-
1
-
-
54149084585
-
Multiple sclerosis
-
Compston A., and Coles A. Multiple sclerosis. Lancet 372 9648 (2008) 1502-1517
-
(2008)
Lancet
, vol.372
, Issue.9648
, pp. 1502-1517
-
-
Compston, A.1
Coles, A.2
-
2
-
-
28544436950
-
Diagnostic criteria for multiple sclerosis: 2005 revisions to the "McDonald Criteria"
-
Polman C.H., Reingold S.C., Edan G., Filippi M., Hartung H.P., Kappos L., et al. Diagnostic criteria for multiple sclerosis: 2005 revisions to the "McDonald Criteria". Ann Neurol 58 6 (2005) 840-846
-
(2005)
Ann Neurol
, vol.58
, Issue.6
, pp. 840-846
-
-
Polman, C.H.1
Reingold, S.C.2
Edan, G.3
Filippi, M.4
Hartung, H.P.5
Kappos, L.6
-
3
-
-
3142556134
-
Development of biomarkers in multiple sclerosis
-
Bielekova B., and Martin R. Development of biomarkers in multiple sclerosis. Brain 127 Pt 7 (2004) 1463-1478
-
(2004)
Brain
, vol.127
, Issue.PART 7
, pp. 1463-1478
-
-
Bielekova, B.1
Martin, R.2
-
4
-
-
0038790058
-
Antimyelin antibodies as a predictor of clinically definite multiple sclerosis after a first demyelinating event
-
Berger T., Rubner P., Schautzer F., Egg R., Ulmer H., Mayringer I., et al. Antimyelin antibodies as a predictor of clinically definite multiple sclerosis after a first demyelinating event. N Engl J Med 349 2 (2003) 139-145
-
(2003)
N Engl J Med
, vol.349
, Issue.2
, pp. 139-145
-
-
Berger, T.1
Rubner, P.2
Schautzer, F.3
Egg, R.4
Ulmer, H.5
Mayringer, I.6
-
5
-
-
0028963171
-
Circulating, soluble adhesion proteins in cerebrospinal fluid and serum of patients with multiple sclerosis: correlation with clinical activity
-
Dore-Duffy P., Newman W., Balabanov R., Lisak R.P., Mainolfi E., Rothlein R., et al. Circulating, soluble adhesion proteins in cerebrospinal fluid and serum of patients with multiple sclerosis: correlation with clinical activity. Ann Neurol 37 1 (1995) 55-62
-
(1995)
Ann Neurol
, vol.37
, Issue.1
, pp. 55-62
-
-
Dore-Duffy, P.1
Newman, W.2
Balabanov, R.3
Lisak, R.P.4
Mainolfi, E.5
Rothlein, R.6
-
6
-
-
20844436120
-
Recommended standard of cerebrospinal fluid analysis in the diagnosis of multiple sclerosis: a consensus statement
-
Freedman M.S., Thompson E.J., Deisenhammer F., Giovannoni G., Grimsley G., Keir G., et al. Recommended standard of cerebrospinal fluid analysis in the diagnosis of multiple sclerosis: a consensus statement. Arch Neurol 62 6 (2005) 865-870
-
(2005)
Arch Neurol
, vol.62
, Issue.6
, pp. 865-870
-
-
Freedman, M.S.1
Thompson, E.J.2
Deisenhammer, F.3
Giovannoni, G.4
Grimsley, G.5
Keir, G.6
-
7
-
-
42149138598
-
Cerebrospinal fluid brain specific proteins in relation to nitric oxide metabolites during relapse of multiple sclerosis
-
Rejdak K., Petzold A., Stelmasiak Z., and Giovannoni G. Cerebrospinal fluid brain specific proteins in relation to nitric oxide metabolites during relapse of multiple sclerosis. Mult Scler 14 1 (2008) 59-66
-
(2008)
Mult Scler
, vol.14
, Issue.1
, pp. 59-66
-
-
Rejdak, K.1
Petzold, A.2
Stelmasiak, Z.3
Giovannoni, G.4
-
8
-
-
0031908175
-
