-
1
-
-
33747375410
-
Interaction of AMSH with ESCRT-III and deubiquitination of endosomal cargo
-
Agromayor, M. and Martin-Serrano, J. (2006). Interaction of AMSH with ESCRT-III and deubiquitination of endosomal cargo. J. Biol. Chem. 281, 1374-1387.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 1374-1387
-
-
Agromayor, M.1
Martin-Serrano, J.2
-
2
-
-
80054079071
-
Assembly and disassembly of the ESCRT-III membrane scission complex
-
Alonso, Y., Adell, M. and Teis, D. (2011). Assembly and disassembly of the ESCRT-III membrane scission complex. FEBS Lett. 585, 3191-3196.
-
(2011)
FEBS Lett
, vol.585
, pp. 3191-3196
-
-
Alonso, Y.1
Adell, M.2
Teis, D.3
-
3
-
-
0033786796
-
The DoA4 deubiquitinating enzyme is functionally linked to the vacuolar protein-sorting and endocytic pathways
-
Amerik, A. Y., Nowak, J., Swaminathan, S. and Hochstrasser, M. (2000). The DoA4 deubiquitinating enzyme is functionally linked to the vacuolar protein-sorting and endocytic pathways. Mol. Biol. Cell 11, 3365-3380.
-
(2000)
Mol. Biol. Cell
, vol.11
, pp. 3365-3380
-
-
Amerik, A.Y.1
Nowak, J.2
Swaminathan, S.3
Hochstrasser, M.4
-
4
-
-
33645714061
-
The KLH12-Cullin-3 ubiquitin ligase negatively regulates the Wnt-beta-catenin pathway by targeting Dishevelled for degradation
-
Angers, S., Thorpe, C. J., Bischele, T. L., Goldenberg, S. J., Zheng, N., MacCoss, M. J. and Moon, R. T. (2006). The KLH12-Cullin-3 ubiquitin ligase negatively regulates the Wnt-beta-catenin pathway by targeting Dishevelled for degradation. Nat. Cell Biol. 8, 348-357.
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 348-357
-
-
Angers, S.1
Thorpe, C.J.2
Bischele, T.L.3
Goldenberg, S.J.4
Zheng, N.5
MacCoss, M.J.6
Moon, R.T.7
-
5
-
-
79959847254
-
The role of deubiquitinating enzymes in chromatin regulation
-
Atanassov, B. S., Koutelou, E. and Dent, S. Y. (2011). The role of deubiquitinating enzymes in chromatin regulation. FEBS Lett. 585, 2016-2023.
-
(2011)
FEBS Lett
, vol.585
, pp. 2016-2023
-
-
Atanassov, B.S.1
Koutelou, E.2
Dent, S.Y.3
-
6
-
-
80355148474
-
Role of ubiquitylation and USP8-dependent deubiquitylation in the endocytosis and lysosomal targeting of plasma membrane KCa3.1.
-
Balut, C. M., Loch, C. M. and Devor, D. C. (2011). Role of ubiquitylation and USP8-dependent deubiquitylation in the endocytosis and lysosomal targeting of plasma membrane KCa3.1. FASEB J. 25, 3938-3948.
-
(2011)
FASEB J.
, vol.25
, pp. 3938-3948
-
-
Balut, C.M.1
Loch, C.M.2
Devor, D.C.3
-
7
-
-
80052697814
-
The ubiquitin- and SUMO-dependent signaling response to DNA double-strand breaks
-
Bekker-Jensen, S. and Mailand, N. (2011). The ubiquitin- and SUMO-dependent signaling response to DNA double-strand breaks. FEBS Lett. 585, 2914-2919.
-
(2011)
FEBS Lett
, vol.585
, pp. 2914-2919
-
-
Bekker-Jensen, S.1
Mailand, N.2
-
8
-
-
78549264851
-
The deubiquitinating enzyme USP8 promotes trafficking and degradation of the chemokine receptor 4 at the sorting endosome
-
Berlin, I., Higginbotham, K. M., Dise, R. S., Sierra, M. I. and Nash, P. D. (2010a). The deubiquitinating enzyme USP8 promotes trafficking and degradation of the chemokine receptor 4 at the sorting endosome. J. Biol. Chem. 285, 37895-37908.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 37895-37908
-
-
Berlin, I.1
Higginbotham, K.M.2
Dise, R.S.3
Sierra, M.I.4
Nash, P.D.5
-
9
-
-
78049404751
-
Regulation of epidermal growth factor receptor ubiquitination and trafficking by the USP8. STAM complex
-
Berlin, I., Schwartz, H. and Nash, P. D. (2010b). Regulation of epidermal growth factor receptor ubiquitination and trafficking by the USP8.STAM complex. J. Biol. Chem. 285, 34909-34921.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 34909-34921
-
-
Berlin, I.1
Schwartz, H.2
Nash, P.D.3
-
10
-
-
67649556158
-
The deubiquitinases USP33 and USP20 coordinate beta2 adrenergic receptor recycling and resensitization
-
Berthouze, M., Venkataramanan, V., Li, Y. and Shenoy, S. K. (2009). The deubiquitinases USP33 and USP20 coordinate beta2 adrenergic receptor recycling and resensitization. EMBO J. 28, 1684-1696.
-
(2009)
EMBO J
, vol.28
, pp. 1684-1696
-
-
Berthouze, M.1
Venkataramanan, V.2
Li, Y.3
Shenoy, S.K.4
-
11
-
-
77953902511
-
The deubiquitinating enzyme USP10 regulates the endocytic recycling of CFTR in airway epithelial cells
-
Bomberger, J. M., Barnaby, R. L. and Stanton, B. A. (2010). The deubiquitinating enzyme USP10 regulates the endocytic recycling of CFTR in airway epithelial cells. Channels (Austin) 4, 150-154.
-
(2010)
Channels (Austin)
, vol.4
, pp. 150-154
-
-
Bomberger, J.M.1
Barnaby, R.L.2
Stanton, B.A.3
-
12
-
-
57049188911
-
Vasopressin-inducible ubiquitinspecific protease 10 increases ENaC cell surface expression by deubiquitylating and stabilizing sorting nexin 3
-
Boulkroun, S., Ruffieux-Daidie, D., Vitagliano, J. J., Poirot, O., Charles, R. P., Lagnaz, D., Firsov, D., Kellenberger, S. and Staub, O. (2008). Vasopressin-inducible ubiquitinspecific protease 10 increases ENaC cell surface expression by deubiquitylating and stabilizing sorting nexin 3. Am. J. Physiol. Renal Physiol. 295, F889-F900.
-
(2008)
Am. J. Physiol. Renal Physiol.
, vol.295
-
-
Boulkroun, S.1
Ruffieux-Daidie, D.2
Vitagliano, J.J.3
Poirot, O.4
Charles, R.P.5
Lagnaz, D.6
Firsov, D.7
Kellenberger, S.8
Staub, O.9
-
13
-
-
33646171781
-
Degradation of endocytosed epidermal growth factor and virally ubiquitinated major histocompatibility complex class I is independent of mammalian ESCRTII
-
Bowers, K., Piper, S. C., Edeling, M. A., Gray, S. R., Owen, D. J., Lehner, P. J. and Luzio, J. P. (2006). Degradation of endocytosed epidermal growth factor and virally ubiquitinated major histocompatibility complex class I is independent of mammalian ESCRTII. J. Biol. Chem. 281, 5094-5105.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 5094-5105
-
-
Bowers, K.1
Piper, S.C.2
Edeling, M.A.3
Gray, S.R.4
Owen, D.J.5
Lehner, P.J.6
Luzio, J.P.7
-
14
-
-
77955417276
-
Lys11-linked ubiquitin chains adopt compact conformations and are preferentially hydrolyzed by the deubiquitinase Cezanne
-
Bremm, A., Freund, S. M. and Komander, D. (2010). Lys11-linked ubiquitin chains adopt compact conformations and are preferentially hydrolyzed by the deubiquitinase Cezanne. Nat. Struct. Mol. Biol. 17, 939-947.
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 939-947
-
-
Bremm, A.1
Freund, S.M.2
Komander, D.3
-
15
-
-
0042467554
-
Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB
-
Brummelkamp, T. R., Nijman, S. M., Dirac, A. M. and Bernards, R. (2003). Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB. Nature 424, 797-801.
-
(2003)
Nature
, vol.424
, pp. 797-801
-
-
Brummelkamp, T.R.1
Nijman, S.M.2
Dirac, A.M.3
Bernards, R.4
-
16
-
-
69949173205
-
Deubiquitinase activities required for hepatocyte growth factor-induced scattering of epithelial cells
-
Buus, R., Faronato, M., Hammond, D. E., Urbe, S. and Clague, M. J. (2009). Deubiquitinase activities required for hepatocyte growth factor-induced scattering of epithelial cells. Curr. Biol. 19, 1463-1466.
-
(2009)
Curr. Biol.
, vol.19
, pp. 1463-1466
-
-
Buus, R.1
Faronato, M.2
Hammond, D.E.3
Urbe, S.4
Clague, M.J.5
-
17
-
-
34347385894
-
Parallels between cytokinesis and retroviral budding: a role for the ESCRT machinery
-
Carlton, J. G. and Martin-Serrano, J. (2007). Parallels between cytokinesis and retroviral budding: a role for the ESCRT machinery. Science 316, 1908-1912.
-
(2007)
Science
, vol.316
, pp. 1908-1912
-
-
Carlton, J.G.1
Martin-Serrano, J.2
-
18
-
-
65249083913
-
Ubiquitin in NF-kappaB signaling
-
Chiu, Y. H., Zhao, M. and Chen, Z. J. (2009). Ubiquitin in NF-kappaB signaling. Chem. Rev. 109, 1549-1560.
-
(2009)
Chem. Rev.
, vol.109
, pp. 1549-1560
-
-
Chiu, Y.H.1
Zhao, M.2
Chen, Z.J.3
-
19
-
-
33750302074
-
Endocytosis: the DUB version
-
Clague, M. J. and Urbe, S. (2006). Endocytosis: the DUB version. Trends Cell Biol. 16, 551-559.
