메뉴 건너뛰기




Volumn 363, Issue 9426, 2004, Pages 2015-2021

Trial of Atorvastatin in Rheumatoid Arthritis (TARA): Double-blind, randomised placebo-controlled trial

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRHEUMATIC AGENT; ATORVASTATIN; C REACTIVE PROTEIN; CORTICOSTEROID; DIHYDROQUINIDINE; GOLD; LEFLUNOMIDE; METHOTREXATE; MINOCYCLINE; PENICILLAMINE; PLACEBO; PREDNISOLONE; SALAZOSULFAPYRIDINE; TRIAMCINOLONE;

EID: 2942670131     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(04)16449-0     Document Type: Article
Times cited : (775)

References (36)
  • 1
    • 0028883828 scopus 로고
    • Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia
    • Shepherd JS, Cobbe SM, Ford I, et al. Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. N Engl J Med. 333:1995;1301-1307
    • (1995) N Engl J Med , vol.333 , pp. 1301-1307
    • Shepherd, J.S.1    Cobbe, S.M.2    Ford, I.3
  • 2
    • 0037031061 scopus 로고    scopus 로고
    • MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20 536 high-risk individuals: A randomised placebo-controlled trial
    • Heart Protection Study Collaborative Group. MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20 536 high-risk individuals: a randomised placebo-controlled trial. Lancet. 360:2002;7-22
    • (2002) Lancet , vol.360 , pp. 7-22
  • 3
    • 0037420492 scopus 로고    scopus 로고
    • Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial-Lipid Lowering Arm (ASCOT-LLA): A multicentre randomised controlled trial
    • Sever PS, Dahlöf B, Poulter NR, et al. Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial-Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial. Lancet. 361:2003;1149-1158
    • (2003) Lancet , vol.361 , pp. 1149-1158
    • Sever, P.S.1    Dahlöf, B.2    Poulter, N.R.3
  • 5
    • 0036847038 scopus 로고    scopus 로고
    • Unraveling pleiotropic effects of statins on plaque rupture
    • Palinski W, Napoli C. Unraveling pleiotropic effects of statins on plaque rupture. Arterioscler Thromb Vasc Biol. 22:2002;1745-1750
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 1745-1750
    • Palinski, W.1    Napoli, C.2
  • 6
    • 0036229685 scopus 로고    scopus 로고
    • Accelerated atherosclerosis: An extraarticular feature of rheumatoid arthritis?
    • Van Doornum S, McColl G, Wicks IP. Accelerated atherosclerosis: an extraarticular feature of rheumatoid arthritis? Arthritis Rheum. 46:2002;862-873
    • (2002) Arthritis Rheum , vol.46 , pp. 862-873
    • Van Doornum, S.1    McColl, G.2    Wicks, I.P.3
  • 7
    • 0346365086 scopus 로고    scopus 로고
    • Explaining how "high-grade" systemic inflammation accelerates vascular risk in rheumatoid arthritis
    • Sattar N, McCarey DW, Capell H, McInnes IB. Explaining how "high-grade" systemic inflammation accelerates vascular risk in rheumatoid arthritis. Circulation. 108:2003;2957-2963
    • (2003) Circulation , vol.108 , pp. 2957-2963
    • Sattar, N.1    McCarey, D.W.2    Capell, H.3    McInnes, I.B.4
  • 8
    • 0037309378 scopus 로고    scopus 로고
    • A novel anti-inflammatory role for simvastatin in inflammatory arthritis
    • Leung BP, Sattar N, Crilly A, et al. A novel anti-inflammatory role for simvastatin in inflammatory arthritis. J Immunol. 170:2003;1524-1530
    • (2003) J Immunol , vol.170 , pp. 1524-1530
    • Leung, B.P.1    Sattar, N.2    Crilly, A.3
  • 9
    • 0037038402 scopus 로고    scopus 로고
    • The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease
    • Youssef S, Stuve O, Patarroyo JC, et al. The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease. Nature. 420:2002;78-84
    • (2002) Nature , vol.420 , pp. 78-84
    • Youssef, S.1    Stuve, O.2    Patarroyo, J.C.3
  • 10
    • 0026630114 scopus 로고
    • Prognostic factors for radiographic damage and physical disability in early rheumatoid arthritis: A prospective follow-up study of 147 patients
