Pivotal role of inosine triphosphate pyrophosphatase in maintaining genome stability and the prevention of apoptosis in human cells

PLoS ONE

Volumn 7, Issue 2, 2012, Pages

  Menezes, Miriam Rose ^a   Waisertreiger, Irina S R ^a   Lopez Bertoni, Hernando ^a   Luo, Xu ^a   Pavlov, Youri I ^a  

^a NEBRASKA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 N HYDROXYADENINE; HYDROLASE; INOSINE TRIPHOSPHATE PYROPHOSPHATASE; PURINE DERIVATIVE; UNCLASSIFIED DRUG; BCL2L1 PROTEIN, HUMAN; HYPOXANTHINE; INORGANIC PYROPHOSPHATASE; INOSINE TRIPHOSPHATASE; NUCLEOTIDE; PROTEIN BCL X;

APOPTOSIS; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DNA STRAND BREAKAGE; ENZYME ACTIVITY; GENE; GENE OVEREXPRESSION; GENETIC PREDISPOSITION; GENETIC STABILITY; HAM1 GENE; HELA CELL; HUMAN; HUMAN CELL; ITPA GENE; KNOCKOUT GENE; MUTAGENESIS; COMET ASSAY; DEGENERATIVE DISEASE; DNA REPLICATION; GENETIC POLYMORPHISM; GENETIC TRANSFECTION; GENETICS; HUMAN GENOME; METABOLISM; NEOPLASM; PHYSIOLOGY; RISK;

APOPTOSIS; BCL-X PROTEIN; COMET ASSAY; DNA DAMAGE; DNA REPLICATION; GENOME, HUMAN; HELA CELLS; HUMANS; HYPOXANTHINE; MUTAGENESIS; NEOPLASMS; NEURODEGENERATIVE DISEASES; NUCLEOTIDES; POLYMORPHISM, GENETIC; PYROPHOSPHATASES; RISK; TRANSFECTION;

EID: 84857540521     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0032313     Document Type: Article

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