Incision at hypoxanthine residues in DNA by a mammalian homologue of the Escherichia coli antimutator enzyme endonuclease V

Nucleic Acids Research

Volumn 31, Issue 14, 2003, Pages 3893-3900

  Moe, Ane ^a   Ringvoll, Jeanette ^a   Nordstrand, Line M ^a   Eide, Lars ^a   Bjør, Magnar ^a   Seeberg, Erling ^a   Rognes, Torbjørn ^a   Klungland, Arne ^a  

^a UNIVERSITY OF OSLO   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; BACTERIAL ENZYME; COMPLEMENTARY DNA; DEOXYRIBONUCLEASE; DNA; DNA GLYCOSYLTRANSFERASE; ENDONUCLEASE V; ESCHERICHIA COLI PROTEIN; ESTER DERIVATIVE; HYPOXANTHINE; NUCLEOTIDE; PHOSPHORUS DERIVATIVE; SINGLE STRANDED DNA; UNCLASSIFIED DRUG; URACIL; DEOXYRIBONUCLEASE (PYRIMIDINE DIMER); MESSENGER RNA; OLIGONUCLEOTIDE; THYMINE;

ARTICLE; BACTERIAL STRAIN; CATALYSIS; CONTROLLED STUDY; DEAMINATION; DNA BINDING; DNA DETERMINATION; DNA REPAIR; DNA STRAND; ENZYME ACTIVITY; ESCHERICHIA COLI; EXCISION REPAIR; GENETIC DISORDER; IN VITRO STUDY; KNOCKOUT MOUSE; MAMMAL; MOLECULAR WEIGHT; MOUSE; MUTATOR GENE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MOTIF; SEQUENCE HOMOLOGY; AMINO ACID SEQUENCE; ANIMAL; ENZYMOLOGY; FEMALE; GENE EXPRESSION REGULATION; GENE REPRESSION; GENETIC COMPLEMENTATION; GENETICS; HUMAN; ISOLATION AND PURIFICATION; MALE; METABOLISM; MOLECULAR GENETICS; MUTATION; NORTHERN BLOTTING; SEQUENCE ALIGNMENT;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; MAMMALIA;

AMINO ACID SEQUENCE; ANIMALS; BLOTTING, NORTHERN; CONSERVED SEQUENCE; DEOXYRIBONUCLEASE (PYRIMIDINE DIMER); DNA; DNA REPAIR; ENDODEOXYRIBONUCLEASES; ESCHERICHIA COLI; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENETIC COMPLEMENTATION TEST; HUMANS; HYPOXANTHINE; MALE; MICE; MOLECULAR SEQUENCE DATA; MUTATION; OLIGONUCLEOTIDES; RNA, MESSENGER; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; SUPPRESSION, GENETIC; THYMINE; URACIL;

EID: 0242380643     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/gkg472     Document Type: Article

References (50)

