메뉴 건너뛰기




Volumn 122, Issue 4, 2012, Pages 165-176

DNA methylation as a biomarker for neuropsychiatric diseases

Author keywords

biomarker; DNA methylation; neuropsychiatric disorders

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; APOLIPOPROTEIN E; CYCLIN DEPENDENT KINASE INHIBITOR 2B; DNA; DNA METHYLTRANSFERASE 3B; DOPAMINE TRANSPORTER; FRAGILE X MENTAL RETARDATION PROTEIN; HOMOCYSTEINE; HOMOCYSTEINE INDUCED ENDOPLASMIC RETICULUM PROTEIN; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); OXYTOCIN RECEPTOR; PEPTIDYLPROLYL ISOMERASE; PEPTIDYLPROLYL ISOMERASE E LIKE; TELOMERASE REVERSE TRANSCRIPTASE; UNCLASSIFIED DRUG;

EID: 84858226590     PISSN: 00207454     EISSN: 15635279     Source Type: Journal    
DOI: 10.3109/00207454.2011.637654     Document Type: Article
Times cited : (29)

References (122)
  • 1
    • 0037372003 scopus 로고    scopus 로고
    • Epigenetic regulation of gene expression: How the genome integrates intrinsic and environmental signals
    • DOI 10.1038/ng1089
    • Jaenisch R, Bird A. Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat Genet. 2003;33(Suppl.):245-54. (Pubitemid 36278835)
    • (2003) Nature Genetics , vol.33 , Issue.SUPPL. , pp. 245-254
    • Jaenisch, R.1    Bird, A.2
  • 2
    • 70449725209 scopus 로고    scopus 로고
    • Epigeneticmechanisms in neurological diseases: Genes, syndromes, and therapies
    • Urdinguio RG, Sanchez-Mut JV, EstellerM. Epigeneticmechanisms in neurological diseases: genes, syndromes, and therapies. Lancet Neurol. 2009;8(11):1056-72.
    • (2009) Lancet Neurol. , vol.8 , Issue.11 , pp. 1056-1072
    • Urdinguio, R.G.1    Sanchez-Mut, J.V.2    Esteller, M.3
  • 4
    • 2642531973 scopus 로고    scopus 로고
    • Epigenetics in human disease and prospects for epigenetic therapy
    • DOI 10.1038/nature02625
    • Egger G, Liang G, Aparicio A, Jones PA. Epigenetics in human disease and prospects for epigenetic therapy. Nature. 2004;429(6990):457-63. (Pubitemid 38715140)
    • (2004) Nature , vol.429 , Issue.6990 , pp. 457-463
    • Egger, G.1    Liang, G.2    Aparicio, A.3    Jones, P.A.4
  • 5
    • 79956330964 scopus 로고    scopus 로고
    • CpG islands and the regulation of transcription
    • Deaton AM, Bird A. CpG islands and the regulation of transcription. Genes Dev. 2011;25(10):1010-22.
    • (2011) Genes Dev. , vol.25 , Issue.10 , pp. 1010-1022
    • Deaton, A.M.1    Bird, A.2
  • 6
    • 0035839126 scopus 로고    scopus 로고
    • Epigenetic reprogramming in mammalian development
    • DOI 10.1126/science.1063443
    • Reik W, Dean W, Walter J. Epigenetic reprogramming in mammalian development. Science. 2001;293(5532):1089-93. (Pubitemid 32758081)
    • (2001) Science , vol.293 , Issue.5532 , pp. 1089-1093
    • Reik, W.1    Dean, W.2    Walter, J.3
  • 7
    • 34250160167 scopus 로고    scopus 로고
    • Mechanisms regulating imprinted genes in clusters
    • DOI 10.1016/j.ceb.2007.04.013, PII S0955067407000658, Nucleus and Gene Expression
    • Edwards CA, Ferguson-Smith AC. Mechanisms regulating imprinted genes in clusters. Curr Opin Cell Biol. 2007;19(3):281-9. (Pubitemid 46899514)
    • (2007) Current Opinion in Cell Biology , vol.19 , Issue.3 , pp. 281-289
    • Edwards, C.A.1    Ferguson-Smith, A.C.2
  • 8
    • 78149478781 scopus 로고    scopus 로고
    • Aberrant epigenetic landscape in cancer: How cellular identity goes awry
    • Berdasco M, Esteller M. Aberrant epigenetic landscape in cancer: how cellular identity goes awry. Dev Cell. 2010;19(5):698-711.
    • (2010) Dev Cell. , vol.19 , Issue.5 , pp. 698-711
    • Berdasco, M.1    Esteller, M.2
  • 9
    • 40849139208 scopus 로고    scopus 로고
    • Epigenetics in cancer
    • Esteller M. Epigenetics in cancer. N Engl J Med. 2008; 358(11):1148-59.
