메뉴 건너뛰기




Volumn 298, Issue 1, 2010, Pages

Regulation of the ADMA-DDAH system in endothelial cells: A novel mechanism for the sterol response element binding proteins, SREBP1c and -2

Author keywords

Asymmetric dimethylarginine; Dimethylarginine dimethylaminohydrolase; Endothelial nitric oxide synthase

Indexed keywords

CHOLESTEROL; DIMETHYLARGININASE; MESSENGER RNA; N(G),N(G) DIMETHYLARGININE; SIMVASTATIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; STEROL REGULATORY ELEMENT BINDING PROTEIN 2;

EID: 73549110255     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00195.2009     Document Type: Article
Times cited : (35)

References (64)
  • 1
    • 0041733065 scopus 로고    scopus 로고
    • Asymmetric dimethylarginine causes hypertension and cardiac dysfunction in humans and is actively metabolized by dimethy-larginine dimethylaminohydrolase
    • Achan V, Broadhead M, Malaki M, Whitley G, Leiper J, MacAllister R, Vallance P. Asymmetric dimethylarginine causes hypertension and cardiac dysfunction in humans and is actively metabolized by dimethy-larginine dimethylaminohydrolase. Arterioscler Thromb Vasc Biol 23: 1455-1459, 2003.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 1455-1459
    • Achan, V.1    Broadhead, M.2    Malaki, M.3    Whitley, G.4    Leiper, J.5    MacAllister, R.6    Vallance, P.7
  • 2
    • 0037134408 scopus 로고    scopus 로고
    • all-trans-Retinoic acid increases nitric oxide synthesis by endothelial cells: A role for the induction of dimethylarginine dimethylaminohydrolase
    • Achan V, Tran CT, Arrigoni F, Whitley GS, Leiper JM, Vallance P. all-trans-Retinoic acid increases nitric oxide synthesis by endothelial cells: a role for the induction of dimethylarginine dimethylaminohydrolase. Circ Res 90: 764-769, 2002.
    • (2002) Circ Res , vol.90 , pp. 764-769
    • Achan, V.1    Tran, C.T.2    Arrigoni, F.3    Whitley, G.S.4    Leiper, J.M.5    Vallance, P.6
  • 3
    • 47049092561 scopus 로고    scopus 로고
    • Selective binding of SREBP isoforms and co-regulatory proteins to promoters for lipid metabolic genes in liver
    • Bennett MK, Seo YK, Datta S, Shin DJ, Osborne TF. Selective binding of SREBP isoforms and co-regulatory proteins to promoters for lipid metabolic genes in liver. J Biol Chem 283: 15628-15637, 2008.
    • (2008) J Biol Chem , vol.283 , pp. 15628-15637
    • Bennett, M.K.1    Seo, Y.K.2    Datta, S.3    Shin, D.J.4    Osborne, T.F.5
  • 4
    • 31344449586 scopus 로고    scopus 로고
    • Asymmetric dimethylarginine (ADMA) and cardiovascular disease: Insights from prospective clinical trials
    • Boger RH. Asymmetric dimethylarginine (ADMA) and cardiovascular disease: insights from prospective clinical trials. Vasc Med 10, Suppl 1: S19-S25, 2005.
    • (2005) Vasc Med , vol.10 , Issue.SUPPL. 1
    • Boger, R.H.1
  • 5
    • 0034698038 scopus 로고    scopus 로고
    • LDL cholesterol upregulates synthesis of asymmetrical dimethylarginine in human endothelial cells: Involvement of Sadenosylmethionine- dependent methyltransferases
    • Boger RH, Sydow K, Borlak J, Thum T, Lenzen H, Schubert B, Tsikas D, Bode-Boger SM. LDL cholesterol upregulates synthesis of asymmetrical dimethylarginine in human endothelial cells: involvement of Sadenosylmethionine- dependent methyltransferases. Circ Res 87: 99-105, 2000.
