in cultured human trabecular meshwork cells and on outflow facility in organ cultured monkey eyes. Mol. Vis. 11, 1112-1121 (2005).
-
(2005)
Mol. Vis.
, vol.11
, pp. 1112-1121
-
-
Liu, X.1
Hu, Y.2
Filla, M.S.3
-
86
-
-
24144445945
-
Expression of dominant negative Rho-binding domain of Rho-kinase in organ cultured human eye anterior segments increases aqueous humor outflow
-
Rao PV, Deng P, Maddala R, Epstein DL, Li CY, Shimokawa H. Expression of dominant negative Rho-binding domain of Rho-kinase in organ cultured human eye anterior segments increases aqueous humor outflow. Mol. Vis. 11, 288-297 (2005).
-
(2005)
Mol. Vis.
, vol.11
, pp. 288-297
-
-
Rao, P.V.1
Deng, P.2
Maddala, R.3
Epstein, D.L.4
Li, C.Y.5
Shimokawa, H.6
-
87
-
-
84859196682
-
Production and flow of aqueous humor
-
11th Edition). Levin LA, Nilsson SFE, Ver Hoeve J, Wu SM (Eds). Elsevier Inc., Edinburgh, UK
-
Gabelt BT, Kaufman PL. Production and flow of aqueous humor. In: Adler's Physiology of the Eye (11th Edition). Levin LA, Nilsson SFE, Ver Hoeve J, Wu SM (Eds). Elsevier Inc., Edinburgh, UK, 274-307 (2011).
-
(2011)
Adler's Physiology of the Eye
, pp. 274-307
-
-
Gabelt, B.T.1
Kaufman, P.L.2
|