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Volumn 175, Issue 8, 2005, Pages 5077-5086

Treatment of mice with the suppressor of cytokine signaling-1 mimetic peptide, tyrosine kinase inhibitor peptide, prevents development of the acute form of experimental allergic encephalomyelitis and induces stable remission in the chronic relapsing/remitting form

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; GAMMA INTERFERON; INTERLEUKIN 2; INTERLEUKIN 5; INTERLEUKIN 6; MYELIN BASIC PROTEIN; MYELIN BASIC PROTEIN ANTIBODY; PROTEIN TYROSINE KINASE INHIBITOR; STAT1 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 1; SYNTHETIC PEPTIDE; TRANSCRIPTION FACTOR STAT1ALPHA; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR TAU; TYROSINE KINASE INHIBITOR PEPTIDE; UNCLASSIFIED DRUG;

EID: 26844548688     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.175.8.5077     Document Type: Article
Times cited : (64)

References (42)
  • 1
    • 1542673243 scopus 로고    scopus 로고
    • Non-receptor tyrosine kinases
    • Tsygankov, A. Y. 2003. Non-receptor tyrosine kinases. Front. Biosci. 8: S595-S635.
    • (2003) Front. Biosci. , vol.8
    • Tsygankov, A.Y.1
  • 2
    • 0035902180 scopus 로고    scopus 로고
    • Oncogenic kinase signalling
    • Blume-Jensen, P., and T. Hunter. 2001. Oncogenic kinase signalling. Nature 411: 355-365.
    • (2001) Nature , vol.411 , pp. 355-365
    • Blume-Jensen, P.1    Hunter, T.2
  • 3
    • 0037232108 scopus 로고    scopus 로고
    • Small molecule tyrosine kinase inhibitors: Clinical development of anticancer agents
    • Laird, A. D., and J. M. Cherrington. 2003. Small molecule tyrosine kinase inhibitors: clinical development of anticancer agents. Expert Opin. Investig. Drugs 12: 51-64.
    • (2003) Expert Opin. Investig. Drugs , vol.12 , pp. 51-64
    • Laird, A.D.1    Cherrington, J.M.2
  • 4
    • 0036635291 scopus 로고    scopus 로고
    • Glivec (STI571, imatinib), a rationally developed, targeted anticancer drug
    • Capdeville, R., E. Buchdunger, J. Zimmermann, and A. Matter. 2002. Glivec (STI571, imatinib), a rationally developed, targeted anticancer drug. Nat. Rev. Drug Discov. 1: 493-502.
    • (2002) Nat. Rev. Drug Discov. , vol.1 , pp. 493-502
    • Capdeville, R.1    Buchdunger, E.2    Zimmermann, J.3    Matter, A.4
  • 5
    • 0034658583 scopus 로고    scopus 로고
    • Jak-Stat signal transduction pathway through the eyes of cytokine class II receptor complexes
    • Kotenko, S. V., and S. Pestka. 2000. Jak-Stat signal transduction pathway through the eyes of cytokine class II receptor complexes. Oncogene 19: 2557-2567.
    • (2000) Oncogene , vol.19 , pp. 2557-2567
    • Kotenko, S.V.1    Pestka, S.2
  • 6
    • 1542493212 scopus 로고    scopus 로고
    • Negative regulation of cytokine signaling by CIS/SOCS family proteins and their roles in inflammatory diseases
    • Hanada, T., I. Kinjyo, K. Inagaki-Ohara, and A. Yoshimura. 2003. Negative regulation of cytokine signaling by CIS/SOCS family proteins and their roles in inflammatory diseases. Rev. Physiol. Biochem. Pharmacol. 149: 72-86.
    • (2003) Rev. Physiol. Biochem. Pharmacol. , vol.149 , pp. 72-86
    • Hanada, T.1    Kinjyo, I.2    Inagaki-Ohara, K.3    Yoshimura, A.4
  • 8
    • 0036986179 scopus 로고    scopus 로고
    • Suppressors of cytokine signalling: SOCS
    • Larsen, L., and C. Ropke. 2002. Suppressors of cytokine signalling: SOCS. APMIS 110: 833-844.
