Transforming Growth Factor-β1 Decreases Expression of the Epithelial Sodium Channel αENaC and Alveolar Epithelial Vectorial Sodium and Fluid Transport via an ERK1/2-dependent Mechanism

Journal of Biological Chemistry

Volumn 278, Issue 45, 2003, Pages 43939-43950

  Frank, James ^a   Roux, Jérémie ^a   Kawakatsu, Hisaaki ^a   Su, George ^a   Dagenais, André ^c   Berthiaume, Yves ^c   Howard, Marybeth ^a   Canessa, Cecilia M ^b   Fang, Xiaohui ^a   Sheppard, Dean ^a   Matthay, Michael A ^a   Pittet, Jean François ^a,d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^d SAN FRANCISCO GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL ORGANS; CELLS; FLOW OF FLUIDS; MECHANICAL PERMEABILITY; MONOLAYERS; PROTEINS;

ACUTE LUNG INJURY (ALI);

BIOCHEMISTRY;

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; AMILORIDE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; DEXAMETHASONE; ENZYME INHIBITOR; GLUCOCORTICOID ANTAGONIST; INTERLEUKIN 1BETA; LUCIFERASE; MESSENGER RNA; MIFEPRISTONE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; OUABAIN; PROTEINASE INHIBITOR; RECOMBINANT TRANSFORMING GROWTH FACTOR BETA1; SODIUM 22; SODIUM CHANNEL; UNCLASSIFIED DRUG;

AIRWAY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APICAL MEMBRANE; ARTICLE; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPOTHESIS; IN VITRO STUDY; IN VIVO STUDY; LUNG ALVEOLUS CELL TYPE 2; LUNG ALVEOLUS EPITHELIUM; LUNG EDEMA; LUNG INJURY; MONOLAYER CULTURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; REPORTER GENE; SIGNAL TRANSDUCTION; SODIUM TRANSPORT; STATISTICAL SIGNIFICANCE; WATER TRANSPORT;

AMILORIDE; ANIMALS; BIOLOGICAL TRANSPORT; BODY FLUIDS; CELLS, CULTURED; DEXAMETHASONE; ENZYME ACTIVATION; EPITHELIAL CELLS; EPITHELIAL SODIUM CHANNEL; GENE EXPRESSION; GLUCOCORTICOIDS; HUMANS; LUCIFERASES; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; PROMOTER REGIONS (GENETICS); PULMONARY ALVEOLI; RATS; RATS, SPRAGUE-DAWLEY; RESPONSE ELEMENTS; RNA, MESSENGER; SODIUM; SODIUM CHANNELS; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1;

ANIMALIA; ESCHERICHIA COLI; STROPHANTHUS GRATUS;

EID: 0242666876     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M304882200     Document Type: Article

References (40)