-
(2006)
Trends Cell Biol
, vol.16
, pp. 551-559
-
-
Clague, M.J.1
Urbe, S.2
-
20
-
-
78650100616
-
Ubiquitin: same molecule, different degradation pathways
-
Clague, M. J. and Urbe, S. (2010). Ubiquitin: same molecule, different degradation pathways. Cell 143, 682-685.
-
(2010)
Cell
, vol.143
, pp. 682-685
-
-
Clague, M.J.1
Urbe, S.2
-
21
-
-
36749082959
-
A UAF1-containing multisubunit protein complex regulates the Fanconi anemia pathway
-
Cohn, M. A., Kowal, P., Yang, K., Haas, W., Huang, T. T., Gygi, S. P. and D'Andrea, A. D. (2007). A UAF1-containing multisubunit protein complex regulates the Fanconi anemia pathway. Mol. Cell 28, 786-797.
-
(2007)
Mol. Cell
, vol.28
, pp. 786-797
-
-
Cohn, M.A.1
Kowal, P.2
Yang, K.3
Haas, W.4
Huang, T.T.5
Gygi, S.P.6
D'Andrea, A.D.7
-
22
-
-
62649104153
-
K63-specific deubiquitination by two JAMM/MPN+ complexes: BRISCassociated Brcc36 and proteasomal Poh1
-
Cooper, E. M., Cutcliffe, C., Kristiansen, T. Z., Pandey, A., Pickart, C. M. and Cohen, R. E. (2009). K63-specific deubiquitination by two JAMM/MPN+ complexes: BRISCassociated Brcc36 and proteasomal Poh1. EMBO J. 28, 621-631.
-
(2009)
EMBO J
, vol.28
, pp. 621-631
-
-
Cooper, E.M.1
Cutcliffe, C.2
Kristiansen, T.Z.3
Pandey, A.4
Pickart, C.M.5
Cohen, R.E.6
-
23
-
-
85047690484
-
Deubiquitination of type 2 iodothyronine deiodinase by von Hippel-Lindau protein-interacting deubiquitinating enzymes regulates thyroid hormone activation
-
Curcio-Morelli, C., Zavacki, A. M., Christofollete, M., Gereben, B., de Freitas, B. C., Harney, J. W., Li, Z., Wu, G. and Bianco, A. C. (2003). Deubiquitination of type 2 iodothyronine deiodinase by von Hippel-Lindau protein-interacting deubiquitinating enzymes regulates thyroid hormone activation. J. Clin. Invest. 112, 189-196.
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 189-196
-
-
Curcio-Morelli, C.1
Zavacki, A.M.2
Christofollete, M.3
Gereben, B.4
de Freitas, B.C.5
Harney, J.W.6
Li, Z.7
Wu, G.8
Bianco, A.C.9
-
24
-
-
79952101583
-
Early phase TGFbeta receptor signalling dynamics stabilised by the deubiquitinase UCH37 promotes cell migratory responses
-
Cutts, A. J., Soond, S. M., Powell, S. and Chantry, A. (2011). Early phase TGFbeta receptor signalling dynamics stabilised by the deubiquitinase UCH37 promotes cell migratory responses. Int. J. Biochem. Cell Biol. 43, 604-612.
-
(2011)
Int. J. Biochem. Cell Biol.
, vol.43
, pp. 604-612
-
-
Cutts, A.J.1
Soond, S.M.2
Powell, S.3
Chantry, A.4
-
25
-
-
38849110179
-
Targeting ubiquitin specific proteases for drug discovery
-
Daviet, L. and Colland, F. (2008). Targeting ubiquitin specific proteases for drug discovery. Biochimie 90, 270-283.
-
(2008)
Biochimie
, vol.90
, pp. 270-283
-
-
Daviet, L.1
Colland, F.2
-
26
-
-
70349441058
-
Ubiquitin-binding domains-from structures to functions
-
Dikic, I., Wakatsuki, S. and Walters, K. J. (2009). Ubiquitin-binding domains-from structures to functions. Nat. Rev. Mol. Cell Biol. 10, 659-671.
-
(2009)
Nat. Rev. Mol. Cell Biol.
, vol.10
, pp. 659-671
-
-
Dikic, I.1
Wakatsuki, S.2
Walters, K.J.3
-
27
-
-
79955985329
-
USP10 deubiquitylates the histone variant H2A, Z and both are required for androgen receptor-mediated gene activation
-
Draker, R., Sarcinella, E. and Cheung, P. (2011). USP10 deubiquitylates the histone variant H2A.Z and both are required for androgen receptor-mediated gene activation. Nucleic Acids Res. 39, 3529-3542.
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 3529-3542
-
-
Draker, R.1
Sarcinella, E.2
Cheung, P.3
-
28
-
-
78049510229
-
DNMT1 stability is regulated by proteins coordinating deubiquitination and acetylation-driven ubiquitination
-
Du, Z., Song, J., Wang, Y., Zhao, Y., Guda, K., Yang, S., Kao, H. Y., Xu, Y., Willis, J., Markowitz, S. D. et al. (2010). DNMT1 stability is regulated by proteins coordinating deubiquitination and acetylation-driven ubiquitination. Sci. Signal. 3, ra80.
-
(2010)
Sci. Signal.
, vol.3
-
-
Du, Z.1
Song, J.2
Wang, Y.3
Zhao, Y.4
Guda, K.5
Yang, S.6
Kao, H.Y.7
Xu, Y.8
Willis, J.9
Markowitz, S.D.10
-
29
-
-
33646147146
-
Lysine-63-linked ubiquitination is required for endolysosomal degradation of class I molecules
-
Duncan, L. M., Piper, S., Dodd, R. B., Saville, M. K., Sanderson, C. M., Luzio, J. P. and Lehner, P. J. (2006). Lysine-63-linked ubiquitination is required for endolysosomal degradation of class I molecules. EMBO J. 25, 1635-1645.
-
(2006)
EMBO J
, vol.25
, pp. 1635-1645
-
-
Duncan, L.M.1
Piper, S.2
Dodd, R.B.3
Saville, M.K.4
Sanderson, C.M.5
Luzio, J.P.6
Lehner, P.J.7
-
30
-
-
58149093172
-
FAM/USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination
-
Dupont, S., Mamidi, A., Cordenonsi, M., Montagner, M., Zacchigna, L., Adorno, M., Martello, G., Stinchfield, M. J., Soligo, S., Morsut, L. et al. (2009). FAM/USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination. Cell 136, 123-135.
-
(2009)
Cell
, vol.136
, pp. 123-135
-
-
Dupont, S.1
Mamidi, A.2
Cordenonsi, M.3
Montagner, M.4
Zacchigna, L.5
Adorno, M.6
Martello, G.7
Stinchfield, M.J.8
Soligo, S.9
Morsut, L.10
-
31
-
-
0034955239
-
Deubiquitination step in the endocytic pathway of yeast plasma membrane proteins: crucial role of Doa4p ubiquitin isopeptidase
-
Dupre, S. and Haguenauer-Tsapis, R. (2001). Deubiquitination step in the endocytic pathway of yeast plasma membrane proteins: crucial role of Doa4p ubiquitin isopeptidase. Mol. Cell. Biol. 21, 4482-4494.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 4482-4494
-
-
Dupre, S.1
Haguenauer-Tsapis, R.2
-
32
-
-
77649274212
-
Membrane contacts between endosomes and ER provide sites for PTP1B-epidermal growth factor receptor interaction
-
Eden, E. R., White, I. J., Tsapara, A. and Futter, C. E. (2010). Membrane contacts between endosomes and ER provide sites for PTP1B-epidermal growth factor receptor interaction. Nat. Cell Biol. 12, 267-272.
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 267-272
-
-
Eden, E.R.1
White, I.J.2
Tsapara, A.3
Futter, C.E.4
-
33
-
-
70349778618
-
The otubain YOD1 is a deubiquitinating enzyme that associates with p97 to facilitate protein dislocation from the ER
-
Ernst, R., Mueller, B., Ploegh, H. L. and Schlieker, C. (2009). The otubain YOD1 is a deubiquitinating enzyme that associates with p97 to facilitate protein dislocation from the ER. Mol. Cell 36, 28-38.
-
(2009)
Mol. Cell
, vol.36
, pp. 28-38
-
-
Ernst, R.1
Mueller, B.2
Ploegh, H.L.3
Schlieker, C.4
-
34
-
-
79953687692
-
Enzymatic blockade of the ubiquitin-proteasome pathway
-
Ernst, R., Claessen, J. H., Mueller, B., Sanyal, S., Spooner, E., van der Veen, A. G., Kirak, O., Schlieker, C. D., Weihofen, W. A. and Ploegh, H. L. (2011). Enzymatic blockade of the ubiquitin-proteasome pathway. PLoS Biol. 8, e1000605.
-
(2011)
PLoS Biol
, vol.8
-
-
Ernst, R.1
Claessen, J.H.2
Mueller, B.3
Sanyal, S.4
Spooner, E.5
van der Veen, A.G.6
Kirak, O.7
Schlieker, C.D.8
Weihofen, W.A.9
Ploegh, H.L.10
-
35
-
-
80052725628
-
The USP7/Dnmt1 complex stimulates the DNA methylation activity of Dnmt1 and regulates the stability of UHRF1
-
Felle, M., Joppien, S., Nemeth, A., Diermeier, S., Thalhammer, V., Dobner, T., Kremmer, E., Kappler, R. and Langst, G. (2011). The USP7/Dnmt1 complex stimulates the DNA methylation activity of Dnmt1 and regulates the stability of UHRF1. Nucleic Acids Res. 39, 8355-8365.
