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Volumn 20, Issue 11, 2011, Pages 2171-2181

USP1 deubiquitinase maintains phosphorylated CHK1 by limiting its DDB1-dependent degradation

Author keywords

[No Author keywords available]

Indexed keywords

CHECKPOINT KINASE 1; CYCLINE; DAMAGE SPECIFIC DNA BINDING PROTEIN 1; DNA BINDING PROTEIN; FANCONI ANEMIA GROUP D2 PROTEIN; PEPTIDASE; UNCLASSIFIED DRUG; USP1 DEUBIQUITINASE;

EID: 79956027089     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddr103     Document Type: Article
Times cited : (50)

References (61)
  • 1
    • 36749022214 scopus 로고    scopus 로고
    • The DNA damage response: ten years after
    • Harper, J.W. and Elledge, S.J. (2007) The DNA damage response: ten years after. Mol. Cell, 28, 739-745.
    • (2007) Mol. Cell , vol.28 , pp. 739-745
    • Harper, J.W.1    Elledge, S.J.2
  • 2
    • 78649336706 scopus 로고    scopus 로고
    • The DNA damage response: making it safe to play with knives
    • Ciccia, A. and Elledge, S.J. (2010) The DNA damage response: making it safe to play with knives. Mol. Cell, 40, 179-204.
    • (2010) Mol. Cell , vol.40 , pp. 179-204
    • Ciccia, A.1    Elledge, S.J.2
  • 3
    • 47749141560 scopus 로고    scopus 로고
    • ATR: an essential regulator of genome integrity
    • Cimprich, K.A. and Cortez, D. (2008) ATR: an essential regulator of genome integrity. Nat. Rev. Mol. Cell Biol., 9, 616-627.
    • (2008) Nat. Rev. Mol. Cell Biol. , vol.9 , pp. 616-627
    • Cimprich, K.A.1    Cortez, D.2
  • 4
  • 5
    • 39749178467 scopus 로고    scopus 로고
    • Loss of CHK1 function impedes DNA damage-induced FANCD2 monoubiquitination but normalizes the abnormal G2 arrest in Fanconi anemia
    • Guervilly, J.H., Mace-Aime, G. and Rosselli, F. (2008) Loss of CHK1 function impedes DNA damage-induced FANCD2 monoubiquitination but normalizes the abnormal G2 arrest in Fanconi anemia. Hum. Mol. Genet., 17, 679-689.
    • (2008) Hum. Mol. Genet. , vol.17 , pp. 679-689
    • Guervilly, J.H.1    Mace-Aime, G.2    Rosselli, F.3
  • 6
    • 34047190253 scopus 로고    scopus 로고
    • Chk1-mediated phosphorylation of FANCE is required for the Fanconi anemia/BRCA pathway
    • Wang, X., Kennedy, R.D., Ray, K., Stuckert, P., Ellenberger, T. and D'Andrea, A.D. (2007) Chk1-mediated phosphorylation of FANCE is required for the Fanconi anemia/BRCA pathway. Mol. Cell Biol., 27, 3098-3108.
    • (2007) Mol. Cell Biol. , vol.27 , pp. 3098-3108
    • Wang, X.1    Kennedy, R.D.2    Ray, K.3    Stuckert, P.4    Ellenberger, T.5    D'Andrea, A.D.6
  • 7
    • 43249094413 scopus 로고    scopus 로고
    • Chk1 and Claspin potentiate PCNA ubiquitination
    • Yang, X.H., Shiotani, B., Classon, M. and Zou, L. (2008) Chk1 and Claspin potentiate PCNA ubiquitination. Genes Dev., 22, 1147-1152.