    • van der Heijde DMFM, van Riel PLCM, Leeuwen MA, van 't Hof MA, van Rijswijk MH, van de Putte LBA. Prognostic factors for radiographic damage and physical disability in early rheumatoid arthritis: a prospective follow-up study of 147 patients. Br J Rheumatol. 31:1992;519-525
    • (1992) Br J Rheumatol , vol.31 , pp. 519-525
    • Van Der Heijde, D.1    Van Riel, P.2    Leeuwen, M.A.3    Van 'T Hof, M.A.4    Van Rijswijk, M.H.5    Van De Putte, L.B.A.6
  • 11
    • 0028815803 scopus 로고
    • Modified disease activity scores that include twenty-eight-joint counts: Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis
    • Prevoo ML, van 't Hof MA, Kuper HH, van Leeuwen MA, van de Putte LB, van Riel PL. Modified disease activity scores that include twenty-eight-joint counts: development and validation in a prospective longitudinal study of patients with rheumatoid arthritis. Arthritis Rheum. 38:1995;44-48
    • (1995) Arthritis Rheum , vol.38 , pp. 44-48
    • Prevoo, M.L.1    Van 'T Hof, M.A.2    Kuper, H.H.3    Van Leeuwen, M.A.4    Van De Putte, L.B.5    Van Riel, P.L.6
  • 12
    • 0033019626 scopus 로고    scopus 로고
    • ACR and EULAR improvement criteria have comparable validity in rheumatoid arthritis trials
    • van Gestel AM, Anderson JJ, van Riel PL, et al. ACR and EULAR improvement criteria have comparable validity in rheumatoid arthritis trials. J Rheumatol. 26:1999;705-711
    • (1999) J Rheumatol , vol.26 , pp. 705-711
    • Van Gestel, A.M.1    Anderson, J.J.2    Van Riel, P.L.3
  • 13
    • 0034687446 scopus 로고    scopus 로고
    • Lipoprotein-associated phospholipase A2 as an independent predictor of coronary heart disease
    • Packard CJ, O'Reilly DS, Caslake MJ, et al. Lipoprotein-associated phospholipase A2 as an independent predictor of coronary heart disease. N Engl J Med. 343:2000;1148-1155
    • (2000) N Engl J Med , vol.343 , pp. 1148-1155
    • Packard, C.J.1    O'Reilly, D.S.2    Caslake, M.J.3
  • 14
    • 0037213448 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase inhibition by statins inhibits neutrophil activation by ANCA
    • Choi M, Rolle S, Rane M, Haller H, Luft FC, Kettritz R. Extracellular signal-regulated kinase inhibition by statins inhibits neutrophil activation by ANCA. Kidney Int. 63:2003;96-106
    • (2003) Kidney Int , vol.63 , pp. 96-106
    • Choi, M.1    Rolle, S.2    Rane, M.3    Haller, H.4    Luft, F.C.5    Kettritz, R.6
  • 15
    • 0034533147 scopus 로고    scopus 로고
    • Statins as a newly recognized type of immunomodulator
    • Kwak B, Mulhaupt F, Myit S, Mach F. Statins as a newly recognized type of immunomodulator. Nat Med. 6:2000;1399-1402
    • (2000) Nat Med , vol.6 , pp. 1399-1402
    • Kwak, B.1    Mulhaupt, F.2    Myit, S.3    MacH, F.4
  • 16
    • 0034948339 scopus 로고    scopus 로고
    • Statins selectively inhibit leukocyte function antigen-1 by binding to a novel regulatory integrin site
    • Weitz-Schmidt G, Welzenbach K, Brinkmann V, et al. Statins selectively inhibit leukocyte function antigen-1 by binding to a novel regulatory integrin site. Nat Med. 7:2001;687-692
    • (2001) Nat Med , vol.7 , pp. 687-692
    • Weitz-Schmidt, G.1    Welzenbach, K.2    Brinkmann, V.3
  • 17
    • 0344013648 scopus 로고    scopus 로고
    • Inhibition of hydroxymethylglutaryl-coenzyme a reductase reduces Th1 development and promotes Th2 development
    • Hakamada-Taguchi R, Uehara Y, Kuribayashi K, et al. Inhibition of hydroxymethylglutaryl-coenzyme a reductase reduces Th1 development and promotes Th2 development. Circ Res. 93:2003;948-956
    • (2003) Circ Res , vol.93 , pp. 948-956
    • Hakamada-Taguchi, R.1    Uehara, Y.2    Kuribayashi, K.3
  • 18
    • 0035162266 scopus 로고    scopus 로고
    • Simvastatin has anti-inflammatory and antiatherosclerotic activities independent of plasma cholesterol lowering
    • Sparrow CP, Burton CA, Hernandez M, et al. Simvastatin has anti-inflammatory and antiatherosclerotic activities independent of plasma cholesterol lowering. Arterioscler Thromb Vasc Biol. 21:2001;115-121
