-
1
-
-
0037472924
-
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
-
DOI 10.1038/nature01368
-
Bakkenist CJ and Kastan MB: DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature 421: 499-506, 2003. (Pubitemid 36168436)
-
(2003)
Nature
, vol.421
, Issue.6922
, pp. 499-506
-
-
Bakkenist, C.J.1
Kastan, M.B.2
-
2
-
-
0037472915
-
DNA repair: Damage alert
-
DOI 10.1038/421486a
-
Bartek J and Lukas J: DNA repair: damage alert. Nature 421: 486-488, 2003. (Pubitemid 36168427)
-
(2003)
Nature
, vol.421
, Issue.6922
, pp. 486-488
-
-
Bartek, J.1
Lukas, J.2
-
3
-
-
0035902108
-
Genome maintenance mechanisms for preventing cancer
-
Hoeijmakers JH: Genome maintenance mechanisms for preventing cancer. Nature 411: 366-374, 2001.
-
(2001)
Nature
, vol.411
, pp. 366-374
-
-
Hoeijmakers, J.H.1
-
4
-
-
0037365789
-
ATM and related protein kinases: Safeguarding genome integrity
-
Shiloh Y: ATM and related protein kinases: safeguarding genome integrity. Nat Rev Cancer 3: 155-168, 2003.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 155-168
-
-
Shiloh, Y.1
-
5
-
-
0032489520
-
DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
-
DOI 10.1074/jbc.273.10.5858
-
Rogakou EP, Pilch DR, Orr AH, Ivanova VS and Bonner WM: DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J Biol Chem 273: 5858-5868, 1998. (Pubitemid 28124064)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.10
, pp. 5858-5868
-
-
Rogakou, E.P.1
Pilch, D.R.2
Orr, A.H.3
Ivanova, V.S.4
Bonner, W.M.5
-
6
-
-
0032861343
-
Megabase chromatin domains involved in DNA double-strand breaks in vivo
-
Rogakou EP, Boon C, Redon C and Bonner WM: Megabase chromatin domains involved in DNA double-strand breaks in vivo. J Cell Biol 146: 905-916, 1999.
-
(1999)
J Cell Biol
, vol.146
, pp. 905-916
-
-
Rogakou, E.P.1
Boon, C.2
Redon, C.3
Bonner, W.M.4
-
8
-
-
0042242630
-
Expression of phosphorylated histone H2AX in cultured cell lines following exposure to X-rays
-
DOI 10.1080/0955300032000093128
-
MacPhail SH, Banath JP, Yu TY, Chu EH, Lambur H and Olive PL: Expression of phosphorylated histone H2AX in cultured cell lines following exposure to X-rays. Int J Radiat Biol 79: 351-358, 2003. (Pubitemid 36920536)
-
(2003)
International Journal of Radiation Biology
, vol.79
, Issue.5
, pp. 351-358
-
-
Macphail, S.H.1
Banath, J.P.2
Yu, T.Y.3
Chu, E.H.M.4
Lambur, H.5
Olive, P.L.6
-
9
-
-
4944234150
-
Radiation sensitivity, H2AX phosphorylation, and kinetics of repair of DNA strand breaks in irradiated cervical cancer cell lines
-
DOI 10.1158/0008-5472.CAN-04-1433
-
Banath JP, Macphail SH and Olive PL: Radiation sensitivity, H2AX phosphorylation, and kinetics of repair of DNA strand breaks in irradiated cervical cancer cell lines. Cancer Res 64: 7144-7149, 2004. (Pubitemid 39331029)
-
(2004)
Cancer Research
, vol.64
, Issue.19
, pp. 7144-7149
-
-
Banath, J.P.1
MacPhail, S.H.2
Olive, P.L.3
-
10
-
-
3242880238
-
H2AX: The histone guardian of the genome
-
DOI 10.1016/j.dnarep.2004.03.024, PII S1568786404000837
-
Fernandez-Capetillo O, Lee A, Nussenzweig M and Nussenzweig A: H2AX: the histone guardian of the genome. DNA Repair (Amst) 3: 959-967, 2004. (Pubitemid 38997938)
-
(2004)
DNA Repair
, vol.3
, Issue.8-9
, pp. 959-967
-
-
Fernandez-Capetillo, O.1
Lee, A.2
Nussenzweig, M.3
Nussenzweig, A.4
-
11
-
-
0037341599
-
Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage
-
DOI 10.1038/ncb945
-
Lukas C, Falck J, Bartkova J, Bartek J and Lukas J: Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage. Nat Cell Biol 5: 255-260, 2003. (Pubitemid 36322254)