    • (2008) Genes Dev. , vol.22 , pp. 1147-1152
    • Yang, X.H.1    Shiotani, B.2    Classon, M.3    Zou, L.4
  • 9
    • 1842614272 scopus 로고    scopus 로고
    • Recovery from DNA damage checkpoint arrest by PP1-mediated inhibition of Chk
    • den Elzen, N.R. and O'Connell, M.J. (2004) Recovery from DNA damage checkpoint arrest by PP1-mediated inhibition of Chk EMBO J., 23, 908-918.
    • (2004) EMBO J. , vol.23 , pp. 908-918
    • den Elzen, N.R.1    O'Connell, M.J.2
  • 10
    • 65549090186 scopus 로고    scopus 로고
    • DDB1 targets Chk1 to the Cul4 E3 ligase complex in normal cycling cells and in cells experiencing replication stress
    • Leung-Pineda, V., Huh, J. and Piwnica-Worms, H. (2009) DDB1 targets Chk1 to the Cul4 E3 ligase complex in normal cycling cells and in cells experiencing replication stress. Cancer Res., 69, 2630-2637.
    • (2009) Cancer Res. , vol.69 , pp. 2630-2637
    • Leung-Pineda, V.1    Huh, J.2    Piwnica-Worms, H.3
  • 12
    • 59849116083 scopus 로고    scopus 로고
    • USP7 counteracts SCFbetaTrCP- but not APCCdh1-mediated proteolysis of Claspin
    • Faustrup, H., Bekker-Jensen, S., Bartek, J., Lukas, J. and Mailand, N. (2009) USP7 counteracts SCFbetaTrCP- but not APCCdh1-mediated proteolysis of Claspin. J. Cell Biol., 184, 13-19.
    • (2009) J. Cell Biol. , vol.184 , pp. 13-19
    • Faustrup, H.1    Bekker-Jensen, S.2    Bartek, J.3    Lukas, J.4    Mailand, N.5
  • 14
    • 72249108356 scopus 로고    scopus 로고
    • Constitutive activation of the DNA damage signaling pathway in acute myeloid leukemia with complex karyotype: potential importance for checkpoint targeting therapy
    • Cavelier, C., Didier, C., Prade, N., Mansat-De Mas, V., Manenti, S., Recher, C., Demur, C. and Ducommun, B. (2009) Constitutive activation of the DNA damage signaling pathway in acute myeloid leukemia with complex karyotype: potential importance for checkpoint targeting therapy. Cancer Res., 69, 8652-8661.
    • (2009) Cancer Res. , vol.69 , pp. 8652-8661
    • Cavelier, C.1    Didier, C.2    Prade, N.3    Mansat-De Mas, V.4    Manenti, S.5    Recher, C.6    Demur, C.7    Ducommun, B.8
  • 15
  • 16
    • 0035947651 scopus 로고    scopus 로고
    • The radioresistance to killing of A1-5 cells derives from activation of the Chk1 pathway
    • Hu, B., Zhou, X.Y., Wang, X., Zeng, Z.C., Iliakis, G. and Wang, Y. (2001) The radioresistance to killing of A1-5 cells derives from activation of the Chk1 pathway. J. Biol. Chem., 276, 17693-17698.
    • (2001) J. Biol. Chem. , vol.276 , pp. 17693-17698
    • Hu, B.1    Zhou, X.Y.2    Wang, X.3    Zeng, Z.C.4    Iliakis, G.5    Wang, Y.6
  • 17
    • 33750315873 scopus 로고    scopus 로고
    • Guido Fanconi (1892-1979): a jack of all trades
    • Lobitz, S. and Velleuer, E. (2006) Guido Fanconi (1892-1979): a jack of all trades. Nat. Rev. Cancer, 6, 893-898.
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 893-898
    • Lobitz, S.1    Velleuer, E.2
  • 18
    • 68349095151 scopus 로고    scopus 로고
    • Human DNA damage response and repair deficiency syndromes: linking genomic instability and cell cycle checkpoint proficiency
    • Kerzendorfer, C. and O'Driscoll, M. (2009) Human DNA damage response and repair deficiency syndromes: linking genomic instability and cell cycle checkpoint proficiency. DNA Repair (Amst.), 8, 1139-1152.
