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Volumn 43, Issue 3, 2004, Pages 333-340

Simvastatin Enhances the Regeneration of Endothelial Cells via VEGF Secretion in Injured Arteries

Author keywords

Endothelial cell; Statin; Vascular remodeling; VEGF

Indexed keywords

DNA; RECEPTOR ANTIBODY; SIMVASTATIN; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN ANTIBODY; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 1 ANTIBODY; VASCULOTROPIN RECEPTOR 2; VASCULOTROPIN RECEPTOR 2 ANTIBODY;

EID: 1442302282     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-200403000-00002     Document Type: Article
Times cited : (42)

References (37)
  • 1
    • 0032585608 scopus 로고    scopus 로고
    • Effect of HMG-CoA reductase inhibitors on coronary artery disease as assessed by electron-beam computed tomography
    • Callister TQ, Raggi P, Cooil B, et al. Effect of HMG-CoA reductase inhibitors on coronary artery disease as assessed by electron-beam computed tomography. N Engl J Med. 1998;31:339:1972-1978.
    • (1998) N Engl J Med , vol.339 , Issue.31 , pp. 1972-1978
    • Callister, T.Q.1    Raggi, P.2    Cooil, B.3
  • 2
    • 0342981862 scopus 로고    scopus 로고
    • The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels
    • Cholesterol and Recurrent Events Trial investigators
    • Sacks FM, Pfeffer MA, Moye LA, et al. The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events Trial investigators. N Engl J Med. 1996;335:1001-1009.
    • (1996) N Engl J Med , vol.335 , pp. 1001-1009
    • Sacks, F.M.1    Pfeffer, M.A.2    Moye, L.A.3
  • 3
    • 17344385569 scopus 로고    scopus 로고
    • Functional evaluation of lipid-lowering therapy by pravastatin
    • Schoebel FC, Jax TW, Strauer BE, et al. Functional evaluation of lipid-lowering therapy by pravastatin. Circulation. 1998;97:1874-1875.
    • (1998) Circulation , vol.97 , pp. 1874-1875
    • Schoebel, F.C.1    Jax, T.W.2    Strauer, B.E.3
  • 4
    • 0032555154 scopus 로고    scopus 로고
    • Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase
    • Endres M, Laufs U, Huang Z, et al. Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase. Proc Natl Acad Sci USA. 1998;95:8880-8885.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 8880-8885
    • Endres, M.1    Laufs, U.2    Huang, Z.3
  • 5
    • 0032487342 scopus 로고    scopus 로고
    • 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors increase fibrinolytic activity in rat aortic endothelial cells. Role of geranylgeranylation and Rho proteins
    • Essig M, Nguyen G, Prie D, et al. 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors increase fibrinolytic activity in rat aortic endothelial cells. Role of geranylgeranylation and Rho proteins. Circ Res. 1998;83:683-690.
    • (1998) Circ Res , vol.83 , pp. 683-690
    • Essig, M.1    Nguyen, G.2    Prie, D.3
  • 6
    • 0035010820 scopus 로고    scopus 로고
    • Effect of atorvastatin on plasminogen activator inhibitor type-1 synthesis in human monocytes/macrophages
    • Lopez S, Peiretti F, Bonardo B, et al. Effect of atorvastatin on plasminogen activator inhibitor type-1 synthesis in human monocytes/macrophages. J Cardiovasc Pharmacol. 2001;37:762-768.
    • (2001) J Cardiovasc Pharmacol , vol.37 , pp. 762-768
    • Lopez, S.1    Peiretti, F.2    Bonardo, B.3
  • 7
    • 0035380624 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibition protects the diabetic myocardium from ischemia-reperfusion injury
    • Lefer DJ, Scalia R, Jones SP, et al. HMG-CoA reductase inhibition protects the diabetic myocardium from ischemia-reperfusion injury. FASEB J. 2001;15:1454-1456.