-
(2003)
Nature Cell Biology
, vol.5
, Issue.3
, pp. 255-260
-
-
Lukas, C.1
Falck, J.2
Bartkova, J.3
Bartek, J.4
Lukas, J.5
-
12
-
-
3342915628
-
Mdc1 couples DNA double-strand break recognition by Nbs1 with its H2AX-dependent chromatin retention
-
DOI 10.1038/sj.emboj.7600269
-
Lukas C, Melander F, Stucki M, et al: Mdc1 couples DNA double-strand break recognition by Nbs1 with its H2AX-dependent chromatin retention. EMBO J 23: 2674-2683, 2004. (Pubitemid 38988238)
-
(2004)
EMBO Journal
, vol.23
, Issue.13
, pp. 2674-2683
-
-
Lukas, C.1
Melander, F.2
Stucki, M.3
Falck, J.4
Bekker-Jensen, S.5
Goldberg, M.6
Lerenthal, Y.7
Jackson, S.P.8
Bartek, J.9
Lukas, J.10
-
13
-
-
36248966246
-
RNF8 Ubiquitylates Histones at DNA Double-Strand Breaks and Promotes Assembly of Repair Proteins
-
DOI 10.1016/j.cell.2007.09.040, PII S0092867407012718
-
Mailand N, Bekker-Jensen S, Faustrup H, et al: RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins. Cell 131: 887-900, 2007. (Pubitemid 350138084)
-
(2007)
Cell
, vol.131
, Issue.5
, pp. 887-900
-
-
Mailand, N.1
Bekker-Jensen, S.2
Faustrup, H.3
Melander, F.4
Bartek, J.5
Lukas, C.6
Lukas, J.7
-
14
-
-
33646117239
-
Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks
-
Bekker-Jensen S, Lukas C, Kitagawa R, et al: Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks. J Cell Biol 173: 195-206, 2006.
-
(2006)
J Cell Biol
, vol.173
, pp. 195-206
-
-
Bekker-Jensen, S.1
Lukas, C.2
Kitagawa, R.3
-
15
-
-
33845627082
-
Cellular responses to DNA damage: One signal, multiple choices
-
Su TT: Cellular responses to DNA damage: one signal, multiple choices. Annu Rev Genet 40: 187-208, 2006.
-
(2006)
Annu Rev Genet
, vol.40
, pp. 187-208
-
-
Su, T.T.1
-
16
-
-
0028575336
-
Radiation-induced apoptosis in sensitive and resistant cells isolated from a mouse lymphoma
-
Story MD, Voehringer DW, Malone CG, Hobbs ML and Meyn RE: Radiation-induced apoptosis in sensitive and resistant cells isolated from a mouse lymphoma. Int J Radiat Biol 66: 659-668, 1994.
-
(1994)
Int J Radiat Biol
, vol.66
, pp. 659-668
-
-
Story, M.D.1
Voehringer, D.W.2
Malone, C.G.3
Hobbs, M.L.4
Meyn, R.E.5
-
17
-
-
0027285362
-
Lethality induced by a single site-specific double-strand break in a dispensable yeast plasmid
-
Bennett CB, Lewis AL, Baldwin KK and Resnick MA: Lethality induced by a single site-specific double-strand break in a dispensable yeast plasmid. Proc Natl Acad Sci USA 90: 5613-5617, 1993. (Pubitemid 23176211)
-
(1993)
Proceedings of the National Academy of Sciences of the United States of America
, vol.90
, Issue.12
, pp. 5613-5617
-
-
Bennett, C.B.1
Lewis, A.L.2
Baldwin, K.K.3
Resnick, M.A.4
-
18
-
-
1942534150
-
Assessment of Histone H2AX Phosphorylation Induced by DNA Topoisomerase I and II Inhibitors Topotecan and Mitoxantrone and by the DNA Cross-Linking Agent Cisplatin
-
Huang X, Okafuji M, Traganos F, Luther E, Holden E and Darzynkiewicz Z: Assessment of histone H2AX phosphorylation induced by DNA topoisomerase I and II inhibitors topotecan and mitoxantrone and by the DNA cross-linking agent cisplatin. Cytometry A 58: 99-110, 2004. (Pubitemid 38509171)
-
(2004)
Cytometry Part A
, vol.58
, Issue.2
, pp. 99-110
-
-
Huang, X.1
Okafuji, M.2
Traganos, F.3
Luther, E.4
Holden, E.5
Darzynkiewicz, Z.6
-
19
-
-
74049110106
-
High content image cytometry in the context of subnuclear organization
-
De Vos WH, Van Neste L, Dieriks B, Joss GH and Van Oostveldt P: High content image cytometry in the context of subnuclear organization. Cytometry A 77: 64-75, 2010.