    • (2009) DNA Repair (Amst.) , vol.8 , pp. 1139-1152
    • Kerzendorfer, C.1    O'Driscoll, M.2
  • 19
    • 34548759123 scopus 로고    scopus 로고
    • Emergence of a DNA-damage response network consisting of Fanconi anaemia and BRCA proteins
    • Wang, W. (2007) Emergence of a DNA-damage response network consisting of Fanconi anaemia and BRCA proteins. Nat. Rev. Genet., 8, 735-748.
    • (2007) Nat. Rev. Genet. , vol.8 , pp. 735-748
    • Wang, W.1
  • 21
    • 77955889790 scopus 로고    scopus 로고
    • Expanded roles of the Fanconi anemia pathway in preserving genomic stability
    • Kee, Y. and D'Andrea, A.D. (2010) Expanded roles of the Fanconi anemia pathway in preserving genomic stability. Genes Dev., 24, 1680-1694.
    • (2010) Genes Dev. , vol.24 , pp. 1680-1694
    • Kee, Y.1    D'Andrea, A.D.2
  • 23
    • 77951723100 scopus 로고    scopus 로고
    • Fanconi anemia and breast cancer susceptibility meet again
    • Levy-Lahad, E. (2010) Fanconi anemia and breast cancer susceptibility meet again. Nat. Genet., 42, 368-369.
    • (2010) Nat. Genet. , vol.42 , pp. 368-369
    • Levy-Lahad, E.1
  • 24
    • 77955498184 scopus 로고    scopus 로고
    • DNA repair has a new FAN1 club
    • O'Donnell, L. and Durocher, D. (2010) DNA repair has a new FAN1 club. Mol. Cell, 39, 167-169.
    • (2010) Mol. Cell , vol.39 , pp. 167-169
    • O'Donnell, L.1    Durocher, D.2
  • 29
    • 70349278437 scopus 로고    scopus 로고
    • The FANC pathway and mitosis: a replication legacy
    • Naim, V. and Rosselli, F. (2009) The FANC pathway and mitosis: a replication legacy. Cell Cycle, 8, 2907-2911.
    • (2009) Cell Cycle , vol.8 , pp. 2907-2911
    • Naim, V.1    Rosselli, F.2
  • 30
    • 0036796260 scopus 로고    scopus 로고
    • DNA cross-link-dependent RAD50/MRE11/NBS1 subnuclear assembly requires the Fanconi anemia C protein
    • Pichierri, P., Averbeck, D. and Rosselli, F. (2002) DNA cross-link-dependent RAD50/MRE11/NBS1 subnuclear assembly requires the Fanconi anemia C protein. Hum. Mol. Genet., 11, 2531-2546.
    • (2002) Hum. Mol. Genet. , vol.11 , pp. 2531-2546
    • Pichierri, P.1    Averbeck, D.2    Rosselli, F.3
  • 31
    • 13244298119 scopus 로고    scopus 로고
    • Fanconi anemia proteins and the s phase checkpoint
    • Pichierri, P. and Rosselli, F. (2004) Fanconi anemia proteins and the s phase checkpoint. Cell Cycle, 3, 698-700.
    • (2004) Cell Cycle , vol.3 , pp. 698-700
    • Pichierri, P.1    Rosselli, F.2
  • 34
    • 67349187702 scopus 로고    scopus 로고
    • The FANC pathway and BLM collaborate during mitosis to prevent micro-nucleation and chromosome abnormalities
    • Naim, V. and Rosselli, F. (2009) The FANC pathway and BLM collaborate during mitosis to prevent micro-nucleation and chromosome abnormalities. Nat. Cell Biol., 11, 761-768.