    • (2002) APMIS , vol.110 , pp. 833-844
    • Larsen, L.1    Ropke, C.2
  • 9
    • 3242661040 scopus 로고    scopus 로고
    • SOCS-1 suppresses TNF-α-induced apoptosis through the regulation of Jak activation
    • Kimura, A., T. Naka, S. Nagata, I. Kawase, and T. Kishimoto. 2004. SOCS-1 suppresses TNF-α-induced apoptosis through the regulation of Jak activation. Inter. Immunol. 16: 991-999.
    • (2004) Inter. Immunol. , vol.16 , pp. 991-999
    • Kimura, A.1    Naka, T.2    Nagata, S.3    Kawase, I.4    Kishimoto, T.5
  • 10
    • 0034624986 scopus 로고    scopus 로고
    • Signal transducers and activators of transcription (STAT)-induce STAT inhibitor-1 (SSI-1)/suppressor of cytokine signaling-1 (SOCS-1) suppresses tumor necrosis factor α-induced cell death in fibroblast
    • Morita, Y., T. Naka, Y. Kawazoe, M. Fujimoto, M. Narazaki, R. Nakagawa, H. Fukuyama, S. Nagata, and T. Kishimoto. 2000. Signal transducers and activators of transcription (STAT)-induce STAT inhibitor-1 (SSI-1)/suppressor of cytokine signaling-1 (SOCS-1) suppresses tumor necrosis factor α-induced cell death in fibroblast. Proc. Natl. Acad. Sci. USA 97: 5405-5410.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 5405-5410
    • Morita, Y.1    Naka, T.2    Kawazoe, Y.3    Fujimoto, M.4    Narazaki, M.5    Nakagawa, R.6    Fukuyama, H.7    Nagata, S.8    Kishimoto, T.9
  • 12
    • 16444371427 scopus 로고    scopus 로고
    • A SOCS-1 peptide mimetic inhibits both constitutive and IL-6 induced activation of STAT3 in prostate cancer cells
    • Flowers, L. O., P. Subramanaim, and H. Johnson. (2004). A SOCS-1 peptide mimetic inhibits both constitutive and IL-6 induced activation of STAT3 in prostate cancer cells. Oncogens 24: 2114-2120.
    • (2004) Oncogens , vol.24 , pp. 2114-2120
    • Flowers, L.O.1    Subramanaim, P.2    Johnson, H.3
  • 13
    • 0032526873 scopus 로고    scopus 로고
    • IFN-τ suppresses both the autoreactive humoral and cellular immune response and induces stable remission in mice with chronic experimental allergic encephalomyelitis
    • Mujtaba, M. G., W. Streit, and H. Johnson. 1998. IFN-τ suppresses both the autoreactive humoral and cellular immune response and induces stable remission in mice with chronic experimental allergic encephalomyelitis. Cell Immunol. 186: 94-102.
    • (1998) Cell Immunol. , vol.186 , pp. 94-102
    • Mujtaba, M.G.1    Streit, W.2    Johnson, H.3
  • 14
    • 0030965483 scopus 로고    scopus 로고
    • Oral feeding of interferon τ can prevent the acute and chronic relapsing forms of experimental allergic encephalomyelitis
    • Soos, J. M., M. G. Mujtaba, P. Subramaniam, W. Streit, and H. Johnson. 1997. Oral feeding of interferon τ can prevent the acute and chronic relapsing forms of experimental allergic encephalomyelitis. J. Neuroimmunol. 75: 43-50.
    • (1997) J. Neuroimmunol. , vol.75 , pp. 43-50
    • Soos, J.M.1    Mujtaba, M.G.2    Subramaniam, P.3    Streit, W.4    Johnson, H.5
  • 15
    • 4344708352 scopus 로고    scopus 로고
    • Cytokine-induced enhancement of autoimmune inflammation in the brain and spinal cord: Implications for multiple sclerosis
    • Sun, D., T. Newman, V. Perry, and R. Weller. 2004. Cytokine-induced enhancement of autoimmune inflammation in the brain and spinal cord: implications for multiple sclerosis. Neuropathol. Appl. Neurobiol. 30: 374-384.