    • (2000) Circ Res , vol.87 , pp. 99-105
    • Boger, R.H.1    Sydow, K.2    Borlak, J.3    Thum, T.4    Lenzen, H.5    Schubert, B.6    Tsikas, D.7    Bode-Boger, S.M.8
  • 7
    • 33845522700 scopus 로고    scopus 로고
    • Statins reduce macrophage inflammatory protein-1alpha expression in human activated monocytes
    • Bruegel M, Teupser D, Haffner I, Mueller M, Thiery J. Statins reduce macrophage inflammatory protein-1alpha expression in human activated monocytes. Clin Exp Pharmacol Physiol 33: 1144-1149, 2006.
    • (2006) Clin Exp Pharmacol Physiol , vol.33 , pp. 1144-1149
    • Bruegel, M.1    Teupser, D.2    Haffner, I.3    Mueller, M.4    Thiery, J.5
  • 8
    • 0033813512 scopus 로고    scopus 로고
    • Does ADMA cause endothelial dysfunction?
    • Cooke JP. Does ADMA cause endothelial dysfunction? Arterioscler Thromb Vasc Biol 20: 2032-2037, 2000.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 2032-2037
    • Cooke, J.P.1
  • 9
    • 1242341462 scopus 로고    scopus 로고
    • NO and angiogenesis
    • Cooke JP. NO and angiogenesis. Atheroscler Suppl 4: 53-60, 2003.
    • (2003) Atheroscler Suppl , vol.4 , pp. 53-60
    • Cooke, J.P.1
  • 11
    • 38149020150 scopus 로고    scopus 로고
    • Overexpression of dimethylarginine dimethylaminohydrolase inhibits asymmetric dimethylarginine-induced endothelial dysfunction in the cerebral circulation
    • Dayoub H, Rodionov R, Lynch C, Cooke JP, Arning E, Bottiglieri T, Lentz SR, Faraci FM. Overexpression of dimethylarginine dimethylaminohydrolase inhibits asymmetric dimethylarginine-induced endothelial dysfunction in the cerebral circulation. Stroke 39: 180-184, 2008.
    • (2008) Stroke , vol.39 , pp. 180-184
    • Dayoub, H.1    Rodionov, R.2    Lynch, C.3    Cooke, J.P.4    Arning, E.5    Bottiglieri, T.6    Lentz, S.R.7    Faraci, F.M.8
  • 12
    • 12244268005 scopus 로고    scopus 로고
    • Increased levels of asymmetric dimethylarginine in populations at risk for atherosclerotic disease. Effects of pravastatin
    • Eid HM, Eritsland J, Larsen J, Arnesen H, Seljeflot I. Increased levels of asymmetric dimethylarginine in populations at risk for atherosclerotic disease. Effects of pravastatin. Atherosclerosis 166: 279-284, 2003.
    • (2003) Atherosclerosis , vol.166 , pp. 279-284
    • Eid, H.M.1    Eritsland, J.2    Larsen, J.3    Arnesen, H.4    Seljeflot, I.5
  • 13
    • 58049180113 scopus 로고    scopus 로고
    • Rosuvastatin prevents endothelial cell death and reduces atherosclerotic lesion formation in ApoE-deficient mice
    • Enomoto S, Sata M, Fukuda D, Nakamura K, Nagai R. Rosuvastatin prevents endothelial cell death and reduces atherosclerotic lesion formation in ApoE-deficient mice. Biomed Pharmacother 63: 19-26, 2007.
    • (2007) Biomed Pharmacother , vol.63 , pp. 19-26
    • Enomoto, S.1    Sata, M.2    Fukuda, D.3    Nakamura, K.4    Nagai, R.5
  • 17
    • 34547590325 scopus 로고    scopus 로고
    • Role of asymmetric dimethylarginine in vascular injury in transgenic mice overexpressing dimethylarginie dimethylaminohydrolase 2
    • Hasegawa K, Wakino S, Tatematsu S, Yoshioka K, Homma K, Sugano N, Kimoto M, Hayashi K, Itoh H. Role of asymmetric dimethylarginine in vascular injury in transgenic mice overexpressing dimethylarginie dimethylaminohydrolase 2. Circ Res 101: e2-e10, 2007.
