Liddle's syndrome mutations increase Na+ transport through dual effects on epithelial Na+ channel surface expression and proteolytic cleavage

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 8, 2006, Pages 2805-2808

  Knight, Kristin K ^a   Olson, Diane R ^a   Zhou, Ruifeng ^a   Snyder, Peter M ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

Amiloride; Hypertension; Protease; Sodium

Indexed keywords

SODIUM CHANNEL; SODIUM ION; UBIQUITIN PROTEIN LIGASE E3; UBIQUITIN PROTEIN LIGASE NEDD4 2; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL SURFACE; CONTROLLED STUDY; GENE MUTATION; HUMAN; HUMAN CELL; LIDDLE SYNDROME; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; SODIUM TRANSPORT;

ANIMALS; BINDING SITES; CELL MEMBRANE; CELLS, CULTURED; EPITHELIAL CELLS; EPITHELIAL SODIUM CHANNEL; HUMANS; HYPERTENSION; MUTATION; RATS; SODIUM; SODIUM CHANNELS; SYNDROME; TRYPSIN; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES;

EID: 33644543413     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0511184103     Document Type: Article

References (25)

1. Schild, L. (2004) Rev. Physiol. Biochem. Pharmacol. 151, 93-107.
2. Snyder, P. M. (2005) Endocrinology 146, 5079-5085.
3. Lifton, R. P. (1996) Science 272, 676-680.
4. Snyder, P. M., Price, M. P., McDonald, F. J., Adams, C. M., Volk, K. A., Zeiher, B. G., Stokes, J. B. & Welsh, M. J. (1995) Cell 83, 969-978.
5. Firsov, D., Schild, L., Gautschi, I., Merillat, A. M., Schneeberger, E. & Rossier, B. C. (1996) Proc. Natl. Acad. Sci. USA 93, 15370-15375.
6. Staub, O., Dho, S., Henry, P., Correa, J., Ishikawa, T., McGlade, J. & Rotin, D. (1996) EMBO. J. 15, 2371-2380.
7. Kamynina, E., Debonneville, C., Bens, M., Vandewalle, A. & Staub, O. (2001) FASEB J. 15, 204-214.
8. Harvey, K. F., Dinudom, A., Cook, D. I. & Kumar, S. (2001) J. Biol. Chem. 276, 8597-8601.
9. Snyder, P. M., Steines, J. C. & Olson, D. R. (2004) J. Biol. Chem. 279, 5042-5046.
10. Schild, L., Canessa, C. M., Shimkets, R. A., Gautschi, I., Lifton, R. P. & Rossier, B. C. (1995) Proc. Natl. Acad. Sci. USA 92, 5699-5703.
11. Palmer, L. G. & Frindt, G. (1996) J. Gen. Physiol. 107, 35-45.
12. Fyfe, G. K. & Canessa, C. M. (1998) J. Gen. Physiol. 112, 423-432.
13. Hughey, R. P., Mueller, G. M., Bruns, J. B., Kinlough, C. L., Poland, P. A., Harkleroad, K. L., Carattino, M. D. & Kleyman, T. R. (2003) J. Biol. Chem. 278, 37073-37082.
14. Hughey, R. P., Bruns, J. B., Kinlough, C. L., Harkleroad, K. L., Tong, Q., Carattino, M. D., Johnson, J. P., Stockand, J. D. & Kleyman, T. R. (2004) J. Biol. Chem. 279, 18111-18114.
15. Vuagniaux, G., Vallet, V., Jaeger, N. F., Hummler, E. & Rossier, B. C. (2002) J. Gen. Physiol. 120, 191-201.
16. Chraibi, A., Vallet, V., Firsov, D., Hess, S. K. & Horisberger, J. D. (1998) J. Gen. Physiol. 111, 127-138.
17. Caldwell, R. A., Boucher, R. C. & Stutts, M. J. (2004) Am. J. Physiol. 286, C190-C194.
18. Hughey, R. P., Bruns, J. B., Kinlough, C. L. & Kleyman, T. R. (2004) J. Biol. Chem. 279, 48491-48494.
19. Snyder, P. M., Olson, D. R., Kabra, R., Zhou, R. & Steines, J. C. (2004) J. Biol. Chem. 279, 45753-45758.
20. Staub, O., Gautschi, I., Ishikawa, T., Breitschopf, K., Ciechanover, A., Schild, L. & Rotin, D. (1997) EMBO J. 16, 6325-6336.
21. Caldwell, R. A., Boucher, R. C. & Stutts, M. J. (2005) Am. J. Physiol. 288, L813-L819.
22. Adebamiro, A., Cheng, Y., Johnson, J. P. & Bridges, R. J. (2005) J. Gen. Physiol. 126, 339-352.
23. McDonald, F. J., Snyder, P. M., McCray, P. B., Jr., & Welsh, M. J. (1994) Am. J. Physiol. 266, L728-L734.
24. McDonald, F. J., Price, M. P., Snyder, P. M. & Welsh, M. J. (1995) Am. J. Physiol. 268, C1157-C1163.
25. Snyder, P. M., Olson, D. R. & Thomas, B. C. (2002) J. Biol. Chem. 277, 5-8.