메뉴 건너뛰기




Volumn 10, Issue 10, 2005, Pages 411-418

Mistletoe treatment induces GM-CSF- and IL-5 production by PBMC and increases blood granulocyte- and eosinophil counts: A placebo controlled randomized study in healthy subjects

Author keywords

Eosinophils; Granulocyte macrophage colony stimulating factor; Mistletoe lectin; T helper 2 response

Indexed keywords

ANTIGEN; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 5; ISCADOR QUERCUS SPEZIAL; PLACEBO; PLANT EXTRACT; UNCLASSIFIED DRUG; VISCOTOXIN; VISCUM ALBUM EXTRACT; VISCUM ALBUM LECTIN;

EID: 27744562512     PISSN: 09492321     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (37)

References (34)
  • 4
    • 0242277975 scopus 로고    scopus 로고
    • Influence of postoperative complementatry treatment with lectin-standardized mistletoe extract on breast cancer patients. A controlled epidemiological multicentric retrolective cohort study
    • Schumacher K, Schneider B, Reich G, Stiefel T, Stoll G, Bock PP, Hanisch J, Beuth J (2003) Influence of postoperative complementatry treatment with lectin-standardized mistletoe extract on breast cancer patients. A controlled epidemiological multicentric retrolective cohort study. Anticancer Res 23: 5081-5087
    • (2003) Anticancer Res. , vol.23 , pp. 5081-5087
    • Schumacher, K.1    Schneider, B.2    Reich, G.3    Stiefel, T.4    Stoll, G.5    Bock, P.P.6    Hanisch, J.7    Beuth, J.8
  • 5
    • 0025736132 scopus 로고
    • Demonstration of specifically sensitized lymphocytes in patients treated with an aqueous mistletoe extract
    • Schultze JL, Stettin A, Berg PA (1991) Demonstration of specifically sensitized lymphocytes in patients treated with an aqueous mistletoe extract. Klin Wochenschr 69: 397-403
    • (1991) Klin. Wochenschr. , vol.69 , pp. 397-403
    • Schultze, J.L.1    Stettin, A.2    Berg, P.A.3
  • 6
    • 0025313821 scopus 로고
    • Increased secretion of TNFa, IL-1 and IL-6 by human mononuclear cells exposed to b-galactoside-specific lectin from clinically applied mistletoe extract
    • Hajto T, Hostanka K, Frei K, Rordorf C, Gabius HJ (1990) Increased secretion of TNFa, IL-1 and IL-6 by human mononuclear cells exposed to b-galactoside-specific lectin from clinically applied mistletoe extract. Cancer Res 50: 3322-3326
    • (1990) Cancer Res. , vol.50 , pp. 3322-3326
    • Hajto, T.1    Hostanka, K.2    Frei, K.3    Rordorf, C.4    Gabius, H.J.5
  • 7
    • 0024397491 scopus 로고
    • Modulatory potencies of the beta-galactoside-specific lectin from mistletoe extracts (Iscador) on the host defense system in vivo in rabbits and patients
    • Hajto T, Hostanska K, Gabius HJ (1989) Modulatory potencies of the beta-galactoside-specific lectin from mistletoe extracts (Iscador) on the host defense system in vivo in rabbits and patients. Cancer Res 49: 4803-4808
    • (1989) Cancer Res. , vol.49 , pp. 4803-4808
    • Hajto, T.1    Hostanska, K.2    Gabius, H.J.3
  • 8
    • 0037198128 scopus 로고    scopus 로고
    • In vivo-induction of antibodies to mistletoe lectin-1 and viscotoxin by exposure to aqueous mistletoe extracts: A randomised double-blinded placebo controlled phase I study in healthy individuals
    • Klein R, Classen K, Berg PA, Lüdtke R, Werner M, Huber R (2002) In vivo-induction of antibodies to mistletoe lectin-1 and viscotoxin by exposure to aqueous mistletoe extracts: a randomised double-blinded placebo controlled phase I study in healthy individuals. Eur J Med Res 7: 155-163
    • (2002) Eur. J. Med. Res. , vol.7 , pp. 155-163
    • Klein, R.1    Classen, K.2    Berg, P.A.3    Lüdtke, R.4    Werner, M.5    Huber, R.6
  • 9
    • 0032495685 scopus 로고    scopus 로고
