Rapid publication: MAOA methylation is associated with nicotine and alcohol dependence in women

American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics

Volumn 147, Issue 5, 2008, Pages 565-570

  Philibert, Robert A ^a,b,e   Gunter, Tracy D ^a   Beach, Steven R H ^c   Brody, Gene H ^c   Madan, Anup ^d  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c UNIVERSITY OF GEORGIA   (United States)

^d INSTITUTE FOR SYSTEMS BIOLOGY   (United States)

^e Psychiatry Research/MEB   (United States)

Author keywords

Alcohol dependence; Methylation; Monoamine oxidase A; Nicotine dependence; Variable nucleotide repeat

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; AMINE OXIDASE (FLAVIN CONTAINING); NICOTINE;

ADULT; ALCOHOLISM; ARTICLE; DNA METHYLATION; FEMALE; GENE LOCUS; GENOTYPE; HOMOZYGOSITY; HUMAN; LYMPHOBLAST; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROMOTER REGION; PSYCHOPATHY; SEX DIFFERENCE; SUBSTANCE ABUSE; SYMPTOM; TOBACCO DEPENDENCE; CASE CONTROL STUDY; CELL LINE; COMPARATIVE STUDY; ENZYMOLOGY; GENETICS; LYMPHOCYTE; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PILOT STUDY;

ADULT; ALCOHOLISM; ANTISOCIAL PERSONALITY DISORDER; BASE SEQUENCE; CASE-CONTROL STUDIES; CELL LINE, TRANSFORMED; DNA METHYLATION; FEMALE; HUMANS; LYMPHOCYTES; MALE; MOLECULAR SEQUENCE DATA; MONOAMINE OXIDASE; NICOTINE; PILOT PROJECTS; PROMOTER REGIONS (GENETICS); SEX FACTORS;

EID: 46949093048     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: 10.1002/ajmg.b.30778     Document Type: Article

References (41)