1. Lindahl,T. (1993) Instability and decay of the primary structure of DNA. Nature, 362, 709-715.
2. Dulbecco,R. (1949) Reactivation of ultraviolet inactivated bacteriophage by visible light. Nature, 163, 949-950.
3. Sedgwick,B. (1983) Molecular cloning of a gwe which regulates the adaptive response to alkylating agents in Escherichia coli. Mol. Genet. Genetics, 191, 466-472.
4. Trewick,S.C., Henshaw,T.F., Hausinger,R.P., Lindahl,T. and Sedgwick,B. (2002) Oxidative demethylation by Escherichia coli AlkB directly reverts DNA base damage. Nature, 419, 174-178.
5. Falnes,P.O., Johansen,R.F. and Seeberg,E. (2002) AlkB-mediated oxidative demethylation reverses DNA damage in Escherichia coli. Nature, 419, 178-182.
6. Duncan,T., Trewick,S.C., Koivisto,P., Bates,P.A., Lindahl,T. and Sedgwick,B. (2002) Reversal of DNA alkylation damage by two human dioxygenases. Proc. Natl Acad. Sci. USA, 99, 16660-16665.
7. Aas,P.A., Otterlei,M., Falnes,P.Ø., Vågbø,C.B., Skorpen,F., Akbari,M., Sundheim,O., Bjørås,M., Slupphaug,G., Seeberg,E. and Krokan,H.E. (2003) Human and bacterial oxidative demethylases repair alkylation damage in both DNA and RNA. Nature, 421, 859-863.
8. Lindahl,T., Karran,P. and Wood,RD. (1997) DNA excision repair pathways. Curr. Opin. Genet. Dev., 7, 158-169.
9. Lindahl,T. (1974) An N-glycosidase from Escherichia coli that releases free uracil from DNA containing deaminated cytosine residues. Proc. Natl Acad. Sci. USA, 71, 3649-3653.
10. Seeberg,E., Eide,L. and Bjørås,M. (1995) The base excision repair pathway. Trends Biochem. Sci., 20, 391-397.
11. Sancar,A. and Rupp,W.D. (1983) A novel repair enzyme: UVRABC excision nuclease of Escherichia coli cuts a DNA strand on both sides of the damaged region. Cell, 33, 249-260.
12. Seeberg,E., Nissen-Meyer,J. and Strike,P. (1976) Incision of ultraviolet-irradiated DNA by extracts of E. coli requires three different gene products. Nature, 263, 524-526.
13. Schouten,K. and Weiss,B. (1999) Endonuclease V protects Escherichia coli against specific mutations caused by nitrous acid. Mutat. Res., 435, 245-254.
14. Hill-Perkins,M., Jones,M.D. and Karran,P. (1986) Site-specific mutagenesis in vivo by single methylated or deaminated purine bases. Mutat. Res., 162, 153-163.
15. Gates,F.T.,III and Linn,S. (1977) Endonuclease V of Escherichia coli. J. Biol. Chem., 252, 1647-1653.
16. Demple,B. and Linn,S. (1982) On the recognition and cleavage mechanism of Escherichia coli endodeoxyribonuclease V, a possible DNA repair enzyme. J. Biol. Chem., 257, 2848-2855.
17. Yao,M., Hatahet,Z., Melamede,R.J. and Kow,Y.W. (1994) Purification and characterization of a novel deoxyinosine-specific enzyme, deoxynosine 3′ endonuclease, from Escherichia coli. J. Biol. Chem., 269, 16260-46268.
18. Yao,M. and Kow,Y.W. (1994) Strand-specific cleavage of mismatch-containing DNA by deoxyinosine 3′endonuclease from Escherichia coli. J. Biol. Chem., 269, 31390-31396.
19. Yao,M. and Kow,Y.W. (1996) Interaction of deoxyinosine 3′endonuclease from Escherichia coli with DNA containing deoxyinosine. J. Biol. Chem., 271, 30672-30676.
20. Liu,J., He,B., Qing,H. and Kow,Y.W. (2000) A deoxymosine specific endonuclease from hyperthermophile, Archaeoglobus fulgidus: a homolog of Escherichia coli endonuclease V. Mutat. Res., 461, 169-177.
21. Rupp,W.D. (1996) DNA repair mechanisms. In Neidhardt,F.C., Curtiss,R.,III, Ingraham,J.L., Lin,E.C.C, Low,K.B., Magasanik,B., Reznikoff,W.S., Riley,M., Schaechter,M. and Umbarger,H.E. (eds), Escherichia coli and Salmonella: Cellular and Molecular Biology, 2nd Edn. ASM Press, Washington, D.C., pp. 2277-2294.
22. Glickman,B.W. and Radman,M. (1980) Escherichia coli mutator mutants deficient in methylation-instructed DNA mismatch correction. Proc. Natl Acad. Sci. USA, 77, 1063-1067.
23. Lieb,M. (1987) Bacterial genes mutL, mutS, and dcm participate in repair of mismatches at 5-methylcytosine sites. J. Bacteriol., 169, 5241-5246.
24. Kow,Y.W. (2002) Repair of deaminated bases in DNA. Free Radical Biol. Med., 33, 886-893.
25. Aravind,L., Walker,D.R. and Koonin,E.V. (1999) Conserved domains in DNA repair proteins and evolution of repair systems. Nucleic Acids Res., 27, 1223-1242.
26. Huang,J., Lu,J., Barany,F. and Cao,W. (2001) Multiple cleavage activities of endonuclease V from Thermotoga maritima: recognition and strand nicking mechanism. Biochemistry, 40, 8738-8748.
27. Thompson,J.D., Higgins,D.G. and Gibson,T.J. (1994) CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res., 22, 4673-4680.
28. Pearl,L.H. (2000) Structure and function in the uracil-DNA glycosylase superfamily. Mutat. Res., 460, 165-181.
29. Olsen,A.K., Bjørtuft,H., Wiger,R., Holme,J., Seeberg,E., Bjørås,M. and Brunborg,G. (2001) Highly efficient base excision repair (BER) in human and rat male germ cells. Nucleic Acids Res., 29, 1781-1790.
