Rab 1 A over-expression prevents golgi apparatus fragmentation and partially corrects motor deficits in an alpha-synuclein based rat model of Parkinson's disease

Journal of Parkinson's Disease

Volumn 1, Issue 4, 2011, Pages 373-387

  Coune, P G ^a   Bensadoun, J C ^a   Aebischer, P ^a   Schneider, B L ^a  

^a EPFL   (Switzerland)

Author keywords

adeno associated viral vector; Alpha synuclein; Golgi apparatus; motor behavior; Parkinson's disease; Rab 1 A; substantia nigra

Indexed keywords

ALPHA SYNUCLEIN; RAB1A PROTEIN; REGULATOR PROTEIN; UNCLASSIFIED DRUG; APOMORPHINE; DIAGNOSTIC AGENT; RAB PROTEIN; TYROSINE 3 MONOOXYGENASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CELL DAMAGE; CELL LOSS; CELL MIGRATION; CELL POPULATION; CELL STRUCTURE; CELL SURVIVAL; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; DOWN REGULATION; ENDOPLASMIC RETICULUM STRESS; FEMALE; GENE TRANSFER; GOLGI COMPLEX; LOCOMOTION; MOTOR CONTROL; MOTOR DYSFUNCTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PARKINSON DISEASE; PARKINSONISM; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN UNFOLDING; RAT; SECRETORY PATHWAY; SIGNAL TRANSDUCTION; SUBSTANTIA NIGRA PARS COMPACTA; ANIMAL; DISEASE MODEL; DRUG EFFECT; EXPLORATORY BEHAVIOR; FORELIMB; GENE VECTOR; GENETICS; HUMAN; MALE; METABOLISM; MOUSE; MUTATION; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT; SUBSTANTIA NIGRA; TIME; ULTRASTRUCTURE;

ALPHA-SYNUCLEIN; ANIMALS; APOMORPHINE; DISEASE MODELS, ANIMAL; DOPAMINERGIC NEURONS; EXPLORATORY BEHAVIOR; FEMALE; FORELIMB; GENETIC VECTORS; GOLGI APPARATUS; HUMANS; MALE; MICE; MUTATION; PARKINSON DISEASE; RAB1 GTP-BINDING PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; SUBSTANTIA NIGRA; TIME FACTORS; TYROSINE 3-MONOOXYGENASE;

EID: 84857834456     PISSN: 18777171     EISSN: 1877718X     Source Type: Journal    
DOI: 10.3233/JPD-2011-11058     Document Type: Article

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