    • (2008) N Engl J Med. , vol.358 , Issue.11 , pp. 1148-1159
    • Esteller, M.1
  • 10
    • 71849100252 scopus 로고    scopus 로고
    • Dissociated amyloid-beta antibody levels as a serum biomarker for the progression of Alzheimer's disease: A population-based study
    • Gustaw-Rothenberg KA, Siedlak SL, Bonda DJ, Lerner A, Tabaton M, Perry G, Smith MA. Dissociated amyloid-beta antibody levels as a serum biomarker for the progression of Alzheimer's disease: a population-based study. Exp Gerontol. 2010;45(1):47-52.
    • (2010) Exp Gerontol. , vol.45 , Issue.1 , pp. 47-52
    • Gustaw-Rothenberg, K.A.1    Siedlak, S.L.2    Bonda, D.J.3    Lerner, A.4    Tabaton, M.5    Perry, G.6    Smith, M.A.7
  • 14
    • 67149120534 scopus 로고    scopus 로고
    • Distinct regulation of cell cycle and survival in lymphocytes from patients with Alzheimer's disease and amyotrophic lateral sclerosis
    • Bartolome F,Munoz U, Esteras N, Esteban J, Bermejo-Pareja F, Martin-Requero A. Distinct regulation of cell cycle and survival in lymphocytes from patients with Alzheimer's disease and amyotrophic lateral sclerosis. Int J Clin Exp Pathol. 2009;2(4):390-8.
    • (2009) Int J Clin Exp Pathol. , vol.2 , Issue.4 , pp. 390-398
    • Bartolome Fmunoz, U.1    Esteras, N.2    Esteban, J.3    Bermejo-Pareja, F.4    Martin-Requero, A.5
  • 15
    • 72549104579 scopus 로고    scopus 로고
    • P53-mediated G(1)/S checkpoint dysfunction in lymphocytes from Alzheimer's disease patients
    • Zhou X, Jia J. P53-mediated G(1)/S checkpoint dysfunction in lymphocytes from Alzheimer's disease patients. Neurosci Lett. 2010;468(3):320-5.
    • (2010) Neurosci Lett. , vol.468 , Issue.3 , pp. 320-325
    • Zhou, X.1    Jia, J.2
  • 16
    • 39749173730 scopus 로고    scopus 로고
    • Telomere length in white blood cells, buccal cells and brain tissue and its variation with ageing and Alzheimer's disease
    • Thomas P, NJ OC, Fenech M. Telomere length in white blood cells, buccal cells and brain tissue and its variation with ageing and Alzheimer's disease. Mech Ageing Dev. 2008;129(4):183-90.
    • (2008) Mech Ageing Dev. , vol.129 , Issue.4 , pp. 183-190
    • Thomas, P.1    Oc, N.J.2    Fenech, M.3
  • 18
    • 77950833851 scopus 로고    scopus 로고
    • Altered cell viability and proliferation activity of peripheral lymphocytes in patients with Alzheimer's disease
    • Yoon SC, Kwon YA, Kim H, Kim S, Ahn Jo S, Kim DK. Altered cell viability and proliferation activity of peripheral lymphocytes in patients with Alzheimer's disease. Psychiatry Investig. 2010;7(1):68-71.
    • (2010) Psychiatry Investig. , vol.7 , Issue.1 , pp. 68-71
    • Yoon, S.C.1    Kwon, Y.A.2    Kim, H.3    Kim, S.4    Ahn Jo, S.5    Kim, D.K.6
  • 21
    • 33845332016 scopus 로고    scopus 로고
    • Respiratory-chain enzyme activities in isolated mitochondria of lymphocytes from patients with Parkinson's disease: Preliminary study
    • Shinde S, Pasupathy K. Respiratory-chain enzyme activities in isolated mitochondria of lymphocytes from patients with Parkinson's disease: preliminary study. Neurol India 2006;54(4):390-3. (Pubitemid 44870691)
    • (2006) Neurology India , vol.54 , Issue.4 , pp. 390-393
    • Shinde, S.1    Pasupathy, K.2
  • 23
    • 77549083834 scopus 로고    scopus 로고
    • Apoptosis of peripheral blood lymphocytes in Parkinson patients
    • Calopa M, Bas J, Callen A, Mestre M. Apoptosis of peripheral blood lymphocytes in Parkinson patients. Neurobiol Dis. 2010;38(1):1-7.