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 8355-8365
-
-
Felle, M.1
Joppien, S.2
Nemeth, A.3
Diermeier, S.4
Thalhammer, V.5
Dobner, T.6
Kremmer, E.7
Kappler, R.8
Langst, G.9
-
36
-
-
77957260099
-
The Lys63-specific deubiquitinating enzyme BRCC36 is regulated by two scaffold proteins localizing in different subcellular compartments
-
Feng, L., Wang, J. and Chen, J. (2010). The Lys63-specific deubiquitinating enzyme BRCC36 is regulated by two scaffold proteins localizing in different subcellular compartments. J. Biol. Chem. 285, 30982-30988.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 30982-30988
-
-
Feng, L.1
Wang, J.2
Chen, J.3
-
37
-
-
65649115267
-
Recognition and processing of ubiquitin-protein conjugates by the proteasome
-
Finley, D. (2009). Recognition and processing of ubiquitin-protein conjugates by the proteasome. Annu. Rev. Biochem. 78, 477-513.
-
(2009)
Annu. Rev. Biochem.
, vol.78
, pp. 477-513
-
-
Finley, D.1
-
38
-
-
80052694448
-
Dynamic regulation of PCNA ubiquitylation/deubiquitylation
-
Fox, J. T., Lee, K. Y. and Myung, K. (2011). Dynamic regulation of PCNA ubiquitylation/deubiquitylation. FEBS Lett. 585, 2780-2785.
-
(2011)
FEBS Lett
, vol.585
, pp. 2780-2785
-
-
Fox, J.T.1
Lee, K.Y.2
Myung, K.3
-
39
-
-
79953164696
-
Gene expression control by protein deubiquitinases
-
Frappier, L. and Verrijzer, C. P. (2011). Gene expression control by protein deubiquitinases. Curr. Opin. Genet. Dev. 21, 207-213.
-
(2011)
Curr. Opin. Genet. Dev.
, vol.21
, pp. 207-213
-
-
Frappier, L.1
Verrijzer, C.P.2
-
40
-
-
0030881952
-
Ubiquitin lys63 is involved in ubiquitination of a yeast plasma membrane protein
-
Galan, J. M. and Haguenauer-Tsapis, R. (1997). Ubiquitin lys63 is involved in ubiquitination of a yeast plasma membrane protein. EMBO J. 16, 5847-5854.
-
(1997)
EMBO J
, vol.16
, pp. 5847-5854
-
-
Galan, J.M.1
Haguenauer-Tsapis, R.2
-
41
-
-
77955172368
-
Autophagy negatively regulates Wnt signaling by promoting Dishevelled degradation
-
Gao, C., Cao, W., Bao, L., Zuo, W., Xie, G., Cai, T., Fu, W., Zhang, J., Wu, W., Zhang, X. et al. (2010). Autophagy negatively regulates Wnt signaling by promoting Dishevelled degradation. Nat. Cell Biol. 12, 781-790.
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 781-790
-
-
Gao, C.1
Cao, W.2
Bao, L.3
Zuo, W.4
Xie, G.5
Cai, T.6
Fu, W.7
Zhang, J.8
Wu, W.9
Zhang, X.10
-
42
-
-
21744433162
-
Ubp10/Dot4p regulates the persistence of ubiquitinated histone H2B: distinct roles in telomeric silencing and general chromatin
-
Gardner, R. G., Nelson, Z. W. and Gottschling, D. E. (2005). Ubp10/Dot4p regulates the persistence of ubiquitinated histone H2B: distinct roles in telomeric silencing and general chromatin. Mol. Cell. Biol. 25, 6123-6139.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 6123-6139
-
-
Gardner, R.G.1
Nelson, Z.W.2
Gottschling, D.E.3
-
43
-
-
79956027089
-
USP1 deubiquitinase maintains phosphorylated CHK1 by limiting its DDB1-dependent degradation
-
Guervilly, J. H., Renaud, E., Takata, M. and Rosselli, F. (2011). USP1 deubiquitinase maintains phosphorylated CHK1 by limiting its DDB1-dependent degradation. Hum. Mol. Genet. 20, 2171-2181.
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 2171-2181
-
-
Guervilly, J.H.1
Renaud, E.2
Takata, M.3
Rosselli, F.4
-
44
-
-
38149054804
-
Axin and GSK-β control Smad3 protein stability and modulate TGF-β signaling
-
Guo, X., Ramirez, A., Waddell, D. S., Li, Z., Liu, X. and Wang, X.-F. (2008). Axin and GSK-β control Smad3 protein stability and modulate TGF-β signaling. Genes Dev. 22, 106-120.
-
(2008)
Genes Dev
, vol.22
, pp. 106-120
-
-
Guo, X.1
Ramirez, A.2
Waddell, D.S.3
Li, Z.4
Liu, X.5
Wang, X.-F.6
-
45
-
-
78650915537
-
Deubiquitinases in the regulation of NF-kB signaling
-
Harhaj, E. W. and Dixit, V. M. (2011). Deubiquitinases in the regulation of NF-kB signaling. Cell Res. 21, 22-39.
-
(2011)
Cell Res
, vol.21
, pp. 22-39
-
-
Harhaj, E.W.1
Dixit, V.M.2
-
46
-
-
70350514475
-
Endosomal deubiquitinating enzymes control ubiquitination and down-regulation of proteaseactivated receptor 2
-
Hasdemir, B., Murphy, J. E., Cottrell, G. S. and Bunnett, N. W. (2009). Endosomal deubiquitinating enzymes control ubiquitination and down-regulation of proteaseactivated receptor 2. J. Biol. Chem. 284, 28453-28466.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 28453-28466
-
-
Hasdemir, B.1
Murphy, J.E.2
Cottrell, G.S.3
Bunnett, N.W.4
-
47
-
-
67650087753
-
The ER-resident ubiquitin-specific protease 19 participates in the UPR and rescues ERAD substrates
-
Hassink, G. C., Zhao, B., Sompallae, R., Altun, M., Gastaldello, S., Zinin, N. V., Masucci, M. G. and Lindsten, K. (2009). The ER-resident ubiquitin-specific protease 19 participates in the UPR and rescues ERAD substrates. EMBO Rep. 10, 755-761.
-
(2009)
EMBO Rep
, vol.10
, pp. 755-761
-
-
Hassink, G.C.1
Zhao, B.2
Sompallae, R.3
Altun, M.4
Gastaldello, S.5
Zinin, N.V.6
Masucci, M.G.7
Lindsten, K.8
-
48
-
-
63749105896
-
Mechanism of TGF-beta signaling to growth arrest, apoptosis, and epithelial-mesenchymal transition
-
Heldin, C. H., Landstrom, M. and Moustakas, A. (2009). Mechanism of TGF-beta signaling to growth arrest, apoptosis, and epithelial-mesenchymal transition. Curr. Opin. Cell Biol. 21, 166-176.
-
(2009)
Curr. Opin. Cell Biol.
, vol.21
, pp. 166-176
-
-
Heldin, C.H.1
Landstrom, M.2
Moustakas, A.3
-
49
-
-
79960225411
-
The ESCRT Pathway
-
Henne, W. M., Buchkovich, N. J. and Emr, S. D. (2011). The ESCRT Pathway. Dev. Cell 21, 77-91.
-
(2011)
Dev. Cell
, vol.21
, pp. 77-91
-
-
Henne, W.M.1
Buchkovich, N.J.2
Emr, S.D.3
-
51
-
-
0141442586
-
Regulation of membrane protein transport by ubiquitin and ubiquitin-binding proteins
-
Hicke, L. and Dunn, R. (2003). Regulation of membrane protein transport by ubiquitin and ubiquitin-binding proteins. Annu. Rev. Cell Dev. Biol. 19, 141-172.
-
(2003)
Annu. Rev. Cell Dev. Biol.
, vol.19
, pp. 141-172
-
-
Hicke, L.1
Dunn, R.2
-
52
-
-
33644852909
-
Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain
-
Huang, F., Kirkpatrick, D., Jiang, X., Gygi, S. and Sorkin, A. (2006a). Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain. Mol. Cell 21, 737-748.
-
(2006)
Mol. Cell
, vol.21
, pp. 737-748
-
-
Huang, F.1
Kirkpatrick, D.2
Jiang, X.3
Gygi, S.4
Sorkin, A.5
-
53
-
-
33645708319
-
Regulation of monoubiquitinated PCNA by DUB autocleavage
-
Huang, T. T., Nijman, S. M., Mirchandani, K. D., Galardy, P. J., Cohn, M. A., Haas, W., Gygi, S. P., Ploegh, H. L., Bernards, R. and D'Andrea, A. D. (2006b). Regulation of monoubiquitinated PCNA by DUB autocleavage. Nat. Cell Biol. 8, 339-347.
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 339-347
-
-
Huang, T.T.1
Nijman, S.M.2
Mirchandani, K.D.3
Galardy, P.J.4
Cohn, M.A.5
Haas, W.6
Gygi, S.P.7
Ploegh, H.L.8
Bernards, R.9
D'Andrea, A.D.10
-
54
-
-
68149160205
-
The COP9 signalosome mediates beta-catenin degradation by deneddylation and blocks adenomatous polyposis coli destruction via USP15
-
Huang, X., Langelotz, C., Hetfeld-Pechoc, B. K., Schwenk, W. and Dubiel, W. (2009). The COP9 signalosome mediates beta-catenin degradation by deneddylation and blocks adenomatous polyposis coli destruction via USP15. J. Mol. Biol. 391, 691-702.
-
(2009)
J. Mol. Biol.
, vol.391
, pp. 691-702
-
-
Huang, X.1
Langelotz, C.2
Hetfeld-Pechoc, B.K.3
Schwenk, W.4
Dubiel, W.5
-
55
-
-
36749010218
-
The age of crosstalk: phosphorylation, ubiquitination, and beyond
-
Hunter, T. (2007). The age of crosstalk: phosphorylation, ubiquitination, and beyond. Mol. Cell 28, 730-738.
-
(2007)
Mol. Cell
, vol.28
, pp. 730-738
-
-
Hunter, T.1
-
56
-
-
80051485763
-
Nipped in the bud: how the AMSH MIT domain helps deubiquitinate lysosome bound cargo
-
Hurley, J. H. (2011). Nipped in the bud: how the AMSH MIT domain helps deubiquitinate lysosome bound cargo. Structure 19, 1033-1035.