Myelin basic protein in cerebrospinal fluid and other body fluids
-
Whitaker J.N. Myelin basic protein in cerebrospinal fluid and other body fluids. Mult Scler 4 1 (1998) 16-21
-
(1998)
Mult Scler
, vol.4
, Issue.1
, pp. 16-21
-
-
Whitaker, J.N.1
-
9
-
-
33748740746
-
Heterogeneity at the HLA-DRB1 locus and risk for multiple sclerosis
-
Barcellos L.F., Sawcer S., Ramsay P.P., Baranzini S.E., Thomson G., Briggs F., et al. Heterogeneity at the HLA-DRB1 locus and risk for multiple sclerosis. Hum Mol Genet 15 18 (2006) 2813-2824
-
(2006)
Hum Mol Genet
, vol.15
, Issue.18
, pp. 2813-2824
-
-
Barcellos, L.F.1
Sawcer, S.2
Ramsay, P.P.3
Baranzini, S.E.4
Thomson, G.5
Briggs, F.6
-
10
-
-
34548351247
-
Interleukin 7 receptor alpha chain (IL7R) shows allelic and functional association with multiple sclerosis
-
Gregory S.G., Schmidt S., Seth P., Oksenberg J.R., Hart J., Prokop A., et al. Interleukin 7 receptor alpha chain (IL7R) shows allelic and functional association with multiple sclerosis. Nat Genet 39 9 (2007) 1083-1091
-
(2007)
Nat Genet
, vol.39
, Issue.9
, pp. 1083-1091
-
-
Gregory, S.G.1
Schmidt, S.2
Seth, P.3
Oksenberg, J.R.4
Hart, J.5
Prokop, A.6
-
11
-
-
34548299105
-
Risk alleles for multiple sclerosis identified by a genomewide study
-
Hafler D.A., Compston A., Sawcer S., Lander E.S., Daly M.J., De Jager P.L., et al. Risk alleles for multiple sclerosis identified by a genomewide study. N Engl J Med 357 9 (2007) 851-862
-
(2007)
N Engl J Med
, vol.357
, Issue.9
, pp. 851-862
-
-
Hafler, D.A.1
Compston, A.2
Sawcer, S.3
Lander, E.S.4
Daly, M.J.5
De Jager, P.L.6
-
12
-
-
45549092100
-
The genetics of multiple sclerosis: SNPs to pathways to pathogenesis
-
Oksenberg J.R., Baranzini S.E., Sawcer S., and Hauser S.L. The genetics of multiple sclerosis: SNPs to pathways to pathogenesis. Nat Rev Genet 9 7 (2008) 516-526
-
(2008)
Nat Rev Genet
, vol.9
, Issue.7
, pp. 516-526
-
-
Oksenberg, J.R.1
Baranzini, S.E.2
Sawcer, S.3
Hauser, S.L.4
-
13
-
-
31344466008
-
DNA methylation and gene silencing in cancer
-
Baylin S.B. DNA methylation and gene silencing in cancer. Nat Clin Pract Oncol 2 Suppl 1 (2005) S4-S11
-
(2005)
Nat Clin Pract Oncol
, vol.2
, Issue.SUPPL. 1
-
-
Baylin, S.B.1
-
14
-
-
48849091231
-
Novel epigenetic targets in lymphoproliferative disorders
-
Delgado J. Novel epigenetic targets in lymphoproliferative disorders. Curr Cancer Drug Targets 8 5 (2008) 378-391
-
(2008)
Curr Cancer Drug Targets
, vol.8
, Issue.5
, pp. 378-391
-
-
Delgado, J.1
-
15
-
-
38049090238
-
Epigenetic clues to rheumatoid arthritis
-
Sanchez-Pernaute O., Ospelt C., Neidhart M., and Gay S. Epigenetic clues to rheumatoid arthritis. J Autoimmun 30 1-2 (2008) 12-20
-
(2008)
J Autoimmun
, vol.30
, Issue.1-2
, pp. 12-20
-
-
Sanchez-Pernaute, O.1
Ospelt, C.2
Neidhart, M.3
Gay, S.4
-
16
-
-
42649095663
-
Epigenetics in human autoimmunity. Epigenetics in autoimmunity - DNA methylation in systemic lupus erythematosus and beyond
-