    • Modulation of the cellular and humoral immune responses of tumor patients by mistletoe therapy
    • Stein GM, Henn W, V.Laue HB, Berg PA (1998) Modulation of the cellular and humoral immune responses of tumor patients by mistletoe therapy. Eur J Med Res 3:194-202
    • (1998) Eur. J. Med. Res. , vol.3 , pp. 194-202
    • Stein, G.M.1    Henn, W.2    V.Laue, H.B.3    Berg, P.A.4
  • 10
    • 0033040006 scopus 로고    scopus 로고
    • Thionins from Viscum album L: Influence of the viscotoxins on the activation of granulocytes
    • Stein GM, Schaller G, Pfüller U, Schietzel M, Büssing A (1999) Thionins from Viscum album L: Influence of the viscotoxins on the activation of granulocytes. Anticancer Res 19: 1037-1042
    • (1999) Anticancer Res. , vol.19 , pp. 1037-1042
    • Stein, G.M.1    Schaller, G.2    Pfüller, U.3    Schietzel, M.4    Büssing, A.5
  • 11
    • 0032936254 scopus 로고    scopus 로고
    • Toxicity of a standardized mistletoe extract in immunocompromised and healthy individuals
    • Van Wely M, Stoss M, Gorter RW (1999) Toxicity of a standardized mistletoe extract in immunocompromised and healthy individuals. Am J Ther 6/1: 37-43
    • (1999) Am. J. Ther. , vol.6 , Issue.1 , pp. 37-43
    • Van Wely, M.1    Stoss, M.2    Gorter, R.W.3
  • 12
    • 0036979452 scopus 로고    scopus 로고
    • Effects of a lectin- and a viscotoxin-rich mistletoe preparation on clinical and hematological parameters: A placebo controlled evaluation in healthy subjects
    • Huber R, Klein R, Berg PA, Lüdtke R, Werner M (2002) Effects of a lectin- and a viscotoxin-rich mistletoe preparation on clinical and hematological parameters: a placebo controlled evaluation in healthy subjects. J. Alternative Compl Med 8: 857-866
    • (2002) J. Alternative Compl. Med. , vol.8 , pp. 857-866
    • Huber, R.1    Klein, R.2    Berg, P.A.3    Lüdtke, R.4    Werner, M.5
  • 13
    • 0035965224 scopus 로고    scopus 로고
    • Effects of a mistletoe preparation with defined lectin content on chronic hepatitis C: An individually controlled cohort study
    • Huber R, Lüdtke R, Klassen M, Müller-Buscher G, Wolff-Vorbeck G, Scheer R (2001) Effects of a mistletoe preparation with defined lectin content on chronic hepatitis C: an individually controlled cohort study. Eur J Med Res 6: 399-405
    • (2001) Eur. J. Med. Res. , vol.6 , pp. 399-405
    • Huber, R.1    Lüdtke, R.2    Klassen, M.3    Müller-Buscher, G.4    Wolff-Vorbeck, G.5    Scheer, R.6
  • 14
    • 0033606187 scopus 로고    scopus 로고
    • Characterisation of immunological reactivity of patients with adverse effects during therapy with an aqueous mistletoe extract
    • Stein GM, Berg PA (1999) Characterisation of immunological reactivity of patients with adverse effects during therapy with an aqueous mistletoe extract. Eur J Med Res 4: 169-177
    • (1999) Eur. J. Med. Res. , vol.4 , pp. 169-177
    • Stein, G.M.1    Berg, P.A.2
  • 15
    • 0026643596 scopus 로고
    • Interleukin-5, eosinophils and disease
    • Sanderson CJ (1992) Interleukin-5, eosinophils and disease. Blood 79: 3101
    • (1992) Blood , vol.79 , pp. 3101
    • Sanderson, C.J.1
  • 16
    • 0035989709 scopus 로고    scopus 로고
    • Intracellular signal transduction in eosinophils and its clinical significance
    • Wong CK, Zhang J, Ip WK, Lam CW (2002) Intracellular signal transduction in eosinophils and its clinical significance. Immunopharmacol Immunotoxicol 24: 165-186
    • (2002) Immunopharmacol. Immunotoxicol. , vol.24 , pp. 165-186
    • Wong, C.K.1    Zhang, J.2    Ip, W.K.3    Lam, C.W.4
  • 17
    • 0029928417 scopus 로고    scopus 로고
    • The expanding universe of T-cell subsets: Th1, Th2 and more