-
(2011)
Structure
, vol.19
, pp. 1033-1035
-
-
Hurley, J.H.1
-
58
-
-
2342658908
-
Cloning of a novel signaling molecule, AMSH-2, that potentiates transforming growth factor beta signaling
-
Ibarrola, N., Kratchmarova, I., Nakajima, D., Schiemann, W. P., Moustakas, A., Pandey, A. and Mann, M. (2004). Cloning of a novel signaling molecule, AMSH-2, that potentiates transforming growth factor beta signaling. BMC Cell Biol. 5, 2.
-
(2004)
BMC Cell Biol
, vol.5
, pp. 2
-
-
Ibarrola, N.1
Kratchmarova, I.2
Nakajima, D.3
Schiemann, W.P.4
Moustakas, A.5
Pandey, A.6
Mann, M.7
-
59
-
-
55449107515
-
Regulation of TGF-beta family signaling by E3 ubiquitin ligases
-
Inoue, Y. and Imamura, T. (2008). Regulation of TGF-beta family signaling by E3 ubiquitin ligases. Cancer Sci. 99, 2107-2112.
-
(2008)
Cancer Sci
, vol.99
, pp. 2107-2112
-
-
Inoue, Y.1
Imamura, T.2
-
60
-
-
80455143831
-
USP15 is a deubiquitylating enzyme for receptor-activated SMADs
-
Inui, M., Manfrin, A., Mamidi, A., Martello, G., Morsut, L., Soligo, S., Enzo, E., Moro, S., Polo, S., Dupont, S. et al. (2011). USP15 is a deubiquitylating enzyme for receptor-activated SMADs. Nat. Cell Biol. 13, 1368-1375.
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 1368-1375
-
-
Inui, M.1
Manfrin, A.2
Mamidi, A.3
Martello, G.4
Morsut, L.5
Soligo, S.6
Enzo, E.7
Moro, S.8
Polo, S.9
Dupont, S.10
-
61
-
-
0035422199
-
Promoting bone morphogenetic protein signaling through negative regulation of inhibitory Smads
-
Itoh, F., Asao, H., Sugamura, K., Heldin, C. H., ten Dijke, P. and Itoh, S. (2001). Promoting bone morphogenetic protein signaling through negative regulation of inhibitory Smads. EMBO J. 20, 4132-4142.
-
(2001)
EMBO J
, vol.20
, pp. 4132-4142
-
-
Itoh, F.1
Asao, H.2
Sugamura, K.3
Heldin, C.H.4
ten Dijke, P.5
Itoh, S.6
-
62
-
-
35548986309
-
Regulation of cell cycle progression and gene expression by H2A deubiquitination
-
Joo, H. Y., Zhai, L., Yang, C., Nie, S., Erdjument-Bromage, H., Tempst, P., Chang, C. and Wang, H. (2007). Regulation of cell cycle progression and gene expression by H2A deubiquitination. Nature 449, 1068-1072.
-
(2007)
Nature
, vol.449
, pp. 1068-1072
-
-
Joo, H.Y.1
Zhai, L.2
Yang, C.3
Nie, S.4
Erdjument-Bromage, H.5
Tempst, P.6
Chang, C.7
Wang, H.8
-
63
-
-
79953185042
-
Regulation of histone H2A and H2B deubiquitination and Xenopus development by USP12 and USP46
-
Joo, H. Y., Jones, A., Yang, C., Zhai, L., Smith, A. D., IV, Zhang, Z., Chandrasekharan, M. B., Sun, Z. W., Renfrow, M. B., Wang, Y. et al. (2011). Regulation of histone H2A and H2B deubiquitination and Xenopus development by USP12 and USP46. J. Biol. Chem. 286, 7190-7201.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 7190-7201
-
-
Joo, H.Y.1
Jones, A.2
Yang, C.3
Zhai, L.4
Smith IV, A.D.5
Zhang, Z.6
Chandrasekharan, M.B.7
Sun, Z.W.8
Renfrow, M.B.9
Wang, Y.10
-
64
-
-
79954575695
-
USP7/HAUSP stimulates repair of oxidative DNA lesions
-
Khoronenkova, S. V., Dianova, I. I., Parsons, J. L. and Dianov, G. L. (2011). USP7/HAUSP stimulates repair of oxidative DNA lesions. Nucleic Acids Res. 39, 2604-2609.
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 2604-2609
-
-
Khoronenkova, S.V.1
Dianova, I.I.2
Parsons, J.L.3
Dianov, G.L.4
-
65
-
-
68049084674
-
Breaking the chains: structure and function of the deubiquitinases
-
Komander, D., Clague, M. J. and Urbe, S. (2009a). Breaking the chains: structure and function of the deubiquitinases. Nat. Rev. Mol. Cell Biol. 10, 550-563.
-
(2009)
Nat. Rev. Mol. Cell Biol.
, vol.10
, pp. 550-563
-
-
Komander, D.1
Clague, M.J.2
Urbe, S.3
-
66
-
-
67349231313
-
Molecular discrimination of structurally equivalent Lys63-linked and linear polyubiquitin chains
-
Komander, D., Reyes-Turcu, F. J. D. F. L., Odenwaelder, P., Wilkinson, K. D. and Barford, D. (2009b). Molecular discrimination of structurally equivalent Lys63-linked and linear polyubiquitin chains. EMBO Rep. 10, 466-473.
-
(2009)
EMBO Rep
, vol.10
, pp. 466-473
-
-
Komander, D.1
Reyes-Turcu, F.2
Licchesi, J.D.3
Odenwaelder, P.4
Wilkinson, K.D.5
Barford, D.6
-
67
-
-
77957893483
-
A global census of fission yeast deubiquitinating enzyme localization and interaction networks reveals distinct compartmentalization profiles and overlapping functions in endocytosis and polarity
-
Kouranti, I., McLean, J. R., Feoktistova, A., Liang, P., Johnson, A. E., Roberts-Galbraith, R. H. and Gould, K. L. (2010). A global census of fission yeast deubiquitinating enzyme localization and interaction networks reveals distinct compartmentalization profiles and overlapping functions in endocytosis and polarity. PLoS Biol. 8, e1000471.
-
(2010)
PLoS Biol
, vol.8
-
-
Kouranti, I.1
McLean, J.R.2
Feoktistova, A.3
Liang, P.4
Johnson, A.E.5
Roberts-Galbraith, R.H.6
Gould, K.L.7
-
68
-
-
0041967054
-
The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination
-
Kovalenko, A., Chable-Bessia, C., Cantarella, G., Israel, A., Wallach, D. and Courtois, G. (2003). The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination. Nature 424, 801-805.
-
(2003)
Nature
, vol.424
, pp. 801-805
-
-
Kovalenko, A.1
Chable-Bessia, C.2
Cantarella, G.3
Israel, A.4
Wallach, D.5
Courtois, G.6
-
69
-
-
79251554350
-
The deubiquitinating enzyme USP-46 negatively regulates the degradation of glutamate receptors to control their abundance in the ventral nerve cord of Caenorhabditis elegans
-
Kowalski, J. R., Dahlberg, C. L. and Juo, P. (2011). The deubiquitinating enzyme USP-46 negatively regulates the degradation of glutamate receptors to control their abundance in the ventral nerve cord of Caenorhabditis elegans. J. Neurosci. 31, 1341-1354.
-
(2011)
J. Neurosci.
, vol.31
, pp. 1341-1354
-
-
Kowalski, J.R.1
Dahlberg, C.L.2
Juo, P.3
-
70
-
-
79952280797
-
The Machado-Joseph disease deubiquitylase ATX-3 couples longevity and proteostasis
-
Kuhlbrodt, K., Janiesch, P. C., Kevei, E., Segref, A., Barikbin, R. and Hoppe, T. (2011). The Machado-Joseph disease deubiquitylase ATX-3 couples longevity and proteostasis. Nat. Cell Biol. 13, 273-281.
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 273-281
-
-
Kuhlbrodt, K.1
Janiesch, P.C.2
Kevei, E.3
Segref, A.4
Barikbin, R.5
Hoppe, T.6
-
71
-
-
80052597874
-
The tightly controlled deubiquitination activity of the human SAGA complex differentially modifies distinct gene regulatory elements
-
Lang, G., Bonnet, J., Umlauf, D., Karmodiya, K., Koffler, J., Stierle, M., Devys, D. and Tora, L. (2011). The tightly controlled deubiquitination activity of the human SAGA complex differentially modifies distinct gene regulatory elements. Mol. Cell. Biol. 31, 3734-3744.
-
(2011)
Mol. Cell. Biol.
, vol.31
, pp. 3734-3744
-
-
Lang, G.1
Bonnet, J.2
Umlauf, D.3
Karmodiya, K.4
Koffler, J.5
Stierle, M.6
Devys, D.7
Tora, L.8
-
72
-
-
65649128660
-
K63-linked ubiquitin chains as a specific signal for protein sorting into the multivesicular body pathway
-
Lauwers, E., Jacob, C. and Andre, B. (2009). K63-linked ubiquitin chains as a specific signal for protein sorting into the multivesicular body pathway. J. Cell Biol. 185, 493-502.
-
(2009)
J. Cell Biol.
, vol.185
, pp. 493-502
-
-
Lauwers, E.1
Jacob, C.2
Andre, B.3
-
73
-
-
77956527159
-
Enhancement of proteasome activity by a small-molecule inhibitor of USP14
-
Lee, B. H., Lee, M. J., Park, S., Oh, D. C., Elsasser, S., Chen, P. C., Gartner, C., Dimova, N., Hanna, J., Gygi, S. P. et al. (2010a). Enhancement of proteasome activity by a small-molecule inhibitor of USP14. Nature 467, 179-184.