    • (2010) Neurobiol Dis. , vol.38 , Issue.1 , pp. 1-7
    • Calopa, M.1    Bas, J.2    Callen, A.3    Mestre, M.4
  • 24
    • 33645013396 scopus 로고    scopus 로고
    • Peripheral proteasome and caspase activity in Parkinson disease and Alzheimer disease
    • DOI 10.1212/01.wnl.0000198511.09968.b3, PII 0000611420060228000018
    • Blandini F, Sinforiani E, Pacchetti C, Samuele A, Bazzini E, Zangaglia R, Nappi G, Martignoni E. Peripheral proteasome and caspase activity in Parkinson disease and Alzheimer disease. Neurology. 2006;66(4):529-34. (Pubitemid 43739882)
    • (2006) Neurology , vol.66 , Issue.4 , pp. 529-534
    • Blandini, F.1    Sinforiani, E.2    Pacchetti, C.3    Samuele, A.4    Bazzini, E.5    Zangaglia, R.6    Nappi, G.7    Martignoni, E.8
  • 30
    • 68049111324 scopus 로고    scopus 로고
    • Lymphocyte proteomics of Parkinson's disease patients reveals cytoskeletal protein dysregulation and oxidative stress
    • Mila S, Albo AG, Corpillo D, Giraudo S, Zibetti M, Bucci EM, Lopiano L, Fasano M. Lymphocyte proteomics of Parkinson's disease patients reveals cytoskeletal protein dysregulation and oxidative stress. Biomark Med. 2009;3(2):117-28.
    • (2009) Biomark Med. , vol.3 , Issue.2 , pp. 117-128
    • Mila, S.1    Albo, A.G.2    Corpillo, D.3    Giraudo, S.4    Zibetti, M.5    Bucci, E.M.6    Lopiano, L.7    Fasano, M.8
  • 33
    • 0036267251 scopus 로고    scopus 로고
    • Reduced inositol content in lymphocyte-derived cell lines from bipolar patients
    • DOI 10.1034/j.1399-5618.2002.00108.x
    • Belmaker RH, Shapiro J, Vainer E, Nemanov L, Ebstein RP, Agam G. Reduced inositol content in lymphocyte-derived cell lines from bipolar patients. Bipolar Disord. 2002;4(1):67-9. (Pubitemid 34567278)
    • (2002) Bipolar Disorders , vol.4 , Issue.1 , pp. 67-69
    • Belmaker, R.H.1    Shapiro, J.2    Vainer, E.3    Nemanov, L.4    Ebstein, R.P.5    Agam, G.6
  • 34
    • 77955803943 scopus 로고    scopus 로고
    • Global methylation profiling of lymphoblastoid cell lines reveals epigenetic contributions to autism spectrum disorders and a novel autism candidate gene, RORA, whose protein product is reduced in autistic brain
    • Nguyen A, Rauch TA, Pfeifer GP, Hu VW. Global methylation profiling of lymphoblastoid cell lines reveals epigenetic contributions to autism spectrum disorders and a novel autism candidate gene, RORA, whose protein product is reduced in autistic brain. FASEB J. 2010;24(8):3036-51.
    • (2010) FASEB J. , vol.24 , Issue.8 , pp. 3036-3051
    • Nguyen, A.1    Rauch, T.A.2    Pfeifer, G.P.3    Hu, V.W.4
  • 37
    • 49949108971 scopus 로고    scopus 로고
    • Age-specific epigenetic drift in late-onset Alzheimer's disease
    • Wang SC, Oelze B, Schumacher A. Age-specific epigenetic drift in late-onset Alzheimer's disease. PLoS One. 2008;3(7):e2698.