    • (2004) Neuropathol. Appl. Neurobiol. , vol.30 , pp. 374-384
    • Sun, D.1    Newman, T.2    Perry, V.3    Weller, R.4
  • 16
    • 0031627202 scopus 로고    scopus 로고
    • Tumor necrosis factor-α induced pathology in the rat brain: Characterization of stereotaxic injection model
    • Glabinski, A., S. Krajewski, and J. Rafalowska. 1998. Tumor necrosis factor-α induced pathology in the rat brain: characterization of stereotaxic injection model. Folia Neuropathol. 36: 52-62.
    • (1998) Folia Neuropathol. , vol.36 , pp. 52-62
    • Glabinski, A.1    Krajewski, S.2    Rafalowska, J.3
  • 17
    • 0030272108 scopus 로고    scopus 로고
    • Global inhibition of IL-2 and IFN-γ secreting T cells precedes recovery from acute monophasic experimental autoimmune encephalomyelitis
    • Jensen, M. A., B. G. Arnason, A. Toscas, and A. Noronha. 1996. Global inhibition of IL-2 and IFN-γ secreting T cells precedes recovery from acute monophasic experimental autoimmune encephalomyelitis. J. Autoimmun. 9: 587-597.
    • (1996) J. Autoimmun. , vol.9 , pp. 587-597
    • Jensen, M.A.1    Arnason, B.G.2    Toscas, A.3    Noronha, A.4
  • 18
    • 0026707402 scopus 로고
    • Analysis of cytokine mRNA expression in the central nervous system of mice with experimental autoimmune encephalomyelitis reveals that IL-10 mRNA expression correlates with recovery
    • Kennedy, M. K., D. S. Torrance, K. S. Picha and K. M. Mohler. 1992. Analysis of cytokine mRNA expression in the central nervous system of mice with experimental autoimmune encephalomyelitis reveals that IL-10 mRNA expression correlates with recovery. J. Immunol. 149: 2496-2505.
    • (1992) J. Immunol. , vol.149 , pp. 2496-2505
    • Kennedy, M.K.1    Torrance, D.S.2    Picha, K.S.3    Mohler, K.M.4
  • 19
    • 0034607616 scopus 로고    scopus 로고
    • Interleukin-2 gene deletion produces a robust reduction in susceptibility to experimental autoimmune encephalomyelitis in C57BL/6 mice
    • Petitto, J. M., W. J. Streit, H. Z. uang, E. Butfiloski, and J. Schiffenbauer. 2000. Interleukin-2 gene deletion produces a robust reduction in susceptibility to experimental autoimmune encephalomyelitis in C57BL/6 mice. Neurosci. Lett. 285: 66-70.
    • (2000) Neurosci. Lett. , vol.285 , pp. 66-70
    • Petitto, J.M.1    Streit, W.J.2    Uang, H.Z.3    Butfiloski, E.4    Schiffenbauer, J.5
  • 20
    • 0345872052 scopus 로고    scopus 로고
    • Multiple sclerosis: Etiological mechanisms and future directions
    • Lutton, J. D., R. Winston, and T. C. Rodman. 2004. Multiple sclerosis: etiological mechanisms and future directions. Exp. Biol. Med. 229: 12-20.
    • (2004) Exp. Biol. Med. , vol.229 , pp. 12-20
    • Lutton, J.D.1    Winston, R.2    Rodman, T.C.3
  • 21
    • 0033998708 scopus 로고    scopus 로고
    • Cytokine secretion profile of myelin basic protein-specific T cells in multiple sclerosis
    • Rohowsky-Kochan, C., D. Molinaro, and S. D. Cook. 2000. Cytokine secretion profile of myelin basic protein-specific T cells in multiple sclerosis. Mult. Scler. 6: 69-77.
