메뉴 건너뛰기




Volumn 16, Issue 1, 2012, Pages 35-43

Regulation and dysregulation of epithelial Na + channels

Author keywords

Aldosterone; ENaC; Hypertension; Na + transport

Indexed keywords

ALDOSTERONE; CASPASE 2; EPITHELIAL SODIUM CHANNEL; ION CHANNEL; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PIOGLITAZONE; SERINE PROTEINASE; SERUM AND GLUCOCORTICOID REGULATED KINASE 1; SODIUM CHLORIDE COTRANSPORTER; TRANSFORMING GROWTH FACTOR BETA; UBIQUITIN PROTEIN LIGASE NEDD4;

EID: 84858291432     PISSN: 13421751     EISSN: 14377799     Source Type: Journal    
DOI: 10.1007/s10157-011-0496-z     Document Type: Review
Times cited : (44)

References (107)
  • 1
    • 0030945484 scopus 로고    scopus 로고
    • + channels: Function, structure, and regulation
    • + channels: function, structure, and regulation. Physiol Rev. 1997;77:359-96.
    • (1997) Physiol Rev , vol.77 , pp. 359-396
    • Garty, H.1    Palmer, L.G.2
  • 2
    • 0016792694 scopus 로고
    • Ion transport across excised bullfrog lung
    • Gatzy JT. Ion transport across excised bullfrog lung. Am J Physiol. 1975;228:1162-71.
    • (1975) Am J Physiol , vol.228 , pp. 1162-1171
    • Gatzy, J.T.1
  • 3
    • 0036307827 scopus 로고    scopus 로고
    • Epithelial sodium channel/degenerin family of ion channels: A variety of functions for a shared structure
    • Kellenberger S, Schild L. Epithelial sodium channel/degenerin family of ion channels: a variety of functions for a shared structure. Physiol Rev. 2002;82(3):735-67. (Pubitemid 34743337)
    • (2002) Physiological Reviews , vol.82 , Issue.3 , pp. 735-767
    • Kellenberger, S.1    Schild, L.2
  • 4
    • 0036197218 scopus 로고    scopus 로고
    • Epithelial sodium channel and the control of sodium balance: Interaction between genetic and environmental factors
    • DOI 10.1146/annurev.physiol.64.082101.143243
    • Rossier BC, Pradervand S, Schild L, Hummler E. Epithelial sodium channel and the control of sodium balance: interaction between genetic and environmental factors. Ann Rev Physiol. 2002;64:877-97. (Pubitemid 34259252)
    • (2002) Annual Review of Physiology , vol.64 , pp. 877-897
    • Rossier, B.C.1    Pradervand, S.2    Schild, L.3    Hummler, E.4
  • 6
    • 0034997951 scopus 로고    scopus 로고
    • Aldosterone induces rapid apical translocation of ENaC in early portion of renal collecting system: Possible role of SGK
    • Loffing J, Zecevic M, Feraille E, Asher C, Rossier BC, Firestone GL, et al. Aldosterone induces rapid apical translocation of ENaC in early portion of renal collecting system: possible role of SGK. Am J Physiol. 2001;280:F675-82.
    • (2001) Am J Physiol , vol.280
    • Loffing, J.1    Zecevic, M.2    Feraille, E.3    Asher, C.4    Rossier, B.C.5    Firestone, G.L.6
  • 7
    • 34147167759 scopus 로고    scopus 로고
    • Na channel expression and activity in the medullary collecting duct of rat kidney
    • DOI 10.1152/ajprenal.00399.2006
    • Frindt G, Ergonul Z, Palmer LG. Na channel expression and activity in the medullary collecting duct of rat kidney. Am J Physiol Renal Physiol. 2007;292:F1190-6. (Pubitemid 46572437)
    • (2007) American Journal of Physiology - Renal Physiology , vol.292 , Issue.4
    • Frindt, G.1    Ergonul, Z.2    Palmer, L.G.3
  • 12
    • 0001737526 scopus 로고    scopus 로고
    • Control of sodium transport by aldosterone
    • Seldin DW, Giebisch G, editors. Philadephia: Lippincott Williams and Wilkins
    • Verrey F, Hummler E, Schild L, Rossier B. Control of sodium transport by aldosterone. In: Seldin DW, Giebisch G, editors. The kidney: physiology and pathophysiology. Philadephia: Lippincott Williams and Wilkins; 2000. p. 1441-71.