    • (2001) FASEB J , vol.15 , pp. 1454-1456
    • Lefer, D.J.1    Scalia, R.2    Jones, S.P.3
  • 8
    • 0033398822 scopus 로고    scopus 로고
    • Simvastatin inhibits leukocyte-endothelial cell interactions and protects against inflammatory processes in normocholesterolemic rats
    • Pruefer D, Scalia R, Lefer AM. Simvastatin inhibits leukocyte-endothelial cell interactions and protects against inflammatory processes in normocholesterolemic rats. Arterioscler Thromb Vasc Biol. 1999;19:2894-2900.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 2894-2900
    • Pruefer, D.1    Scalia, R.2    Lefer, A.M.3
  • 9
    • 0033614802 scopus 로고    scopus 로고
    • Cholesterol reduction rapidly improves endothelial function after acute coronary syndromes. The RECIFE (reduction of cholesterol in ischemia and function of the endothelium) trial
    • Dupuis J, Tardif JC, Cernacek P, et al. Cholesterol reduction rapidly improves endothelial function after acute coronary syndromes. The RECIFE (reduction of cholesterol in ischemia and function of the endothelium) trial. Circulation. 1999;99:3227-3233.
    • (1999) Circulation , vol.99 , pp. 3227-3233
    • Dupuis, J.1    Tardif, J.C.2    Cernacek, P.3
  • 10
    • 0033536021 scopus 로고    scopus 로고
    • Improvement in coronary flow reserve determined by positron emission tomography after 6 months of cholesterol-lowering therapy in patients with early stages of coronary atherosclerosis
    • Baller D, Notohamiprodjo G, Gleichmann U, et al. Improvement in coronary flow reserve determined by positron emission tomography after 6 months of cholesterol-lowering therapy in patients with early stages of coronary atherosclerosis. Circulation. 1999;99:2871-2875.
    • (1999) Circulation , vol.99 , pp. 2871-2875
    • Baller, D.1    Notohamiprodjo, G.2    Gleichmann, U.3
  • 11
    • 0024816246 scopus 로고
    • Isolation and characterization of a newly identified endothelial cell mitogen produced by AtT-20 cells
    • Plouet J, Schilling J, Gospodarowicz D. Isolation and characterization of a newly identified endothelial cell mitogen produced by AtT-20 cells. EMBO J. 1989;8:3801-3806.
    • (1989) EMBO J , vol.8 , pp. 3801-3806
    • Plouet, J.1    Schilling, J.2    Gospodarowicz, D.3
  • 12
    • 0036144374 scopus 로고    scopus 로고
    • Lymphatic endothelium: A new frontier of metastasis research
    • Karkkainen MJ, Makinen T, Alitalo K. Lymphatic endothelium: a new frontier of metastasis research. Nat Cell Biol. 2002;4:E2-E5.
    • (2002) Nat Cell Biol , vol.4
    • Karkkainen, M.J.1    Makinen, T.2    Alitalo, K.3
  • 13
    • 0030004485 scopus 로고    scopus 로고
    • Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene
    • Ferrara N, Carver-Moore K, Chen H, et al. Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene. Nature. 1996;380:439-442.
    • (1996) Nature , vol.380 , pp. 439-442
    • Ferrara, N.1    Carver-Moore, K.2    Chen, H.3
  • 14
    • 0036242881 scopus 로고    scopus 로고
    • Co-expression of endothelin-1 and vascular endothelial growth factor mediates increased vascular permeability in lung grafts before reperfusion
    • Taghavi S, Abraham D, Riml P, et al. Co-expression of endothelin-1 and vascular endothelial growth factor mediates increased vascular permeability in lung grafts before reperfusion. J Heart Lung Transplant. 2002;21:600-603.
    • (2002) J Heart Lung Transplant , vol.21 , pp. 600-603
    • Taghavi, S.1    Abraham, D.2    Riml, P.3
  • 15
    • 0036771735 scopus 로고    scopus 로고
    • Lack of alpha2-antiplasmin promotes pulmonary heart failure via overrelease of VEGF after acute myocardial infarction
    • Matsuno H, Kozawa O, Yoshimi N, et al. Lack of alpha2-antiplasmin promotes pulmonary heart failure via overrelease of VEGF after acute myocardial infarction. Blood. 2002;100:2487-2493.
