Deubiquitinase Activities Required for Hepatocyte Growth Factor-Induced Scattering of Epithelial Cells

Current Biology

Volumn 19, Issue 17, 2009, Pages 1463-1466

  Buus, Richard ^a   Faronato, Monica ^a   Hammond, Dean E ^a   Urbé, Sylvie ^a   Clague, Michael J ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

CELLBIO

Indexed keywords

GROWTH FACTOR RECEPTOR; MET PROTEIN, HUMAN; ONCOPROTEIN; SCATTER FACTOR;

ARTICLE; CELL ADHESION; CELL MOTION; DRUG EFFECT; ENZYME ACTIVATION; HUMAN; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TUMOR CELL LINE; UBIQUITINATION;

CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; ENZYME ACTIVATION; HEPATOCYTE GROWTH FACTOR; HUMANS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS; RECEPTORS, GROWTH FACTOR; RNA INTERFERENCE; SIGNAL TRANSDUCTION; UBIQUITINATION;

EID: 69949173205     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cub.2009.07.040     Document Type: Article

References (25)

1. Birchmeier C., Birchmeier W., Gherardi E., and Vande Woude G.F. Met, metastasis, motility and more. Nat. Rev. Mol. Cell Biol. 4 (2003) 915-925
2. Gentile A., Trusolino L., and Comoglio P.M. The Met tyrosine kinase receptor in development and cancer. Cancer Metastasis Rev. 27 (2008) 85-94
3. Hunter T. The age of crosstalk: Phosphorylation, ubiquitination, and beyond. Mol. Cell 28 (2007) 730-738
4. Welchman R.L., Gordon C., and Mayer R.J. Ubiquitin and ubiquitin-like proteins as multifunctional signals. Nat. Rev. Mol. Cell Biol. 6 (2005) 599-609
5. Scheel, H. (2005). Comparative analysis of the ubiquitin-proteasome system in Homo sapiens and Saccharomyces cerevisiae. PhD thesis, University of Cologne, Cologne, Germany.
6. Nijman S.M., Luna-Vargas M.P., Velds A., Brummelkamp T.R., Dirac A.M., Sixma T.K., and Bernards R. A genomic and functional inventory of deubiquitinating enzymes. Cell 123 (2005) 773-786
7. Nakamura N., and Hirose S. Regulation of mitochondrial morphology by USP30, a deubiquitinating enzyme present in the mitochondrial outer membrane. Mol. Biol. Cell 19 (2008) 1903-1911
8. Jeffers M., Taylor G.A., Weidner K.M., Omura S., and Vande Woude G.F. Degradation of the Met tyrosine kinase receptor by the ubiquitin-proteasome pathway. Mol. Cell. Biol. 17 (1997) 799-808
9. Hammond D.E., Urbe S., Vande Woude G.F., and Clague M.J. Down-regulation of MET, the receptor for hepatocyte growth factor. Oncogene 20 (2001) 2761-2770
10. Potempa S., and Ridley A.J. Activation of both MAP kinase and phosphatidylinositide 3-kinase by Ras is required for hepatocyte growth factor/scatter factor-induced adherens junction disassembly. Mol. Biol. Cell 9 (1998) 2185-2200
11. Bayascas J.R., and Alessi D.R. Regulation of Akt/PKB Ser473 phosphorylation. Mol. Cell 18 (2005) 143-145
12. Chen H.C., Chan P.C., Tang M.J., Cheng C.H., and Chang T.J. Tyrosine phosphorylation of focal adhesion kinase stimulated by hepatocyte growth factor leads to mitogen-activated protein kinase activation. J. Biol. Chem. 273 (1998) 25777-25782
13. Lai J.F., Kao S.C., Jiang S.T., Tang M.J., Chan P.C., and Chen H.C. Involvement of focal adhesion kinase in hepatocyte growth factor-induced scatter of Madin-Darby canine kidney cells. J. Biol. Chem. 275 (2000) 7474-7480
14. Li Z., Na X., Wang D., Schoen S.R., Messing E.M., and Wu G. Ubiquitination of a novel deubiquitinating enzyme requires direct binding to von Hippel-Lindau tumor suppressor protein. J. Biol. Chem. 277 (2002) 4656-4662
15. Enesa K., Zakkar M., Chaudhury H., Luong le A., Rawlinson L., Mason J.C., Haskard D.O., Dean J.L., and Evans P.C. NF-kappaB suppression by the deubiquitinating enzyme Cezanne: A novel negative feedback loop in pro-inflammatory signaling. J. Biol. Chem. 283 (2008) 7036-7045
16. Huang T.T., Nijman S.M., Mirchandani K.D., Galardy P.J., Cohn M.A., Haas W., Gygi S.P., Ploegh H.L., Bernards R., and D'Andrea A.D. Regulation of monoubiquitinated PCNA by DUB autocleavage. Nat. Cell Biol. 8 (2006) 339-347
17. Nijman S.M., Huang T.T., Dirac A.M., Brummelkamp T.R., Kerkhoven R.M., D'Andrea A.D., and Bernards R. The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway. Mol. Cell 17 (2005) 331-339
18. Alexandru G., Graumann J., Smith G.T., Kolawa N.J., Fang R., and Deshaies R.J. UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover. Cell 134 (2008) 804-816
19. Quesada V., Diaz-Perales A., Gutierrez-Fernandez A., Garabaya C., Cal S., and Lopez-Otin C. Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases. Biochem. Biophys. Res. Commun. 314 (2004) 54-62
20. Seliger B., Fedorushchenko A., Brenner W., Ackermann A., Atkins D., Hanash S., and Lichtenfels R. Ubiquitin COOH-terminal hydrolase 1: A biomarker of renal cell carcinoma associated with enhanced tumor cell proliferation and migration. Clin. Cancer Res. 13 (2007) 27-37
21. Masuda-Robens J.M., Kutney S.N., Qi H., and Chou M.M. The TRE17 oncogene encodes a component of a novel effector pathway for Rho GTPases Cdc42 and Rac1 and stimulates actin remodeling. Mol. Cell. Biol. 23 (2003) 2151-2161
22. Martinu L., Masuda-Robens J.M., Robertson S.E., Santy L.C., Casanova J.E., and Chou M.M. The TBC (Tre-2/Bub2/Cdc16) domain protein TRE17 regulates plasma membrane-endosomal trafficking through activation of Arf6. Mol. Cell. Biol. 24 (2004) 9752-9762
23. Carter S., Urbe S., and Clague M.J. The met receptor degradation pathway: Requirement for Lys48-linked polyubiquitin independent of proteasome activity. J. Biol. Chem. 279 (2004) 52835-52839
24. Mukhopadhyay D., and Riezman H. Proteasome-independent functions of ubiquitin in endocytosis and signaling. Science 315 (2007) 201-205
25. Daviet L., and Colland F. Targeting ubiquitin specific proteases for drug discovery. Biochimie 90 (2008) 270-283