Na channel expression and activity in the medullary collecting duct of rat kidney

American Journal of Physiology - Renal Physiology

Volumn 292, Issue 4, 2007, Pages

  Frindt, Gustavo ^a   Ergonul, Zuhal ^a   Palmer, Lawrence G ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Aldosterone; ENaC; Inner medulla; Outer medulla

Indexed keywords

AMILORIDE; SODIUM CHANNEL; SODIUM CHANNEL ALPHA; SODIUM CHANNEL BETA; SODIUM CHANNEL GAMMA; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; IMMUNOBLOTTING; KIDNEY COLLECTING TUBULE; KIDNEY CORTEX; KIDNEY MEDULLA; KIDNEY TUBULE ABSORPTION; MEMBRANE CURRENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEOMICS; RAT; WESTERN BLOTTING;

EID: 34147167759     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00399.2006     Document Type: Article

References (29)

1. Diezi J, Michoud P, Aceves J, Giebisch G. Micropuncture study of electrolyte transport across papillary collecting duct of the rat. Am J Physiol 224: 623-634, 1973.
2. Duc C, Farman N, Canessa C, Bonvalet JP, Rossier B. Cell-specific expression of epithelial sodium channel α, β and γ subunits in aldosterone-responsive epithelia from the rat: Localization by in situ hybridization and immunocytochemistry. J Cell Biol 127: 1907-1921, 1994.
3. Ergonul Z, Frindt G, Palmer LG. Regulation of maturation and processing of ENaC subunits in the rat kidney. Am J Physiol Renal Physiol 291: F683-F693, 2006.
4. Frindt G, Masilamani S, Knepper MA, Palmer LG. Activation of epithelial Na channels during short-term Na deprivation. Am J Physiol Renal Physiol 280: F112-F118, 2001.
5. Frindt G, Palmer LG. Na channels in the rat connecting tubule. Am J Physiol Renal Physiol 286: F669-F674, 2004.
6. + channels: function, structure, regulation. Physiol Rev 77: 359-396, 1997.
7. + secretion through apical low-conductance K channels in the CCD. Am J Physiol Renal Physiol 289: F117-F126, 2005.
8. Husted RF, Hayashi M, Stokes JB. Characteristics of papillary collecting duct cells in primary culture. Am J Physiol Renal Fluid Electrolyte Physiol 255: F1160-F1169, 1988.
9. Kellenberger S, Schild L. Epithelial sodium channel/degenerin family of ion channels: a variety of functions for a shared structure. Physiol Rev 82: 735-767, 2002.
10. Kim SW, Wang W, Kwon TH, Knepper MA, Frokiaer J, Nielsen S. Increased expression of ENaC subunits and increased apical targeting of AQP2 in the kidneys of spontaneously hypertensive rats. Am J Physiol Renal Physiol 289: F957-F968, 2005.
11. Kim SW, Wang W, Nielsen J, Praetorius J, Kwon TH, Knepper MA, Frokiaer J, Nielsen S. Increased expression and apical targeting of renal ENaC subunits in puromycin aminonucleoside-induced nephrotic syndrome in rats. Am J Physiol Renal Physiol 286: F922-F935, 2004.
12. Koeppen BM. Conductive properties of the rabbit outer medullary collecting duct: outer stripe. Am J Physiol Renal Fluid Electrolyte Physiol 250: F70-F76, 1986.
13. Koeppen BM. Conductive properties of the rabbit outer medullary collecting tubule: inner stripe. Am J Physiol Renal Fluid Electrolyte Physiol 248: F500-F506, 1985.
14. Masilamani S, Kim GH, Mitchell C, Wade JB, Knepper MA. Aldosterone-mediated regulation of ENaC alpha, beta, and gamma subunit proteins in rat kidney. J Clin Invest 104: R19-R23, 1999.
15. Masilamani S, Wang X, Kim GH, Brooks H, Nielsen J, Nielsen S, Nakamura K, Stokes JB, Knepper MA. Time course of renal Na-KATPase, NHE3, NKCC2, NCC, and ENaC abundance changes with dietary NaCl restriction. Am J Physiol Renal Physiol 283: F648-F657, 2002.
16. Pácha J, Frindt G, Antonian L, Silver R, Palmer LG. Regulation of Na channels of the rat cortical collecting tubule by aldosterone. J Gen Physiol 102: 25-42, 1993.
17. + channels from the apical membrane of the rat cortical collecting tubule. Proc Natl Acad Sci USA 83: 2767-2770, 1986.
18. Palmer LG, Frindt G. Gating of Na channels in the rat cortical collecting tubule: effects of voltage and membrane stretch. J Gen Physiol 107: 35-45, 1996.
19. Pfaller W. Structure function correlation on rat kidney. Adv Anat Embryol Cell Biol 70: 1-106, 1982.
20. Rocha AS, Kudo LH. Water, urea, sodium, chloride, and potassium transport in the in vitro isolated perfused papillary collecting duct. Kidney Int 22: 485-491, 1982.
21. Rubera I, Loffing J, Palmer LG, Frindt G, Fowler-Jaeger N, Sauter D, Carroll T, McMahon A, Hummler E, Rossier BC. Collecting duct specific gene inactivation of αENaC in the mouse kidney does not impair sodium and potassium balance. J Clin Invest 112: 554-565, 2003.
22. Sands JM, Nonoguchi H, Knepper MA. Hormone effects on NaCl permeability of rat inner medullary collecting duct. Am J Physiol Renal Fluid Electrolyte Physiol 255: F421-F428, 1988.
23. Sonnenberg H, Honrath U, Wilson DR. Effects of amiloride in the medullary collecting duct of rat kidney. Kidney Int 31: 1121-1125, 1987.
24. Stanton BA. Characterization of apical and basolateral membrane conductances of rat inner medullary collecting duct. Am J Physiol Renal Fluid Electrolyte Physiol 256: F862-F868, 1989.
25. Stokes JB. Ion transport by the cortical and outer medullary collecting tubule. Kidney Int 22: 473-484, 1982.
26. Stokes JB. Na and K transport across the cortical and outer medullary collecting tubule of the rabbit: evidence for diffusion across the outer medullary portion. Am J Physiol Renal Fluid Electrolyte Physiol 242: F514-F520, 1982.
27. 3 free solutions and of amiloride. Pflügers Arch 379: 49-52, 1979.
28. + channel in the apical membrane of the rat inner medullary collecting duct. J Clin Invest 96: 2748-2757, 1995.
29. Zeidel ML, Seifter JL, Lear S, Brenner BM, Silva P. Atrial peptides inhibit oxygen consumption in kidney medullary collecting duct cells. Am J Physiol Renal Fluid Electrolyte Physiol 251: F379-F383, 1986.