NUDT16 and ITPA play a dual protective role in maintaining chromosome stability and cell growth by eliminating dIDP/IDP and dITP/ITP from nucleotide pools in mammals

Nucleic Acids Research

Volumn 38, Issue 9, 2010, Pages 2891-2903

  Abolhassani, Nona ^a   Iyama, Teruaki ^a   Tsuchimoto, Daisuke ^a   Sakumi, Kunihiko ^a   Ohno, Mizuki ^a,b   Behmanesh, Mehrdad ^a,c   Nakabeppu, Yusaku ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c TARBIAT MODARES UNIVERSITY   (Iran)

Author keywords

[No Author keywords available]

Indexed keywords

2' DEOXYINOSINE DIPHOSPHATE; 2' DEOXYINOSINE TRIPHOSPHATE; INOSINE DERIVATIVE; INOSINE DIPHOSPHATE; INOSINE TRIPHOSPHATASE; INOSINE TRIPHOSPHATE; NUCLEOTIDE; NUDIX HYDROLASE; NUDIX TYPE MOTIF 16; PHOSPHATASE; UNCLASSIFIED DRUG; 2'-DEOXYINOSINE TRIPHOSPHATE; ACID ANHYDRIDE HYDROLASE; DEOXYINOSINE DIPHOSPHATE; DRUG DERIVATIVE; INORGANIC PYROPHOSPHATASE; INOSINE DIPHOSPHATASE; NUDT16 PROTEIN, MOUSE; PURINE NUCLEOTIDE;

ANIMAL CELL; ARTICLE; CELL GROWTH; CELL IMMORTALIZATION; CHROMOSOMAL INSTABILITY; DNA STRAND BREAKAGE; EMBRYO; ENZYME ACTIVITY; ENZYME DEFICIENCY; FIBROBLAST; HYDROLYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; ANIMAL; CELL CULTURE; CELL PROLIFERATION; GENETICS; METABOLISM; MOUSE MUTANT; PHENOTYPE; PHYSIOLOGY;

MAMMALIA; MUS;

ACID ANHYDRIDE HYDROLASES; ANIMALS; CELL PROLIFERATION; CELLS, CULTURED; CHROMOSOMAL INSTABILITY; INOSINE DIPHOSPHATE; INOSINE NUCLEOTIDES; INOSINE TRIPHOSPHATE; MICE; MICE, KNOCKOUT; PHENOTYPE; PYROPHOSPHATASES;

EID: 77953276559     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkp1250     Document Type: Article

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