    • (2008) PLoS One. , vol.3 , Issue.7
    • Wang, S.C.1    Oelze, B.2    Schumacher, A.3
  • 40
    • 27744443057 scopus 로고    scopus 로고
    • Methylated-CpG island recovery assay: A new technique for the rapid detection of methylated-CpG islands in cancer
    • DOI 10.1038/labinvest.3700311
    • Rauch T, Pfeifer GP. Methylated-CpG island recovery assay: a new technique for the rapid detection of methylated-CpG islands in cancer. Lab Invest. 2005;85(9):1172-80. (Pubitemid 43073989)
    • (2005) Laboratory Investigation , vol.85 , Issue.9 , pp. 1172-1180
    • Rauch, T.1    Pfeifer, G.P.2
  • 49
    • 39749152283 scopus 로고    scopus 로고
    • DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, neurogenesis and immune function
    • DOI 10.1093/hmg/ddm341
    • Jin B, Tao Q, Peng J, Soo HM, Wu W, Ying J, Fields CR, Delmas AL, Liu X, Qiu J, Robertson KD. DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, neurogenesis and immune function. Hum Mol Genet. 2008;17(5):690-709. (Pubitemid 351292258)
    • (2008) Human Molecular Genetics , vol.17 , Issue.5 , pp. 690-709
    • Jin, B.1    Tao, Q.2    Peng, J.3    Soo, H.M.4    Wu, W.5    Ying, J.6    Fields, C.R.7    Delmas, A.I.8    Liu, X.9    Qiu, J.10    Robertson, K.D.11
  • 58
    • 0033040396 scopus 로고    scopus 로고
    • A methylation PCR approach for detection of fragile X syndrome
    • DOI 10.1002/(SICI)1098-1004(1999)14:1<71::AID-HUMU9>3.0.CO;2-5
    • Panagopoulos I, Lassen C, Kristoffersson U, Aman P. A methylation PCR approach for detection of fragile X syndrome. Hum Mutat. 1999;14(1):71-9. (Pubitemid 29309946)
    • (1999) Human Mutation , vol.14 , Issue.1 , pp. 71-79
    • Panagopoulos, I.1    Lassen, C.2    Kristoffersson, U.3    Aman, P.4
  • 59
    • 34147221390 scopus 로고    scopus 로고
    • A homogeneous assay for analysis of FMR1 promoter methylation in patients with fragile X syndrome
    • DOI 10.1373/clinchem.2006.080762
    • Dahl C, Gronskov K, Larsen LA, Guldberg P, Brondum-Nielsen K. A homogeneous assay for analysis of FMR1 promoter methylation in patients with fragile X syndrome. Clin Chem. 2007;53(4):790-3. (Pubitemid 46580255)
    • (2007) Clinical Chemistry , vol.53 , Issue.4 , pp. 790-793
    • Dahl, C.1    Gronskov, K.2    Larsen, L.A.3    Guldberg, P.4    Brondum-Nielsen, K.5
  • 62
    • 79959234736 scopus 로고    scopus 로고
    • Highresolution methylation polymerase chain reaction for fragile X analysis: Evidence for novel FMR1 methylation patterns undetected in southern blot analyses
    • Chen L, Hadd AG, Sah S, Houghton JF, Filipovic-Sadic S, Zhang W, Hagerman PJ, Tassone F, Latham GJ. Highresolution methylation polymerase chain reaction for fragile X analysis: evidence for novel FMR1 methylation patterns undetected in southern blot analyses. Genet Med. 2011;13(6):528-38.
    • (2011) Genet Med. , vol.13 , Issue.6 , pp. 528-538
    • Chen, L.1    Hadd, A.G.2    Sah, S.3    Houghton, J.F.4    Filipovic-Sadic, S.5    Zhang, W.6    Hagerman, P.J.7    Tassone, F.8    Latham, G.J.9
  • 63
    • 79959243774 scopus 로고    scopus 로고
    • A new method for FMR1 gene methylation screening by multiplex methylation-specific real-time polymerase chain reaction
    • Elias MH, Ankathil R, Salmi AR, Sudhikaran W, Limprasert P, Zilfalil BA. A new method for FMR1 gene methylation screening by multiplex methylation-specific real-time polymerase chain reaction. Genet Test Mol Biomarkers. 2011;15(6):387-93.
    • (2011) Genet Test Mol Biomarkers. , vol.15 , Issue.6 , pp. 387-393
    • Elias, M.H.1    Ankathil, R.2    Salmi, A.R.3    Sudhikaran, W.4    Limprasert, P.5    Zilfalil, B.A.6
  • 65
    • 0026700732 scopus 로고
    • A DNA methylation imprint, determined by the sex of the parent, distinguishes the Angelman and Prader-Willi syndromes
    • Driscoll DJ, Waters MF, Williams CA, Zori RT, Glenn CC, Avidano KM, Nicholls RD. A DNA methylation imprint, determined by the sex of the parent, distinguishes the Angelman and Prader-Willi syndromes. Genomics. 1992;13(4):917-24.
    • (1992) Genomics. , vol.13 , Issue.4 , pp. 917-924
    • Driscoll, D.J.1    Waters, M.F.2    Williams, C.A.3    Zori, R.T.4    Glenn, C.C.5    Avidano, K.M.6    Nicholls, R.D.7
  • 66
    • 0026595355 scopus 로고
    • Molecular diagnosis of the Prader-Willi and Angelman syndromes by detection of parent-of-origin specific DNA methylation in 15q11-13
    • Dittrich B, Robinson WP, Knoblauch H, Buiting K, Schmidt K, Gillessen-KaesbachG,Horsthemke B.Molecular diagnosis of the Prader-Willi and Angelman syndromes by detection of parent-of-origin specific DNA methylation in 15q11-13. Hum Genet. 1992;90(3):313-5.