    • (2000) The Kidney: Physiology and Pathophysiology , pp. 1441-1471
    • Verrey, F.1    Hummler, E.2    Schild, L.3    Rossier, B.4
  • 13
    • 0035006554 scopus 로고    scopus 로고
    • Activation of epithelial Na channels during short-term Na deprivation
    • Frindt G, Masilamani S, Knepper MA, Palmer LG. Activation of epithelial Na channels during short-term Na deprivation. Am J Physiol. 2001;280:F112-8.
    • (2001) Am J Physiol , vol.280
    • Frindt, G.1    Masilamani, S.2    Knepper, M.A.3    Palmer, L.G.4
  • 15
    • 0028053842 scopus 로고
    • Regulation of apical K and Na channels and Na/K pumps in rat cortical collecting tubule by dietary K
    • DOI 10.1085/jgp.104.4.693
    • Palmer LG, Antonian L, Frindt G. Regulation of apical K and Na channels and Na/K pumps in rat cortical collecting tubule by dietary K. J Gen Physiol. 1994;104:693-710. (Pubitemid 24328598)
    • (1994) Journal of General Physiology , vol.104 , Issue.4 , pp. 693-710
    • Palmer, L.G.1    Antonian, L.2    Frindt, G.3
  • 17
    • 0035936780 scopus 로고    scopus 로고
    • Molecular mechanisms of human hypertension
    • DOI 10.1016/S0092-8674(01)00241-0
    • Lifton RP, Gharavi AG, Geller DS. Molecular mechanisms of human hypertension. Cell. 2001;104:545-56. (Pubitemid 32201949)
    • (2001) Cell , vol.104 , Issue.4 , pp. 545-556
    • Lifton, R.P.1    Gharavi, A.G.2    Geller, D.S.3
  • 18
    • 0026580019 scopus 로고
    • A chimaeric 11 beta-hydroxylase/aldosterone synthase gene causes glucocorticoid-remediable aldosteronism and human hypertension
    • Lifton RP, Dluhy RG, Powers M, Rich GM, Cook S, Ulick S, et al. A chimaeric 11 beta-hydroxylase/aldosterone synthase gene causes glucocorticoid-remediable aldosteronism and human hypertension. Nature. 1992;355(6357):262-5.
    • (1992) Nature , vol.355 , Issue.6357 , pp. 262-265
    • Lifton, R.P.1    Dluhy, R.G.2    Powers, M.3    Rich, G.M.4    Cook, S.5    Ulick, S.6
  • 19
    • 0023743171 scopus 로고
    • Mineralocorticoid action: Target tissue specificity is enzyme, not receptor, mediated
    • Funder JW, Pearce PT, Smith R, Smith AI. Mineralocorticoid action: target tissue specificity is enzyme, not receptor, mediated. Science. 1988;242:583-5. (Pubitemid 18263202)
    • (1988) Science , vol.242 , Issue.4878 , pp. 583-585
    • Funder, J.W.1    Pearce, P.T.2    Smith, R.3    Smith, A.I.4
  • 20
    • 0031594450 scopus 로고    scopus 로고
    • Liddie syndrome: An autosomal dominant form of human hypertension
    • DOI 10.1046/j.1523-1755.1998.00728.x
    • Warnock DG. Liddle syndrome: an autosomal dominant form of human hypertension. Kidney Int. 1998;53:18-24. (Pubitemid 28066898)
    • (1998) Kidney International , vol.53 , Issue.1 , pp. 18-24
    • Warnock, D.G.1
  • 21
    • 33644876406 scopus 로고    scopus 로고
    • Central role for ENaC in development of hypertension
    • DOI 10.1681/ASN.2005050460
    • Pratt JH. Central role for ENaC in development of hypertension. J Am Soc Nephrol. 2005;16(11):3154-9. (Pubitemid 46179321)
    • (2005) Journal of the American Society of Nephrology , vol.16 , Issue.11 , pp. 3154-3159
    • Pratt, J.H.1
  • 22
    • 0001685674 scopus 로고
    • On the mechanism of action of aldosterone on sodium transport: The role of protein synthesis
    • Edelman IS, Bogoroch R, Porter GA. On the mechanism of action of aldosterone on sodium transport: the role of protein synthesis. Proc Natl Acad Sci USA. 1963;50:1169-77.