    • (2009) Nat. Cell Biol. , vol.11 , pp. 761-768
    • Naim, V.1    Rosselli, F.2
  • 36
    • 4143141093 scopus 로고    scopus 로고
    • BLM and the FANC proteins collaborate in a common pathway in response to stalled replication forks
    • Pichierri, P., Franchitto, A. and Rosselli, F. (2004) BLM and the FANC proteins collaborate in a common pathway in response to stalled replication forks. EMBO J., 23, 3154-3163.
    • (2004) EMBO J. , vol.23 , pp. 3154-3163
    • Pichierri, P.1    Franchitto, A.2    Rosselli, F.3
  • 37
    • 4043133287 scopus 로고    scopus 로고
    • ATR couples FANCD2 monoubiquitination to the DNA-damage response
    • Andreassen, P.R., D'Andrea, A.D. and Taniguchi, T. (2004) ATR couples FANCD2 monoubiquitination to the DNA-damage response. Genes Dev., 18, 1958-1963.
    • (2004) Genes Dev. , vol.18 , pp. 1958-1963
    • Andreassen, P.R.1    D'Andrea, A.D.2    Taniguchi, T.3
  • 40
    • 0020067168 scopus 로고
    • Flow cytometric characterization of the response of Fanconi's anemia cells to mitomycin C treatment
    • Kaiser, T.N., Lojewski, A., Dougherty, C., Juergens, L., Sahar, E. and Latt, S.A. (1982) Flow cytometric characterization of the response of Fanconi's anemia cells to mitomycin C treatment. Cytometry, 2, 291-297.
    • (1982) Cytometry , vol.2 , pp. 291-297
    • Kaiser, T.N.1    Lojewski, A.2    Dougherty, C.3    Juergens, L.4    Sahar, E.5    Latt, S.A.6
  • 46
    • 59649114341 scopus 로고    scopus 로고
    • Inactivation of murine Usp1 results in genomic instability and a Fanconi anemia phenotype
    • Kim, J.M., Parmar, K., Huang, M., Weinstock, D.M., Ruit, C.A., Kutok, J.L. and D'Andrea, A.D. (2009) Inactivation of murine Usp1 results in genomic instability and a Fanconi anemia phenotype. Dev. Cell, 16, 314-320.
    • (2009) Dev. Cell , vol.16 , pp. 314-320
    • Kim, J.M.1    Parmar, K.2    Huang, M.3    Weinstock, D.M.4    Ruit, C.A.5    Kutok, J.L.6    D'Andrea, A.D.7
  • 50
    • 33746948393 scopus 로고    scopus 로고
    • Claspin operates downstream of TopBP1 to direct ATR signaling towards Chk1 activation
    • Liu, S., Bekker-Jensen, S., Mailand, N., Lukas, C., Bartek, J. and Lukas, J. (2006) Claspin operates downstream of TopBP1 to direct ATR signaling towards Chk1 activation. Mol. Cell Biol., 26, 6056-6064.
    • (2006) Mol. Cell Biol. , vol.26 , pp. 6056-6064
    • Liu, S.1    Bekker-Jensen, S.2    Mailand, N.3    Lukas, C.4    Bartek, J.5    Lukas, J.6
  • 51
    • 24044476837 scopus 로고    scopus 로고
    • Genotoxic stress targets human Chk1 for degradation by the ubiquitin-proteasome pathway
    • Zhang, Y.W., Otterness, D.M., Chiang, G.G., Xie, W., Liu, Y.C., Mercurio, F. and Abraham, R.T. (2005) Genotoxic stress targets human Chk1 for degradation by the ubiquitin-proteasome pathway. Mol. Cell, 19, 607-618.
    • (2005) Mol. Cell , vol.19 , pp. 607-618
    • Zhang, Y.W.1    Otterness, D.M.2    Chiang, G.G.3    Xie, W.4    Liu, Y.C.5    Mercurio, F.6    Abraham, R.T.7
  • 52
    • 34547628200 scopus 로고    scopus 로고
    • Proteasome function is required for DNA damage response and fanconi anemia pathway activation
    • Jacquemont, C. and Taniguchi, T. (2007) Proteasome function is required for DNA damage response and fanconi anemia pathway activation. Cancer Res., 67, 7395-7405.