    • (1992) Hum Genet. , vol.90 , Issue.3 , pp. 313-315
    • Dittrich, B.1    Robinson, W.P.2    Knoblauch, H.3    Buiting, K.4    Schmidt, K.5    Gillessen-Kaesbach, G.6    Horsthemke, B.7
  • 68
    • 0029075773 scopus 로고
    • Diagnosing Prader-Willi syndrome
    • Young ID. Diagnosing Prader-Willi syndrome. Lancet. 1995;345(8965):1590.
    • (1995) Lancet. , vol.345 , Issue.8965 , pp. 1590
    • Young, I.D.1
  • 69
    • 0031737464 scopus 로고    scopus 로고
    • Evaluation of methylation analysis for diagnostic testing in 258 referrals suspected of Prader-Willi or Angelman syndromes
    • DOI 10.1007/s004390050866
    • Buchholz T, Jackson J, Robson L, Smith A. Evaluation of methylation analysis for diagnostic testing in 258 referrals suspected of Prader-Willi or Angelman syndromes. Hum Genet. 1998;103(5):535-9. (Pubitemid 28548474)
    • (1998) Human Genetics , vol.103 , Issue.5 , pp. 535-539
    • Buchholz, T.1    Jackson, J.2    Robson, L.3    Smith, A.4
  • 70
    • 77951964762 scopus 로고    scopus 로고
    • Practice guidelines for the molecular analysis of Prader-Willi and Angelman syndromes
    • Ramsden SC, Clayton-Smith J, Birch R, Buiting K. Practice guidelines for the molecular analysis of Prader-Willi and Angelman syndromes. BMC Med Genet. 2010;11:70.
    • (2010) BMC Med Genet. , vol.11 , pp. 70
    • Ramsden, S.C.1    Clayton-Smith, J.2    Birch, R.3    Buiting, K.4
  • 72
    • 0030047250 scopus 로고    scopus 로고
    • Alzheimer's disease in Finnish twins
    • DOI 10.1016/S0140-6736(96)91272-6
    • Raiha I, Kaprio J, Koskenvuo M, Klein C, Ludin HP. Alzheimer's disease in Finnish twins. Lancet. 1996;347(9001): 573-8. (Pubitemid 26070739)
    • (1996) Lancet , vol.347 , Issue.9001 , pp. 573-578
    • Raiha, I.1    Kaprio, J.2    Koskenvuo, M.3    Rajala, T.4    Sourander, L.5
  • 79
    • 2542541258 scopus 로고    scopus 로고
    • Parent-of-origin effect in multiple sclerosis: Observations in half-siblings
    • DOI 10.1016/S0140-6736(04)16304-6, PII S0140673604163046
    • Ebers GC, Sadovnick AD, Dyment DA, Yee IM, Willer CJ, Risch N. Parent-of-origin effect in multiple sclerosis: observations in half-siblings. Lancet. 2004;363(9423):1773-4. (Pubitemid 38698382)
    • (2004) Lancet , vol.363 , Issue.9423 , pp. 1773-1774
    • Ebers, G.C.1    Sadovnick, A.D.2    Dyment, D.A.3    Yee, I.M.L.4    Willer, C.J.5    Risch, N.6
  • 81
    • 77953469917 scopus 로고    scopus 로고
    • Epigenetics as a unifying principle in the aetiology of complex traits and diseases
    • Petronis A. Epigenetics as a unifying principle in the aetiology of complex traits and diseases. Nature. 2010;465(7299):721-7.
    • (2010) Nature. , vol.465 , Issue.7299 , pp. 721-727
    • Petronis, A.1
  • 83
    • 68949096744 scopus 로고    scopus 로고
    • Epigenetic differences in cortical neurons from a pair of monozygotic twins discordant for Alzheimer's disease
    • Mastroeni D, McKee A, Grover A, Rogers J, Coleman PD. Epigenetic differences in cortical neurons from a pair of monozygotic twins discordant for Alzheimer's disease. PLoS One. 2009;4(8):e6617.
    • (2009) PLoS One. , vol.4 , Issue.8
    • Mastroeni, D.1    McKee, A.2    Grover, A.3    Rogers, J.4    Coleman, P.D.5
  • 84
    • 0029440466 scopus 로고
    • Hypomethylation of the amyloid precursor protein gene in the brain of an Alzheimer's disease patient
    • West RL, Lee JM, Maroun LE. Hypomethylation of the amyloid precursor protein gene in the brain of an Alzheimer's disease patient. J Mol Neurosci. 1995;6(2):141-6.