    • (1963) Proc Natl Acad Sci USA , vol.50 , pp. 1169-1177
    • Edelman, I.S.1    Bogoroch, R.2    Porter, G.A.3
  • 25
    • 0031778282 scopus 로고    scopus 로고
    • Regulation of rENaC mRNA by dietary NaCl and steroids: Organ, tissue, and steroid heterogeneity
    • Stokes JB, Sigmund RD. Regulation of rENaC mRNA by dietary NaCl and steroids: organ, tissue, and steroid heterogeneity. Am J Physiol. 1998;274(6 Pt 1):C1699-707. (Pubitemid 28304208)
    • (1998) American Journal of Physiology - Cell Physiology , vol.274 , Issue.6
    • Stokes, J.B.1    Sigmund, R.D.2
  • 28
    • 42949101343 scopus 로고    scopus 로고
    • Altered ENaC Expression Leads to Impaired Sodium Absorption in the Noninflamed Intestine in Crohn's Disease
    • DOI 10.1053/j.gastro.2008.02.030, PII S0016508508002813
    • Zeissig S, Bergann T, Fromm A, Bojarski C, Heller F, Guenther U, et al. Altered ENaC expression leads to impaired sodium absorption in the noninflamed intestine in Crohn's disease. Gastroenterology. 2008;134(5):1436-47. (Pubitemid 351615367)
    • (2008) Gastroenterology , vol.134 , Issue.5 , pp. 1436-1447
    • Zeissig, S.1    Bergann, T.2    Fromm, A.3    Bojarski, C.4    Heller, F.5    Guenther, U.6    Zeitz, M.7    Fromm, M.8    Schulzke, J.9
  • 30
    • 0033617192 scopus 로고    scopus 로고
    • Glucocorticoid induction of epithelial sodium channel expression in lung and renal epithelia occurs via trans-activation of a hormone response element in the 5′-flanking region of the human epithelial sodium channel alpha subunit gene
    • Sayegh R, Auerbach SD, Li X, Loftus RW, Husted RF, Stokes JB, et al. Glucocorticoid induction of epithelial sodium channel expression in lung and renal epithelia occurs via trans-activation of a hormone response element in the 5′-flanking region of the human epithelial sodium channel alpha subunit gene. J Biol Chem. 1999;274(18):12431-7.
    • (1999) J Biol Chem , vol.274 , Issue.18 , pp. 12431-12437
    • Sayegh, R.1    Auerbach, S.D.2    Li, X.3    Loftus, R.W.4    Husted, R.F.5    Stokes, J.B.6
  • 33
    • 42949113689 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 decreases epithelial sodium channel functionality in renal collecting duct cells via a Smad4-dependent pathway
    • Chang CT, Hung CC, Chen YC, Yen TH, Wu MS, Yang CW, et al. Transforming growth factor-beta1 decreases epithelial sodium channel functionality in renal collecting duct cells via a Smad4-dependent pathway. Nephrol Dial Transplant. 2008; 23(4):1126-34.
    • (2008) Nephrol Dial Transplant , vol.23 , Issue.4 , pp. 1126-1134
    • Chang, C.T.1    Hung, C.C.2    Chen, Y.C.3    Yen, T.H.4    Wu, M.S.5    Yang, C.W.6
  • 34
    • 0034761986 scopus 로고    scopus 로고
    • Pathogenesis of diabetic nephropathy: Focus on transforming growth factor-beta and connective tissue growth factor
    • DOI 10.1097/00041552-200111000-00001
    • Sakharova OV, Taal MW, Brenner BM. Pathogenesis of diabetic nephropathy: focus on transforming growth factor-beta and connective tissue growth factor. Curr Opin Nephrol Hypertens. 2001;10(6):727-38. (Pubitemid 33043665)
    • (2001) Current Opinion in Nephrology and Hypertension , vol.10 , Issue.6 , pp. 727-738
    • Sakharova, O.V.1    Taal, M.W.2    Brenner, B.M.3
  • 36
    • 65249106033 scopus 로고    scopus 로고
    • Thiazolidinedione-induced fluid retention is independent of collecting duct alphaENaC activity
    • Vallon V, Hummler E, Rieg T, Pochynyuk O, Bugaj V, Schroth J, et al. Thiazolidinedione-induced fluid retention is independent of collecting duct alphaENaC activity. J Am Soc Nephrol. 2009;20(4):721-9.
    • (2009) J Am Soc Nephrol , vol.20 , Issue.4 , pp. 721-729
    • Vallon, V.1    Hummler, E.2    Rieg, T.3    Pochynyuk, O.4    Bugaj, V.5    Schroth, J.6
  • 37
    • 0034992505 scopus 로고    scopus 로고
    • Immunocytochemical and immunoelectron microscopic localization of α, β and γ-ENaC in rat kidney
    • Hager H, Kwon TH, Vinnikova K, Masilamini S, Brooks H, Frokiaer J, et al. Immunocytochemical and immunoelectron microscopic localization of α, β and γ-ENaC in rat kidney. Am J Physiol. 2001;280:F1093-106.
