New mimetic peptides of the kinase-inhibitory region (KIR) of SOCS1 through focused peptide libraries

Biochemical Journal

Volumn 443, Issue 1, 2012, Pages 231-240

  Doti, Nunzianna ^a   Scognamiglio, Pasqualina L ^a   Madonna, Stefania ^b   Scarponi, Claudia ^b   Ruvo, Menotti ^a   Perretta, Giuseppe ^a   Albanesi, Cristina ^b   Marasco, Daniela ^a,c  

^a CNR   (Italy)

^b LABORATORIO DI PATOLOGIA VASCOLARE   (Italy)

^c UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Janus kinase signal transducer and activator of transcription pathway (JAK STAT pathway); Kinase inhibitory region (KIR); Mimetic peptide; Peptide library; Suppressor of cytokine signalling 1 (SOCS1)

Indexed keywords

GAMMA INTERFERON; INTERFERON REGULATORY FACTOR 1; JANUS KINASE 2; STAT1 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 1;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME STABILITY; HUMAN; HUMAN CELL; KERATINOCYTE; NORMAL HUMAN; PEPTIDE LIBRARY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; BINDING, COMPETITIVE; CATALYTIC DOMAIN; CELLS, CULTURED; CIRCULAR DICHROISM; DRUG EVALUATION, PRECLINICAL; DRUG STABILITY; HUMANS; INTERFERON REGULATORY FACTOR-1; JANUS KINASE 2; KERATINOCYTES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDE LIBRARY; PEPTIDES; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; STAT1 TRANSCRIPTION FACTOR; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS;

EID: 84858326728     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20111647     Document Type: Article

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