Interstitial flow influences direction of tumor cell migration through competing mechanisms

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 27, 2011, Pages 11115-11120

  Polacheck, William J ^a   Charest, Joseph L ^b   Kamm, Roger D ^a  

^a Massachusetts Institute of Technology Cambridge   (United States)

^b CHARLES STARK DRAPER LABORATORY   (United States)

Author keywords

Cell mechanics; Computational model; Mechanobiology; Signaling

Indexed keywords

CHEMOKINE RECEPTOR CCR7; FOCAL ADHESION KINASE; INTEGRIN;

ARTICLE; BREAST CARCINOMA; CELL CULTURE; CELL DENSITY; CELL MIGRATION; CELL STRUCTURE; CHEMOTAXIS; HUMAN; HUMAN CELL; INTERSTITIAL FLUID; MELANOMA CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TUMOR CELL; TUMOR SEEDING;

BIOMEDICAL ENGINEERING; BREAST NEOPLASMS; CELL COUNT; CELL LINE, TUMOR; CELL MOVEMENT; CHEMOTAXIS; EXTRACELLULAR FLUID; FEMALE; FINITE ELEMENT ANALYSIS; FOCAL ADHESION KINASE 1; HUMANS; MICROFLUIDIC ANALYTICAL TECHNIQUES; MODELS, BIOLOGICAL; NEOPLASM METASTASIS; RECEPTORS, CCR7; SIGNAL TRANSDUCTION;

EID: 79960608623     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1103581108     Document Type: Article

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