Statins as anti-inflammatory agents in atherogenesis: Molecular mechanisms and lessons from the recent clinical trials

Current Pharmaceutical Design

Volumn 18, Issue 11, 2012, Pages 1519-1530

  Antonopoulos, Alexios S ^a   Margaritis, Marios ^a   Lee, Regent ^a   Channon, Keith ^a   Antoniades, Charalambos ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Atherosclerosis; Coronary heart disease; Endothelial nitric oxide synthase; Heart failure; Inflammation; Outcome; Statins; Vascular redox

Indexed keywords

ANTIINFLAMMATORY AGENT; ATORVASTATIN; C REACTIVE PROTEIN; CERIVASTATIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; FIBRIC ACID DERIVATIVE; FLUINDOSTATIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MEVALONIC ACID; MEVINOLIN; N(G),N(G) DIMETHYLARGININE; NICOTINIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PITAVASTATIN; PRAVASTATIN; RAC1 PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; ROSUVASTATIN; SIMVASTATIN;

ACUTE CORONARY SYNDROME; ACUTE HEART INFARCTION; ADD ON THERAPY; ALLERGIC ASTHMA; ALZHEIMER DISEASE; ANTIINFLAMMATORY ACTIVITY; ATHEROGENESIS; CARDIOVASCULAR RISK; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CHRONIC KIDNEY DISEASE; CORONARY ARTERY ATHEROSCLEROSIS; CORONARY ARTERY DISEASE; CYTOKINE PRODUCTION; DIABETES MELLITUS; DOWN REGULATION; DRUG WITHDRAWAL; GENE EXPRESSION; HEART FAILURE; HEART MUSCLE FIBROSIS; HUMAN; HYPERCHOLESTEROLEMIA; HYPERTENSION; IMMUNOMODULATION; ISCHEMIC HEART DISEASE; MULTIPLE SCLEROSIS; NONHUMAN; OSTEOPOROSIS; OXIDATION REDUCTION STATE; PARKINSON DISEASE; PERICARDIAL EFFUSION; PERICARDITIS; PLEIOTROPY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PRENYLATION; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; RHEUMATIC DISEASE; SIGNAL TRANSDUCTION; STROKE; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; THROMBOCYTE AGGREGATION INHIBITION; UNSPECIFIED SIDE EFFECT; UNSTABLE ANGINA PECTORIS; UPREGULATION; VIRUS MYOCARDITIS;

EID: 84857694797     PISSN: 13816128     EISSN: 18734286     Source Type: Journal    
DOI: 10.2174/138161212799504803     Document Type: Review

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