-
(2010)
Nature
, vol.467
, pp. 179-184
-
-
Lee, B.H.1
Lee, M.J.2
Park, S.3
Oh, D.C.4
Elsasser, S.5
Chen, P.C.6
Gartner, C.7
Dimova, N.8
Hanna, J.9
Gygi, S.P.10
-
74
-
-
77951210668
-
Human ELG1 regulates the level of ubiquitinated proliferating cell nuclear antigen (PCNA) through Its interactions with PCNA and USP1
-
Lee, K. Y., Yang, K., Cohn, M. A., Sikdar, N., D'Andrea, A. D. and Myung, K. (2010b). Human ELG1 regulates the level of ubiquitinated proliferating cell nuclear antigen (PCNA) through Its interactions with PCNA and USP1. J. Biol. Chem. 285, 10362-10369.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 10362-10369
-
-
Lee, K.Y.1
Yang, K.2
Cohn, M.A.3
Sikdar, N.4
D'Andrea, A.D.5
Myung, K.6
-
75
-
-
0037061508
-
Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization
-
Li, M., Chen, D., Shiloh, A., Luo, J., Nikolaev, A. Y., Qin, J. and Gu, W. (2002). Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization. Nature 416, 648-653.
-
(2002)
Nature
, vol.416
, pp. 648-653
-
-
Li, M.1
Chen, D.2
Shiloh, A.3
Luo, J.4
Nikolaev, A.Y.5
Qin, J.6
Gu, W.7
-
76
-
-
80053501671
-
Beclin1 controls the levels of p53 by regulating the deubiquitination qctivity of USP10 and USP13
-
Liu, J., Xia, H., Kim, M., Xu, L., Li, Y., Zhang, L., Cai, Y., Norberg, H. V., Zhang, T., Furuya, T. et al. (2011). Beclin1 controls the levels of p53 by regulating the deubiquitination qctivity of USP10 and USP13. Cell 147, 223-234.
-
(2011)
Cell
, vol.147
, pp. 223-234
-
-
Liu, J.1
Xia, H.2
Kim, M.3
Xu, L.4
Li, Y.5
Zhang, L.6
Cai, Y.7
Norberg, H.V.8
Zhang, T.9
Furuya, T.10
-
77
-
-
79956128376
-
The ubiquitin-specific protease USP34 regulates axin stability and Wnt/β-catenin signaling
-
Lui, T. T. H., Lacroix, C., Ahmed, S. M., Goldenberg, S. J., Leach, C. A., Daulat, A. M. and Angers, S. (2011). The ubiquitin-specific protease USP34 regulates axin stability and Wnt/β-catenin signaling. Mol. Cell. Biol. 31, 2053-2065.
-
(2011)
Mol. Cell. Biol.
, vol.31
, pp. 2053-2065
-
-
Lui, T.T.H.1
Lacroix, C.2
Ahmed, S.M.3
Goldenberg, S.J.4
Leach, C.A.5
Daulat, A.M.6
Angers, S.7
-
78
-
-
77955419051
-
Ubiquitin-specific proteases 7 and 11 modulate Polycomb regulation of the INK4a tumour suppressor
-
Maertens, G. N., El Messaoudi-Aubert, S., Elderkin, S., Hiom, K. and Peters, G. (2010). Ubiquitin-specific proteases 7 and 11 modulate Polycomb regulation of the INK4a tumour suppressor. EMBO J. 29, 2553-2565.
-
(2010)
EMBO J
, vol.29
, pp. 2553-2565
-
-
Maertens, G.N.1
El Messaoudi-Aubert, S.2
Elderkin, S.3
Hiom, K.4
Peters, G.5
-
79
-
-
34249947699
-
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage
-
Matsuoka, S., Ballif, B. A., Smogorzewska, A., McDonald, E. R., 3rd, Hurov, K. E., Luo, J., Bakalarski, C. E., Zhao, Z., Solimini, N., Lerenthal, Y. et al. (2007). ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. Science 316, 1160-1166.
-
(2007)
Science
, vol.316
, pp. 1160-1166
-
-
Matsuoka, S.1
Ballif, B.A.2
Smogorzewska, A.3
McDonald III, E.R.4
Hurov, K.E.5
Luo, J.6
Bakalarski, C.E.7
Zhao, Z.8
Solimini, N.9
Lerenthal, Y.10
-
80
-
-
4143080425
-
AMSH is an endosome-associated ubiquitin isopeptidase
-
McCullough, J., Clague, M. J. and Urbe, S. (2004). AMSH is an endosome-associated ubiquitin isopeptidase. J. Cell Biol. 166, 487-492.
-
(2004)
J. Cell Biol.
, vol.166
, pp. 487-492
-
-
McCullough, J.1
Clague, M.J.2
Urbe, S.3
-
81
-
-
30944464589
-
Activation of the endosome-associated ubiquitin isopeptidase AMSH by STAM, a component of the multivesicular body-sorting machinery
-
McCullough, J., Row, P. E., Lorenzo, O., Doherty, M., Beynon, R., Clague, M. J. and Urbe, S. (2006). Activation of the endosome-associated ubiquitin isopeptidase AMSH by STAM, a component of the multivesicular body-sorting machinery. Curr. Biol. 16, 160-165.
-
(2006)
Curr. Biol.
, vol.16
, pp. 160-165
-
-
McCullough, J.1
Row, P.E.2
Lorenzo, O.3
Doherty, M.4
Beynon, R.5
Clague, M.J.6
Urbe, S.7
-
82
-
-
69449086077
-
No strings attached: the ESCRT machinery in viral budding and cytokinesis
-
McDonald, B. and Martin-Serrano, J. (2009). No strings attached: the ESCRT machinery in viral budding and cytokinesis. J. Cell Sci. 122, 2167-2177.
-
(2009)
J. Cell Sci.
, vol.122
, pp. 2167-2177
-
-
McDonald, B.1
Martin-Serrano, J.2
-
83
-
-
27644438783
-
Regulation of epidermal growth factor receptor down-regulation by UBPY-mediated deubiquitination at endosomes
-
Mizuno, E., Iura, T., Mukai, A., Yoshimori, T., Kitamura, N. and Komada, M. (2005). Regulation of epidermal growth factor receptor down-regulation by UBPY-mediated deubiquitination at endosomes. Mol. Biol. Cell 16, 5163-5174.
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 5163-5174
-
-
Mizuno, E.1
Iura, T.2
Mukai, A.3
Yoshimori, T.4
Kitamura, N.5
Komada, M.6
-
84
-
-
33745754789
-
A Deubiquitinating enzyme UBPY regulates the level of protein ubiquitination on endosomes
-
Mizuno, E., Kobayashi, K., Yamamoto, A., Kitamura, N. and Komada, M. (2006). A Deubiquitinating enzyme UBPY regulates the level of protein ubiquitination on endosomes. Traffic 7, 1017-10131.
-
(2006)
Traffic
, vol.7
, pp. 1017-10131
-
-
Mizuno, E.1
Kobayashi, K.2
Yamamoto, A.3
Kitamura, N.4
Komada, M.5
-
85
-
-
34948911522
-
Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis
-
Morita, E., Sandrin, V., Chung, H. Y., Morham, S. G., Gygi, S. P., Rodesch, C. K. and Sundquist, W. I. (2007). Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis. EMBO J. 26, 4215-4227.
-
(2007)
EMBO J
, vol.26
, pp. 4215-4227
-
-
Morita, E.1
Sandrin, V.2
Chung, H.Y.3
Morham, S.G.4
Gygi, S.P.5
Rodesch, C.K.6
Sundquist, W.I.7
-
86
-
-
34547107878
-
A proteomic analysis of ataxia telangiectasia-mutated (ATM)/ATMRad3-related (ATR) substrates identifies the ubiquitin-proteasome system as a regulator for DNA damage checkpoints
-
Mu, J. J., Wang, Y., Luo, H., Leng, M., Zhang, J., Yang, T., Besusso, D., Jung, S. Y. and Qin, J. (2007). A proteomic analysis of ataxia telangiectasia-mutated (ATM)/ATMRad3-related (ATR) substrates identifies the ubiquitin-proteasome system as a regulator for DNA damage checkpoints. J. Biol. Chem. 282, 17330-17334.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 17330-17334
-
-
Mu, J.J.1
Wang, Y.2
Luo, H.3
Leng, M.4
Zhang, J.5
Yang, T.6
Besusso, D.7
Jung, S.Y.8
Qin, J.9
-
87
-
-
44449130420
-
Dynamic regulation of ubiquitylation and deubiquitylation at the central spindle during cytokinesis
-
Mukai, A., Mizuno, E., Kobayashi, K., Matsumoto, M., Nakayama, K.I., Kitamura, N. and Komada, M. (2008). Dynamic regulation of ubiquitylation and deubiquitylation at the central spindle during cytokinesis. J. Cell Sci. 121, 1325-1333.
-
(2008)
J. Cell Sci.
, vol.121
, pp. 1325-1333
-
-
Mukai, A.1
Mizuno, E.2
Kobayashi, K.3
Matsumoto, M.4
Nakayama, K.I.5
Kitamura, N.6
Komada, M.7
-
88
-
-
77954903507
-
Balanced ubiquitylation and deubiquitylation of Frizzled regulate cellular responsiveness to Wg/Wnt
-
Mukai, A., Yamamoto-Hino, M., Awano, W., Watanabe, W., Komada, M. and Goto, S. (2010). Balanced ubiquitylation and deubiquitylation of Frizzled regulate cellular responsiveness to Wg/Wnt. EMBO J. 29, 2114-2125.
-
(2010)
EMBO J
, vol.29
, pp. 2114-2125
-
-
Mukai, A.1
Yamamoto-Hino, M.2
Awano, W.3
Watanabe, W.4
Komada, M.5
Goto, S.6
-
89
-
-
79958030960
-
The USP1/UAF1 complex promotes double-strand break repair through homologous recombination
-
Murai, J., Yang, K., Dejsuphong, D., Hirota, K., Takeda, S. and D'Andrea, A. D. (2011). The USP1/UAF1 complex promotes double-strand break repair through homologous recombination. Mol. Cell. Biol. 31, 2462-2469.
-
(2011)
Mol. Cell. Biol.
, vol.31
, pp. 2462-2469
-
-
Murai, J.1
Yang, K.2
Dejsuphong, D.3
Hirota, K.4
Takeda, S.5
D'Andrea, A.D.6
-
90
-
-
77955867565
-
Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1
-
Nakada, S., Tai, I., Panier, S., Al-Hakim, A., Iemura, S., Juang, Y. C., O'Donnell, L., Kumakubo, A., Munro, M., Sicheri, F. et al. (2010). Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1. Nature 466, 941-946.
