Guiding ATM to broken DNA

Science

Volumn 308, Issue 5721, 2005, Pages 510-511

  Abraham, Robert T ^a   Tibbetts, Randal S ^b  

^a BURNHAM INSTITUTE   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; DNA; GENOMIC DNA; CELL CYCLE PROTEIN; CHLOROQUINE; DNA BINDING PROTEIN; HISTONE DEACETYLASE; MRE11A PROTEIN, HUMAN; NBS1 PROTEIN, HUMAN; NUCLEAR PROTEIN; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; PROTEIN SERINE THREONINE KINASE; RAD50 PROTEIN, HUMAN; RECOMBINANT PROTEIN; SERINE; SINGLE STRANDED DNA; TUMOR SUPPRESSOR PROTEIN;

BIOCHEMISTRY;

ATAXIA TELANGIECTASIA; CARBOXY TERMINAL SEQUENCE; CELL CYCLE; DNA DAMAGE; DNA REPAIR; DNA STRAND BREAKAGE; ENZYME ACTIVITY; GENE AMPLIFICATION; GENE MUTATION; GENOMICS; HUMAN; IONIZING RADIATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SHORT SURVEY; AMINO ACID SUBSTITUTION; BIOLOGICAL MODEL; CHEMISTRY; DIMERIZATION; DRUG ANTAGONISM; ENZYME ACTIVATION; GENETICS; METABOLISM; MUTATION; NOTE; PHOSPHORYLATION; PROTEIN BINDING; SIGNAL TRANSDUCTION;

ATAXIA; ATAXIA TELANGIECTASIA;

AMINO ACID SUBSTITUTION; CELL CYCLE PROTEINS; CHLOROQUINE; DIMERIZATION; DNA; DNA DAMAGE; DNA REPAIR; DNA REPAIR ENZYMES; DNA, SINGLE-STRANDED; DNA-BINDING PROTEINS; ENZYME ACTIVATION; HISTONE DEACETYLASES; HUMANS; MODELS, BIOLOGICAL; MUTATION; NUCLEAR PROTEINS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; RECOMBINANT PROTEINS; SERINE; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEINS;

EID: 17644392463     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1112069     Document Type: Short Survey

References (11)

1. Y. Shiloh, Nat. Rev. Cancer 3, 155 (2003).
2. J.-H. Lee, T. T. Paull, Science 308, 551 (2005); published online 24 March 2005 (10.1126/science.1108297).
3. C. J. Bakkenist, M. B. Kastan, Nature 421, 499 (2003).
4. J. H. Petrini, Curr. Opin. Cell Biol. 12, 293 (2000).
5. C. J. Bakkenist, M. B. Kastan, Cell 118, 9 (2004).
6. J. Falck, J. Coates, S. P. Jackson, Nature 434, 605 (2005).
7. V. Costanzo, T. Paull, M. Gottesman, J. Gautier, PLoS Biol. 2, E110 (2004).
8. C. T. Carson et al., EMBO J. 22, 6610 (2003).
9. J. H. Lee, T. T. Paull, Science 304, 93 (2004).
10. L. Zou, S. J. Elledge, Science 300, 1542 (2003).
11. D. D'Amours, S. P. Jackson, Nat. Rev. Mol. Cell Biol. 3, 317 (2002).