-
(2010)
Cytometry A
, vol.77
, pp. 64-75
-
-
De Vos, W.H.1
Van Neste, L.2
Dieriks, B.3
Joss, G.H.4
Van Oostveldt, P.5
-
20
-
-
0037092177
-
Use of CD45 gating in three and four-color flow cytometric immunophenotyping: Guideline from the National Institute of Allergy and Infectious Diseases, Division of AIDS
-
Schnizlein-Bick CT, Mandy FF, O'Gorman MR, et al: Use of CD45 gating in three and four-color flow cytometric immunophenotyping: guideline from the National Institute of Allergy and Infectious Diseases, Division of AIDS. Cytometry 50: 46-52, 2002.
-
(2002)
Cytometry
, vol.50
, pp. 46-52
-
-
Schnizlein-Bick, C.T.1
Mandy, F.F.2
O'Gorman, M.R.3
-
21
-
-
0037092123
-
CD45-assisted PanLeucogating for accurate, cost-effective dual-platform CD4+ T-cell enumeration
-
Glencross D, Scott LE, Jani IV, Barnett D and Janossy G: CD45-assisted PanLeucogating for accurate, cost-effective dual-platform CD4+ T-cell enumeration. Cytometry 50: 69-77, 2002.
-
(2002)
Cytometry
, vol.50
, pp. 69-77
-
-
Glencross, D.1
Scott, L.E.2
Jani, I.V.3
Barnett, D.4
Janossy, G.5
-
23
-
-
77956292345
-
Dose response and repair kinetics of gamma-H2AX foci induced by in vitro irradiation of whole blood and T-lymphocytes with X- and gamma-radiation
-
Beels L, Werbrouck J and Thierens H: Dose response and repair kinetics of gamma-H2AX foci induced by in vitro irradiation of whole blood and T-lymphocytes with X- and gamma-radiation. Int J Radiat Biol 86: 760-768, 2010.
-
(2010)
Int J Radiat Biol
, vol.86
, pp. 760-768
-
-
Beels, L.1
Werbrouck, J.2
Thierens, H.3
-
24
-
-
33845606709
-
Leukocyte DNA damage after multi-detector row CT: A quantitative biomarker of low-level radiation exposure
-
DOI 10.1148/radiol.2421060171
-
Rothkamm K, Balroop S, Shekhdar J, Fernie P and Goh V: Leukocyte DNA damage after multi-detector row CT: a quantitative biomarker of low-level radiation exposure. Radiology 242: 244-251, 2007. (Pubitemid 44956030)
-
(2007)
Radiology
, vol.242
, Issue.1
, pp. 244-251
-
-
Rothkamm, K.1
Balroop, S.2
Shekhdar, J.3
Fernie, P.4
Goh, V.5
-
25
-
-
33748472075
-
Levels of gamma-H2AX foci after low-dose-rate irradiation reveal a DNA DSB rejoining defect in cells from human ATM heterozygotes in two AT families and in another apparently normal individual
-
DOI 10.1667/RR3604.1
-
Kato TA, Nagasawa H, Weil MM, Little JB and Bedford JS: Levels of gamma-H2AX Foci after low-dose-rate irradiation reveal a DNA DSB rejoining defect in cells from human ATM heterozygotes in two at families and in another apparently normal individual. Radiat Res 166: 443-453, 2006. (Pubitemid 44353427)
-
(2006)
Radiation Research
, vol.166
, Issue.3
, pp. 443-453
-
-
Kato, T.A.1
Nagasawa, H.2
Weil, M.M.3
Little, J.B.4
Bedford, J.S.5
-
26
-
-
39249083653
-
Comparison of the induction and disappearance of DNA double strand breaks and gamma-H2AX foci after irradiation of chromosomes in G1-phase or in condensed metaphase cells
-
Kato TA, Okayasu R and Bedford JS: Comparison of the induction and disappearance of DNA double strand breaks and gamma-H2AX foci after irradiation of chromosomes in G1-phase or in condensed metaphase cells. Mutat Res 639: 108-112, 2008.
-
(2008)
Mutat Res
, vol.639
, pp. 108-112
-
-
Kato, T.A.1
Okayasu, R.2
Bedford, J.S.3
-
27
-
-
33645144591
-
Induction and quantification of gamma-H2AX foci following low and high LET-irradiation
-
Leatherbarrow EL, Harper JV, Cucinotta FA and O'Neill P: Induction and quantification of gamma-H2AX foci following low and high LET-irradiation. Int J Radiat Biol 82: 111-118, 2006.