    • (2001) Am J Physiol , vol.280
    • Hager, H.1    Kwon, T.H.2    Vinnikova, K.3    Masilamini, S.4    Brooks, H.5    Frokiaer, J.6
  • 38
    • 0033844619 scopus 로고    scopus 로고
    • Differential subcellular localization of ENaC subunits in mouse kidney in response to high- and low-Na diets
    • Loffing J, Pietri L, Aregger F, Bloch-Faure M, Ziegler U, Meneton P, et al. Differential subcellular localization of ENaC subunits in mouse kidney in response to high- and low-Na diets. Am J Physiol Renal Physiol. 2000;279(2):F252-8.
    • (2000) Am J Physiol Renal Physiol , vol.279 , Issue.2
    • Loffing, J.1    Pietri, L.2    Aregger, F.3    Bloch-Faure, M.4    Ziegler, U.5    Meneton, P.6
  • 39
    • 44349121823 scopus 로고    scopus 로고
    • Surface expression of epithelial Na channel protein in rat kidney
    • DOI 10.1085/jgp.200809989
    • Frindt G, Ergonul Z, Palmer LG. Surface expression of epithelial Na channel protein in rat kidney. J Gen Physiol. 2008; 131:617-27. (Pubitemid 351749201)
    • (2008) Journal of General Physiology , vol.131 , Issue.6 , pp. 617-627
    • Frindt, G.1    Ergonul, Z.2    Palmer, L.G.3
  • 40
    • 0036091599 scopus 로고    scopus 로고
    • Effects of aldosterone on biosynthesis, traffic, and functional expression of epithelial sodium channels in A6 cells
    • DOI 10.1085/jgp.20028559
    • Alvarez de la Rosa D, Li H, Canessa CM. Effects of aldosterone on biosynthesis, traffic, and functional expression of epithelial sodium channels in A6 cells. J Gen Physiol. 2002;119(5): 427-42. (Pubitemid 34522289)
    • (2002) Journal of General Physiology , vol.119 , Issue.5 , pp. 427-442
    • De La, R.D.A.1    Li, H.2    Canessa, C.M.3
  • 41
    • 20844435326 scopus 로고    scopus 로고
    • Role of Nedd4-2 and polyubiquitination in epithelial sodium channel degradation in untransfected renal A6 cells expressing endogenous ENaC subunits
    • DOI 10.1152/ajprenal.00179.2002
    • Malik B, Yue Q, Yue G, Chen XJ, Price SR, Mitch WE, et al. Role of Nedd4-2 and polyubiquitination in epithelial sodium channel degradation in untransfected renal A6 cells expressing endogenous ENaC subunits. Am J Physiol Renal Physiol. 2005;289(1):F107-16. (Pubitemid 40863578)
    • (2005) American Journal of Physiology - Renal Physiology , vol.289 , Issue.1
    • Malik, B.1    Yue, Q.2    Yue, G.3    Chen, X.J.4    Price, S.R.5    Mitch, W.E.6    Eaton, D.C.7
  • 42
    • 0034704119 scopus 로고    scopus 로고
    • Non-coordinate regulation of endogenous epithelial sodium channel (ENaC) subunit expression at the apical membrane of A6 cells in response to various transporting conditions
    • DOI 10.1074/jbc.M003822200
    • Weisz OA, Wang JM, Edinger RS, Johnson JP. Non-coordinate regulation of endogenous epithelial sodium channel (ENaC) subunit expression at the apical membrane of A6 cells in response to various transporting conditions. J Biol Chem. 2000;275(51):39886-93. (Pubitemid 32064608)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.51 , pp. 39886-39893
    • Weisz, O.A.1    Wang, J.-M.2    Edinger, R.S.3    Johnson, J.P.4
  • 43
    • 57349191615 scopus 로고    scopus 로고
    • Single-channel analysis of functional epithelial sodium channel (ENaC) stability at the apical membrane of A6 distal kidney cells
    • Yu L, Helms MN, Yue Q, Eaton DC. Single-channel analysis of functional epithelial sodium channel (ENaC) stability at the apical membrane of A6 distal kidney cells. Am J Physiol Renal Physiol. 2008;295(5):F1519-27.
    • (2008) Am J Physiol Renal Physiol , vol.295 , Issue.5
    • Yu, L.1    Helms, M.N.2    Yue, Q.3    Eaton, D.C.4
  • 45
    • 27844476338 scopus 로고    scopus 로고
    • + channel trafficking
    • + channel trafficking. Endocrinology. 2005;146(12):5079-85.
