-
1
-
-
0032434055
-
How and why we age
-
Hayflick L. How and why we age. Exp. Gerontol. 1998; 33: 639-53.
-
(1998)
Exp. Gerontol.
, vol.33
, pp. 639-653
-
-
Hayflick, L.1
-
2
-
-
77049308856
-
Aging: A theory based on free radical and radiation chemistry
-
Harman D. Aging: A theory based on free radical and radiation chemistry. J. Gerontol. 1956; 11: 298-300.
-
(1956)
J. Gerontol.
, vol.11
, pp. 298-300
-
-
Harman, D.1
-
3
-
-
0015383617
-
Free radical theory of aging: Dietary implications
-
Harman D. Free radical theory of aging: Dietary implications. Am. J. Clin. Nutr. 1972; 25: 839-43.
-
(1972)
Am. J. Clin. Nutr.
, vol.25
, pp. 839-843
-
-
Harman, D.1
-
4
-
-
0033369476
-
Mitochondrial oxygen radical generation and leak: Sites of production in states 4 and 3, organ specificity, and relation to aging and longevity
-
Barja G. Mitochondrial oxygen radical generation and leak: Sites of production in states 4 and 3, organ specificity, and relation to aging and longevity. J. Bioenerg. Biomembr. 1999; 31: 347-66.
-
(1999)
J. Bioenerg. Biomembr.
, vol.31
, pp. 347-366
-
-
Barja, G.1
-
5
-
-
0035872902
-
A reliable assessment of 8-oxo-2-deoxyguanosine levels in nuclear and mitochondrial DNA using the sodium iodide method to isolate DNA
-
Hamilton ML, Guo Z, Fuller CDet al.A reliable assessment of 8-oxo-2-deoxyguanosine levels in nuclear and mitochondrial DNA using the sodium iodide method to isolate DNA. Nucleic Acids Res. 2001; 29: 2117-26.
-
(2001)
Nucleic Acids Res.
, vol.29
, pp. 2117-2126
-
-
Hamilton, M.L.1
Guo, Z.2
Fuller, C.D.3
-
6
-
-
0032541401
-
The mtDNA-encoded ND6 subunit of mitochondrial NADH dehydrogenase is essential for the assembly of the membrane arm and respiratory function of the enzyme
-
Bai Y, Attardi G. The mtDNA-encoded ND6 subunit of mitochondrial NADH dehydrogenase is essential for the assembly of the membrane arm and respiratory function of the enzyme. EMBO J. 1998; 17: 4848-58.
-
(1998)
EMBO J.
, vol.17
, pp. 4848-4858
-
-
Bai, Y.1
Attardi, G.2
-
7
-
-
0023029883
-
Cytochorome b is necessary for the effective processing of core protein I and the iron-sulfur protein of complex III in the mitochondria
-
Sen K, Beattie DS. Cytochorome b is necessary for the effective processing of core protein I and the iron-sulfur protein of complex III in the mitochondria. Arch. Biochem. Biophys. 1986; 251: 239-49.
-
(1986)
Arch. Biochem. Biophys.
, vol.251
, pp. 239-249
-
-
Sen, K.1
Beattie, D.S.2
-
8
-
-
0036236939
-
The reductive hotspot hypothesis of mammalian aging: Membrane metabolism magnifies mutant mitochondrial mischief
-
de Grey ADNJ. The reductive hotspot hypothesis of mammalian aging: Membrane metabolism magnifies mutant mitochondrial mischief. Eur. J. Biochem. 2002; 269: 2003-9.
-
(2002)
Eur. J. Biochem.
, vol.269
, pp. 2003-2009
-
-
de Grey, A.D.N.J.1
-
9
-
-
0038010637
-
A hypothesis for the minimal overall structure of the mammalian plasma membrane redox system
-
de Grey ADNJ. A hypothesis for the minimal overall structure of the mammalian plasma membrane redox system. Protoplasma 2003; 221: 3-9.
-
(2003)
Protoplasma
, vol.221
, pp. 3-9
-
-
de Grey, A.D.N.J.1
-
10
-
-
0030799043
-
Low density lipoprotein oxidation and its pathobiological significance
-
Steinberg D. Low density lipoprotein oxidation and its pathobiological significance. J. Biol. Chem. 1997; 272: 20963-6.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 20963-20966
-
-
Steinberg, D.1
-
11
-
-
0027990590
-
Toxicity of mildly modified low-density lipoproteins to cultured retinal capillary endothelial cells and pericytes
-
Lyons TJ, Li W, Wells-Knecht MC, Jokl R. Toxicity of mildly modified low-density lipoproteins to cultured retinal capillary endothelial cells and pericytes. Diabetes 1994; 43: 1090-5.
-
(1994)
Diabetes
, vol.43
, pp. 1090-1095
-
-
Lyons, T.J.1
Li, W.2
Wells-Knecht, M.C.3
Jokl, R.4
-
12
-
-
0034006162
-
Ubiquitous overexpression of Cu/Zn superoxide dismutase does not extend life span in mice
-
Huang TT, Carlson EJ, Gillespie AM, Shi Y, Epstein CJ. Ubiquitous overexpression of Cu/Zn superoxide dismutase does not extend life span in mice. J. Gerontol. A Biol. Sci. Med. Sci. 2000; 55: B5-9.