-
(2006)
Int J Radiat Biol
, vol.82
, pp. 111-118
-
-
Leatherbarrow, E.L.1
Harper, J.V.2
Cucinotta, F.A.3
O'Neill, P.4
-
29
-
-
47349107760
-
ATM Signaling Facilitates Repair of DNA Double-Strand Breaks Associated with Heterochromatin
-
DOI 10.1016/j.molcel.2008.05.017, PII S109727650800395X
-
Goodarzi AA, Noon AT, Deckbar D, et al: ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin. Mol Cell 31: 167-177, 2008. (Pubitemid 352001394)
-
(2008)
Molecular Cell
, vol.31
, Issue.2
, pp. 167-177
-
-
Goodarzi, A.A.1
Noon, A.T.2
Deckbar, D.3
Ziv, Y.4
Shiloh, Y.5
Lobrich, M.6
Jeggo, P.A.7
-
31
-
-
25444490915
-
Induction and repair of DNA double-strand breaks in human cells: Dephosphorylation of histone H2AX and its inhibition by calyculin A
-
DOI 10.1667/RR3379.1
-
Antonelli F, Belli M, Cuttone G, et al: Induction and repair of DNA double-strand breaks in human cells: dephosphorylation of histone H2AX and its inhibition by calyculin A. Radiat Res 164: 514-517, 2005. (Pubitemid 41368928)
-
(2005)
Radiation Research
, vol.164
, Issue.4 II
, pp. 514-517
-
-
Antonelli, F.1
Belli, M.2
Cuttone, G.3
Dini, V.4
Esposito, G.5
Simone, G.6
Sorrentino, E.7
Tabocchini, M.A.8
-
32
-
-
39749184636
-
Biochemical kinetics model of DSB repair and induction of gamma-H2AX foci by non-homologous end joining
-
DOI 10.1667/RR1035.1
-
Cucinotta FA, Pluth JM, Anderson JA, Harper JV and O'Neill P: Biochemical kinetics model of DSB repair and induction of gamma-H2AX foci by non-homologous end joining. Radiat Res 169: 214-222, 2008. (Pubitemid 351295079)
-
(2008)
Radiation Research
, vol.169
, Issue.2
, pp. 214-222
-
-
Cucinotta, F.A.1
Pluth, J.M.2
Anderson, J.A.3
Harper, J.V.4
O'Neill, P.5
-
33
-
-
38349134829
-
Delayed kinetics of DNA double-strand break processing in normal and pathological aging
-
Sedelnikova OA, Horikawa I, Redon C, et al: Delayed kinetics of DNA double-strand break processing in normal and pathological aging. Aging Cell 7: 89-100, 2008.
-
(2008)
Aging Cell
, vol.7
, pp. 89-100
-
-
Sedelnikova, O.A.1
Horikawa, I.2
Redon, C.3
-
34
-
-
77956460186
-
Use of gammaH2AX and other biomarkers of double-strand breaks during radiotherapy
-
Sak A and Stuschke M: Use of gammaH2AX and other biomarkers of double-strand breaks during radiotherapy. Semin Radiat Oncol 20: 223-231, 2010.
-
(2010)
Semin Radiat Oncol
, vol.20
, pp. 223-231
-
-
Sak, A.1
Stuschke, M.2
-
35
-
-
62949181960
-
Gamma-H2AX as a biomarker of DNA damage induced by ionizing radiation in human peripheral blood lymphocytes and artificial skin
-
Redon CE, Dickey JS, Bonner WM and Sedelnikova OA: Gamma-H2AX as a biomarker of DNA damage induced by ionizing radiation in human peripheral blood lymphocytes and artificial skin. Adv Space Res 43: 1171-1178, 2009.
-
(2009)
Adv Space Res
, vol.43
, pp. 1171-1178
-
-
Redon, C.E.1
Dickey, J.S.2
Bonner, W.M.3
Sedelnikova, O.A.4
-
36
-
-
77955158269
-
Quantification of gammaH2AX foci in human lymphocytes: A method for biological dosimetry after ionizing radiation exposure
-
Roch-Lefevre S, Mandina T, Voisin P, et al: Quantification of gammaH2AX foci in human lymphocytes: a method for biological dosimetry after ionizing radiation exposure. Radiat Res 174: 185-194, 2010.
-
(2010)
Radiat Res
, vol.174
, pp. 185-194
-
-
Roch-Lefevre, S.1
Mandina, T.2
Voisin, P.3
-
37
-
-
0343280013
-
A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage
-
DOI 10.1016/S0960-9822(00)00610-2
-
Paull TT, Rogakou EP, Yamazaki V, Kirchgessner CU, Gellert M and Bonner WM: A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage. Curr Biol 10: 886-895, 2000. (Pubitemid 30647617)
-
(2000)
Current Biology
, vol.10
, Issue.15
, pp. 886-895
-
-
Paull, T.T.1
Rogakou, E.P.2
Yamazaki, V.3
Kirchgessner, C.U.4
Gellert, M.5
Bonner, W.M.6
-
38
-
-
0027976408
-
Initial events in the cellular effects of ionizing radiations: Clustered damage in DNA
-
Goodhead DT: Initial events in the cellular effects of ionizing radiations: clustered damage in DNA. Int J Radiat Biol 65: 7-17, 1994.