-
(2010)
Nature
, vol.466
, pp. 941-946
-
-
Nakada, S.1
Tai, I.2
Panier, S.3
Al-Hakim, A.4
Iemura, S.5
Juang, Y.C.6
O'Donnell, L.7
Kumakubo, A.8
Munro, M.9
Sicheri, F.10
-
91
-
-
38149081168
-
Deubiquitylation of histone H2A activates transcriptional initiation via trans-histone cross-talk with H3K4 di- and trimethylation
-
Nakagawa, T., Kajitani, T., Togo, S., Masuko, N., Ohdan, H., Hishikawa, Y., Koji, T., Matsuyama, T., Ikura, T., Muramatsu, M. et al. (2008). Deubiquitylation of histone H2A activates transcriptional initiation via trans-histone cross-talk with H3K4 di- and trimethylation. Genes Dev. 22, 37-49.
-
(2008)
Genes Dev
, vol.22
, pp. 37-49
-
-
Nakagawa, T.1
Kajitani, T.2
Togo, S.3
Masuko, N.4
Ohdan, H.5
Hishikawa, Y.6
Koji, T.7
Matsuyama, T.8
Ikura, T.9
Muramatsu, M.10
-
92
-
-
33646729226
-
Clathrin anchors deubiquitinating enzymes, AMSH and AMSH-like protein, on early endosomes
-
Nakamura, M., Tanaka, N., Kitamura, N. and Komada, M. (2006). Clathrin anchors deubiquitinating enzymes, AMSH and AMSH-like protein, on early endosomes. Genes Cells 11, 593-606.
-
(2006)
Genes Cells
, vol.11
, pp. 593-606
-
-
Nakamura, M.1
Tanaka, N.2
Kitamura, N.3
Komada, M.4
-
93
-
-
48249124967
-
Regulation of mitochondrial morphology by USP30, a deubiquitinating enzyme present in the mitochondrial outer membrane
-
Nakamura, N. and Hirose, S. (2008). Regulation of mitochondrial morphology by USP30, a deubiquitinating enzyme present in the mitochondrial outer membrane. Mol. Biol. Cell 19, 1903-1911.
-
(2008)
Mol. Biol. Cell
, vol.19
, pp. 1903-1911
-
-
Nakamura, N.1
Hirose, S.2
-
94
-
-
36049036216
-
Human USP3 Is a chromatin modifier required for S phase progression and genome stability
-
Nicassio, F., Corrado, N., Vissers, J. H., Areces, L. B., Bergink, S., Marteijn, J. A., Geverts, B., Houtsmuller, A. B., Vermeulen, W., Di Fiore, P. P. et al. (2007). Human USP3 Is a chromatin modifier required for S phase progression and genome stability. Curr. Biol, 17, 1972-1977.
-
(2007)
Curr. Biol
, vol.17
, pp. 1972-1977
-
-
Nicassio, F.1
Corrado, N.2
Vissers, J.H.3
Areces, L.B.4
Bergink, S.5
Marteijn, J.A.6
Geverts, B.7
Houtsmuller, A.B.8
Vermeulen, W.9
Di Fiore, P.P.10
-
95
-
-
34347346071
-
Essential role of ubiquitinspecific protease 8 for receptor tyrosine kinase stability and endocytic trafficking in vivo
-
Niendorf, S., Oksche, A., Kisser, A., Lohler, J., Prinz, M., Schorle, H., Feller, S., Lewitzky, M., Horak, I. and Knobeloch, K. P. (2007). Essential role of ubiquitinspecific protease 8 for receptor tyrosine kinase stability and endocytic trafficking in vivo. Mol. Cell. Biol. 27, 5029-5039.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 5029-5039
-
-
Niendorf, S.1
Oksche, A.2
Kisser, A.3
Lohler, J.4
Prinz, M.5
Schorle, H.6
Feller, S.7
Lewitzky, M.8
Horak, I.9
Knobeloch, K.P.10
-
96
-
-
13244291457
-
The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway
-
Nijman, S. M., Huang, T. T., Dirac, A. M., Brummelkamp, T. R., Kerkhoven, R. M., D'Andrea, A. D. and Bernards, R. (2005a). The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway. Mol. Cell 17, 331-339.
-
(2005)
Mol. Cell
, vol.17
, pp. 331-339
-
-
Nijman, S.M.1
Huang, T.T.2
Dirac, A.M.3
Brummelkamp, T.R.4
Kerkhoven, R.M.5
D'Andrea, A.D.6
Bernards, R.7
-
97
-
-
28344456279
-
A genomic and functional inventory of deubiquitinating enzymes
-
Nijman, S. M., Luna-Vargas, M. P., Velds, A., Brummelkamp, T. R., Dirac, A. M., Sixma, T. K. and Bernards, R. (2005b). A genomic and functional inventory of deubiquitinating enzymes. Cell 123, 773-786.
-
(2005)
Cell
, vol.123
, pp. 773-786
-
-
Nijman, S.M.1
Luna-Vargas, M.P.2
Velds, A.3
Brummelkamp, T.R.4
Dirac, A.M.5
Sixma, T.K.6
Bernards, R.7
-
98
-
-
0023336183
-
The yeast ubiquitin genes: a family of natural gene fusions
-
Ozkaynak, E., Finley, D., Solomon, M. J. and Varshavsky, A. (1987). The yeast ubiquitin genes: a family of natural gene fusions. EMBO J. 6, 1429-1439.
-
(1987)
EMBO J
, vol.6
, pp. 1429-1439
-
-
Ozkaynak, E.1
Finley, D.2
Solomon, M.J.3
Varshavsky, A.4
-
99
-
-
79951997444
-
USP47 is a deubiquitylating enzyme that regulates base excision repair by controlling steady-state levels of DNA polymerase beta
-
Parsons, J. L., Dianova, I. I., Khoronenkova, S. V., Edelmann, M. J., Kessler, B. M. and Dianov, G. L. (2011). USP47 is a deubiquitylating enzyme that regulates base excision repair by controlling steady-state levels of DNA polymerase beta. Mol. Cell 41, 609-615.
-
(2011)
Mol. Cell
, vol.41
, pp. 609-615
-
-
Parsons, J.L.1
Dianova, I.I.2
Khoronenkova, S.V.3
Edelmann, M.J.4
Kessler, B.M.5
Dianov, G.L.6
-
100
-
-
84855925244
-
Regulation of the activation of the Fanconi anemia pathway by the p21 cyclin-dependent kinase inhibitor
-
Rego, M. A., Harney, J. A., Mauro, M., Shen, M. and Howlett, N. G. (2011). Regulation of the activation of the Fanconi anemia pathway by the p21 cyclin-dependent kinase inhibitor. Oncogene 31, 366-375
-
(2011)
Oncogene
, vol.31
, pp. 366-375
-
-
Rego, M.A.1
Harney, J.A.2
Mauro, M.3
Shen, M.4
Howlett, N.G.5
-
101
-
-
67650620318
-
Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes
-
Reyes-Turcu, F. E., Ventii, K. H. and Wilkinson, K. D. (2009). Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes. Annu. Rev. Biochem. 78, 363-397.
-
(2009)
Annu. Rev. Biochem.
, vol.78
, pp. 363-397
-
-
Reyes-Turcu, F.E.1
Ventii, K.H.2
Wilkinson, K.D.3
-
102
-
-
33646788800
-
The ubiquitin isopeptidase UBPY regulates endosomal ubiquitin dynamics and is essential for receptor down-regulation
-
Row, P. E., Prior, I. A., McCullough, J., Clague, M. J. and Urbe, S. (2006). The ubiquitin isopeptidase UBPY regulates endosomal ubiquitin dynamics and is essential for receptor down-regulation. J. Biol. Chem. 281, 12618-12624.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 12618-12624
-
-
Row, P.E.1
Prior, I.A.2
McCullough, J.3
Clague, M.J.4
Urbe, S.5
-
103
-
-
35648973707
-
The MIT domain of UBPY constitutes a CHMP binding and endosomal localization signal required for efficient epidermal growth factor receptor degradation
-
Row, P. E., Liu, H., Hayes, S., Welchman, R., Charalabous, P., Hofmann, K., Clague, M. J., Sanderson, C. M. and Urbe, S. (2007). The MIT domain of UBPY constitutes a CHMP binding and endosomal localization signal required for efficient epidermal growth factor receptor degradation. J. Biol. Chem. 282, 30929-30937.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 30929-30937
-
-
Row, P.E.1
Liu, H.2
Hayes, S.3
Welchman, R.4
Charalabous, P.5
Hofmann, K.6
Clague, M.J.7
Sanderson, C.M.8
Urbe, S.9
-
105
-
-
52149103164
-
Structural basis for specific cleavage of Lys 63-linked polyubiquitin chains
-
Sato, Y., Yoshikawa, A., Yamagata, A., Mimura, H., Yamashita, M., Ookata, K., Nureki, O., Iwai, K., Komada, M. and Fukai, S. (2008). Structural basis for specific cleavage of Lys 63-linked polyubiquitin chains. Nature 455, 358-362.
-
(2008)
Nature
, vol.455
, pp. 358-362
-
-
Sato, Y.1
Yoshikawa, A.2
Yamagata, A.3
Mimura, H.4
Yamashita, M.5
Ookata, K.6
Nureki, O.7
Iwai, K.8
Komada, M.9
Fukai, S.10
-
106
-
-
77952429798
-
Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB
-
Scheuermann, J. C., de Ayala Alonso, A. G., Oktaba, K., Ly-Hartig, N., McGinty, R. K., Fraterman, S., Wilm, M., Muir, T. W. and Muller, J. (2010). Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB. Nature 465, 243-247.