    • (1995) J Mol Neurosci. , vol.6 , Issue.2 , pp. 141-146
    • West, R.L.1    Lee, J.M.2    Maroun, L.E.3
  • 85
    • 0033052929 scopus 로고    scopus 로고
    • Reduction with age in methylcytosine in the promoter region -224~-101 of the amyloid precursor protein gene in autopsy human cortex
    • DOI 10.1016/S0169-328X(99)00163-1, PII S0169328X99001631
    • Tohgi H, Utsugisawa K, Nagane Y, Yoshimura M, Genda Y, Ukitsu M. Reduction with age in methylcytosine in the promoter region-224 approximately-101 of the amyloid precursor protein gene in autopsy human cortex. Brain Res Mol Brain Res. 1999;70(2):288-92. (Pubitemid 29317643)
    • (1999) Molecular Brain Research , vol.70 , Issue.2 , pp. 288-292
    • Tohgi, H.1    Utsugisawa, K.2    Nagane, Y.3    Yoshimura, M.4    Genda, Y.5    Ukitsu, M.6
  • 86
    • 0032716797 scopus 로고    scopus 로고
    • The methylation status of cytosines in a τ gene promoter region alters with age to downregulate transcriptional activity in human cerebral cortex
    • DOI 10.1016/S0304-3940(99)00731-4, PII S0304394099007314
    • Tohgi H, Utsugisawa K, Nagane Y, Yoshimura M, Ukitsu M, Genda Y. The methylation status of cytosines in a tau gene promoter region alters with age to downregulate transcriptional activity in human cerebral cortex. Neurosci Lett. 1999;275(2):89-92. (Pubitemid 29502543)
    • (1999) Neuroscience Letters , vol.275 , Issue.2 , pp. 89-92
    • Tohgi, H.1    Utsugisawa, K.2    Nagane, Y.3    Yoshimura, M.4    Ukitsu, M.5    Genda, Y.6
  • 88
    • 77951842993 scopus 로고    scopus 로고
    • Methylation regulates alpha-synuclein expression and is decreased in Parkinson's disease patients' brains
    • Jowaed A, Schmitt I, Kaut O, Wullner U. Methylation regulates alpha-synuclein expression and is decreased in Parkinson's disease patients' brains. J Neurosci. 2010;30(18):6355-9.
    • (2010) J Neurosci. , vol.30 , Issue.18 , pp. 6355-6359
    • Jowaed, A.1    Schmitt, I.2    Kaut, O.3    Wullner, U.4
  • 89
    • 78649652766 scopus 로고    scopus 로고
    • CpG demethylation enhances alphasynuclein expression and affects the pathogenesis of Parkinson's disease
    • Matsumoto L, Takuma H, Tamaoka A, Kurisaki H, Date H, Tsuji S, Iwata A. CpG demethylation enhances alphasynuclein expression and affects the pathogenesis of Parkinson's disease. PLoS One. 2010;5(11):e15522.
    • (2010) PLoS One. , vol.5 , Issue.11
    • Matsumoto, L.1    Takuma, H.2    Tamaoka, A.3    Kurisaki, H.4    Date, H.5    Tsuji, S.6    Iwata, A.7
  • 90
    • 56449115830 scopus 로고    scopus 로고
    • Different methylation of the TNF-alpha promoter in cortex and substantia nigra: Implications for selective neuronal vulnerability
    • Pieper HC, Evert BO, Kaut O, Riederer PF,Waha A,Wullner U. Different methylation of the TNF-alpha promoter in cortex and substantia nigra: Implications for selective neuronal vulnerability. Neurobiol Dis. 2008;32(3):521-7.
    • (2008) Neurobiol Dis. , vol.32 , Issue.3 , pp. 521-527
    • Pieper, H.C.1    Evert, B.O.2    Kaut, O.3    Riederer, P.F.4    Waha, A.5    Wullner, U.6
  • 91
    • 34447334574 scopus 로고    scopus 로고
    • Peptidyl argininedeiminase 2 CpG island in multiple sclerosis white matter is hypomethylated
    • DOI 10.1002/jnr.21329
    • Mastronardi FG, Noor A, Wood DD, Paton T, Moscarello MA. Peptidyl argininedeiminase 2 CpG island in multiple sclerosis white matter is hypomethylated. J Neurosci Res. 2007;85(9):2006-16. (Pubitemid 47051489)
    • (2007) Journal of Neuroscience Research , vol.85 , Issue.9 , pp. 2006-2016
    • Mastronardi, F.G.1    Noor, A.2    Wood, D.D.3    Paton, T.4    Moscarello, M.A.5
  • 92
    • 57049160500 scopus 로고    scopus 로고
    • Evaluating epigenetic landmarks in the brain of multiple sclerosis patients: A contribution to the current debate on disease pathogenesis
    • Casaccia-Bonnefil P, Pandozy G, Mastronardi F. Evaluating epigenetic landmarks in the brain of multiple sclerosis patients: a contribution to the current debate on disease pathogenesis. Prog Neurobiol. 2008;86(4):368-78.