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 115-121
    • Sparrow, C.P.1    Burton, C.A.2    Hernandez, M.3
  • 19
    • 0037210127 scopus 로고    scopus 로고
    • Protective effect of HMG-CoA reductase inhibitor on experimental renal ischemia-reperfusion injury
    • Yokota N, O'Donnell M, Daniels F, et al. Protective effect of HMG-CoA reductase inhibitor on experimental renal ischemia-reperfusion injury. Am J Nephrol. 23:2003;13-17
    • (2003) Am J Nephrol , vol.23 , pp. 13-17
    • Yokota, N.1    O'Donnell, M.2    Daniels, F.3
  • 20
    • 0242349750 scopus 로고    scopus 로고
    • Direct anti-inflammatory mechanisms contribute to attenuation of experimental allograft arteriosclerosis by statins
    • Shimizu K, Aikawa M, Takayama K, Libby P, Mitchell RN. Direct anti-inflammatory mechanisms contribute to attenuation of experimental allograft arteriosclerosis by statins. Circulation. 108:2003;2113-2120
    • (2003) Circulation , vol.108 , pp. 2113-2120
    • Shimizu, K.1    Aikawa, M.2    Takayama, K.3    Libby, P.4    Mitchell, R.N.5
  • 21
    • 0029022389 scopus 로고
    • Combination therapy with cyclosporine and methotrexate in severe rheumatoid arthritis
    • Tugwell P, Pincus T, Yocum D, et al. Combination therapy with cyclosporine and methotrexate in severe rheumatoid arthritis. N Engl J Med. 333:1995;137-141
    • (1995) N Engl J Med , vol.333 , pp. 137-141
    • Tugwell, P.1    Pincus, T.2    Yocum, D.3
  • 23
    • 10744223002 scopus 로고    scopus 로고
    • Therapeutic effect of the combination of etanercept and methotrexate compared with each treatment alone in patients with rheumatoid arthritis: Double-blind randomised controlled trial
    • Klareskog L, van der Heijde D, de Jager JP, et al. Therapeutic effect of the combination of etanercept and methotrexate compared with each treatment alone in patients with rheumatoid arthritis: double-blind randomised controlled trial. Lancet. 363:2004;675-681
    • (2004) Lancet , vol.363 , pp. 675-681
    • Klareskog, L.1    Van Der Heijde, D.2    De Jager, J.P.3
  • 24
    • 0035056003 scopus 로고    scopus 로고
    • Anti-TNF alpha therapy of rheumatoid arthritis: What have we learned?
    • Feldmann M, Maini RN. Anti-TNF alpha therapy of rheumatoid arthritis: what have we learned? Annu Rev Immunol. 19:2001;163-196
    • (2001) Annu Rev Immunol , vol.19 , pp. 163-196
    • Feldmann, M.1    Maini, R.N.2
  • 25
    • 0034082253 scopus 로고    scopus 로고
    • Factors predicting response to treatment in rheumatoid arthritis: The importance of disease duration
    • Anderson JJ, Wells G, Verhoeven AC, Felson DT. Factors predicting response to treatment in rheumatoid arthritis: the importance of disease duration. Arthritis Rheum. 43:2000;22-29
    • (2000) Arthritis Rheum , vol.43 , pp. 22-29
    • Anderson, J.J.1    Wells, G.2    Verhoeven, A.C.3    Felson, D.T.4
  • 26
    • 0037078969 scopus 로고    scopus 로고
    • Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events
    • Ridker PM, Rifai N, Rose L, Buring JE, Cook NR. Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events. N Engl J Med. 347:2002;1557-1565
    • (2002) N Engl J Med , vol.347 , pp. 1557-1565
    • Ridker, P.M.1    Rifai, N.2    Rose, L.3    Buring, J.E.4    Cook, N.R.5
  • 27
    • 10744224994 scopus 로고    scopus 로고
    • Interaction of oxidative stress and inflammatory response in coronary plaque instability: Important role of C-reactive protein
    • Kobayashi S, Inoue N, Ohashi Y, et al. Interaction of oxidative stress and inflammatory response in coronary plaque instability: important role of C-reactive protein. Arterioscler Thromb Vasc Biol. 23:2003;1398-1404
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 1398-1404
    • Kobayashi, S.1    Inoue, N.2    Ohashi, Y.3
  • 28
    • 0037469261 scopus 로고    scopus 로고
    • C-reactive protein increases plasminogen activator inhibitor-1 expression and activity in human aortic endothelial cells: Implications for the metabolic syndrome and atherothrombosis