    • (2007) Circ Res , vol.101
    • Hasegawa, K.1    Wakino, S.2    Tatematsu, S.3    Yoshioka, K.4    Homma, K.5    Sugano, N.6    Kimoto, M.7    Hayashi, K.8    Itoh, H.9
  • 18
    • 33846027539 scopus 로고    scopus 로고
    • Farnesoid X receptor agonist reduces serum asymmetric dimethylarginine levels through hepatic dimethylarginine dimethylaminohydrolase-1 gene regulation
    • Hu T, Chouinard M, Cox AL, Sipes P, Marcelo M, Ficorilli J, Li S, Gao H, Ryan TP, Michael MD, Michael LF. Farnesoid X receptor agonist reduces serum asymmetric dimethylarginine levels through hepatic dimethylarginine dimethylaminohydrolase-1 gene regulation. J Biol Chem 281: 39831-39838, 2006.
    • (2006) J Biol Chem , vol.281 , pp. 39831-39838
    • Hu, T.1    Chouinard, M.2    Cox, A.L.3    Sipes, P.4    Marcelo, M.5    Ficorilli, J.6    Li, S.7    Gao, H.8    Ryan, T.P.9    Michael, M.D.10    Michael, L.F.11
  • 20
    • 0034687141 scopus 로고    scopus 로고
    • Angiogenesis is impaired by hypercholesterolemia: Role of asymmetric dimethylarginine
    • Jang JJ, Ho HK, Kwan HH, Fajardo LF, Cooke JP. Angiogenesis is impaired by hypercholesterolemia: role of asymmetric dimethylarginine. Circulation 102: 1414-1419, 2000.
    • (2000) Circulation , vol.102 , pp. 1414-1419
    • Jang, J.J.1    Ho, H.K.2    Kwan, H.H.3    Fajardo, L.F.4    Cooke, J.P.5
  • 21
    • 0029795806 scopus 로고    scopus 로고
    • Central and peripheral effects of asymmetric dimethylarginine, an endogenous nitric oxide synthetase inhibitor
    • Jin JS, D'Alecy LG. Central and peripheral effects of asymmetric dimethylarginine, an endogenous nitric oxide synthetase inhibitor. J Cardiovasc Pharmacol 28: 439-446, 1996.
    • (1996) J Cardiovasc Pharmacol , vol.28 , pp. 439-446
    • Jin, J.S.1    D'Alecy, L.G.2
  • 22
    • 0141645386 scopus 로고    scopus 로고
    • Common genetic variation in a basal promoter element alters DDAH2 expression in endothelial cells
    • Jones LC, Tran CT, Leiper JM, Hingorani AD, Vallance P. Common genetic variation in a basal promoter element alters DDAH2 expression in endothelial cells. Biochem Biophys Res Commun 310: 836-843, 2003.
    • (2003) Biochem Biophys Res Commun , vol.310 , pp. 836-843
    • Jones, L.C.1    Tran, C.T.2    Leiper, J.M.3    Hingorani, A.D.4    Vallance, P.5
  • 23
    • 0014940650 scopus 로고
    • Isolation and identification of N-G,N-G- and N-G,N′ -G-dimethyl-arginine, N-epsilon-mono-, di-, and trimethyllysine, and glucosylgalactosyl- and galactosyl-delta-hydroxylysine from human urine
    • Kakimoto Y, Akazawa S. Isolation and identification of N-G,N-G- and N-G,N′ -G-dimethyl-arginine, N-epsilon-mono-, di-, and trimethyllysine, and glucosylgalactosyl- and galactosyl-delta-hydroxylysine from human urine. J Biol Chem 245: 5751-5758, 1970.
    • (1970) J Biol Chem , vol.245 , pp. 5751-5758
    • Kakimoto, Y.1    Akazawa, S.2
  • 24
    • 56249115245 scopus 로고    scopus 로고
    • Asymmetric dimethylarginine: A novel marker of risk and a potential target for therapy in chronic kidney disease
    • Kielstein JT, Zoccali C. Asymmetric dimethylarginine: a novel marker of risk and a potential target for therapy in chronic kidney disease. Curr Opin Nephrol Hypertens 17: 609-615, 2008.
    • (2008) Curr Opin Nephrol Hypertens , vol.17 , pp. 609-615
    • Kielstein, J.T.1    Zoccali, C.2
  • 27
    • 0033566683 scopus 로고    scopus 로고
    • Biological significance of endogenous methylarginines that inhibit nitric oxide synthases
    • Leiper J, Vallance P. Biological significance of endogenous methylarginines that inhibit nitric oxide synthases. Cardiovasc Res 43: 542-548, 1999.