    • (2002) Blood , vol.100 , pp. 2487-2493
    • Matsuno, H.1    Kozawa, O.2    Yoshimi, N.3
  • 16
    • 0036849437 scopus 로고    scopus 로고
    • Vascular endothelial growth factor induces chemotaxis and proliferation of microglial cells
    • Forstreuter F, Lucius R, Mentlein R. Vascular endothelial growth factor induces chemotaxis and proliferation of microglial cells. J Neuroimmunol. 2002;132:93-98.
    • (2002) J Neuroimmunol , vol.132 , pp. 93-98
    • Forstreuter, F.1    Lucius, R.2    Mentlein, R.3
  • 17
    • 0036072098 scopus 로고    scopus 로고
    • Divergence of angiogenic and vascular permeability signaling by VEGF: Inhibition of protein kinase C suppresses VEGF-induced angiogenesis, but promotes VEGF-induced, NO-dependent vascular permeability
    • Spyridopoulos I, Luedemann C, Chen D, et al. Divergence of angiogenic and vascular permeability signaling by VEGF: inhibition of protein kinase C suppresses VEGF-induced angiogenesis, but promotes VEGF-induced, NO-dependent vascular permeability. Arterioscler Thromb Vasc Biol. 2002;22:901-906.
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 901-906
    • Spyridopoulos, I.1    Luedemann, C.2    Chen, D.3
  • 18
    • 0030750143 scopus 로고    scopus 로고
    • Related articles, insights in vessel development and vascular disorders using targeted inactivation and transfer of vascular endothelial growth factor, the tissue factor receptor, and the plasminogen system
    • Carmeliet P, Moons L, Dewerchin M, et al. Related articles, insights in vessel development and vascular disorders using targeted inactivation and transfer of vascular endothelial growth factor, the tissue factor receptor, and the plasminogen system. Ann N Y Acad Sci. 1997;811:191-206.
    • (1997) Ann N Y Acad Sci , vol.811 , pp. 191-206
    • Carmeliet, P.1    Moons, L.2    Dewerchin, M.3
  • 19
    • 0029028527 scopus 로고
    • Local delivery of vascular endothelial growth factor accelerates reendothelialization and attenuates intimal hyperplasia in balloon-injured rat carotid artery
    • Asahara T, Bauters C, Pastore C, et al. Local delivery of vascular endothelial growth factor accelerates reendothelialization and attenuates intimal hyperplasia in balloon-injured rat carotid artery. Circulation. 1995;91:2793-2801.
    • (1995) Circulation , vol.91 , pp. 2793-2801
    • Asahara, T.1    Bauters, C.2    Pastore, C.3
  • 20
    • 0035108560 scopus 로고    scopus 로고
    • Vein adaptation to arterialization in an experimental model
    • Westerband A, Crouse D, Richter LC, et al. Vein adaptation to arterialization in an experimental model. J Vasc Surg. 2001;33:561-569.
    • (2001) J Vasc Surg , vol.33 , pp. 561-569
    • Westerband, A.1    Crouse, D.2    Richter, L.C.3
  • 21
    • 0028935780 scopus 로고
    • Protein lipidation in cell signaling
    • Casey PJ. Protein lipidation in cell signaling. Science. 1995;268:221-225.
    • (1995) Science , vol.268 , pp. 221-225
    • Casey, P.J.1
  • 22
    • 0036645435 scopus 로고    scopus 로고
    • Simvastatin reduces neointimal thickening in low-density lipoprotein receptor-deficient mice after experimental angioplasty without changing plasma lipids
    • Chen Z, Fukutomi T, Zago AC, et al. Simvastatin reduces neointimal thickening in low-density lipoprotein receptor-deficient mice after experimental angioplasty without changing plasma lipids. Circulation. 2002;106:20-23.