    • (2000) Mult. Scler. , vol.6 , pp. 69-77
    • Rohowsky-Kochan, C.1    Molinaro, D.2    Cook, S.D.3
  • 22
    • 0029076226 scopus 로고
    • The pregnancy recognition hormone, IFN-τ, blocks both development and superantigen reactivation of experimental allergic encephalomyelitis without associated toxicity
    • Soos, J. M., P. Subramaniam, A. Hobeika, J. Schiffenbauer, and H. Johnson. 1995. The pregnancy recognition hormone, IFN-τ, blocks both development and superantigen reactivation of experimental allergic encephalomyelitis without associated toxicity. J. Immunol. 155: 2747-2753.
    • (1995) J. Immunol. , vol.155 , pp. 2747-2753
    • Soos, J.M.1    Subramaniam, P.2    Hobeika, A.3    Schiffenbauer, J.4    Johnson, H.5
  • 24
    • 0026048131 scopus 로고
    • Antiproliferative activity of a pregnancy recognition hormone, ovine trophoblast protein-1
    • Pontzer, C. H., F. Bazer, and H. Johnson. 1991. Antiproliferative activity of a pregnancy recognition hormone, ovine trophoblast protein-1. Cancer Res. 51: 5304-5307.
    • (1991) Cancer Res. , vol.51 , pp. 5304-5307
    • Pontzer, C.H.1    Bazer, F.2    Johnson, H.3
  • 25
    • 26844455443 scopus 로고    scopus 로고
    • Epitopes on myelin proteins recognized by autoantibodies present in multiple sclerosis patients
    • Jaskiewicz, E. 2004. Epitopes on myelin proteins recognized by autoantibodies present in multiple sclerosis patients. Postepy. Hig. Med. Dosw. 58: 472-482.
    • (2004) Postepy. Hig. Med. Dosw. , vol.58 , pp. 472-482
    • Jaskiewicz, E.1
  • 26
    • 0028829252 scopus 로고
    • Suppression of experimental autoimmune myasthenia gravis and experimental allergic encephalomyelitis by oral administration of acetylcholine receptor and myelin basic protein: Double tolerance
    • Wang, Z., B. He, J. Qiao, and H. Link. 1995. Suppression of experimental autoimmune myasthenia gravis and experimental allergic encephalomyelitis by oral administration of acetylcholine receptor and myelin basic protein: double tolerance. J. Neuroimmunol. 63: 79-86.
    • (1995) J. Neuroimmunol. , vol.63 , pp. 79-86
    • Wang, Z.1    He, B.2    Qiao, J.3    Link, H.4
  • 27
    • 0025246367 scopus 로고
    • The T lymphocyte in experimental allergic encephalomyelitis
    • Zamvil, S., and L. Steinman. 1990. The T lymphocyte in experimental allergic encephalomyelitis. Annu. Rev. Immunol. 8: 579-621.
    • (1990) Annu. Rev. Immunol. , vol.8 , pp. 579-621
    • Zamvil, S.1    Steinman, L.2
  • 28
    • 0022974996 scopus 로고
    • T-cell epitope of the autoantigen myelin basic protein that induces encephalomyelitis
    • Zamvil, S., D. Mitchell, A. Moore, K. Kitamura, L. Steinman, and J. Rothbard. 1986. T-cell epitope of the autoantigen myelin basic protein that induces encephalomyelitis. Nature 324: 258-260.
    • (1986) Nature , vol.324 , pp. 258-260
    • Zamvil, S.1    Mitchell, D.2    Moore, A.3    Kitamura, K.4    Steinman, L.5    Rothbard, J.6
  • 29
    • 0024368359 scopus 로고
    • Encephalitogenic T cells in the B10. PL model of experimental allergic encephalomyelitis (EAE) are of the Th-1 lymphokine subtype
    • Ando, D., J. Clayton, D. Kono, J. Urban, and E. Sercarz. 1989. Encephalitogenic T cells in the B10. PL model of experimental allergic encephalomyelitis (EAE) are of the Th-1 lymphokine subtype. Cell. Immunol. 124: 132-143.