    • (2008) Prog Neurobiol. , vol.86 , Issue.4 , pp. 368-378
    • Casaccia-Bonnefil, P.1    Pandozy, G.2    Mastronardi, F.3
  • 95
    • 80054699616 scopus 로고    scopus 로고
    • Development of biomarkers for multiple sclerosis as a neurodegenerative disorder
    • Ziemann U, Wahl M, Hattingen E, Tumani H. Development of biomarkers for multiple sclerosis as a neurodegenerative disorder. Prog Neurobiol. 2011.
    • (2011) Prog Neurobiol.
    • Ziemann, U.1    Wahl, M.2    Hattingen, E.3    Tumani, H.4
  • 98
    • 77956479784 scopus 로고    scopus 로고
    • Contribution of genetic, epigenetic and transcriptomic differences to twin discordance in multiple sclerosis
    • Handunnetthi L, Handel AE, Ramagopalan SV. Contribution of genetic, epigenetic and transcriptomic differences to twin discordance in multiple sclerosis. Expert Rev Neurother. 2010;10(9):1379-81.
    • (2010) Expert Rev Neurother. , vol.10 , Issue.9 , pp. 1379-1381
    • Handunnetthi, L.1    Handel, A.E.2    Ramagopalan, S.V.3
  • 99
    • 0034060459 scopus 로고    scopus 로고
    • Twin studies of schizophrenia: From bow-and-arrow concordances to star wars Mx and functional genomics
    • DOI 10.1002/(SICI)1096-8628(200021)97:1<12::AID-AJMG3>3.0.CO;2-U
    • Cardno AG, Gottesman II. Twin studies of schizophrenia: from bow-and-arrow concordances to star wars Mx and functional genomics. Am J Med Genet. 2000;97(1):12-7. (Pubitemid 30257322)
    • (2000) American Journal of Medical Genetics - Seminars in Medical Genetics , vol.97 , Issue.1 , pp. 12-17
    • Cardno, A.G.1    Gottesman, I.I.2
  • 101
    • 0032954516 scopus 로고    scopus 로고
    • A population-based twin study of lifetime major depression in men and women
    • DOI 10.1001/archpsyc.56.1.39
    • Kendler KS, Prescott CA. A population-based twin study of lifetime major depression in men and women. Arch Gen Psychiatry. 1999;56(1):39-44. (Pubitemid 29055048)
    • (1999) Archives of General Psychiatry , vol.56 , Issue.1 , pp. 39-44
    • Kendler, K.S.1    Prescott, C.A.2
  • 103
    • 40849116456 scopus 로고    scopus 로고
    • Aberrant DNA methylation associated with bipolar disorder identified from discordant monozygotic twins
    • DOI 10.1038/sj.mp.4002001, PII 4002001
    • Kuratomi G, Iwamoto K, Bundo M, Kusumi I, Kato N, Iwata N, Ozaki N, Kato T. Aberrant DNA methylation associated with bipolar disorder identified from discordant monozygotic twins. Mol Psychiatry. 2008;13(4):429-41. (Pubitemid 351399814)
    • (2008) Molecular Psychiatry , vol.13 , Issue.4 , pp. 429-441
    • Kuratomi, G.1    Iwamoto, K.2    Bundo, M.3    Kusumi, I.4    Kato, N.5    Iwata, N.6    Ozaki, N.7    Kato, T.8
  • 104
    • 46949090009 scopus 로고    scopus 로고
    • Rapid publication: The relationship of 5HTT (SLC6A4) methylation and genotype on mRNA expression and liability to major depression and alcohol dependence in subjects from the Iowa adoption studies
    • DOI 10.1002/ajmg.b.30657
    • Philibert RA, Sandhu H, Hollenbeck N, Gunter T, AdamsW, Madan A. The relationship of 5HTT (SLC6A4) methylation and genotype on mRNA expression and liability to major depression and alcohol dependence in subjects from the Iowa Adoption Studies. Am J Med Genet B Neuropsychiatr Genet. 2008;147B(5):543-9. (Pubitemid 351961655)
    • (2008) American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics , vol.147 , Issue.5 , pp. 543-549
    • Philibert, R.A.1    Sandhu, H.2    Hollenbeck, N.3    Gunter, T.4    Adams, W.5    Madan, A.6
  • 107
    • 79953124177 scopus 로고    scopus 로고
    • The effects of EBV transformation on gene expression levels andmethylation profiles
    • Caliskan M, Cusanovich DA, Ober C, Gilad Y. The effects of EBV transformation on gene expression levels andmethylation profiles. Hum Mol Genet. 2011;20(8):1643-52.