    • (2002) Circulation , vol.106 , pp. 20-23
    • Chen, Z.1    Fukutomi, T.2    Zago, A.C.3
  • 23
    • 0037474528 scopus 로고    scopus 로고
    • Simvastatin stimulates VEGF release via p44/p42 MAP kinase in vascular smooth muscle cells
    • Takenaka M, Hirade K, Tanabe K, et al. Simvastatin stimulates VEGF release via p44/p42 MAP kinase in vascular smooth muscle cells. Biochem Biophys Res Commun. 2003;301:198-203.
    • (2003) Biochem Biophys Res Commun , vol.301 , pp. 198-203
    • Takenaka, M.1    Hirade, K.2    Tanabe, K.3
  • 24
    • 0030761798 scopus 로고    scopus 로고
    • Inhibition of von Willebrand factor binding to platelet GP Ib by a fractionated aurintricarboxylic acid prevents restenosis after vascular injury in hamster carotid artery
    • Matsuno H, Kozawa O, Niwa M, et al. Inhibition of von Willebrand factor binding to platelet GP Ib by a fractionated aurintricarboxylic acid prevents restenosis after vascular injury in hamster carotid artery. Circulation. 1997;96:1299-1304.
    • (1997) Circulation , vol.96 , pp. 1299-1304
    • Matsuno, H.1    Kozawa, O.2    Niwa, M.3
  • 25
    • 0030781335 scopus 로고    scopus 로고
    • GR144053, a fibrinogen receptor antagonist, enhances the suppression of neointima formation by losartan, an angiotensin II receptor antagonist, in the injured carotid artery of hamster
    • Matsuno H, Kozawa O, Niwa M, et al. GR144053, a fibrinogen receptor antagonist, enhances the suppression of neointima formation by losartan, an angiotensin II receptor antagonist, in the injured carotid artery of hamster. Br J Pharmacol. 1997;122:1099-1104.
    • (1997) Br J Pharmacol , vol.122 , pp. 1099-1104
    • Matsuno, H.1    Kozawa, O.2    Niwa, M.3
  • 26
    • 0034739554 scopus 로고    scopus 로고
    • Intravascular adenovirus-mediated VEGF-C gene transfer reduces neointima formation in balloon-denuded rabbit aorta
    • Hiltunen MO, Laitinen M, Turunen MP, et al. Intravascular adenovirus-mediated VEGF-C gene transfer reduces neointima formation in balloon-denuded rabbit aorta. Circulation. 2000;102:2262-2268.
    • (2000) Circulation , vol.102 , pp. 2262-2268
    • Hiltunen, M.O.1    Laitinen, M.2    Turunen, M.P.3
  • 27
    • 0033604614 scopus 로고    scopus 로고
    • Signaling via vascular endothelial growth factor receptors
    • Petrova TV, Makinen T, Alitalo K. Signaling via vascular endothelial growth factor receptors. Exp Cell Res. 1999;253:117-130.
    • (1999) Exp Cell Res , vol.253 , pp. 117-130
    • Petrova, T.V.1    Makinen, T.2    Alitalo, K.3
  • 28
    • 0032431037 scopus 로고    scopus 로고
    • Systemic hypoxia changes the organ-specific distribution of vascular endothelial growth factor and its receptors
    • Marti HH, Risau W. Systemic hypoxia changes the organ-specific distribution of vascular endothelial growth factor and its receptors. Proc Natl Acad Sci U S A. 1998;95:15809-15814.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 15809-15814
    • Marti, H.H.1    Risau, W.2
  • 29
    • 0029028527 scopus 로고
    • Local delivery of vascular endothelial growth factor accelerates reendothelialization and attenuates intimal hyperplasia in balloon-injured rat carotid artery
    • Asahara T, Bauters C, Pastore C, et al. Local delivery of vascular endothelial growth factor accelerates reendothelialization and attenuates intimal hyperplasia in balloon-injured rat carotid artery. Circulation. 1995;91:2793-2801.