-
(1994)
Int J Radiat Biol
, vol.65
, pp. 7-17
-
-
Goodhead, D.T.1
-
39
-
-
0034753336
-
Computational approach for determining the spectrum of DNA damage induced by ionizing radiation
-
Nikjoo H, O'Neill P, Wilson WE and Goodhead DT: Computational approach for determining the spectrum of DNA damage induced by ionizing radiation. Radiat Res 156: 577-583, 2001. (Pubitemid 33027531)
-
(2001)
Radiation Research
, vol.156
, Issue.5 II
, pp. 577-583
-
-
Nikjoo, H.1
O'Neill, P.2
Wilson, W.E.3
Goodhead, D.T.4
-
40
-
-
0036682280
-
Clustered DNA damage induced by gamma radiation in human fibroblasts (HF19), hamster (V79-4) cells and plasmid DNA is revealed as Fpg and Nth sensitive sites
-
Gulston M, Fulford J, Jenner T, de Lara C and O'Neill P: Clustered DNA damage induced by gamma radiation in human fibroblasts (HF19), hamster (V79-4) cells and plasmid DNA is revealed as Fpg and Nth sensitive sites. Nucleic Acids Res 30: 3464-3472, 2002. (Pubitemid 34845943)
-
(2002)
Nucleic Acids Research
, vol.30
, Issue.15
, pp. 3464-3472
-
-
Gulston, M.1
Fulford, J.2
Jenner, T.3
De Lara, C.4
O'Neill, P.5
-
41
-
-
0034739853
-
p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks
-
DOI 10.1083/jcb.151.7.1381
-
Schultz LB, Chehab NH, Malikzay A and Halazonetis TD: p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks. J Cell Biol 151: 1381-1390, 2000. (Pubitemid 32047588)
-
(2000)
Journal of Cell Biology
, vol.151
, Issue.7
, pp. 1381-1390
-
-
Schultz, L.B.1
Chehab, N.H.2
Malikzay, A.3
Halazonetis, T.D.4
-
42
-
-
29244434544
-
MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks
-
DOI 10.1016/j.cell.2005.09.038, PII S0092867405011657
-
Stucki M, Clapperton JA, Mohammad D, Yaffe MB, Smerdon SJ and Jackson SP: MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks. Cell 123: 1213-1226, 2005. (Pubitemid 41821780)
-
(2005)
Cell
, vol.123
, Issue.7
, pp. 1213-1226
-
-
Stucki, M.1
Clapperton, J.A.2
Mohammad, D.3
Yaffe, M.B.4
Smerdon, S.J.5
Jackson, S.P.6
-
43
-
-
0141780833
-
NFBD1/MDC1 regulates ionizing radiation-induced focus formation by DNA checkpoint signaling and repair factors
-
DOI 10.1096/fj.03-0310com
-
Xu X and Stern DF: NFBD1/MDC1 regulates ionizing radiation-induced focus formation by DNA checkpoint signaling and repair factors. FASEB J 17: 1842-1848, 2003. (Pubitemid 37214778)
-
(2003)
FASEB Journal
, vol.17
, Issue.13
, pp. 1842-1848
-
-
Xu, X.1
Stern, D.F.2
-
44
-
-
33646106590
-
GammaH2AX and MDC1: Anchoring the DNA-damage-response machinery to broken chromosomes
-
Stucki M and Jackson SP: gammaH2AX and MDC1: anchoring the DNA-damage-response machinery to broken chromosomes. DNA Repair (Amst) 5: 534-543, 2006.