    • (1989) Cell. Immunol. , vol.124 , pp. 132-143
    • Ando, D.1    Clayton, J.2    Kono, D.3    Urban, J.4    Sercarz, E.5
  • 30
    • 0030894174 scopus 로고    scopus 로고
    • CD T suppressor cells mediate Interferon tau protection against experimental allergic encephalomyelitis
    • Mujtaba, M. G., J. Soos, and H. Johnson. 1997. CD T suppressor cells mediate Interferon tau protection against experimental allergic encephalomyelitis. J. Neuroimmunol. 75: 35-42.
    • (1997) J. Neuroimmunol. , vol.75 , pp. 35-42
    • Mujtaba, M.G.1    Soos, J.2    Johnson, H.3
  • 31
    • 0036721792 scopus 로고    scopus 로고
    • Oral type I IFN-τ promotes T-helper 2 bias and enhances suppression of encephalomyelitis by oral glatiramer acetate
    • Soos, J., O. Stuve, H. M. Johnson, H. L. Weiner, and S. S. Zamvil. 2002. Oral type I IFN-τ promotes T-helper 2 bias and enhances suppression of encephalomyelitis by oral glatiramer acetate. J. Immunol. 169: 2231-2235.
    • (2002) J. Immunol. , vol.169 , pp. 2231-2235
    • Soos, J.1    Stuve, O.2    Johnson, H.M.3    Weiner, H.L.4    Zamvil, S.S.5
  • 32
    • 0037565162 scopus 로고    scopus 로고
    • Investigation of a genetic variation of a variable number tandem repeat polymorphism of interleukin-6 gene in patients with multiple sclerosis
    • Schmidt, S., A. Papassotiropoulos, S. Sotgiu, H. Kolsch, G. Arru, M. Fois, C. Haase, S. Schmitz, N. Konig, M. Harzheim, et al. 2003. Investigation of a genetic variation of a variable number tandem repeat polymorphism of interleukin-6 gene in patients with multiple sclerosis. J. Neurol. 250: 607-611.
    • (2003) J. Neurol. , vol.250 , pp. 607-611
    • Schmidt, S.1    Papassotiropoulos, A.2    Sotgiu, S.3    Kolsch, H.4    Arru, G.5    Fois, M.6    Haase, C.7    Schmitz, S.8    Konig, N.9    Harzheim, M.10
  • 33
    • 0030659512 scopus 로고    scopus 로고
    • Defective TNF-α-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases
    • Kumar, A., M. Commane, T. Flickinger, C. Horvath, and G. Stark. 1997. Defective TNF-α-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases. Science 278: 1630-1632.
    • (1997) Science , vol.278 , pp. 1630-1632
    • Kumar, A.1    Commane, M.2    Flickinger, T.3    Horvath, C.4    Stark, G.5
  • 34
    • 4143095196 scopus 로고    scopus 로고
    • Activation of adenosine receptors inhibits tumor necrosis factor-a release by decreasing TNF-α mRNA stability and p38 activity
    • Fotheringham, J., M. Mayne, J. Grant, and J. Geiger. 2004. Activation of adenosine receptors inhibits tumor necrosis factor-a release by decreasing TNF-α mRNA stability and p38 activity. Eur. J. Pharmacol. 497: 87-85.
    • (2004) Eur. J. Pharmacol. , vol.497 , pp. 87-185
    • Fotheringham, J.1    Mayne, M.2    Grant, J.3    Geiger, J.4
  • 35
    • 0036142847 scopus 로고    scopus 로고
    • Regulation of signal transducer and activator of transcription and suppressor of cytokine-signaling gene expression in the brain of mice with astrocyte-targeted production of interleukin-12 or experimental autoimmune encephalomyelitis
    • Maier, J., C. Kincaid, A. Pagenstecher, and I. Campbell. 2002. Regulation of signal transducer and activator of transcription and suppressor of cytokine-signaling gene expression in the brain of mice with astrocyte-targeted production of interleukin-12 or experimental autoimmune encephalomyelitis. Am. J. Pathol. 160: 271-288.