Strickland F.M., and Richardson B.C. Epigenetics in human autoimmunity. Epigenetics in autoimmunity - DNA methylation in systemic lupus erythematosus and beyond. Autoimmunity 41 4 (2008) 278-286
-
(2008)
Autoimmunity
, vol.41
, Issue.4
, pp. 278-286
-
-
Strickland, F.M.1
Richardson, B.C.2
-
17
-
-
57049160500
-
Evaluating epigenetic landmarks in the brain of multiple sclerosis patients: a contribution to the current debate on disease pathogenesis
-
Casaccia-Bonnefil P., Pandozy G., and Mastronardi F. Evaluating epigenetic landmarks in the brain of multiple sclerosis patients: a contribution to the current debate on disease pathogenesis. Prog Neurobiol 86 4 (2008) 368-378
-
(2008)
Prog Neurobiol
, vol.86
, Issue.4
, pp. 368-378
-
-
Casaccia-Bonnefil, P.1
Pandozy, G.2
Mastronardi, F.3
-
18
-
-
58049204426
-
Epigenetics in multiple sclerosis susceptibility: difference in transgenerational risk localizes to the major histocompatibility complex
-
Chao M.J., Ramagopalan S.V., Herrera B.M., Lincoln M.R., Dyment D.A., Sadovnick A.D., et al. Epigenetics in multiple sclerosis susceptibility: difference in transgenerational risk localizes to the major histocompatibility complex. Hum Mol Genet 18 2 (2009) 261-266
-
(2009)
Hum Mol Genet
, vol.18
, Issue.2
, pp. 261-266
-
-
Chao, M.J.1
Ramagopalan, S.V.2
Herrera, B.M.3
Lincoln, M.R.4
Dyment, D.A.5
Sadovnick, A.D.6
-
19
-
-
0036898622
-
p16(INK4A) Hypermethylation detected by fluorescent methylation-specific PCR in plasmas from non-small cell lung cancer
-
Bearzatto A., Conte D., Frattini M., Zaffaroni N., Andriani F., Balestra D., et al. p16(INK4A) Hypermethylation detected by fluorescent methylation-specific PCR in plasmas from non-small cell lung cancer. Clin Cancer Res 8 12 (2002) 3782-3787
-
(2002)
Clin Cancer Res
, vol.8
, Issue.12
, pp. 3782-3787
-
-
Bearzatto, A.1
Conte, D.2
Frattini, M.3
Zaffaroni, N.4
Andriani, F.5
Balestra, D.6
-
20
-
-
0016764251
-
Spontaneous release of DNA by human blood lymphocytes as shown in an in vitro system
-
Anker P., Stroun M., and Maurice P.A. Spontaneous release of DNA by human blood lymphocytes as shown in an in vitro system. Cancer Res 35 9 (1975) 2375-2382
-
(1975)
Cancer Res
, vol.35
, Issue.9
, pp. 2375-2382
-
-
Anker, P.1
Stroun, M.2
Maurice, P.A.3
-
21
-
-
0017360626
-
Free DNA in the serum of cancer patients and the effect of therapy
-
Leon S.A., Shapiro B., Sklaroff D.M., and Yaros M.J. Free DNA in the serum of cancer patients and the effect of therapy. Cancer Res 37 3 (1977) 646-650
-
(1977)
Cancer Res
, vol.37
, Issue.3
, pp. 646-650
-
-
Leon, S.A.1
Shapiro, B.2
Sklaroff, D.M.3
Yaros, M.J.4
-
22
-
-
0034020737
-
Plasma DNA as a prognostic marker in trauma patients
-
Lo Y.M., Rainer T.H., Chan L.Y., Hjelm N.M., and Cocks R.A. Plasma DNA as a prognostic marker in trauma patients. Clin Chem 46 3 (2000) 319-323
-
(2000)
Clin Chem
, vol.46
, Issue.3
, pp. 319-323
-
-
Lo, Y.M.1
Rainer, T.H.2
Chan, L.Y.3
Hjelm, N.M.4
Cocks, R.A.5
-
23
-
-
0037381516
-
Prognostic use of circulating plasma nucleic acid concentrations in patients with acute stroke