    • (2007) Cancer Res. , vol.67 , pp. 7395-7405
    • Jacquemont, C.1    Taniguchi, T.2
  • 53
    • 5444274523 scopus 로고    scopus 로고
    • Targeted ubiquitination of CDT1 by the DDB1-CUL4A-ROC1 ligase in response to DNA damage
    • Hu, J., McCall, C.M., Ohta, T. and Xiong, Y. (2004) Targeted ubiquitination of CDT1 by the DDB1-CUL4A-ROC1 ligase in response to DNA damage. Nat. Cell Biol., 6, 1003-1009.
    • (2004) Nat. Cell Biol. , vol.6 , pp. 1003-1009
    • Hu, J.1    McCall, C.M.2    Ohta, T.3    Xiong, Y.4
  • 54
    • 34250318465 scopus 로고    scopus 로고
    • DCAFs, the missing link of the CUL4-DDB1 ubiquitin ligase
    • Lee, J. and Zhou, P. (2007) DCAFs, the missing link of the CUL4-DDB1 ubiquitin ligase. Mol. Cell, 26, 775-780.
    • (2007) Mol. Cell , vol.26 , pp. 775-780
    • Lee, J.1    Zhou, P.2
  • 55
    • 70350365400 scopus 로고    scopus 로고
    • Functional interaction between the Fanconi Anemia D2 protein and proliferating cell nuclear antigen (PCNA) via a conserved putative PCNA interaction motif
    • Howlett, N.G., Harney, J.A., Rego, M.A., Kolling, F.W.T. and Glover, T.W. (2009) Functional interaction between the Fanconi Anemia D2 protein and proliferating cell nuclear antigen (PCNA) via a conserved putative PCNA interaction motif. J. Biol. Chem., 284, 28935-28942.
    • (2009) J. Biol. Chem. , vol.284 , pp. 28935-28942
    • Howlett, N.G.1    Harney, J.A.2    Rego, M.A.3    Kolling, F.W.T.4    Glover, T.W.5
  • 56
    • 77957799898 scopus 로고    scopus 로고
    • Rad18-mediated translesion synthesis of bulky DNA adducts is coupled to activation of the Fanconi anemia DNA repair pathway
    • Song, I.Y., Palle, K., Gurkar, A., Tateishi, S., Kupfer, G.M. and Vaziri, C. (2010) Rad18-mediated translesion synthesis of bulky DNA adducts is coupled to activation of the Fanconi anemia DNA repair pathway. J. Biol. Chem., 285, 31525-31536.
    • (2010) J. Biol. Chem. , vol.285 , pp. 31525-31536
    • Song, I.Y.1    Palle, K.2    Gurkar, A.3    Tateishi, S.4    Kupfer, G.M.5    Vaziri, C.6
  • 59
    • 67650569540 scopus 로고    scopus 로고
    • Impaired FANCD2 monoubiquitination and hypersensitivity to camptothecin uniquely characterize Fanconi anemia complementation group M
    • Singh, T.R., Bakker, S.T., Agarwal, S., Jansen, M., Grassman, E., Godthelp, B.C., Ali, A.M., Du, C.H., Rooimans, M.A., Fan, Q. et al. (2009) Impaired FANCD2 monoubiquitination and hypersensitivity to camptothecin uniquely characterize Fanconi anemia complementation group M. Blood, 114, 174-180.
    • (2009) Blood , vol.114 , pp. 174-180
    • Singh, T.R.1    Bakker, S.T.2    Agarwal, S.3    Jansen, M.4    Grassman, E.5    Godthelp, B.C.6    Ali, A.M.7    Du, C.H.8    Rooimans, M.A.9    Fan, Q.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.