    • Mosman TR, Sad S (1996) The expanding universe of T-cell subsets: Th1, Th2 and more. Immunol Today 17: 138-146
    • (1996) Immunol. Today , vol.17 , pp. 138-146
    • Mosman, T.R.1    Sad, S.2
  • 19
    • 0022974278 scopus 로고
    • Immunomodulatory effects of iscador: A Viscum album preparation
    • Hajto T (1986) Immunomodulatory effects of iscador: a Viscum album preparation. Oncology 43 Suppl 1: 51-65
    • (1986) Oncology , vol.43 , Issue.SUPPL. 1 , pp. 51-65
    • Hajto, T.1
  • 20
    • 0036635527 scopus 로고    scopus 로고
    • Granulocyte macrophage colony-stimulating factor: Current practice and novel approaches
    • Buchsel PC, Forgey A, Grape FB, Hamann SS (2002) Granulocyte macrophage colony-stimulating factor: current practice and novel approaches. Clin J Oncol Nurs 6: 198-105
    • (2002) Clin. J. Oncol. Nurs. , vol.6 , pp. 105-198
    • Buchsel, P.C.1    Forgey, A.2    Grape, F.B.3    Hamann, S.S.4
  • 21
    • 0036533489 scopus 로고    scopus 로고
    • Cytokines as a link between innate and adaptive antitumor immunity
    • Belardelli F, Ferrantini M (2002) Cytokines as a link between innate and adaptive antitumor immunity. Trend Immunol 23: 201-208
    • (2002) Trend Immunol. , vol.23 , pp. 201-208
    • Belardelli, F.1    Ferrantini, M.2
  • 22
    • 0028894133 scopus 로고
    • Comparative study on the cytotoxic effect of viscotoxin and mistletoe lectin on tumor cells in culture
    • Urech K, Schaller G, Ziska P, Giannattasio M (1995) Comparative study on the cytotoxic effect of viscotoxin and mistletoe lectin on tumor cells in culture. Phytotherapy Research 9(1): 49-55
    • (1995) Phytotherapy Research , vol.9 , Issue.1 , pp. 49-55
    • Urech, K.1    Schaller, G.2    Ziska, P.3    Giannattasio, M.4
  • 23
  • 24
    • 0141762549 scopus 로고    scopus 로고
    • Methods for the in vitro determination of an individual disposition towards TH1- or TH2-reactivity by the application of appropriate stimulatory antigens
    • Barth H, Berg PA, Klein R (2003) Methods for the in vitro determination of an individual disposition towards TH1- or TH2-reactivity by the application of appropriate stimulatory antigens. Clin Exp Immunol 134: 78-85
    • (2003) Clin. Exp. Immunol. , vol.134 , pp. 78-85
    • Barth, H.1    Berg, P.A.2    Klein, R.3
  • 25
    • 0028040372 scopus 로고
    • Mistletoe extract standardized for the galactoside-specific lectin (ML-1) induces beta-endorphin release and immunopotentiation in breast cancer patients
    • Heiny BM, Beuth J (1994) Mistletoe extract standardized for the galactoside-specific lectin (ML-1) induces beta-endorphin release and immunopotentiation in breast cancer patients. Anticancer Res 14: 1339-1342
    • (1994) Anticancer Res. , vol.14 , pp. 1339-1342
    • Heiny, B.M.1    Beuth, J.2
  • 26
    • 0029548382 scopus 로고
    • A plant lectin derived from Viscum album induces cytokine gene expression and protein production in cultures of human peripheral blood mononuclear cells
    • Hostanska K, Hajto T, Spagnoli GC, Fischer J, Lentzen H, Herrmann R (1995) A plant lectin derived from Viscum album induces cytokine gene expression and protein production in cultures of human peripheral blood mononuclear cells. Nat Immun 14: 295-304
    • (1995) Nat. Immun. , vol.14 , pp. 295-304
    • Hostanska, K.1    Hajto, T.2    Spagnoli, G.C.3    Fischer, J.4    Lentzen, H.5    Herrmann, R.6
  • 27
    • 0037017840 scopus 로고    scopus 로고
    • Influence of pathological tumour variables on long-term survival in resectable gastric cancer
    • Cuschieri A, Talbot IC, Weeden S (2002) Influence of pathological tumour variables on long-term survival in resectable gastric cancer. Br J Cancer 86: 674-679