-
Rainer T.H., Wong L.K., Lam W., Yuen E., Lam N.Y., Metreweli C., et al. Prognostic use of circulating plasma nucleic acid concentrations in patients with acute stroke. Clin Chem 49 4 (2003) 562-569
-
(2003)
Clin Chem
, vol.49
, Issue.4
, pp. 562-569
-
-
Rainer, T.H.1
Wong, L.K.2
Lam, W.3
Yuen, E.4
Lam, N.Y.5
Metreweli, C.6
-
24
-
-
58849140824
-
Differential methylation profile of ovarian cancer in tissues and plasma
-
Melnikov A., Scholtens D., Godwin A., and Levenson V. Differential methylation profile of ovarian cancer in tissues and plasma. J Mol Diagn 11 1 (2009) 60-65
-
(2009)
J Mol Diagn
, vol.11
, Issue.1
, pp. 60-65
-
-
Melnikov, A.1
Scholtens, D.2
Godwin, A.3
Levenson, V.4
-
25
-
-
59649129034
-
Methylation profile of circulating plasma DNA in patients with pancreatic cancer
-
Melnikov A.A., Scholtens D., Talamonti M.S., Bentrem D.J., and Levenson V.V. Methylation profile of circulating plasma DNA in patients with pancreatic cancer. J Surg Oncol 99 2 (2009) 119-122
-
(2009)
J Surg Oncol
, vol.99
, Issue.2
, pp. 119-122
-
-
Melnikov, A.A.1
Scholtens, D.2
Talamonti, M.S.3
Bentrem, D.J.4
Levenson, V.V.5
-
26
-
-
0031815875
-
Cell-free DNA in human blood plasma: length measurements in patients with pancreatic cancer and healthy controls
-
Giacona M.B., Ruben G.C., Iczkowski K.A., Roos T.B., Porter D.M., and Sorenson G.D. Cell-free DNA in human blood plasma: length measurements in patients with pancreatic cancer and healthy controls. Pancreas 17 1 (1998) 89-97
-
(1998)
Pancreas
, vol.17
, Issue.1
, pp. 89-97
-
-
Giacona, M.B.1
Ruben, G.C.2
Iczkowski, K.A.3
Roos, T.B.4
Porter, D.M.5
Sorenson, G.D.6
-
27
-
-
70149099610
-
Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context
-
Christensen B.C., Houseman E.A., Marsit C.J., Zheng S., Wrensch M.R., Wiemels J.L., et al. Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context. PLoS Genet 5 8 (2009) e1000602
-
(2009)
PLoS Genet
, vol.5
, Issue.8
-
-
Christensen, B.C.1
Houseman, E.A.2
Marsit, C.J.3
Zheng, S.4
Wrensch, M.R.5
Wiemels, J.L.6
-
28
-
-
2442592788
-
Toll-like receptor ligands directly promote activated CD4+ T cell survival
-
Gelman A.E., Zhang J., Choi Y., and Turka L.A. Toll-like receptor ligands directly promote activated CD4+ T cell survival. J Immunol 172 10 (2004) 6065-6073
-
(2004)
J Immunol
, vol.172
, Issue.10
, pp. 6065-6073
-
-
Gelman, A.E.1
Zhang, J.2
Choi, Y.3
Turka, L.A.4
-
29
-
-
33846123950
-
Expression and function of Toll-like receptors in T lymphocytes
-
Kabelitz D. Expression and function of Toll-like receptors in T lymphocytes. Curr Opin Immunol 19 1 (2007) 39-45
-
(2007)
Curr Opin Immunol
, vol.19
, Issue.1
, pp. 39-45
-
-
Kabelitz, D.1
-
30
-
-
28544449709
-
Immune stimulation mediated by autoantigen binding sites within small nuclear RNAs involves Toll-like receptors 7 and 8
-
Vollmer J., Tluk S., Schmitz C., Hamm S., Jurk M., Forsbach A., et al. Immune stimulation mediated by autoantigen binding sites within small nuclear RNAs involves Toll-like receptors 7 and 8. J Exp Med 202 11 (2005) 1575-1585