    • (1999) Cardiovasc Res , vol.43 , pp. 542-548
    • Leiper, J.1    Vallance, P.2
  • 28
    • 0033214074 scopus 로고    scopus 로고
    • Identification of two human dimethylarginine dimethylaminohydrolases with distinct tissue distributions and homology with microbial arginine deiminases
    • Leiper JM, Santa Maria J, Chubb A, MacAllister RJ, Charles IG, Whitley GS, Vallance P. Identification of two human dimethylarginine dimethylaminohydrolases with distinct tissue distributions and homology with microbial arginine deiminases. Biochem J 343: 209-214, 1999.
    • (1999) Biochem J , vol.343 , pp. 209-214
    • Leiper, J.M.1    Santa Maria, J.2    Chubb, A.3    MacAllister, R.J.4    Charles, I.G.5    Whitley, G.S.6    Vallance, P.7
  • 29
    • 42149132162 scopus 로고    scopus 로고
    • Asymmetric dimethylarginine independently predicts fatal and nonfatal myocardial infarction and stroke in women: 24-year follow-up of the population study of women in Gothenburg
    • Leong T, Zylberstein D, Graham I, Lissner L, Ward D, Fogarty J, Bengtsson C, Bjorkelund C, Thelle D. Asymmetric dimethylarginine independently predicts fatal and nonfatal myocardial infarction and stroke in women: 24-year follow-up of the population study of women in Gothenburg. Arterioscler Thromb Vasc Biol 28: 961-967, 2008.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 961-967
    • Leong, T.1    Zylberstein, D.2    Graham, I.3    Lissner, L.4    Ward, D.5    Fogarty, J.6    Bengtsson, C.7    Bjorkelund, C.8    Thelle, D.9
  • 30
    • 0037143637 scopus 로고    scopus 로고
    • Impaired nitric oxide synthase pathway in diabetes mellitus: Role of asymmetric dimethylarginine and dimethylarginine dimethylaminohydrolase
    • Lin KY, Ito A, Asagami T, Tsao PS, Adimoolam S, Kimoto M, Tsuji H, Reaven GM, Cooke JP. Impaired nitric oxide synthase pathway in diabetes mellitus: role of asymmetric dimethylarginine and dimethylarginine dimethylaminohydrolase. Circulation 106: 987-992, 2002.
    • (2002) Circulation , vol.106 , pp. 987-992
    • Lin, K.Y.1    Ito, A.2    Asagami, T.3    Tsao, P.S.4    Adimoolam, S.5    Kimoto, M.6    Tsuji, H.7    Reaven, G.M.8    Cooke, J.P.9
  • 31
    • 34547697352 scopus 로고    scopus 로고
    • Elevated plasma concentrations of the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine predict adverse events in patients undergoing noncardiac surgery
    • Maas R, Dentz L, Schwedhelm E, Thoms W, Kuss O, Hiltmeyer N, Haddad M, Kloss T, Standl T, Boger RH. Elevated plasma concentrations of the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine predict adverse events in patients undergoing noncardiac surgery. Crit Care Med 35: 1876-1881, 2007.
    • (2007) Crit Care Med , vol.35 , pp. 1876-1881
    • Maas, R.1    Dentz, L.2    Schwedhelm, E.3    Thoms, W.4    Kuss, O.5    Hiltmeyer, N.6    Haddad, M.7    Kloss, T.8    Standl, T.9    Boger, R.H.10
  • 32
    • 34147194549 scopus 로고    scopus 로고
    • Asymmetric dimethylarginine, smoking, and risk of coronary heart disease in apparently healthy men: Prospective analysis from the population-based Monitoring of Trends and Determinants in Cardiovascular Disease/Kooperative Gesundheitsforschung in der Region Augsburg study and experimental data
    • Maas R, Schulze F, Baumert J, Lowel H, Hamraz K, Schwedhelm E, Koenig W, Boger RH. Asymmetric dimethylarginine, smoking, and risk of coronary heart disease in apparently healthy men: prospective analysis from the population-based Monitoring of Trends and Determinants in Cardiovascular Disease/Kooperative Gesundheitsforschung in der Region Augsburg study and experimental data. Clin Chem 53: 693-701, 2007.