-
(2010)
Nature
, vol.465
, pp. 243-247
-
-
Scheuermann, J.C.1
de Ayala Alonso, A.G.2
Oktaba, K.3
Ly-Hartig, N.4
McGinty, R.K.5
Fraterman, S.6
Wilm, M.7
Muir, T.W.8
Muller, J.9
-
107
-
-
36448936383
-
TGFbeta-SMAD signal transduction: molecular specificity and functional flexibility
-
Schmierer, B. and Hill, C. S. (2007). TGFbeta-SMAD signal transduction: molecular specificity and functional flexibility. Nat. Rev Mol. Cell Biol. 8, 970-982.
-
(2007)
Nat. Rev Mol. Cell Biol.
, vol.8
, pp. 970-982
-
-
Schmierer, B.1
Hill, C.S.2
-
108
-
-
62549140202
-
The Rap80-BRCC36 de-ubiquitinating enzyme complex antagonizes RNF8-Ubc13-dependent ubiquitination events at DNA double strand breaks
-
Shao, G., Lilli, D. R., Patterson-Fortin, J., Coleman, K. A., Morrissey, D. E. and Greenberg, R. A. (2009). The Rap80-BRCC36 de-ubiquitinating enzyme complex antagonizes RNF8-Ubc13-dependent ubiquitination events at DNA double strand breaks. Proc. Natl. Acad. Sci. USA 106, 3166-3671.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 3166-3671
-
-
Shao, G.1
Lilli, D.R.2
Patterson-Fortin, J.3
Coleman, K.A.4
Morrissey, D.E.5
Greenberg, R.A.6
-
109
-
-
66149116039
-
Beta-arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2
-
Shenoy, S. K., Modi, A. S., Shukla, A. K., Xiao, K., Berthouze, M., Ahn, S., Wilkinson, K. D., Miller, W. E. and Lefkowitz, R. J. (2009). Beta-arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2. Proc. Natl. Acad. Sci. USA 106, 6650-6655.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 6650-6655
-
-
Shenoy, S.K.1
Modi, A.S.2
Shukla, A.K.3
Xiao, K.4
Berthouze, M.5
Ahn, S.6
Wilkinson, K.D.7
Miller, W.E.8
Lefkowitz, R.J.9
-
110
-
-
33644763022
-
The APC tumour suppressor counteracts β-catenin activation and H3K4 methylation at Wnt target genes
-
Sierra, J., Yoshida, T., Joazeiro, C. A. and Jones, K. A. (2006). The APC tumour suppressor counteracts β-catenin activation and H3K4 methylation at Wnt target genes. Genes Dev. 20, 586-600.
-
(2006)
Genes Dev
, vol.20
, pp. 586-600
-
-
Sierra, J.1
Yoshida, T.2
Joazeiro, C.A.3
Jones, K.A.4
-
111
-
-
80051495469
-
Structural Basis for ESCRTIII CHMP3 Recruitment of AMSH
-
Solomons, J., Sabin, C., Poudevigne, E., Usami, Y., Hulsik, D. L., Macheboeuf, P., Hartlieb, B., Gottlinger, H. and Weissenhorn, W. (2011). Structural Basis for ESCRTIII CHMP3 Recruitment of AMSH. Structure 19, 1149-1159.
-
(2011)
Structure
, vol.19
, pp. 1149-1159
-
-
Solomons, J.1
Sabin, C.2
Poudevigne, E.3
Usami, Y.4
Hulsik, D.L.5
Macheboeuf, P.6
Hartlieb, B.7
Gottlinger, H.8
Weissenhorn, W.9
-
112
-
-
77954523079
-
The Prp19 complex and the Usp4Sart3 deubiquitinating enzyme control reversible ubiquitination at the spliceosome
-
Song, E. J., Werner, S. L., Neubauer, J., Stegmeier, F., Aspden, J., Rio, D., Harper, J. W., Elledge, S. J., Kirschner, M. W. and Rape, M. (2010). The Prp19 complex and the Usp4Sart3 deubiquitinating enzyme control reversible ubiquitination at the spliceosome. Genes Dev. 24, 1434-1447.
-
(2010)
Genes Dev
, vol.24
, pp. 1434-1447
-
-
Song, E.J.1
Werner, S.L.2
Neubauer, J.3
Stegmeier, F.4
Aspden, J.5
Rio, D.6
Harper, J.W.7
Elledge, S.J.8
Kirschner, M.W.9
Rape, M.10
-
113
-
-
67649634849
-
Defining the human deubiquitinating enzyme interaction landscape
-
Sowa, M. E., Bennett, E. J., Gygi, S. P. and Harper, J. W. (2009). Defining the human deubiquitinating enzyme interaction landscape. Cell 138, 389-403.
-
(2009)
Cell
, vol.138
, pp. 389-403
-
-
Sowa, M.E.1
Bennett, E.J.2
Gygi, S.P.3
Harper, J.W.4
-
114
-
-
58149311474
-
Opposing activities of the Snx3-retromer complex and ESCRT proteins mediate regulated cargo sorting at a common endosome
-
Strochlic, T. I., Schmiedekamp, B. C., Lee, J., Katzmann, D. J. and Burd, C. G. (2008). Opposing activities of the Snx3-retromer complex and ESCRT proteins mediate regulated cargo sorting at a common endosome. Mol. Biol. Cell 19, 4694-4706.
-
(2008)
Mol. Biol. Cell
, vol.19
, pp. 4694-4706
-
-
Strochlic, T.I.1
Schmiedekamp, B.C.2
Lee, J.3
Katzmann, D.J.4
Burd, C.G.5
-
115
-
-
77957005350
-
The various roles of ubiquitin in Wnt pathway regulation
-
Tauriello, D. V. and Maurice, M. M. (2010). The various roles of ubiquitin in Wnt pathway regulation. Cell Cycle 9, 3700-3709.
-
(2010)
Cell Cycle
, vol.9
, pp. 3700-3709
-
-
Tauriello, D.V.1
Maurice, M.M.2
-
116
-
-
77649259009
-
Loss of the tumor suppressor CYLD enhances Wnt/beta-catenin signaling through K63-linked ubiquitination of Dvl
-
Tauriello, D. V., Haegebarth, A., Kuper, I., Edelmann, M. J., Henraat, M., Canningavan Dijk, M. R., Kessler, B. M., Clevers, H. and Maurice, M. M. (2010). Loss of the tumor suppressor CYLD enhances Wnt/beta-catenin signaling through K63-linked ubiquitination of Dvl. Mol. Cell 37, 607-619.
-
(2010)
Mol. Cell
, vol.37
, pp. 607-619
-
-
Tauriello, D.V.1
Haegebarth, A.2
Kuper, I.3
Edelmann, M.J.4
Henraat, M.5
Canningavan Dijk, M.R.6
Kessler, B.M.7
Clevers, H.8
Maurice, M.M.9
-
117
-
-
27444445613
-
c-Cbl and Cbl-b ubiquitin ligases: substrate diversity and the negative regulation of signalling responses
-
Thien, C. B. and Langdon, W. Y. (2005). c-Cbl and Cbl-b ubiquitin ligases: substrate diversity and the negative regulation of signalling responses. Biochem. J. 391, 153-166.
-
(2005)
Biochem. J.
, vol.391
, pp. 153-166
-
-
Thien, C.B.1
Langdon, W.Y.2
-
118
-
-
80053598334
-
isoformspecific localization of the deubiquitinase USP33 to the Golgi apparatus
-
Thorne, C., Eccles, R. L., Coulson, J. M., Urbe, S. and Clague, M. J. (2011). isoformspecific localization of the deubiquitinase USP33 to the Golgi apparatus. Traffic 12, 1563-1574.
-
(2011)
Traffic
, vol.12
, pp. 1563-1574
-
-
Thorne, C.1
Eccles, R.L.2
Coulson, J.M.3
Urbe, S.4
Clague, M.J.5
-
119
-
-
39449084931
-
Trabid, a new positive regulator of Wnt-induced transcription with preference for binding and cleaving K63-linked ubiquitin chains
-
Tran, H., Hamada, F., Schwarz-Romond, T. and Bienz, M. (2008). Trabid, a new positive regulator of Wnt-induced transcription with preference for binding and cleaving K63-linked ubiquitin chains. Genes Dev. 22, 528-542.
-
(2008)
Genes Dev
, vol.22
, pp. 528-542
-
-
Tran, H.1
Hamada, F.2
Schwarz-Romond, T.3
Bienz, M.4
-
120
-
-
0042467558
-
CYLD is a deubiquitinating enzyme that negatively regulates NFkappaB activation by TNFR family members
-
Trompouki, E., Hatzivassiliou, E., Tsichritzis, T., Farmer, H., Ashworth, A. and Mosialos, G. (2003). CYLD is a deubiquitinating enzyme that negatively regulates NFkappaB activation by TNFR family members. Nature 424, 793-796.
-
(2003)
Nature
, vol.424
, pp. 793-796
-
-
Trompouki, E.1
Hatzivassiliou, E.2
Tsichritzis, T.3
Farmer, H.4
Ashworth, A.5
Mosialos, G.6
-
121
-
-
74549158762
-
Genome-wide loss-of-function analysis of deubiquitylating enzymes for zebrafish development
-
Tse, W. K. F., Eisenhaber, B., Ho, S. H. K., Ng, Q., Eisenhaber, F. and Jiang, Y.-J. (2009). Genome-wide loss-of-function analysis of deubiquitylating enzymes for zebrafish development. BMC Genomics 10, 637.
-
(2009)
BMC Genomics
, vol.10
, pp. 637
-
-
Tse, W.K.F.1
Eisenhaber, B.2
Ho, S.H.K.3
Ng, Q.4
Eisenhaber, F.5
Jiang, Y.-J.6
-
122
-
-
77953915005
-
Ubiquitin signalling in DNA replication and repair
-
Ulrich, H. D. and Walden, H. (2010). Ubiquitin signalling in DNA replication and repair. Nat. Rev. Mol. Cell Biol. 11, 479-489.
-
(2010)
Nat. Rev. Mol. Cell Biol.
, vol.11
, pp. 479-489
-
-
Ulrich, H.D.1
Walden, H.2
-
123
-
-
33749188883
-
FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP
-
van der Horst, A., de Vries-Smits, A. M., Brenkman, A. B., van Triest, M. H., van den Broek, N., Colland, F., Maurice, M. M. and Burgering, B. M. (2006). FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP. Nat. Cell Biol. 8, 1064-1073.