    • (2011) Hum Mol Genet. , vol.20 , Issue.8 , pp. 1643-1652
    • Caliskan, M.1    Cusanovich, D.A.2    Ober, C.3    Gilad, Y.4
  • 111
    • 0026639650 scopus 로고
    • Oxytocin receptor distribution reflects social organization in monogamous and polygamous voles
    • Insel TR, Shapiro LE. Oxytocin receptor distribution reflects social organization in monogamous and polygamous voles. Proc Natl Acad Sci USA. 1992;89(13):5981-5.
    • (1992) Proc Natl Acad Sci USA. , vol.89 , Issue.13 , pp. 5981-5985
    • Insel, T.R.1    Shapiro, L.E.2
  • 112
    • 0036553050 scopus 로고    scopus 로고
    • The social deficits of the oxytocin knockout mouse
    • Winslow JT, Insel TR. The social deficits of the oxytocin knockout mouse. Neuropeptides. 2002;36(2-3):221-9.
    • (2002) Neuropeptides. , vol.36 , Issue.2-3 , pp. 221-229
    • Winslow, J.T.1    Insel, T.R.2
  • 114
    • 79960310830 scopus 로고    scopus 로고
    • Epigenetic and inflammatory marker profiles associated with depression in a community-based epidemiologic sample
    • UddinM, Koenen KC, Aiello AE,Wildman DE, de los Santos R, Galea S. Epigenetic and inflammatory marker profiles associated with depression in a community-based epidemiologic sample. Psychol Med. 2011;41(5):997-1007.
    • (2011) Psychol Med. , vol.41 , Issue.5 , pp. 997-1007
    • Uddin, M.1    Koenen, K.C.2    Aiello, A.E.3    Wildman, D.E.4    De Los Santos, R.5    Galea, S.6
  • 115
    • 0034033521 scopus 로고    scopus 로고
    • 12 status
    • DOI 10.1016/S0899-9007(99)00297-X, PII S089990079900297X
    • CravoML, Camilo ME.Hyperhomocysteinemia in chronic alcoholism: relations to folic acid and vitamins B(6) and B(12) status. Nutrition. 2000;16(4):296-302. (Pubitemid 30176058)
    • (2000) Nutrition , vol.16 , Issue.4 , pp. 296-302
    • Cravo, M.L.1    Camilo, M.E.2
  • 117
    • 58149353008 scopus 로고    scopus 로고
    • Promoter specific methylation of the dopamine transporter gene is altered in alcohol dependence and associated with craving
    • Hillemacher T, Frieling H, Hartl T, Wilhelm J, Kornhuber J, Bleich S. Promoter specific methylation of the dopamine transporter gene is altered in alcohol dependence and associated with craving. J Psychiatr Res. 2009;43(4):388-92.
    • (2009) J Psychiatr Res. , vol.43 , Issue.4 , pp. 388-392
    • Hillemacher, T.1    Frieling, H.2    Hartl, T.3    Wilhelm, J.4    Kornhuber, J.5    Bleich, S.6
  • 118
    • 33645368048 scopus 로고    scopus 로고
    • Epigenetic DNA hypermethylation of the HERP gene promoter induces down-regulation of its mRNA expression in patients with alcohol dependence
    • Bleich S, Lenz B, Ziegenbein M, Beutler S, Frieling H, Kornhuber J, Bonsch D. Epigenetic DNA hypermethylation of the HERP gene promoter induces down-regulation of its mRNA expression in patients with alcohol dependence. Alcohol Clin Exp Res. 2006;30(4):587-91.
    • (2006) Alcohol Clin Exp Res. , vol.30 , Issue.4 , pp. 587-591
    • Bleich, S.1    Lenz, B.2    Ziegenbein, M.3    Beutler, S.4    Frieling, H.5    Kornhuber, J.6    Bonsch, D.7
  • 119
    • 13844250333 scopus 로고    scopus 로고
    • DNA hypermethylation of the alpha synuclein promoter in patients with alcoholism
    • DOI 10.1097/00001756-200502080-00020
    • Bonsch D, Lenz B, Kornhuber J, Bleich S. DNA hypermethylation of the alpha synuclein promoter in patients with alcoholism. Neuroreport. 2005;16(2):167-70. (Pubitemid 40250393)
    • (2005) NeuroReport , vol.16 , Issue.2 , pp. 167-170
    • Bonsch, D.1    Lenz, B.2    Kornhuber, J.3    Bleich, S.4
  • 122
    • 77952519089 scopus 로고    scopus 로고
    • DNA methylation as a universal biomarker
    • Levenson VV. DNA methylation as a universal biomarker. Expert Rev Mol Diagn. 2010;10(4):481-8.
    • (2010) Expert Rev Mol Diagn. , vol.10 , Issue.4 , pp. 481-488
    • Levenson, V.V.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.