    • (2005) Endocrinology , vol.146 , Issue.12 , pp. 5079-5085
    • Snyder, P.M.1
  • 46
    • 33644875450 scopus 로고    scopus 로고
    • + transport in the distal nephron
    • + transport in the distal nephron. J Am Soc Nephrol. 2005;16:3167-74.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 3167-3174
    • Staub, O.1    Verrey, F.2
  • 51
    • 0037016772 scopus 로고    scopus 로고
    • + channel
    • DOI 10.1074/jbc.C100623200
    • Snyder PM, Olson DR, Thomas BC. Serum and glucocorticoid-regulated kinase modulates Nedd4-2-mediated inhibition of the epithelial Na+ channel. J Biol Chem. 2002;277(1):5-8. (Pubitemid 34952020)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.1 , pp. 5-8
    • Snyder, P.M.1    Olson, D.R.2    Thomas, B.C.3
  • 60
    • 38149123365 scopus 로고    scopus 로고
    • Aldosterone responsiveness of the epithelial sodium channel (ENaC) in colon is increased in a mouse model for Liddle's syndrome
    • Bertog M, Cuffe JE, Pradervand S, Hummler E, Hartner A, Porst M, et al. Aldosterone responsiveness of the epithelial sodium channel (ENaC) in colon is increased in a mouse model for Liddle's syndrome. J Physiol. 2008;586(2):459-75.
    • (2008) J Physiol , vol.586 , Issue.2 , pp. 459-475
    • Bertog, M.1    Cuffe, J.E.2    Pradervand, S.3    Hummler, E.4    Hartner, A.5    Porst, M.6
  • 61
    • 0032526243 scopus 로고    scopus 로고
    • Mutations causing Liddle syndrome reduce sodium-dependent downregulation of the epithelial sodium channel in the Xenopus oocyte expression system
    • Kellenberger S, Gautschi I, Rossier BC, Schild L. Mutations causing Liddle syndrome reduce sodium-dependent downregulation of the epithelial sodium channel in the Xenopus oocyte expression system. J Clin Invest. 1998;101:2741-50. (Pubitemid 28294583)
    • (1998) Journal of Clinical Investigation , vol.101 , Issue.12 , pp. 2741-2750
    • Kellenberger, S.1    Gautschi, I.2    Rossier, B.C.3    Schild, L.4
  • 62
    • 0030879756 scopus 로고    scopus 로고
    • An epithelial serine protease activates the amiloride-sensitive sodium channel
    • DOI 10.1038/39329
    • Vallet V, Chraibi A, Gaeggeler HP, Horisberger JD, Rossier BC. An epithelial serine protease activates the amiloride-sensitive sodium channel. Nature. 1997;389(6651):607-10. (Pubitemid 27446178)
    • (1997) Nature , vol.389 , Issue.6651 , pp. 607-610
    • Vallet, V.1    Chraibi, A.2    Gaeggeler, H.-P.3    Horisberger, J.-D.4    Rossier, B.C.5
  • 65
    • 0031930649 scopus 로고    scopus 로고
    • Protease modulation of the activity of the epithelial sodium channel expressed in Xenopus oocytes
    • DOI 10.1085/jgp.111.1.127
    • Chraibi A, Vallet V, Firsov D, Hess KS, Horisberger J-D. Protease modulation of the activity of the epithelial sodium channel expressed in Xenopus oocytes. J Gen Physiol. 1998;111:127-38. (Pubitemid 28063140)
    • (1998) Journal of General Physiology , vol.111 , Issue.1 , pp. 127-138
    • Chraibi, A.1    Vallet, V.2    Firsov, D.3    Hess, S.K.4    Horisberger, J.-D.5
  • 66
    • 33846995467 scopus 로고    scopus 로고
    • A novel neutrophil elastase inhibitor prevents elastase activation and surface cleavage of the epithelial sodium channel expressed in Xenopus laevis oocytes
    • DOI 10.1074/jbc.M605125200
    • Harris M, Firsov D, Vuagniaux G, Stutts MJ, Rossier BC. A novel neutrophil elastase inhibitor prevents elastase activation and surface cleavage of the epithelial sodium channel expressed in Xenopus laevis oocytes. J Biol Chem. 2007;282:58-64. (Pubitemid 47076633)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.1 , pp. 58-64
    • Harris, M.1    Firsov, D.2    Vuagniaux, G.3    Stutts, M.J.4    Rossier, B.C.5
  • 67
    • 53249109431 scopus 로고    scopus 로고
    • Cleavage in the {gamma}-subunit of the epithelial sodium channel (ENaC) plays an important role in the proteolytic activation of near-silent channels
    • Diakov A, Bera K, Mokrushina M, Krueger B, Korbmacher C. Cleavage in the {gamma}-subunit of the epithelial sodium channel (ENaC) plays an important role in the proteolytic activation of near-silent channels. J Physiol. 2008;586(Pt 19):4587-608.