    • (2002) Br. J. Cancer , vol.86 , pp. 674-679
    • Cuschieri, A.1    Talbot, I.C.2    Weeden, S.3
  • 28
    • 0342424368 scopus 로고    scopus 로고
    • Prognostic influence of tumor-associated eosinophilic infiltrate in colorectal carcinoma
    • Fernandez-Acenero MJ, Galindo-Gallego M, Sanz J, Aljama A (2000) Prognostic influence of tumor-associated eosinophilic infiltrate in colorectal carcinoma. Cancer 88: 1544-1548
    • (2000) Cancer , vol.88 , pp. 1544-1548
    • Fernandez-Acenero, M.J.1    Galindo-Gallego, M.2    Sanz, J.3    Aljama, A.4
  • 29
    • 0023645081 scopus 로고
    • The human hematopoietic colony-stimulating factors
    • Clark SC, Kamen R (1987) The human hematopoietic colony-stimulating factors. Science 236: 1229
    • (1987) Science , vol.236 , pp. 1229
    • Clark, S.C.1    Kamen, R.2
  • 30
    • 0037115541 scopus 로고    scopus 로고
    • Cancer immunotherapy with interleukin 12 and granulocyte-macrophage colony stimulating factor-encapsulated microspheres: Coinduction of innate and adaptive antitumor immunity and cure of disseminated disease
    • Hill HC, Conway TF, Sabel MS, Jong YS, Mathiowitz E, Bankert RB, Egilmez NK (2002) Cancer immunotherapy with interleukin 12 and granulocyte-macrophage colony stimulating factor-encapsulated microspheres: coinduction of innate and adaptive antitumor immunity and cure of disseminated disease. Cancer Res 62: 7254-7263
    • (2002) Cancer Res , vol.62 , pp. 7254-7263
    • Hill, H.C.1    Conway, T.F.2    Sabel, M.S.3    Jong, Y.S.4    Mathiowitz, E.5    Bankert, R.B.6    Egilmez, N.K.7
  • 31
    • 0036813199 scopus 로고    scopus 로고
    • GM-CSF-based cancer vaccines
    • Dranoff G (2002) GM-CSF-based cancer vaccines. Immunol Rev 188: 147-154
    • (2002) Immunol. Rev. , vol.188 , pp. 147-154
    • Dranoff, G.1
  • 32
    • 0036875802 scopus 로고    scopus 로고
    • Stimulation of the maturation of dendritic cells in vitro by a fermented mistletoe extract
    • Stein GM, Büssing A, Schietzel M (2002) Stimulation of the maturation of dendritic cells in vitro by a fermented mistletoe extract. Anticancer Res 22: 4215-4219
    • (2002) Anticancer Res. , vol.22 , pp. 4215-4219
    • Stein, G.M.1    Büssing, A.2    Schietzel, M.3
  • 33
    • 0344737847 scopus 로고    scopus 로고
    • Comparison of low-dose versus standard colony stimulating factor in patients with chemotherapy-induced febrile neutropenia
    • Burney IA, Salam A, Jat AA, Iqbal MP, Siddiqui T, Khan MA, Smego RA Jr. (2003) Comparison of low-dose versus standard colony stimulating factor in patients with chemotherapy-induced febrile neutropenia. Oncology 65: 283-284
    • (2003) Oncology , vol.65 , pp. 283-284
    • Burney, I.A.1    Salam, A.2    Jat, A.A.3    Iqbal, M.P.4    Siddiqui, T.5    Khan, M.A.6    Smego Jr., R.A.7
  • 34
    • 0036940885 scopus 로고    scopus 로고
    • Therapeutic use of granulocyte and granulocyte-macrophage colony-stimulating factors in febrile neutropenic cancer patients. A systematic review of the literature with meta-analysis
    • Berghmans T, Paesmans M., Lafitte JJ, Mascaux C., Meert AP, Jacquy C., Burniat A., Steels E., Vallot F., Sculier JP (2002) Therapeutic use of granulocyte and granulocyte-macrophage colony-stimulating factors in febrile neutropenic cancer patients. A systematic review of the literature with meta-analysis Support Care Cancer 10: 181-188
    • (2002) Support Care Cancer , vol.10 , pp. 181-188
    • Berghmans, T.1    Paesmans, M.2    Lafitte, J.J.3    Mascaux, C.4    Meert, A.P.5    Jacquy, C.6    Burniat, A.7    Steels, E.8    Vallot, F.9    Sculier, J.P.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.