1. Agatsuma S, Lee M, Zhu H, et al. 2006. Monoamine oxidase A knockout mice exhibit impaired nicotine preference but normal responses to novel stimuli. Hum Mol Genet 15(18):2721-2731.
2. Association, AP. 1994. Diagnostic, statistical, manual of mental disorder. 4th edition. Washington, DC: American Psychiatric Association.
3. Berlin I, Anthenelli RM. 2001. Monoamine oxidases and tobacco smoking. Int J Neuropsychopharmacol 4(1):33-42.
4. Bradley SL, Dodelzon K, Sandhu HK, Philibert RA. 2005. Relationship of serotonin transporter gene polymorphisms and haplotypes to mRNA transcription. Am J Med Genet B Neuropsychiatr Genet 136(1):58-61.
5. Bucholz KK, Cadoret R, Cloninger CR, et al. 1994. A new, semi-structured psychiatric interview for use in genetic linkage studies: A report on the reliability of the SSAGA. J Stud Alcohol 55(2):149-158.
6. Caspi A, McClay J, Moffitt TE, et al. 2002. Role of genotype in the cycle of violence in maltreated children. Science 297(5582):851-854.
7. Caspi A, Sugden K, Moffitt TE, et al. 2003. Influence of life stress on depression: Moderation by a polymorphism in the 5-HTT gene. Science 301(5631):386-389.
8. Contini V, Marques FZ, Garcia CE, Hutz MH, Bau CH. 2006. MAOA-uVNTR polymorphism in a Brazilian sample: Further support for the association with impulsive behaviors and alcohol dependence. Am J Med Genet B Neuropsychiatr Genet 141(3):305-308.
9. David SP, Brown RA, Papandonatos GD, et al. 2007. Pharmacogenetic clinical trial of sustained-release bupropion for smoking cessation. Nicotine Tobacco Res 9(8):821-833.
10. Ehrich M, Nelson MR, Stanssens P, et al. 2005. Quantitative high-throughput analysis of DNA methylation patterns by base-specific cleavage and mass spectrometry. Proc Natl Acad Sci U S A 102(44): 15785-15790.
11. Ehrich M, Zoll S, Sur S, van den Boom D. 2007. A new method for accurate assessment of DNA quality after bisulfite treatment. Nucleic Acids Res 35(5):e29.
12. Fleiss JL. 1981. Statistical, methods for rates and proportions. 2nd edition. New York, NY: John Wiley & Sons Inc.
13. Frommer M, McDonald LE, Millar DS, et al. 1992. A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands. Proc Natl Acad Sci 89(5):1827-1831.
14. George TP, Weinberger AH. 2008. Monoamine oxidase inhibition for tobacco pharmacotherapy. Clin Pharmacol Ther 83(4):619-621.
15. Guillem K, Vouillac C, Azar MR, et al. 2006. Monoamine oxidase A rather than monoamine oxidase B inhibition increases nicotine reinforcement in rats. Eur J Neurosci 24(12):3532-3540.
16. Jaffee SR, Price TS. 2007. Gene-environment correlations: A review of the evidence and implications for prevention of mental illness. Mol Psychiatry 12(5):432-442.
17. Jin Y, Chen D, Hu Y, et al. 2006. Association between monoamine oxidase gene polymorphisms and smoking behaviour in Chinese males. Int J Neuropsychopharmacol 9(5):557-564.
18. Johnston CM, Lovell FL, Leongamornlert DA, et al. 2008. Large-scale population study of human cell lines indicates that dosage compensation is virtually complete. PLoS Genet 4(1):e9.
19. Kawaji H, Frith M, Katayama S, et al. 2006. Dynamic usage of transcription start sites within core promoters. Genome Biol 7(12):R118.
20. Kim-Cohen J, Caspi A, Taylor A, et al. 2006. MAOA, maltreatment, and gene-environment interaction predicting children's mental health: New evidence and a meta-analysis. Mol Psychiatry 11(10):903-913.
21. Klaus GGB. 1987. Lymphocytes. A practical approach. Oxford: IRL Press. 149-162.
22. Koller G, Bondy B, Preuss UW, Bottlender M, Soyka M. 2003. No association between a polymorphism in the promoter region of the MAOA gene with antisocial personality traits in alcoholics. Alcohol Alcohol 38(1):31-34.
23. Lahiri DK, Nurnberger JI Jr. 1991. A rapid non-enzymatic method for the preparation of HMW DNA from blood for RFLP studies. Nucleic Acids Res 19(19): 5444.
24. Lessov CN, Martin NG, Statham DJ, et al. 2004. Defining nicotine dependence for genetic research: Evidence from Australian twins. Psychol Med 34(05):865-879.
25. Levine M, Tjian R. 2003. Transcription regulation and animal diversity. Nature 424(6945):147-151.
26. Liang G, Lin JC, Wei V, et al. 2004. Distinct localization of histone H3 acetylation and H3-K4 methylation to the transcription start sites in the human genome. Proc Natl Acad Sci U S A 101(19):7357-7362.
27. Merril CR, Pratt ME. 1986. A silver stain for the rapid quantitative detection of proteins or nucleic acids on membranes or thin layer plates. Anal Biochem 156(1):96-110.
28. Miller DK, Wong EHF, Chesnut MD, Dwoskin LP. 2002. Reboxetine: Functional inhibition of monoamine transporters and nicotinic acetylcholine receptors. J Pharmacol Exp Ther 302(2):687-695.
29. Philibert RA, King BH, Winfield S, et al. 1998. Association of an X-chromosome dodecamer insertional variant allele with mental retardation. [erratum appears in Mol Psychiatry March 4, 1999;(2):197.]. Mol Psychiatry 3(4):303-309.
30. Philibert RA, Sandhu H, Hollenbeck N, et al. 2007a. The relationship of 5HTT methylation and genotype on mRNA expression and liability to major depression and alcohol dependence in subjects from the iowa adoption studies. Am J Med Genet B Neuropsychiatr Genet [epub ahead of publication].
31. Philibert R, Madan A, Andersen A, et al. 2007b. Serotonin transporter mRNA levels are associated with the methylation of an upstream CpG island. Am J Med Genet B Neuropsychiatr Genet 144(1):101-105.
32. Philibert RA, Ryu GY, Yoon JG, et al. 2007c. Transcriptional profiling of subjects from the Iowa adoption studies. Am J Med Genet B Neuropsychiatr Genet 144(5):683-690.
33. Philibert RA, Crowe R, Ryu GY, et al. 2007d. Transcriptional profiling of lymphoblast lines from subjects with panic disorder. Am J Med Genet B Neuropsychiatr Genet 144(5):674-682.
34. Sabol SZ, Hu S, Hamer D. 1998. A functional polymorphism in the monoamine oxidase A gene promoter. Hum Genet 103(3):273-279.
35. Saito T, Lachman HM, Diaz L, et al. 2002. Analysis of monoamine oxidase A (MAOA) promoter polymorphism in Finnish male alcoholics. Psychiatry Res 109(2):113-119.
36. Samochowiec J, Lesch KP, Rottmann M, et al. 1999. Association of a regulatory polymorphism in the promoter region of the monoamine oxidase A gene with antisocial alcoholism. Psychiatry Res 86(1):67-72.
37. Schmidt LG, Sander T, Kuhn S, et al. 2000. Different allele distribution of a regulatory MAOA gene promoter polymorphism in antisocial and anxious-depressive alcoholics. J Neural Transm 107(6):681-689.
38. Stranger BE, Nica AC, Forrest MS, et al. 2007. Population genomics of human gene expression. Nat Genet 39(10):1217-1224.
39. Villegier AS, Lotfipour S, McQuown SC, Belluzzi JD, Leslie FM. 2007. Tranylcypromine enhancement of nicotine self-administration. Neuropharmacology 52(6):1415-1425.
40. Wooters TE, Bardo MT. 2007. The monoamine oxidase inhibitor phenelzine enhances the discriminative stimulus effect of nicotine in rats. Behav Pharmacol 18(7):601-608.
41. Yates WR, Cadoret RJ, Troughton E, Stewart MA. 1996. An adoption study of DSM-IIIR alcohol and drug dependence severity. Drug Alcohol Dependence 41(1):9.