30. Niederreither,K., Harbers,M., Chambon,P. and Dolle,P. (1998) Expression of T:G mismatch-specific thymidine-DNA glycosylase and DNA methyl transferase genes during development and tumorigenesis. Oncogene, 17, 1577-1585.
31. Huang,J., Kirk,B., Favis,R., Soussi,T., Paty,P., Cao,W. and Barany,F. (2002) An endonuclease/ligase based mutation scanning method especially suited for analysis of neoplastic tissue. Oncogene, 21, 1909-1921.
32. Huang,J., Lu,J., Barany,F. and Cao,W. (2002) Mutational analysis of endonuclease V from Thermotoga maritima. Biochemistry, 41, 8342-8350.
33. Weiss,B. (2001) Endonuclease V of Escherichia coli prevents mutations from nitrosative deamination during nitrate/nitrite respiration. Mutat. Res., 461, 301-309.
34. Saparbaev,M. and Laval,J. (1994) Excision of hypoxanthine from DNA containing dIMP residues by the Escherichia coli, yeast, rat, and human alkylpurine DNA glycosylases. Proc. Natl Acad. Sci. USA, 91, 5873-5877.
35. Sidorkina,O., Saparbaev,M. and Laval,J. (1997) Effects of nitrous acid treatment on the survival and mutagenesis of Escherichia coli cells lacking base excision repair (hypoxanthine-DNA glycosylase-ALK A protein) and/or nucleotide excision repair. Mutagenesis, 12, 23-28.
36. Kumura,K., Sekiguchi,M., Steinum,A.L. and Seeberg,E. (1985) Stimulation of the UvrABC enzyme-catalyzed repair reactions by the UvrD protein (DNA helicase II). Nucleic Acids Res., 13, 1483-1492.
37. Klungland,A., Höss,M., Gunz,D., Constantiou,A., Clarkson,S.G., Doetsch,P.W., Bolton,P.H., Wood,R.D. and Lindahl,T. (1999) Base excision repair of oxidative DNA damage activated by XPG protein. Mol. Cell, 3, 33-42.
38. Liu,X. and Roy,R. (2002) Truncation of amino-terminal stimulates activity of human endonuclease III (hNTH1). J. Mol. Biol., 321, 265-276.
39. Friedberg,E.C. and Meira,L.B. (2000) Database of mouse strains carrying targeted mutations in genes affecting cellular responses to DNA damage. Version 4. Mutat. Res., 459, 243-274.
40. Engelward,B.P., Dreslin,A., Christensen,J., Huszar,D., Kurahara,C. and Samson,L. (1996) Repair-deficient 3-methyladenine DNA glycosylase homozygous mutant mouse cells have increased sensitivity to alkylation-induced chromosome damage and cell killing. EMBO J., 15, 945-952.
41. Minowa,O., Arai,T., Hirano,M., Monden,Y., Nakai,S., Fukuda,M., Itoh,M., Takano,H., Hippou,Y., Aburatani,H., Masumura,K., Nohmi,T., Nishimura,S. and Noda,T. (2000) Mmh/Ogg1 gene inactivation results in accumulation of 8-hydroxyguanine in mice. Proc. Natl Acad. Sci. USA, 97, 4156-4161.
42. Klungland,A., Rosewell,l., Hollenbach,S., Larsen,E., Daly,G., Epe,B., Seeberg,E., Lindahl,T. and Barnes,D.E. (1999) Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage. Proc. Natl Acad. Sci. USA, 96, 13300-13305.
43. Nilsen,H., Rosewell,I., Robins,P., Skjelbred,C.F., Andersen,S., Slupphaug,G., Daly,G., Krokan,H.E., Lindahl,T. and Barnes,D.E. (2000) Uracil-DNA glycosylase (UNG)-deficient mice reveal a primary role of the enzyme during DNA replication. Mol. Cell, 5, 1059-1065.
44. Takao,M., Kanno,S., Shiromoto,T., Hasegawa,R., Ide,H., Ikeda,S., Sarker,A.H., Seki,S., Xing,J.Z., Le,X.C. et al. (2002) Novel nuclear and mitochondrial glycosylases revealed by disruption of the mouse Nth1 gene encoding an endonuclease III homolog for repair of thymine glycols. EMBO J., 21, 3486-3493.
45. Haushalter,K.A., Todd Stukenberg,M.W., Kirschner,M.W. and Verdine,G.L. (1999) Identification of a new uracil-DNA glycosylase family by expression cloning using synthetic inhibitors. Curr. Biol., 9, 174-185.
46. Engelward,B.P., Weeda,G., Wyatt,M.D., BroekhofJ.L., de Wit,J., Donker,I., Allan,J.M., Gold,B., Hoeijmakers,J.H. and Samson,L.D. (1997) Base excision repair deficient mice lacking the Aag alkyladenine DNA glycosylase. Proc. Natl Acad. Sci. USA, 94, 13087-13092.
47. Hang,B., Singer.B., Margison,G.P. and Elder,R.H. (1997) Targeted deletion of alkylpurine-DNA-N-glycosylase in mice eliminates repair of 1,N6-ethenoadenine and hypoxanthine but not of 3,N4-ethenocytosine or 8-oxoguanine. Proc. Natl Acad. Sci. USA, 94, 12869-12874.
48. LePage,F., Klungland,A., Barnes,D.E., Sarasin,A. and Boiteux,S. (2000) Transcription coupled repair of 8-oxoguanine in murine cells: the Ogg1 protein is required for repair in nontranscribed sequences but not in transcribed sequences. Proc. Natl Acad. Sci. USA, 97, 8397-8402.
49. Chou,K.-M. and Cheng,Y.-C. (2002) An exonucleolytic activity of human apurinic/apyrimidinic endonuclease on 3′ mispaired DNA. Nature, 415, 655-659.
50. Constantinou,A., Chen,X.B., McGowan,C.H. and West,S.C. (2002) Holliday junction resolution in human cells: two junction endonucleases with distinct substrate specificities. EMBO J., 21, 5577-5585.