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 1064-1073
-
-
van der Horst, A.1
de Vries-Smit, A.M.2
Brenkman, A.B.3
van Triest, M.H.4
van den Broek, N.5
Colland, F.6
Maurice, M.M.7
Burgering, B.M.8
-
124
-
-
14644406268
-
GMP synthetase stimulates histone H2B deubiquitylation by the epigenetic silencer USP7
-
van der Knaap, J. A., Kumar, B. R., Moshkin, Y. M., Langenberg, K., Krijgsveld, J., Heck, A. J., Karch, F. and Verrijzer, C. P. (2005). GMP synthetase stimulates histone H2B deubiquitylation by the epigenetic silencer USP7. Mol. Cell 17, 695-707.
-
(2005)
Mol. Cell
, vol.17
, pp. 695-707
-
-
van der Knaap, J.A.1
Kumar, B.R.2
Moshkin, Y.M.3
Langenberg, K.4
Krijgsveld, J.5
Heck, A.J.6
Karch, F.7
Verrijzer, C.P.8
-
125
-
-
77956903406
-
-
Virdee, S., Ye, Y., Nguyen, D. P., Komander, D. and Chin, J. W. (2010). Engineered diubiquitin synthesis reveals Lys-29-isopeptide specificity of an OTU deubiquitinase. Nat. Chem. Biol. 6, 750-756.
-
(2010)
Nat. Chem. Biol.
, vol.6
, pp. 750-756
-
-
Virdee, S.1
Ye, Y.2
Nguyen, D.P.3
Komander, D.4
Chin, J.W.5
-
126
-
-
36749025467
-
Ubc13/RNF8 ubiquitin ligases control foci formation of the Rap80/Abraxas/Brca1/Brcc36 complex in response to DNA damage
-
Wang, B. and Elledge, S. J. (2007). Ubc13/RNF8 ubiquitin ligases control foci formation of the Rap80/Abraxas/Brca1/Brcc36 complex in response to DNA damage. Proc. Natl. Acad. Sci. USA 104, 20759-20763.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 20759-20763
-
-
Wang, B.1
Elledge, S.J.2
-
127
-
-
33748988214
-
Regulation of retrotranslocation by p97-associated deubiquitinating enzyme ataxin-3
-
Wang, Q., Li, L. and Ye, Y. (2006). Regulation of retrotranslocation by p97-associated deubiquitinating enzyme ataxin-3. J. Cell Biol. 174, 963-971.
-
(2006)
J. Cell Biol.
, vol.174
, pp. 963-971
-
-
Wang, Q.1
Li, L.2
Ye, Y.3
-
128
-
-
1842509180
-
VCIP135 acts as a deubiquitinating enzyme during p97-p47-mediated reassembly of mitotic Golgi fragments
-
Wang, Y., Satoh, A., Warren, G. and Meyer, H. H. (2004). VCIP135 acts as a deubiquitinating enzyme during p97-p47-mediated reassembly of mitotic Golgi fragments. J. Cell Biol. 164, 973-978.
-
(2004)
J. Cell Biol.
, vol.164
, pp. 973-978
-
-
Wang, Y.1
Satoh, A.2
Warren, G.3
Meyer, H.H.4
-
129
-
-
27944498719
-
The deubiquitinating enzyme UCH37 interacts with Smads and regulates TGF-beta signalling
-
Wicks, S. J., Haros, K., Maillard, M., Song, L., Cohen, R. E., Dijke, P. T. and Chantry, A. (2005). The deubiquitinating enzyme UCH37 interacts with Smads and regulates TGF-beta signalling. Oncogene 24, 8080-8084.
-
(2005)
Oncogene
, vol.24
, pp. 8080-8084
-
-
Wicks, S.J.1
Haros, K.2
Maillard, M.3
Song, L.4
Cohen, R.E.5
Dijke, P.T.6
Chantry, A.7
-
130
-
-
34247342216
-
The emerging shape of the ESCRT machinery
-
Williams, R. L. and Urbe, S. (2007). The emerging shape of the ESCRT machinery. Nat. Rev. Mol. Cell Biol. 8, 355-368.
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 355-368
-
-
Williams, R.L.1
Urbe, S.2
-
131
-
-
69449101044
-
The ESCRT machinery at a glance
-
Wollert, T., Yang, D., Ren, X., Lee, H. H., Im, Y. J. and Hurley, J. H. (2009). The ESCRT machinery at a glance. J. Cell Sci. 122, 2163-2166.
-
(2009)
J. Cell Sci.
, vol.122
, pp. 2163-2166
-
-
Wollert, T.1
Yang, D.2
Ren, X.3
Lee, H.H.4
Im, Y.J.5
Hurley, J.H.6
-
132
-
-
69949093459
-
Direct activation of protein kinases by unanchored polyubiquitin chains
-
Xia, Z. P., Sun, L., Chen, X., Pineda, G., Jiang, X., Adhikari, A., Zeng, W. and Chen, Z. J. (2009). Direct activation of protein kinases by unanchored polyubiquitin chains. Nature 461, 114-119.
-
(2009)
Nature
, vol.461
, pp. 114-119
-
-
Xia, Z.P.1
Sun, L.2
Chen, X.3
Pineda, G.4
Jiang, X.5
Adhikari, A.6
Zeng, W.7
Chen, Z.J.8
-
133
-
-
63049125531
-
Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation
-
Xu, P., Duong, D. M., Seyfried, N. T., Cheng, D., Xie, Y., Robert, J., Rush, J., Hochstrasser, M., Finley, D. and Peng, J. (2009). Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation. Cell 137, 133-145.
-
(2009)
Cell
, vol.137
, pp. 133-145
-
-
Xu, P.1
Duong, D.M.2
Seyfried, N.T.3
Cheng, D.4
Xie, Y.5
Robert, J.6
Rush, J.7
Hochstrasser, M.8
Finley, D.9
Peng, J.10
-
134
-
-
33746766974
-
A role for the deubiquitinating enzyme USP28 in control of the DNA-damage response
-
Zhang, D., Zaugg, K., Mak, T. W. and Elledge, S. J. (2006). A role for the deubiquitinating enzyme USP28 in control of the DNA-damage response. Cell 126, 529-542.
-
(2006)
Cell
, vol.126
, pp. 529-542
-
-
Zhang, D.1
Zaugg, K.2
Mak, T.W.3
Elledge, S.J.4
-
135
-
-
45849133054
-
USP22, an hSAGA subunit and potential cancer stem cell marker, reverses the polycomb-catalyzed ubiquitylation of histone H2A
-
Zhang, X. Y., Pfeiffer, H. K., Thorne, A. W. and McMahon, S. B. (2008a). USP22, an hSAGA subunit and potential cancer stem cell marker, reverses the polycomb-catalyzed ubiquitylation of histone H2A. Cell Cycle 7, 1522-1524.
-
(2008)
Cell Cycle
, vol.7
, pp. 1522-1524
-
-
Zhang, X.Y.1
Pfeiffer, H.K.2
Thorne, A.W.3
McMahon, S.B.4
-
136
-
-
38149078715
-
The putative cancer stem cell marker USP22 is a subunit of the human SAGA complex required for activated transcription and cell-cycle progression
-
Zhang, X. Y., Varthi, M., Sykes, S. M., Phillips, C., Warzecha, C., Zhu, W., Wyce, A., Thorne, A. W., Berger, S. L. and McMahon, S. B. (2008b). The putative cancer stem cell marker USP22 is a subunit of the human SAGA complex required for activated transcription and cell-cycle progression. Mol. Cell 29, 102-111.
-
(2008)
Mol. Cell
, vol.29
, pp. 102-111
-
-
Zhang, X.Y.1
Varthi, M.2
Sykes, S.M.3
Phillips, C.4
Warzecha, C.5
Zhu, W.6
Wyce, A.7
Thorne, A.W.8
Berger, S.L.9
McMahon, S.B.10
-
137
-
-
72949089936
-
The ubiquitin specific protease 4 (Usp4) is a new player in the Wnt signalling pathway
-
Zhao, B., Schlesiger, C., Masucci, M. G. and Lindsten, K. (2009). The ubiquitin specific protease 4 (Usp4) is a new player in the Wnt signalling pathway. J. Cell Mol. Med. 13, 1886-1895.
-
(2009)
J. Cell Mol. Med.
, vol.13
, pp. 1886-1895
-
-
Zhao, B.1
Schlesiger, C.2
Masucci, M.G.3
Lindsten, K.4
-
138
-
-
38149068875
-
A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing
-
Zhao, Y., Lang, G., Ito, S., Bonnet, J., Metzger, E., Sawatsubashi, S., Suzuki, E., Le Guezennec, X., Stunnenberg, H. G., Krasnov, A. et al. (2008). A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing. Mol. Cell 29, 92-101.
-
(2008)
Mol. Cell
, vol.29
, pp. 92-101
-
-
Zhao, Y.1
Lang, G.2
Ito, S.3
Bonnet, J.4
Metzger, E.5
Sawatsubashi, S.6
Suzuki, E.7
Le Guezennec, X.8
Stunnenberg, H.G.9
Krasnov, A.10
-
139
-
-
34547730282
-
A histone H2A deubiquitinase complex coordinating histone acetylation and H1 dissociation in transcriptional regulation
-
Zhu, P., Zhou, W., Wang, J., Puc, J., Ohgi, K. A., Erdjument-Bromage, H., Tempst, P., Glass, C. K. and Rosenfeld, M. G. (2007). A histone H2A deubiquitinase complex coordinating histone acetylation and H1 dissociation in transcriptional regulation. Mol. Cell 27, 609-621.
-
(2007)
Mol. Cell
, vol.27
, pp. 609-621
-
-
Zhu, P.1
Zhou, W.2
Wang, J.3
Puc, J.4
Ohgi, K.A.5
Erdjument-Bromage, H.6
Tempst, P.7
Glass, C.K.8
Rosenfeld, M.G.9
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