-
(2005)
J Exp Med
, vol.202
, Issue.11
, pp. 1575-1585
-
-
Vollmer, J.1
Tluk, S.2
Schmitz, C.3
Hamm, S.4
Jurk, M.5
Forsbach, A.6
-
31
-
-
0037061453
-
Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors
-
Leadbetter E.A., Rifkin I.R., Hohlbaum A.M., Beaudette B.C., Shlomchik M.J., and Marshak-Rothstein A. Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors. Nature 416 6881 (2002) 603-607
-
(2002)
Nature
, vol.416
, Issue.6881
, pp. 603-607
-
-
Leadbetter, E.A.1
Rifkin, I.R.2
Hohlbaum, A.M.3
Beaudette, B.C.4
Shlomchik, M.J.5
Marshak-Rothstein, A.6
-
32
-
-
69149104967
-
Toll-like receptor expression and function in subsets of human gammadelta T lymphocytes
-
Pietschmann K., Beetz S., Welte S., Martens I., Gruen J., Oberg H.H., et al. Toll-like receptor expression and function in subsets of human gammadelta T lymphocytes. Scand J Immunol 70 3 (2009) 245-255
-
(2009)
Scand J Immunol
, vol.70
, Issue.3
, pp. 245-255
-
-
Pietschmann, K.1
Beetz, S.2
Welte, S.3
Martens, I.4
Gruen, J.5
Oberg, H.H.6
-
33
-
-
25444443335
-
RNA released from necrotic synovial fluid cells activates rheumatoid arthritis synovial fibroblasts via Toll-like receptor 3
-
Brentano F., Schorr O., Gay R.E., Gay S., and Kyburz D. RNA released from necrotic synovial fluid cells activates rheumatoid arthritis synovial fibroblasts via Toll-like receptor 3. Arthritis Rheum 52 9 (2005) 2656-2665
-
(2005)
Arthritis Rheum
, vol.52
, Issue.9
, pp. 2656-2665
-
-
Brentano, F.1
Schorr, O.2
Gay, R.E.3
Gay, S.4
Kyburz, D.5
-
34
-
-
70449717532
-
TLR3 ligand polyinosinic:polycytidylic acid induces IL-17A and IL-21 synthesis in human Th cells
-
Holm C.K., Petersen C.C., Hvid M., Petersen L., Paludan S.R., Deleuran B., et al. TLR3 ligand polyinosinic:polycytidylic acid induces IL-17A and IL-21 synthesis in human Th cells. J Immunol 183 7 (2009) 4422-4431
-
(2009)
J Immunol
, vol.183
, Issue.7
, pp. 4422-4431
-
-
Holm, C.K.1
Petersen, C.C.2
Hvid, M.3
Petersen, L.4
Paludan, S.R.5
Deleuran, B.6
-
35
-
-
43349094856
-
Up-regulated expression of Toll-like receptors mRNAs in peripheral blood mononuclear cells from patients with systemic lupus erythematosus
-
Komatsuda A., Wakui H., Iwamoto K., Ozawa M., Togashi M., Masai R., et al. Up-regulated expression of Toll-like receptors mRNAs in peripheral blood mononuclear cells from patients with systemic lupus erythematosus. Clin Exp Immunol 152 3 (2008) 482-487
-
(2008)
Clin Exp Immunol
, vol.152
, Issue.3
, pp. 482-487
-
-
Komatsuda, A.1
Wakui, H.2
Iwamoto, K.3
Ozawa, M.4
Togashi, M.5
Masai, R.6
-
36
-
-
38649102170
-
Role of pathogenic auto-antibody production by Toll-like receptor 9 of B cells in active systemic lupus erythematosus
-
Nakano S., Morimoto S., Suzuki J., Nozawa K., Amano H., Tokano Y., et al. Role of pathogenic auto-antibody production by Toll-like receptor 9 of B cells in active systemic lupus erythematosus. Rheumatology (Oxford) 47 2 (2008) 145-149
-
(2008)
Rheumatology (Oxford)
, vol.47
, Issue.2