    • Devaraj S, Xu DY, Jialal I. C-reactive protein increases plasminogen activator inhibitor-1 expression and activity in human aortic endothelial cells: implications for the metabolic syndrome and atherothrombosis. Circulation. 107:2003;398-404
    • (2003) Circulation , vol.107 , pp. 398-404
    • Devaraj, S.1    Xu, D.Y.2    Jialal, I.3
  • 29
    • 0037126012 scopus 로고    scopus 로고
    • Demonstration that C-reactive protein decreases eNOS expression and bioactivity in human aortic endothelial cells
    • Venugopal SK, Devaraj S, Yuhanna I, Shaul P, Jialal I. Demonstration that C-reactive protein decreases eNOS expression and bioactivity in human aortic endothelial cells. Circulation. 106:2002;1439-1441
    • (2002) Circulation , vol.106 , pp. 1439-1441
    • Venugopal, S.K.1    Devaraj, S.2    Yuhanna, I.3    Shaul, P.4    Jialal, I.5
  • 30
    • 0035814966 scopus 로고    scopus 로고
    • C-reactive protein-mediated low density lipoprotein uptake by macrophages: Implications for atherosclerosis
    • Zwaka TP, Hombach V, Torzewski J. C-reactive protein-mediated low density lipoprotein uptake by macrophages: implications for atherosclerosis. Circulation. 103:2001;1194-1197
    • (2001) Circulation , vol.103 , pp. 1194-1197
    • Zwaka, T.P.1    Hombach, V.2    Torzewski, J.3
  • 31
    • 17044454411 scopus 로고    scopus 로고
    • Effects of statins on C-reactive protein and interleukin-6 (the Ludwigshafen Risk and Cardiovascular Health study)
    • Marz W, Winkler K, Nauck M, Bohm BO, Winkelmann BR. Effects of statins on C-reactive protein and interleukin-6 (the Ludwigshafen Risk and Cardiovascular Health study). Am J Cardiol. 92:2003;305-308
    • (2003) Am J Cardiol , vol.92 , pp. 305-308
    • Marz, W.1    Winkler, K.2    Nauck, M.3    Bohm, B.O.4    Winkelmann, B.R.5
  • 32
    • 0037403080 scopus 로고    scopus 로고
    • Reduction of serum C-reactive protein by statin therapy may reflect decreased isoprenylation of Rac-1, a mediator of the IL-6 signal transduction pathway
    • McCarty MF. Reduction of serum C-reactive protein by statin therapy may reflect decreased isoprenylation of Rac-1, a mediator of the IL-6 signal transduction pathway. Med Hypotheses. 60:2003;634-639
    • (2003) Med Hypotheses , vol.60 , pp. 634-639
    • McCarty, M.F.1
  • 33
    • 0033984744 scopus 로고    scopus 로고
    • Inflammation, obesity, stress and coronary heart disease: Is interleukin-6 the link?
    • Yudkin JS, Kumari M, Humphries SE, Mohamed-Ali V. Inflammation, obesity, stress and coronary heart disease: is interleukin-6 the link? Atherosclerosis. 148:2000;209-214
    • (2000) Atherosclerosis , vol.148 , pp. 209-214
    • Yudkin, J.S.1    Kumari, M.2    Humphries, S.E.3    Mohamed-Ali, V.4
  • 34
    • 0036014951 scopus 로고    scopus 로고
    • Immunomodulatory effects of statins: Mechanisms and potential impact on arteriosclerosis
    • Palinski W, Tsimikas S. Immunomodulatory effects of statins: mechanisms and potential impact on arteriosclerosis. J Am Soc Nephrol. 13:2002;1673-1681
    • (2002) J Am Soc Nephrol , vol.13 , pp. 1673-1681
    • Palinski, W.1    Tsimikas, S.2
  • 35
    • 0037029418 scopus 로고    scopus 로고
    • Methotrexate and mortality in patients with rheumatoid arthritis: A prospective study
    • Choi HK, Hernan MA, Seeger JD, et al. Methotrexate and mortality in patients with rheumatoid arthritis: a prospective study. Lancet. 359:2002;1173-1177
    • (2002) Lancet , vol.359 , pp. 1173-1177
    • Choi, H.K.1    Hernan, M.A.2    Seeger, J.D.3
  • 36
    • 9144252008 scopus 로고    scopus 로고
    • Endothelial dysfunction in young patients with rheumatoid arthritis and low disease activity
    • Vaudo G, Marchesi S, Gerli R, et al. Endothelial dysfunction in young patients with rheumatoid arthritis and low disease activity. Ann Rheum Dis. 63:2004;31-35
    • (2004) Ann Rheum Dis , vol.63 , pp. 31-35
    • Vaudo, G.1    Marchesi, S.2    Gerli, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.