    • (1995) Circulation , vol.91 , pp. 2793-2801
    • Asahara, T.1    Bauters, C.2    Pastore, C.3
  • 30
    • 0033600534 scopus 로고    scopus 로고
    • Antibody blockade of thrombospondin accelerates reendothelialization and reduces neointima formation in balloon-injured rat carotid artery
    • Chen D, Asahara T, Krasinski K, et al. Antibody blockade of thrombospondin accelerates reendothelialization and reduces neointima formation in balloon-injured rat carotid artery. Circulation. 1999;100:849-854.
    • (1999) Circulation , vol.100 , pp. 849-854
    • Chen, D.1    Asahara, T.2    Krasinski, K.3
  • 31
    • 0037065914 scopus 로고    scopus 로고
    • Statins have biphasic effects on angiogenesis
    • Weis M, Heeschen C, Glassford AJ, et al. Statins have biphasic effects on angiogenesis. Circulation. 2002;105:739-745.
    • (2002) Circulation , vol.105 , pp. 739-745
    • Weis, M.1    Heeschen, C.2    Glassford, A.J.3
  • 32
    • 0037178736 scopus 로고    scopus 로고
    • 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors interfere with angiogenesis by inhibiting the geranylgeranylation of RhoA
    • Park HJ, Kong D, Iruela-Arispe L, et al. 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors interfere with angiogenesis by inhibiting the geranylgeranylation of RhoA. Circ Res. 2002;91:143-150.
    • (2002) Circ Res , vol.91 , pp. 143-150
    • Park, H.J.1    Kong, D.2    Iruela-Arispe, L.3
  • 33
    • 0035062394 scopus 로고    scopus 로고
    • The splice variants of vascular endothelial growth factor (VEGF) and their receptors
    • Robinson CJ, Stringer SE. The splice variants of vascular endothelial growth factor (VEGF) and their receptors. J Cell Sci. 2001;114:853-865.
    • (2001) J Cell Sci , vol.114 , pp. 853-865
    • Robinson, C.J.1    Stringer, S.E.2
  • 34
    • 0036079448 scopus 로고    scopus 로고
    • Inhibition of vascular endothelial growth factor-mediated neointima progression with angiostatin or paclitaxel
    • Celletti FL, Waugh JM, Amabile PG, et al. Inhibition of vascular endothelial growth factor-mediated neointima progression with angiostatin or paclitaxel. J Vasc Interv Radiol. 2002;13:703-707.
    • (2002) J Vasc Interv Radiol , vol.13 , pp. 703-707
    • Celletti, F.L.1    Waugh, J.M.2    Amabile, P.G.3
  • 35
    • 0032588506 scopus 로고    scopus 로고
    • Genetech enlightens other angiogenesis programs
    • Brower V. Genetech enlightens other angiogenesis programs. Nat Biotechnol. 1999;17:326-327.
    • (1999) Nat Biotechnol , vol.17 , pp. 326-327
    • Brower, V.1
  • 36
    • 0026505773 scopus 로고
    • Molecular and biological properties of the vascular endothelial growth factor family of proteins
    • Ferrara N, Houck K, Jakeman L, et al. Molecular and biological properties of the vascular endothelial growth factor family of proteins. Endocr Rev. 1992;13:18-32.
    • (1992) Endocr Rev , vol.13 , pp. 18-32
    • Ferrara, N.1    Houck, K.2    Jakeman, L.3
  • 37
    • 0036771735 scopus 로고    scopus 로고
    • Lack of alpha2-antiplasmin promotes pulmonary heart failure via overrelease of VEGF after acute myocardial infarction
    • Matsuno H, Kozawa O, Yoshimi N, et al. Lack of alpha2-antiplasmin promotes pulmonary heart failure via overrelease of VEGF after acute myocardial infarction. Blood. 2002;100:2487-2493.
    • (2002) Blood , vol.100 , pp. 2487-2493
    • Matsuno, H.1    Kozawa, O.2    Yoshimi, N.3


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