1. Ware, L. B., and Matthay, M. A. (2000) N. Engl. J. Med. 342, 1334-1349
2. Ware, L. B., and Matthay, M. A. (2001) Am. J. Respir. Crit. Care Med. 163, 1376-1383
3. Matthay, M. A., and Wiener-Kronish, J. P. (1990) Am. Rev. Respir. Dis. 142, 1250-1257
4. Matthay, M. A., Folkesson, H. G., and Clerici, C. (2002) Physiol. Rev. 82, 569-600
5. Canessa, C. M., Merillat, A. M., and Rossier, B. C. (1994) Am. J. Physiol. 267, C1682-C1690
6. Hummler, E., Barker, P., Gatzy, J., Beermann, F., Verdumo, C., Schmidt, A., Boucher, R., and Rossier, B. C. (1996) Nat. Genet. 12, 325-328
7. McDonald, F. J., Yang, B., Hrstka, R. F., Drummond, H. A., Tarr, D. E., McCray, P. B., Jr., Stokes, J. B., Welsh, M. J., and Williamson, R. A. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 1727-1731
8. Barker, P. M., Nguyen, M. S., Gatzy, J. T., Grubb, B., Norman, H., Hummler, E., Rossier, B., Boucher, R. C., and Koller, B. (1998) J. Clin. Invest. 102, 1634-1640
9. Shull, M. M., Ormsby, I., Kier, A. B., Pawlowski, S., Diebold, R. J., Yin, M., Allen, R., Sidman, C., Proetzel, G., Calvin, D., Annunziata, N., and Doetschman, T. (1992) Nature 359, 693-699
10. Giri, S. N., Hyde, D. M., and Hollinger, M. A. (1993) Thorax 48, 959-966
11. Broekelmann, T. J., Limper, A. H., Colby, T. V., and McDonald, J. A. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 6642-6646
12. Kaminski, N., Allard, J. D., Pittet, J. F., Zuo, F., Griffiths, M. J., Morris, D., Huang, X., Sheppard, D., and Heller, R. A. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 1778-1783
13. Chesnutt, A. N., Matthay, M. A., Tibayan, F. A., and Clark, J. G. (1997) Am. J. Respir. Crit. Care Med. 156, 840-845
14. Clark, J. G., Milberg, J. A., Steinberg, K. P., and Hudson, L. D. (1995) Ann. Intern. Med. 122, 17-23
15. Hurst, V. I., Goldberg, P. L., Minnear, F. L., Heimark, R. L., and Vincent, P. A. (1999) Am. J. Physiol. 276, L582-L595
16. Chen, X. J., Jain, L., and Eaton, D. C. (2002) Am. J. Respir. Crit. Care Med. 165, 751 (abstr.)
17. McNicholas, C. M., and Canessa, C. M. (1997) J. Gen. Physiol. 109, 681-692
18. Pittet, J. F., Griffiths, M. J., Geiser, T., Kaminski, N., Dalton, S. L., Huang, X., Brown, L. A., Gotwals, P. J., Koteliansky, V. E., Matthay, M. A., and Sheppard, D. (2001) J. Clin. Invest. 107, 1537-1544
19. Fang, X., Ishigaki, M., Song, Y., Hirsch, J., and Matthay, M. (2003) Am. J. Respir. Crit. Care Med. 167, 564 (abstr.)
20. Ware, L., Wang, Y., Fang, X., Warnock, M., Sakuma, T., Hall, T., and Matthay, M. (2002) Lancet 360, 619-620
21. Hashimoto, S., Matsumoto, K., Gon, Y., Nakayama, T., Takeshita, I., and Horie, T. (1999) Am. J. Respir. Crit. Care Med. 159, 634-640
22. Furuichi, S., Hashimoto, S., Gon, Y., Matsumoto, K., and Horie, T. (2002) Respirology 7, 193-200
23. Suzuki, S., Zuege, D., and Berthiaume, Y. (1995) Am. J. Physiol. 268, L983-L990
24. Dagenais, A., Denis, C., Vives, M. F., Girouard, S., Masse, C., Nguyen, T., Yamagata, T., Grygorczyk, C., Kothary, R., and Berthiaume, Y. (2001) Am. J. Physiol. 281, L217-L230
25. Pittet, J. F., Lu, L. N., Morris, D. G., Modelska, K., Welch, W. J., Carey, H. V., Roux, J., and Matthay, M. A. (2001) J. Immunol. 166, 6301-6310
26. De La Rosa, D. A., Li, H., and Canessa, C. M. (2002) J. Gen. Physiol. 119, 427-442
27. Wang, A., Cohen, D. S., and Palmer, E. (1991) J. Biol. Chem. 266, 15598-15601
28. Mairbaurl, H., Mayer, K., Kim, K. J., Borok, Z., Bartsch, P., and Crandall, E. D. (2002) Am. J. Physiol. 282, L659-L665
29. Fang, X., Song, Y., Hirsch, J., Ishigaki, M., and Matthay, M. (2003) FASEB J. 17, 87 (abstr.)
30. Sartori, C., Fang, X., McGraw, D. W., Koch, P., Snider, M. E., Folkesson, H. G., and Matthay, M. A. (2002) J. Appl. Physiol. 93, 1875-1880
31. Frank, J. A., Gutierrez, J. A., Jones, K. D., Allen, L., Dobbs, L., and Matthay, M. A. (2002) Am. J. Respir. Crit. Care Med. 165, 242-249
32. Jain, L., Chen, X. J., Ramosevac, S., Brown, L. A., and Eaton, D. C. (2001) Am. J. Physiol. 280, L646-L658
33. Wang, H. C., Zentner, M. D., Deng, H. T., Kim, K. J., Wu, R., Yang, P. C., and Ann, D. K. (2000) J. Biol. Chem. 275, 8600-8609
34. Folkesson, H. G., Norlin, A., Wang, Y., Abedinpour, P., and Matthay, M. A. (2000) J. Appl. Physiol. 88, 416-424
35. Morris, R. G., and Schafer, J. A. (2002) J. Gen. Physiol. 120, 71-85
36. Yue, J., and Mulder, K. M. (2001) Pharmacol. Ther. 91, 1-34
37. Itani, O. A., Cornish, K. L., Liu, K. Z., and Thomas, C. P. (2003) Am. J. Physiol. 284, F778-F787
38. Pittet, J. F., Wiener-Kronish, J. P., McElroy, M. C., Folkessen, H. G., and Matthay, M. A. (1994) J. Clin. Invest. 94, 663-671
39. Planes, C., Blot-Chabaud, M., Matthay, M. A., Couette, S., Uchida, T., and Clerici, C. (2002) J. Biol. Chem. 277, 47318-47324
40. Fahy, R. J., Lichtenberger, F., McKeegan, C. B., Nuevo, G. J., Marsh, C. B., and Wewers, M. D. (2003) Am. J. Respir. Cell Mol. Biol. 28, 499-503