-
(2006)
DNA Repair (Amst)
, vol.5
, pp. 534-543
-
-
Stucki, M.1
Jackson, S.P.2
-
45
-
-
0032085295
-
The 3′ to 5′ exonuclease activity of Mre11 facilitates repair of DNA double-strand breaks
-
Paull TT and Gellert M: The 3′ to 5′ exonuclease activity of Mre11 facilitates repair of DNA double-strand breaks. Mol Cell 1: 969-979, 1998. (Pubitemid 128379258)
-
(1998)
Molecular Cell
, vol.1
, Issue.7
, pp. 969-979
-
-
Paull, T.T.1
Gellert, M.2
-
46
-
-
0037628777
-
Low-dose radiation: Thresholds, bystander effects, and adaptive responses
-
Bonner WM: Low-dose radiation: thresholds, bystander effects, and adaptive responses. Proc Natl Acad Sci USA 100: 4973-4975, 2003.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 4973-4975
-
-
Bonner, W.M.1
-
47
-
-
0041732381
-
Characteristics of gamma-H2AX foci at DNA double-strand breaks sites
-
DOI 10.1139/o03-042
-
Pilch DR, Sedelnikova OA, Redon C, Celeste A, Nussenzweig A and Bonner WM: Characteristics of gamma-H2AX foci at DNA double-strand breaks sites. Biochem Cell Biol 81: 123-129, 2003. (Pubitemid 37076234)
-
(2003)
Biochemistry and Cell Biology
, vol.81
, Issue.3
, pp. 123-129
-
-
Pilch, D.R.1
Sedelnikova, O.A.2
Redon, C.3
Celeste, A.4
Nussenzweig, A.5
Bonner, W.M.6
-
49
-
-
21144456719
-
In vivo formation and repair of DNA double-strand breaks after computed tomography examinations
-
DOI 10.1073/pnas.0501895102
-
Lobrich M, Rief N, Kuhne M, et al: In vivo formation and repair of DNA double-strand breaks after computed tomography examinations. Proc Natl Acad Sci USA 102: 8984-8989, 2005. (Pubitemid 40881065)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.25
, pp. 8984-8989
-
-
Lobrich, M.1
Rief, N.2
Kuhne, M.3
Heckmann, M.4
Fleckenstein, J.5
Rube, C.6
Uder, M.7
-
50
-
-
33846913205
-
Short-term culture and gammaH2AX flow cytometry determine differences in individual radiosensitivity in human peripheral T lymphocytes
-
DOI 10.1002/em.20273
-
Hamasaki K, Imai K, Nakachi K, Takahashi N, Komada Y and Kusunoki Y: Short-term culture and gammaH2AX flow cytometry determine differences in individual radiosensitivity in human peripheral T lymphocytes. Environ Mol Mutagen 48: 38-47, 2007. (Pubitemid 46238557)
-
(2007)
Environmental and Molecular Mutagenesis
, vol.48
, Issue.1
, pp. 38-47
-
-
Hamasaki, K.1
Imai, K.2
Nakachi, K.3
Takahashi, N.4
Kodama, Y.5
Kusunoki, Y.6
-
51
-
-
33745927130
-
Histone H2AX phosphorylation in normal human cells irradiated with focused ultrasoft X rays: Evidence for chromatin movement during repair
-
DOI 10.1667/RR3577.1
-
Hamada N, Schettino G, Kashino G, et al: Histone H2AX phosphorylation in normal human cells irradiated with focused ultrasoft X rays: evidence for chromatin movement during repair. Radiat Res 166: 31-38, 2006. (Pubitemid 44051223)
-
(2006)
Radiation Research
, vol.166
, Issue.1 I
, pp. 31-38
-
-
Hamada, N.1
Schettino, G.2
Kashino, G.3
Vaid, M.4
Suzuki, K.5
Kodama, S.6
Vojnovic, B.7
Folkard, M.8
Watanabe, M.9
Michael, B.D.10
Prise, K.M.11
-
52
-
-
0346457085
-
Histone H2AX Phosphorylation as a Predictor of Radiosensitivity and Target for Radiotherapy
-
DOI 10.1074/jbc.M310030200
-
Taneja N, Davis M, Choy JS, et al: Histone H2AX phosphorylation as a predictor of radiosensitivity and target for radiotherapy. J Biol Chem 279: 2273-2280, 2004. (Pubitemid 38084500)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.3
, pp. 2273-2280
-
-
Taneja, N.1
Davis, M.2
Choy, J.S.3
Beckett, M.A.4
Singh, R.5
Kron, S.J.6
Weichselbaum, R.R.7
-
53
-
-
0030872550
-
Rapid assay of intrinsic radiosensitivity based on apoptosis in human CD4 and CD8 T-lymphocytes
-
DOI 10.1016/S0360-3016(97)00038-2, PII S0360301697000382
-
Ozsahin M, Ozsahin H, Shi Y, Larsson B, Wurgler FE and Crompton NE: Rapid assay of intrinsic radiosensitivity based on apoptosis in human CD4 and CD8 T-lymphocytes. Int J Radiat Oncol Biol Phys 38: 429-440, 1997. (Pubitemid 27318661)
-
(1997)
International Journal of Radiation Oncology Biology Physics
, vol.38
, Issue.2
, pp. 429-440
-
-
Ozsahin, M.1
Ozsahin, H.2
Shi, Y.3
Larsson, B.4
Wurgler, F.E.5
Crompton, N.E.A.6
-
54
-
-
0029998124
-
Radiation-induced apoptosis in human lymphocytes: Potential as a biological dosimeter
-
Boreham DR, Gale KL, Maves SR, Walker JA and Morrison DP: Radiation-induced apoptosis in human lymphocytes: potential as a biological dosimeter. Health Phys 71: 685-691, 1996. (Pubitemid 26346687)
-
(1996)
Health Physics
, vol.71
, Issue.5
, pp. 685-691
-
-
Boreham, D.R.1
Gale, K.L.2
Maves, S.R.3
Walker, J.-A.4
Morrison, D.P.5
-
55
-
-
0030959840
-
Flow cytometry as a quantitative and sensitive method to evaluate low dose radiation induced apoptosis in vitro in human peripheral blood lymphocytes
-
Hertveldt K, Philippe J, Thierens H, Cornelissen M, Vral A and De Ridder L: Flow cytometry as a quantitative and sensitive method to evaluate low dose radiation induced apoptosis in vitro in human peripheral blood lymphocytes. Int J Radiat Biol 71: 429-433, 1997. (Pubitemid 27187399)
-
(1997)
International Journal of Radiation Biology
, vol.71
, Issue.4
, pp. 429-433
-
-
Hertveldt, K.1
Philippe, J.2
Thierens, H.3
Cornelissen, M.4
Vral, A.5
De Ridder, L.6
-
56
-
-
0029132654
-
In vivo induction of apoptosis in human lymphocytes by therapeutic fractionated total body irradiation
-
Delic J, Magdelenat H, Barbaroux C, et al: In vivo induction of apoptosis in human lymphocytes by therapeutic fractionated total body irradiation. Br J Radiol 68: 997-1003, 1995.