    • (2002) Am. J. Pathol. , vol.160 , pp. 271-288
    • Maier, J.1    Kincaid, C.2    Pagenstecher, A.3    Campbell, I.4
  • 36
    • 11144233242 scopus 로고    scopus 로고
    • Suppressor of cytokine signaling (SOCS) proteins indirectly regulate toll-like receptor signaling in innate immune cells
    • Baetz, A., M. Frey, K. Heeg, and A. H. Dalpke. 2004. Suppressor of cytokine signaling (SOCS) proteins indirectly regulate toll-like receptor signaling in innate immune cells. J. Biol. Chem. 279: 54708-54715.
    • (2004) J. Biol. Chem. , vol.279 , pp. 54708-54715
    • Baetz, A.1    Frey, M.2    Heeg, K.3    Dalpke, A.H.4
  • 37
    • 12444347845 scopus 로고    scopus 로고
    • Role of tyrosine 441 of interferon-γ receptor subunit 1 in SOCS-1-mediated attenuation of STAT1 activation
    • Qing, Y., A. Costa-Pereira, D. Watling, and G. R. Stark. 2005. Role of tyrosine 441 of interferon-γ receptor subunit 1 in SOCS-1-mediated attenuation of STAT1 activation. J. Biol. Chem. 280: 1849-1853.
    • (2005) J. Biol. Chem. , vol.280 , pp. 1849-1853
    • Qing, Y.1    Costa-Pereira, A.2    Watling, D.3    Stark, G.R.4
  • 38
    • 0032803530 scopus 로고    scopus 로고
    • Cytokine-inducible SH2 protein-3 (CIS3/SOCS3) inhibits Janus tyrosine kinase by binding through the N-terminal kinase inhibitory region as well as SH2 domain
    • Sasaki, A., H. Yaukawa, A. Suzuki, S. Kaminzono, T. Syoda, I. Kinjyo, M. Sasaki, J. Johnston, and A. Yoshimura. 1999. Cytokine-inducible SH2 protein-3 (CIS3/SOCS3) inhibits Janus tyrosine kinase by binding through the N-terminal kinase inhibitory region as well as SH2 domain. Genes Cells 4: 339-351.
    • (1999) Genes Cells , vol.4 , pp. 339-351
    • Sasaki, A.1    Yaukawa, H.2    Suzuki, A.3    Kaminzono, S.4    Syoda, T.5    Kinjyo, I.6    Sasaki, M.7    Johnston, J.8    Yoshimura, A.9
  • 39
    • 0346121599 scopus 로고    scopus 로고
    • Suppressors of cytokine signaling and immunity
    • Kubo, M., T. Hanada, and A. Yoshimura. 2003. Suppressors of cytokine signaling and immunity. Nat. Immunol. 4: 1169-1176.
    • (2003) Nat. Immunol. , vol.4 , pp. 1169-1176
    • Kubo, M.1    Hanada, T.2    Yoshimura, A.3
  • 42
    • 0034726958 scopus 로고    scopus 로고
    • The JAK-inhibitor, JAB/SOCS-1 selectively inhibits cytokine-induced, but not v-Src induced JAK-STAT activation
    • Iwamoto, T., T. Senga, Y. Naito, S. Matsuda, Y. Miyake, A. Yoshimura, and M. Hamaguchi. 2000. The JAK-inhibitor, JAB/SOCS-1 selectively inhibits cytokine-induced, but not v-Src induced JAK-STAT activation. Oncogene 19: 4795-4801.
    • (2000) Oncogene , vol.19 , pp. 4795-4801
    • Iwamoto, T.1    Senga, T.2    Naito, Y.3    Matsuda, S.4    Miyake, Y.5    Yoshimura, A.6    Hamaguchi, M.7


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