A novel neutrophil elastase inhibitor prevents elastase activation and surface cleavage of the epithelial sodium channel expressed in Xenopus laevis oocytes

Journal of Biological Chemistry

Volumn 282, Issue 1, 2007, Pages 58-64

  Harris, Michael ^a   Firsov, Dmitri ^a   Vuagniaux, Grégoire ^b   Stutts, M Jackson ^c   Rossier, Bernard C ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b DEBIOPHARM SA   (Switzerland)

^c UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLEAVAGE PATTERN; EPITHELIAL SODIUM CHANNEL (ENAC); OOCYTES;

BIOLOGICAL ORGANS; ENZYME INHIBITION; PROTEOLYSIS; SODIUM;

CELLS;

LEUKOCYTE ELASTASE; LEUKOCYTE ELASTASE INHIBITOR; PROSTASIN; SODIUM CHANNEL; TRYPSIN; COMPLEMENTARY RNA; DEPELESTAT; ENZYME INHIBITOR; EPITHELIAL SODIUM CHANNEL; PEPTIDE; SERINE PROTEINASE; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ANIMAL CELL; ARTICLE; BIOTINYLATION; CELL MEMBRANE; CELL SURFACE; CONTROLLED STUDY; ENZYME ACTIVATION; FEMALE; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN DEGRADATION; XENOPUS LAEVIS; ANIMAL; CHEMISTRY; DRUG ANTAGONISM; METABOLISM; PHYSIOLOGY; PROTEIN ENGINEERING; SURFACE PROPERTY;

XENOPUS LAEVIS;

ANIMALS; CELL MEMBRANE; ENZYME ACTIVATION; ENZYME INHIBITORS; EPITHELIAL SODIUM CHANNEL; LEUKOCYTE ELASTASE; OOCYTES; PEPTIDES; PROTEIN ENGINEERING; RNA, COMPLEMENTARY; SERINE ENDOPEPTIDASES; SURFACE PROPERTIES; TRYPSIN; XENOPUS LAEVIS;

EID: 33846995467     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M605125200     Document Type: Article

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