Compound K, a metabolite of ginseng saponin, induces apoptosis via caspase-8-dependent pathway in HL-60 human leukemia cells

BMC Cancer

Volumn 9, Issue , 2009, Pages

  Cho, Sung Hee ^a   Chung, Kyung Sook ^a   Choi, Jung Hye ^a   Kim, Dong Hyun ^a   Lee, Kyung Tae ^a  

^a Kyung Hee University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

20 O BETA (DEXTRO GLUCOPYRANOSYL) 20 PROTOPANAXADIOL; ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 8; CASPASE 9; COMPOUND K; CYTOCHROME C; LIPOCORTIN 5; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN BID; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; UNCLASSIFIED DRUG; CASP8 PROTEIN, HUMAN; DIABLO PROTEIN, HUMAN; GINSENOSIDE; GINSENOSIDE M1; MITOCHONDRIAL PROTEIN; SAPONIN; SIGNAL PEPTIDE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CELL DEATH; CELL GROWTH; CELL STRAIN HL 60; CELL VIABILITY; CONTROLLED STUDY; DNA FRAGMENTATION; DOWN REGULATION; ENZYME ACTIVATION; ENZYME RELEASE; HUMAN; HUMAN CELL; IC 50; IMMUNOPRECIPITATION; LEUKEMIA; MITOCHONDRIAL MEMBRANE POTENTIAL; PROTEIN SYNTHESIS; WESTERN BLOTTING; BIOLOGICAL MODEL; CELL MEMBRANE POTENTIAL; CELL STRAIN U937; CHEMISTRY; DRUG EFFECT; DRUG SCREENING; GINSENG; HELA CELL; METABOLISM; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL CULTURE;

APOPTOSIS; CASPASE 8; CYTOCHROMES C; DRUG EVALUATION, PRECLINICAL; GINSENOSIDES; HELA CELLS; HL-60 CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LEUKEMIA; MEMBRANE POTENTIALS; MITOCHONDRIAL PROTEINS; MODELS, BIOLOGICAL; PANAX; SAPONINS; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED; U937 CELLS;

EID: 74549165964     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-9-149     Document Type: Article

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