, pp. 145-149
-
-
Nakano, S.1
Morimoto, S.2
Suzuki, J.3
Nozawa, K.4
Amano, H.5
Tokano, Y.6
-
37
-
-
32444443739
-
Innate immunity mediated by TLR9 modulates pathogenicity in an animal model of multiple sclerosis
-
Prinz M., Garbe F., Schmidt H., Mildner A., Gutcher I., Wolter K., et al. Innate immunity mediated by TLR9 modulates pathogenicity in an animal model of multiple sclerosis. J Clin Invest 116 2 (2006) 456-464
-
(2006)
J Clin Invest
, vol.116
, Issue.2
, pp. 456-464
-
-
Prinz, M.1
Garbe, F.2
Schmidt, H.3
Mildner, A.4
Gutcher, I.5
Wolter, K.6
-
38
-
-
17844383756
-
Inhibitors of TLR-9 act on multiple cell subsets in mouse and man in vitro and prevent death in vivo from systemic inflammation
-
Duramad O., Fearon K.L., Chang B., Chan J.H., Gregorio J., Coffman R.L., et al. Inhibitors of TLR-9 act on multiple cell subsets in mouse and man in vitro and prevent death in vivo from systemic inflammation. J Immunol 174 9 (2005) 5193-5200
-
(2005)
J Immunol
, vol.174
, Issue.9
, pp. 5193-5200
-
-
Duramad, O.1
Fearon, K.L.2
Chang, B.3
Chan, J.H.4
Gregorio, J.5
Coffman, R.L.6
-
39
-
-
56549093441
-
Toll-like receptors in autoimmunity
-
Fischer M., and Ehlers M. Toll-like receptors in autoimmunity. Ann N Y Acad Sci 1143 (2008) 21-34
-
(2008)
Ann N Y Acad Sci
, vol.1143
, pp. 21-34
-
-
Fischer, M.1
Ehlers, M.2
-
40
-
-
33244495503
-
Multiple toll-like receptor agonists act as potent adjuvants in the induction of autoimmunity
-
Hansen B.S., Hussain R.Z., Lovett-Racke A.E., Thomas J.A., and Racke M.K. Multiple toll-like receptor agonists act as potent adjuvants in the induction of autoimmunity. J Neuroimmunol 172 1-2 (2006) 94-103
-
(2006)
J Neuroimmunol
, vol.172
, Issue.1-2
, pp. 94-103
-
-
Hansen, B.S.1
Hussain, R.Z.2
Lovett-Racke, A.E.3
Thomas, J.A.4
Racke, M.K.5
-
41
-
-
35748964708
-
Toll-like receptors 7, 8, and 9: linking innate immunity to autoimmunity
-
Krieg A.M., and Vollmer J. Toll-like receptors 7, 8, and 9: linking innate immunity to autoimmunity. Immunol Rev 220 (2007) 251-269
-
(2007)
Immunol Rev
, vol.220
, pp. 251-269
-
-
Krieg, A.M.1
Vollmer, J.2
-
42
-
-
38749121383
-
Array-based multiplex analysis of DNA methylation in breast cancer tissues
-
Melnikov A.A., Scholtens D.M., Wiley E.L., Khan S.A., and Levenson V.V. Array-based multiplex analysis of DNA methylation in breast cancer tissues. J Mol Diagn 10 1 (2008) 93-101
-
(2008)
J Mol Diagn
, vol.10
, Issue.1
, pp. 93-101
-
-
Melnikov, A.A.1
Scholtens, D.M.2
Wiley, E.L.3
Khan, S.A.4
Levenson, V.V.5
-
43
-
-
77950211367
-
Differential methylation of cell-free circulating DNA in patients with pancreatic cancer and chronic pancreatitis
-
in press
-
Liggett T, Melnikov A, Yi Q, Replogle C, Brand R, Kaul K, Talamonti M, Abrams R, Levenson V. Differential methylation of cell-free circulating DNA in patients with pancreatic cancer and chronic pancreatitis. Cancer. in press.
-
Cancer
-
-
Liggett, T.1
Melnikov, A.2
Yi, Q.3
Replogle, C.4
Brand, R.5
Kaul, K.6
Talamonti, M.7
Abrams, R.8
Levenson, V.9
|