    • (2008) J Physiol , vol.586 , Issue.PART 19 , pp. 4587-4608
    • Diakov, A.1    Bera, K.2    Mokrushina, M.3    Krueger, B.4    Korbmacher, C.5
  • 73
    • 33645465530 scopus 로고    scopus 로고
    • Activation of epithelial sodium channels by mouse channel activating proteases (mCAP) expressed in Xenopus oocytes requires catalytic activity of mCAP3 and mCAP2 but not mCAP1
    • Andreasen D, Vuagniaux G, Fowler-Jaeger N, Hummler E, Rossier BC. Activation of epithelial sodium channels by mouse channel activating proteases (mCAP) expressed in Xenopus oocytes requires catalytic activity of mCAP3 and mCAP2 but not mCAP1. J Am Soc Nephrol. 2006;17(4):968-76.
    • (2006) J Am Soc Nephrol , vol.17 , Issue.4 , pp. 968-976
    • Andreasen, D.1    Vuagniaux, G.2    Fowler-Jaeger, N.3    Hummler, E.4    Rossier, B.C.5
  • 76
    • 57049187776 scopus 로고    scopus 로고
    • Trypsin can activate the epithelial sodium channel (ENaC) in microdissected mouse distal nephron
    • Nesterov V, Dahlmann A, Bertog M, Korbmacher C. Trypsin can activate the epithelial sodium channel (ENaC) in microdissected mouse distal nephron. Am J Physiol Renal Physiol. 2008;295(4):F1052-62.
    • (2008) Am J Physiol Renal Physiol , vol.295 , Issue.4
    • Nesterov, V.1    Dahlmann, A.2    Bertog, M.3    Korbmacher, C.4
  • 77
    • 25444438993 scopus 로고    scopus 로고
    • Endogenous protease activation of ENaC: Effect of serine protease inhibition on ENaC single channel properties
    • DOI 10.1085/jgp.200509285
    • Adebamiro A, Cheng Y, Johnson JP, Bridges RJ. Endogenous protease activation of ENaC: effect of protease inhibition on ENaC single channel properties. J Gen Physiol. 2005;126: 339-52. (Pubitemid 41362653)
    • (2005) Journal of General Physiology , vol.126 , Issue.4 , pp. 339-352
    • Adebamiro, A.1    Cheng, Y.2    Johnson, J.P.3    Bridges, R.J.4
  • 79
    • 0036232705 scopus 로고    scopus 로고
    • Serine protease activity in M-1 cortical collecting duct cells
    • DOI 10.1161/01.HYP.0000013055.48885.8D
    • Liu L, Hering-Smith KS, Schiro FR, Hamm LL. Serine protease activity in m-1 cortical collecting duct cells. Hypertension. 2002;39(4):860-4. (Pubitemid 34437540)
    • (2002) Hypertension , vol.39 , Issue.4 , pp. 860-864
    • Liu, L.1    Hering-Smith, K.S.2    Schiro, F.R.3    Hamm, L.L.4
  • 81
    • 0016716991 scopus 로고
    • Studies on rat renal cortical cell kallikrein. I. Separation and measurement
    • Kaizu T, Margolius HS. Studies on rat renal cortical cell kallikrein. I. Separation and measurement. Biochim Biophys Acta. 1975;411(2):305-15.
    • (1975) Biochim Biophys Acta , vol.411 , Issue.2 , pp. 305-315
    • Kaizu, T.1    Margolius, H.S.2
  • 82
    • 0016363749 scopus 로고
    • Urinary kallikrein excretion in normal man. Relationships to sodium intake and sodium-retaining steroids
    • Margolius HS, Horwitz D, Geller RG, Alexander RW, Gill JR Jr, Pisano JJ, et al. Urinary kallikrein excretion in normal man. Relationships to sodium intake and sodium-retaining steroids. Circ Res. 1974;35(6):812-9.