    • (2007) Clin Chem , vol.53 , pp. 693-701
    • Maas, R.1    Schulze, F.2    Baumert, J.3    Lowel, H.4    Hamraz, K.5    Schwedhelm, E.6    Koenig, W.7    Boger, R.H.8
  • 36
    • 0025883342 scopus 로고
    • Nitric oxide: Physiology, pathophysiology, and pharmacology
    • Moncada S, Palmer RM, Higgs EA. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol Rev 43: 109-142, 1991.
    • (1991) Pharmacol Rev , vol.43 , pp. 109-142
    • Moncada, S.1    Palmer, R.M.2    Higgs, E.A.3
  • 39
  • 40
    • 36849013997 scopus 로고    scopus 로고
    • Dimethylarginine dimethylaminohydrolase (DDAH): Expression, regulation, and function in the cardiovascular and renal systems
    • Palm F, Onozato ML, Luo Z, Wilcox CS. Dimethylarginine dimethylaminohydrolase (DDAH): expression, regulation, and function in the cardiovascular and renal systems. Am J Physiol Heart Circ Physiol 293: H3227-H3245, 2007.
    • (2007) Am J Physiol Heart Circ Physiol , vol.293
    • Palm, F.1    Onozato, M.L.2    Luo, Z.3    Wilcox, C.S.4
  • 41
    • 43249088598 scopus 로고    scopus 로고
    • Panichi V, Mantuano E, Paoletti S, Santi S, Manca Rizza G, Cutrupi S, Pizzini P, Spoto B, Tripepi G, Zoccali C. Effect of simvastatin on plasma asymmetric dimethylarginine concentration in patients with chronic kidney disease. J Nephrol 21: 38-44, 2008.
    • Panichi V, Mantuano E, Paoletti S, Santi S, Manca Rizza G, Cutrupi S, Pizzini P, Spoto B, Tripepi G, Zoccali C. Effect of simvastatin on plasma asymmetric dimethylarginine concentration in patients with chronic kidney disease. J Nephrol 21: 38-44, 2008.
  • 43
    • 38749102425 scopus 로고    scopus 로고
    • Effects of atorvastatin on the different phases of atherogenesis
    • Rubba P. Effects of atorvastatin on the different phases of atherogenesis. Drugs 67, Suppl 1: 17-27, 2007.
    • (2007) Drugs , vol.67 , Issue.SUPPL. 1 , pp. 17-27
    • Rubba, P.1
  • 44
    • 0032520153 scopus 로고    scopus 로고
    • Direct evidence for the importance of endothelium-derived nitric oxide in vascular remodeling
    • Rudic RD, Shesely EG, Maeda N, Smithies O, Segal SS, Sessa WC. Direct evidence for the importance of endothelium-derived nitric oxide in vascular remodeling. J Clin Invest 101: 731-736, 1998.
    • (1998) J Clin Invest , vol.101 , pp. 731-736
    • Rudic, R.D.1    Shesely, E.G.2    Maeda, N.3    Smithies, O.4    Segal, S.S.5    Sessa, W.C.6
  • 46
    • 33751104228 scopus 로고    scopus 로고
    • Transcriptional and posttranscriptional regulation of endothelial nitric oxide synthase expression
    • Searles CD. Transcriptional and posttranscriptional regulation of endothelial nitric oxide synthase expression. Am J Physiol Cell Physiol 291: C803-C816, 2006.
    • (2006) Am J Physiol Cell Physiol , vol.291
    • Searles, C.D.1
  • 49
    • 24944522337 scopus 로고    scopus 로고
    • Dimethylarginine dimethylaminohydrolase overexpression suppresses graft coronary artery disease
    • Tanaka M, Sydow K, Gunawan F, Jacobi J, Tsao PS, Robbins RC, Cooke JP. Dimethylarginine dimethylaminohydrolase overexpression suppresses graft coronary artery disease. Circulation 112: 1549-1556, 2005.
    • (2005) Circulation , vol.112 , pp. 1549-1556
    • Tanaka, M.1    Sydow, K.2    Gunawan, F.3    Jacobi, J.4    Tsao, P.S.5    Robbins, R.C.6    Cooke, J.P.7
  • 51
    • 27744463745 scopus 로고    scopus 로고
    • ADMA metabolism and clearance
    • Teerlink T. ADMA metabolism and clearance. Vasc Med 10, Suppl 1: S73-S81, 2005.