-
(1995)
Br J Radiol
, vol.68
, pp. 997-1003
-
-
Delic, J.1
Magdelenat, H.2
Barbaroux, C.3
-
57
-
-
0031794286
-
Molecular mechanisms of DNA double-strand break repair
-
DOI 10.1016/S0962-8924(98)01383-X, PII S0962892498013816
-
Kanaar R, Hoeijmakers JH and van Gent DC: Molecular mechanisms of DNA double strand break repair. Trends Cell Biol 8: 483-489, 1998. (Pubitemid 28539407)
-
(1998)
Trends in Cell Biology
, vol.8
, Issue.12
, pp. 483-489
-
-
Kanaar, R.1
Hoeijmakers, J.H.J.2
Van Gent, D.C.3
-
58
-
-
0025325123
-
The circadian rhythm for the number and sensitivity of radiation-induced apoptosis in the crypts of mouse small intestine
-
Ijiri K and Potten CS: The circadian rhythm for the number and sensitivity of radiation-induced apoptosis in the crypts of mouse small intestine. Int J Radiat Biol 58: 165-175, 1990. (Pubitemid 20216902)
-
(1990)
International Journal of Radiation Biology
, vol.58
, Issue.1
, pp. 165-175
-
-
Ijiri, K.1
Potten, C.S.2
-
59
-
-
0026388063
-
Apoptosis in irradiated murine tumors
-
Stephens LC, Ang KK, Schultheiss TE, Milas L and Meyn RE: Apoptosis in irradiated murine tumors. Radiat Res 127: 308-316, 1991.
-
(1991)
Radiat Res
, vol.127
, pp. 308-316
-
-
Stephens, L.C.1
Ang, K.K.2
Schultheiss, T.E.3
Milas, L.4
Meyn, R.E.5
-
60
-
-
0026740395
-
Effects of cycloheximide and actinomycin D on radiation-induced apoptotic cell death in the developing mouse cerebellum
-
Inouye M, Tamaru M and Kameyama Y: Effects of cycloheximide and actinomycin D on radiation-induced apoptotic cell death in the developing mouse cerebellum. Int J Radiat Biol 61: 669-674, 1992.
-
(1992)
Int J Radiat Biol
, vol.61
, pp. 669-674
-
-
Inouye, M.1
Tamaru, M.2
Kameyama, Y.3
-
61
-
-
0028925622
-
Modulation of radiation-induced apoptosis and G2/M block in murine T-lymphoma cells
-
Palayoor ST, Macklis RM, Bump EA and Coleman CN: Modulation of radiation-induced apoptosis and G2/M block in murine T-lymphoma cells. Radiat Res 141: 235-243, 1995.
-
(1995)
Radiat Res
, vol.141
, pp. 235-243
-
-
Palayoor, S.T.1
Macklis, R.M.2
Bump, E.A.3
Coleman, C.N.4
-
62
-
-
0027941827
-
Apoptosis induced at different dose rates: Implication for the shoulder region of cell survival curves
-
DOI 10.1016/0167-8140(94)90099-X
-
Ling CC, Chen CH and Li WX: Apoptosis induced at different dose rates: implication for the shoulder region of cell survival curves. Radiother Oncol 32: 129-136, 1994. (Pubitemid 24270734)
-
(1994)
Radiotherapy and Oncology
, vol.32
, Issue.2
, pp. 129-136
-
-
Ling, C.C.1
-
63
-
-
0028951125
-
Correlation of micronucleus and apoptosis assays with reproductive cell death
-
Abend M, Rhein A, Gilbertz KP, Blakely WF and Van Beuningen D: Correlation of micronucleus and apoptosis assays with reproductive cell death. Int J Radiat Biol 67: 315-326, 1995.