    • (1974) Circ Res , vol.35 , Issue.6 , pp. 812-819
    • Margolius, H.S.1    Horwitz, D.2    Geller, R.G.3    Alexander, R.W.4    Gill Jr., J.R.5    Pisano, J.J.6
  • 84
    • 33644543413 scopus 로고    scopus 로고
    • Liddle's syndrome mutations increase Na+ transport through dual effects on epithelial Na+ channel surface expression and proteolytic cleavage
    • Knight KK, Olson DR, Zhou R, Snyder PM. Liddle's syndrome mutations increase Na+ transport through dual effects on epithelial Na+ channel surface expression and proteolytic cleavage. Proc Natl Acad Sci USA. 2006;103(8):2805-8.
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.8 , pp. 2805-2808
    • Knight, K.K.1    Olson, D.R.2    Zhou, R.3    Snyder, P.M.4
  • 85
    • 78951476724 scopus 로고    scopus 로고
    • + channel controls extracellular proteolytic channel activation via conformational change
    • + channel controls extracellular proteolytic channel activation via conformational change. J Biol Chem. 2011; 286(4):2416-24.
    • (2011) J Biol Chem , vol.286 , Issue.4 , pp. 2416-2424
    • Ruffieux-Daidie, D.1    Staub, O.2
  • 86
    • 55549140163 scopus 로고    scopus 로고
    • Intracellular sodium regulates proteolytic activation of the epithelial sodium channel
    • Knight KK, Wentzlaff DM, Snyder PM. Intracellular sodium regulates proteolytic activation of the epithelial sodium channel. J Biol Chem. 2008;283(41):27477-82.
    • (2008) J Biol Chem , vol.283 , Issue.41 , pp. 27477-27482
    • Knight, K.K.1    Wentzlaff, D.M.2    Snyder, P.M.3
  • 90
    • 0030033429 scopus 로고    scopus 로고
    • Gating of Na channels in the rat cortical collecting tubule: Effects of voltage and membrane stretch
    • DOI 10.1085/jgp.107.1.35
    • Palmer LG, Frindt G. Gating of Na channels in the rat cortical collecting tubule: Effects of voltage and membrane stretch. J Gen Physiol. 1996;107:35-45. (Pubitemid 26028779)
    • (1996) Journal of General Physiology , vol.107 , Issue.1 , pp. 35-45
    • Palmer, L.G.1    Frindt, G.2
  • 91
    • 33745761352 scopus 로고    scopus 로고
    • Open probability of the epithelial sodium channel is regulated by intracellular sodium
    • Anantharam A, Tian Y, Palmer LG. Open probability of the epithelial sodium channel is regulated by intracellular sodium. J Physiol. 2006;574(Pt 2):333-47.
    • (2006) J Physiol , vol.574 , Issue.PART 2 , pp. 333-347
    • Anantharam, A.1    Tian, Y.2    Palmer, L.G.3
  • 92
    • 0036023395 scopus 로고    scopus 로고
    • Na self inhibition of human epithelial Na channel: Temperature dependence and effect of extracellular proteases
    • DOI 10.1085/jgp.20028612
    • Chraibi A, Horisberger JD. Na self inhibition of human epithelial Na channel: temperature dependence and effect of extracellular proteases. J Gen Physiol. 2002;120(2):133-45. (Pubitemid 34857964)
    • (2002) Journal of General Physiology , vol.120 , Issue.2 , pp. 133-145
    • Chraibi, A.1    Horisberger, J.-D.2
  • 94
    • 0030989662 scopus 로고    scopus 로고
    • A molecular model for mechanosensation in Caenorhabditis elegans
    • Chalfie M. A molecular model for mechanosensation in Caenorhabditis elegans. Biol Bull. 1997;192(1):125. (Pubitemid 27126813)
    • (1997) Biological Bulletin , vol.192 , Issue.1 , pp. 125
    • Chalfie, M.1
  • 95
    • 0037134459 scopus 로고    scopus 로고
    • Interactions of beta and gammaENaC with Nedd4 can be facilitated by an ERK-mediated phosphorylation
    • DOI 10.1074/jbc.M111717200
    • Shi H, Asher C, Chigaev A, Yung Y, Reuveny E, Seger R, et al. Interactions of beta and gamma ENaC with Nedd4 can be facilitated by an ERK-mediated phosphorylation. J Biol Chem. 2002;277(16):13539-47. (Pubitemid 34967950)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.16 , pp. 13539-13547
    • Shi, H.1    Asher, C.2    Chigaev, A.3    Yung, Y.4    Reuveny, E.5    Seger, R.6    Garty, H.7
  • 96
    • 0037216230 scopus 로고    scopus 로고