    • (2005) Vasc Med , vol.10 , Issue.SUPPL. 1
    • Teerlink, T.1
  • 52
    • 0037089509 scopus 로고    scopus 로고
    • Determination of arginine, asymmetric dimethylarginine, and symmetric dimethylarginine in human plasma and other biological samples by high-performance liquid chromatography
    • Teerlink T, Nijveldt RJ, de Jong S, van Leeuwen PA. Determination of arginine, asymmetric dimethylarginine, and symmetric dimethylarginine in human plasma and other biological samples by high-performance liquid chromatography. Anal Biochem 303: 131-137, 2002.
    • (2002) Anal Biochem , vol.303 , pp. 131-137
    • Teerlink, T.1    Nijveldt, R.J.2    de Jong, S.3    van Leeuwen, P.A.4
  • 55
    • 0034662784 scopus 로고    scopus 로고
    • Chromosomal localization, gene structure, and expression pattern of DDAH1: Comparison with DDAH2 and implications for evolutionary origins
    • Tran CT, Fox MF, Vallance P, Leiper JM. Chromosomal localization, gene structure, and expression pattern of DDAH1: comparison with DDAH2 and implications for evolutionary origins. Genomics 68: 101-105, 2000.
    • (2000) Genomics , vol.68 , pp. 101-105
    • Tran, C.T.1    Fox, M.F.2    Vallance, P.3    Leiper, J.M.4
  • 57
    • 36448934538 scopus 로고    scopus 로고
    • Macrophage infiltration, lectin-like oxidized-LDL receptor-1, and monocyte chemoattractant protein-1 are reduced by chronic HMG-CoA reductase inhibition
    • Tsuchiya A, Nagotani S, Hayashi T, Deguchi K, Sehara Y, Yamashita T, Zhang H, Lukic V, Kamiya T, Abe K. Macrophage infiltration, lectin-like oxidized-LDL receptor-1, and monocyte chemoattractant protein-1 are reduced by chronic HMG-CoA reductase inhibition. Curr Neurovasc Res 4: 268-273, 2007.
    • (2007) Curr Neurovasc Res , vol.4 , pp. 268-273
    • Tsuchiya, A.1    Nagotani, S.2    Hayashi, T.3    Deguchi, K.4    Sehara, Y.5    Yamashita, T.6    Zhang, H.7    Lukic, V.8    Kamiya, T.9    Abe, K.10
  • 58
    • 0026548912 scopus 로고
    • Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure
    • Vallance P, Leone A, Calver A, Collier J, Moncada S. Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure. Lancet 339: 572-575, 1992.
    • (1992) Lancet , vol.339 , pp. 572-575
    • Vallance, P.1    Leone, A.2    Calver, A.3    Collier, J.4    Moncada, S.5
  • 59
    • 54249118627 scopus 로고    scopus 로고
    • Relationship of asymmetric dimethylarginine with flow-mediated dilatation in subjects with newly detected severe hypercholesterolemia
    • Vladimirova-Kitova L, Deneva T, Angelova E, Nikolov F, Marinov B, Mateva N. Relationship of asymmetric dimethylarginine with flow-mediated dilatation in subjects with newly detected severe hypercholesterolemia. Clin Physiol Funct Imaging 28: 417-425, 2008.
    • (2008) Clin Physiol Funct Imaging , vol.28 , pp. 417-425
    • Vladimirova-Kitova, L.1    Deneva, T.2    Angelova, E.3    Nikolov, F.4    Marinov, B.5    Mateva, N.6
  • 63
    • 40149096841 scopus 로고    scopus 로고
    • Detrimental effect of oxidized LDL on endothelial arginine metabolism and transportation
    • Zhang WZ, Venardos K, Finch S, Kaye DM. Detrimental effect of oxidized LDL on endothelial arginine metabolism and transportation. Int J Biochem Cell Biol 40: 920-928, 2008.
    • (2008) Int J Biochem Cell Biol , vol.40 , pp. 920-928
    • Zhang, W.Z.1    Venardos, K.2    Finch, S.3    Kaye, D.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.