A major role for the Rho-associated coiled coil forming protein kinase in G-protein-mediated Ca2+ sensitization through inhibition of myosin phosphatase in rabbit trachea

British Journal of Pharmacology

Volumn 128, Issue 4, 1999, Pages 925-933

  Iizuka, Kunihiko ^a   Yoshii, Akihiro ^a   Samizo, Koichi ^a   Tsukagoshi, Hideo ^a   Ishizuka, Tamotsu ^a   Dobashi, Kunio ^a   Nakazawa, Tsugio ^a   Mori, Masatomo ^a  

^a GUNMA UNIVERSITY   (Japan)

Author keywords

Airway smooth muscle; Ca2+ sensitization; MLCK; PKC; ROCK; Y 27632

Indexed keywords

2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; 4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; ADENOSINE TRIPHOSPHATE; CALCIUM ION; CALCIUM SENSITIZER; CALYCULIN A; ENZYME INHIBITOR; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); MYOSIN LIGHT CHAIN KINASE; PHOSPHATASE; PHOSPHOTRANSFERASE; PROTEIN KINASE; PROTEIN KINASE C; RHO FACTOR; UNCLASSIFIED DRUG; WORTMANNIN;

ANIMAL TISSUE; ARTICLE; BREATHING MUSCLE; CONTROLLED STUDY; DOSE RESPONSE; ENZYME INHIBITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SMOOTH MUSCLE CONTRACTION; TRACHEA;

AMIDES; ANIMALS; CALCIUM; ENZYME INHIBITORS; GTP-BINDING PROTEINS; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); INDOLES; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALEIMIDES; MYOSIN-LIGHT-CHAIN PHOSPHATASE; PHORBOL 12,13-DIBUTYRATE; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN-SERINE-THREONINE KINASES; PYRIDINES; RABBITS; TRACHEA;

EID: 0032742546     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702864     Document Type: Article

References (44)

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