    • Epidermal growth factor inhibits amiloride-sensitive sodium absorption in renal collecting duct cells
    • Shen JP, Cotton CU. Epidermal growth factor inhibits amiloride- sensitive sodium absorption in renal collecting duct cells. Am J Physiol Renal Physiol. 2003;284(1):F57-64. (Pubitemid 35471286)
    • (2003) American Journal of Physiology - Renal Physiology , vol.284 , Issue.1
    • Shen, J.-P.1    Cotton, C.U.2
  • 97
    • 28844506609 scopus 로고    scopus 로고
    • A novel role for glucocorticoid-induced leucine zipper protein in epithelial sodium channel-mediated sodium transport
    • DOI 10.1074/jbc.M508658200
    • Soundararajan R, Zhang TT, Wang J, Vandewalle A, Pearce D. A novel role for glucocorticoid-induced leucine zipper protein in epithelial sodium channel-mediated sodium transport. J Biol Chem. 2005;280(48):39970-81. (Pubitemid 41779132)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.48 , pp. 39970-39981
    • Soundararajan, R.1    Zhang, T.T.2    Wang, J.3    Vandewalle, A.4    Pearce, D.5
  • 99
    • 34548839405 scopus 로고    scopus 로고
    • Acute downregulation of ENaC by EGF involves the PY motif and putative ERK phosphorylation site
    • DOI 10.1085/jgp.200709775
    • Falin RA, Cotton CU. Acute downregulation of ENaC by EGF involves the PY motif and putative ERK phosphorylation site. J Gen Physiol. 2007;130(3):313-28. (Pubitemid 47443292)
    • (2007) Journal of General Physiology , vol.130 , Issue.3 , pp. 313-328
    • Falin, R.A.1    Cotton, C.U.2
  • 100
    • 33644675944 scopus 로고    scopus 로고
    • Progesterone down-regulates the open probability of the amiloride-sensitive epithelial sodium channel via a Nedd4-2-dependent mechanism
    • DOI 10.1074/jbc.M506308200
    • Michlig S, Harris M, Loffing J, Rossier BC, Firsov D. Progesterone down-regulates the open probability of the amiloridesensitive epithelial sodium channel via a Nedd4-2-dependent mechanism. J Biol Chem. 2005;280(46):38264-70. (Pubitemid 43853723)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.46 , pp. 38264-38270
    • Michlig, S.1    Harris, M.2    Loffing, J.3    Rossier, B.C.4    Firsov, D.5
  • 102
    • 0036023427 scopus 로고    scopus 로고
    • Synergistic activation of ENaC by three membrane-bound channel-activating serine proteases (mCAP1, mCAP2, and mCAP3) and serum- and glucocorticoid- regulated kinase (Sgk1) in Xenopus oocytes
    • DOI 10.1085/jgp.20028598
    • Vuagniaux G, Vallet V, Jaeger NF, Hummler E, Rossier BC. Synergistic activation of ENaC by three membrane-bound channel-activating serine proteases (mCAP1, mCAP2 and mCAP3) and serum- and glucocorticoid-regkulated kinase (Sgk1) in Xenopus oocytes. J Gen Physiol. 2002;120:191-201. (Pubitemid 34857968)
    • (2002) Journal of General Physiology , vol.120 , Issue.2 , pp. 191-201
    • Vuagniaux, G.1    Vallet, V.2    Jaeger, N.F.3    Hummler, E.4    Rossier, B.C.5
  • 105
    • 38349044024 scopus 로고    scopus 로고
    • Purinergic control of apical plasma membrane PI(4, 5)P2 levels sets ENaC activity in principal cells
    • Pochynyuk O, Bugaj V, Vandewalle A, Stockand JD. Purinergic control of apical plasma membrane PI(4, 5)P2 levels sets ENaC activity in principal cells. Am J Physiol Renal Physiol. 2008;294(1):F38-46.
    • (2008) Am J Physiol Renal Physiol , vol.294 , Issue.1
    • Pochynyuk, O.1    Bugaj, V.2    Vandewalle, A.3    Stockand, J.D.4
  • 107
    • 35948944949 scopus 로고    scopus 로고
    • + and water reabsorption
    • DOI 10.1096/fj.07-8807com
    • Rieg T, Bundey RA, Chen Y, Deschenes G, Junger W, Insel PA, et al. Mice lacking P2Y2 receptors have salt-resistant hypertension and facilitated renal Na+ and water reabsorption. FASEB J. 2007;21(13):3717-26. (Pubitemid 350075159)
    • (2007) FASEB Journal , vol.21 , Issue.13 , pp. 3717-3726
    • Rieg, T.1    Bundey, R.A.2    Chen, Y.3    Deschenes, G.4    Junger, W.5    Insel, P.A.6    Vallon, V.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.