-
(1995)
Int J Radiat Biol
, vol.67
, pp. 315-326
-
-
Abend, M.1
Rhein, A.2
Gilbertz, K.P.3
Blakely, W.F.4
Van Beuningen, D.5
-
64
-
-
0027479655
-
Dexamethasone-induced apoptosis involves cleavage of DNA to large fragments prior to internucleosomal fragmentation
-
Brown DG, Sun XM and Cohen GM: Dexamethasone-induced apoptosis involves cleavage of DNA to large fragments prior to internucleosomal fragmentation. J Biol Chem 268: 3037-3039, 1993. (Pubitemid 23070921)
-
(1993)
Journal of Biological Chemistry
, vol.268
, Issue.5
, pp. 3037-3039
-
-
Brown, D.G.1
Sun, X.-M.2
Cohen, G.M.3
-
65
-
-
0029808466
-
Cell cycle checkpoints: Preventing an identity crisis
-
Elledge SJ: Cell cycle checkpoints: preventing an identity crisis. Science 274: 1664-1672, 1996.
-
(1996)
Science
, vol.274
, pp. 1664-1672
-
-
Elledge, S.J.1
-
66
-
-
0345244825
-
P53-dependent apoptosis and transcription of p21(waf/cip1/sdi1) in SCID mice following gamma-irradiation
-
DOI 10.1016/S0300-9084(97)82010-X
-
Candeias SM, Durum SK and Muegge K: p53-dependent apoptosis and transcription of p21waf/cip1/sdi1 in SCID mice following gamma-irradiation. Biochimie 79: 607-612, 1997. (Pubitemid 28021569)
-
(1997)
Biochimie
, vol.79
, Issue.9-10
, pp. 607-612
-
-
Candeias, S.M.1
Durum, S.K.2
Muegge, K.3
-
67
-
-
0031463643
-
Cell death and longevity: Implications of Fas-mediated apoptosis in T-cell senescence
-
DOI 10.1111/j.1600-065X.1997.tb01024.x
-
Mountz JD, Wu J, Zhou T and Hsu HC: Cell death and longevity: implications of Fas-mediated apoptosis in T-cell senescence. Immunol Rev 160: 19-30, 1997. (Pubitemid 28021363)
-
(1997)
Immunological Reviews
, vol.160
, pp. 19-30
-
-
Mountz, J.D.1
Wu, J.2
Zhou, T.3
Hsu, H.-C.4
-
68
-
-
10144220637
-
Interleukin-1beta-converting enzyme-like protease cleaves DNA-dependent protein kinase in cytotoxic T cell killing
-
Song Q, Burrows SR, Smith G, et al: Interleukin-1 beta-converting enzyme-like protease cleaves DNA-dependent protein kinase in cytotoxic T cell killing. J Exp Med 184: 619-626, 1996. (Pubitemid 26324115)
-
(1996)
Journal of Experimental Medicine
, vol.184
, Issue.2
, pp. 619-626
-
-
Song, Q.1
Burrows, S.R.2
Smith, G.3
Lees-Miller, S.P.4
Kumar, S.5
Chan, D.W.6
Trapani, J.A.7
Alnemri, E.8
Litwack, G.9
Lu, H.10
Moss, D.J.11
Jackson, S.12
Lavin, M.F.13
-
70
-
-
0029085781
-
A checkpoint regulates the rate of progression through S phase in S. cerevisiae in response to DNA damage
-
Paulovich AG and Hartwell LH: A checkpoint regulates the rate of progression through S phase in S. cerevisiae in response to DNA damage. Cell 82: 841-847, 1995.
-
(1995)
Cell
, vol.82
, pp. 841-847
-
-
Paulovich, A.G.1
Hartwell, L.H.2
-
71
-
-
3242886503
-
Role of DNA-PK in the cellular response to DNA double-strand breaks
-
DOI 10.1016/j.dnarep.2004.03.021, PII S1568786404000801
-
Burma S and Chen DJ: Role of DNA-PK in the cellular response to DNA double-strand breaks. DNA Repair (Amst) 3: 909-918, 2004. (Pubitemid 38997932)
-
(2004)
DNA Repair
, vol.3
, Issue.8-9
, pp. 909-918
-
-
Burma, S.1
Chen, D.J.2
-
72
-
-
0036676638
-
Misrepair of radiation-induced DNA double-strand breaks and its relevance for tumorigenesis and cancer treatment
-
Review
-
Rothkamm K and Lobrich M: Misrepair of radiation-induced DNA double-strand breaks and its relevance for tumorigenesis and cancer treatment. (Review) Int J Oncol 21: 433-440, 2002.
-
(2002)
Int J Oncol
, vol.21
, pp. 433-440
-
-
Rothkamm, K.1
Lobrich, M.2
|