-
(2000)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.55
-
-
Huang, T.T.1
Carlson, E.J.2
Gillespie, A.M.3
Shi, Y.4
Epstein, C.J.5
-
14
-
-
66149135335
-
Reversal of the mitochondrial phenotype and slow development of oxidative biomarkers of aging in long-lived Mclk1+/- mice
-
Lapointe J, Stepanyan Z, Bigras E, Hekimi S. Reversal of the mitochondrial phenotype and slow development of oxidative biomarkers of aging in long-lived Mclk1+/- mice. J. Biol. Chem. 2009; 284: 20364-74.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 20364-20374
-
-
Lapointe, J.1
Stepanyan, Z.2
Bigras, E.3
Hekimi, S.4
-
15
-
-
54449091329
-
Early mitochondrial dysfunction in long-lived Mclk1+/- mice
-
Lapointe J, Hekimi S. Early mitochondrial dysfunction in long-lived Mclk1+/- mice. J. Biol. Chem. 2008; 283: 26217-27.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 26217-26227
-
-
Lapointe, J.1
Hekimi, S.2
-
16
-
-
77952548782
-
How increased oxidative stress promotes longevity and metabolic health: The concept of mitochondrial hormesis (mitohormesis)
-
Ristow M, Zarse K. How increased oxidative stress promotes longevity and metabolic health: The concept of mitochondrial hormesis (mitohormesis). Exp. Gerontol. 2010; 45: 410-8.
-
(2010)
Exp. Gerontol.
, vol.45
, pp. 410-418
-
-
Ristow, M.1
Zarse, K.2
-
17
-
-
77953357982
-
Impaired quality control of mitochondria: Aging from a new perspective
-
Weber TA, Reichert AS. Impaired quality control of mitochondria: Aging from a new perspective. Exp. Gerontol. 2010; 45: 503-11.
-
(2010)
Exp. Gerontol.
, vol.45
, pp. 503-511
-
-
Weber, T.A.1
Reichert, A.S.2
-
18
-
-
38849156952
-
Heart mitochondria: Gates of life and death
-
Gustafsson AB, Gottlieb RA. Heart mitochondria: Gates of life and death. Cardiovasc. Res. 2008; 77: 334-43.
-
(2008)
Cardiovasc. Res.
, vol.77
, pp. 334-343
-
-
Gustafsson, A.B.1
Gottlieb, R.A.2
-
19
-
-
34948881208
-
Mitochondria: A hub of redox activities and cellular distress
-
Kakkar P, Singh BK. Mitochondria: A hub of redox activities and cellular distress. Mol. Cell. Biochem. 2007; 305: 235-53.
-
(2007)
Mol. Cell. Biochem.
, vol.305
, pp. 235-253
-
-
Kakkar, P.1
Singh, B.K.2
-
21
-
-
0034705129
-
The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases
-
Landry J, Sutton A, Tafrov ST et al. The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases. Proc. Natl Acad. Sci. USA 2000; 97: 5807-11.
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 5807-5811
-
-
Landry, J.1
Sutton, A.2
Tafrov, S.T.3
-
22
-
-
0033214237
-
The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms
-
Kaeberlein M, McVey M, Guarente L. The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms. Genes Dev. 1999; 13: 2570-80.
-
(1999)
Genes Dev.
, vol.13
, pp. 2570-2580
-
-
Kaeberlein, M.1
McVey, M.2
Guarente, L.3
-
23
-
-
0035826271
-
Increaased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
-
Tissenbaum HA, Guarente L. Increaased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans. Nature 2001; 410: 227-30.
-
(2001)
Nature
, vol.410
, pp. 227-230
-
-
Tissenbaum, H.A.1
Guarente, L.2
-
24
-
-
3943071801
-
Sirtuin activators mimic caloric restriction and delay ageing in metazoans
-
Wood JG, Rogina B, Lavu S et al. Sirtuin activators mimic caloric restriction and delay ageing in metazoans. Nature 2004; 430: 686-9.
-
(2004)
Nature
, vol.430
, pp. 686-689
-
-
Wood, J.G.1
Rogina, B.2
Lavu, S.3
-
25
-
-
33845868198
-
Sirtuin as potential targets for metabolic syndrome
-
Guarente L. Sirtuin as potential targets for metabolic syndrome. Nature 2006; 444: 868-74.
-
(2006)
Nature
, vol.444
, pp. 868-874
-
-
Guarente, L.1
-
26
-
-
0347128279
-
Calorie restriction extends yeast life span by lowering the level of NADH
-
Lin SJ, Ford E, Haigis M, Liszt G, Guarente L. Calorie restriction extends yeast life span by lowering the level of NADH. Genes Dev. 2004; 18: 12-6.
-
(2004)
Genes Dev.
, vol.18
, pp. 12-16
-
-
Lin, S.J.1
Ford, E.2
Haigis, M.3
Liszt, G.4
Guarente, L.5
-
27
-
-
3142740860
-
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
-
Cohen HY, Miller C, Bitterman KG et al. Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase. Science 2004; 305: 390-2.
-
(2004)
Science
, vol.305
, pp. 390-392
-
-
Cohen, H.Y.1
Miller, C.2
Bitterman, K.G.3
-
28
-
-
1542373685
-
Transcriptional regulatory circuits controlling mitochondrial biogenesis and function
-
Kelly DP, Scarpulla RC. Transcriptional regulatory circuits controlling mitochondrial biogenesis and function. Gene Dev. 2004; 18: 357-68.
-
(2004)
Gene Dev.
, vol.18
, pp. 357-368
-
-
Kelly, D.P.1
Scarpulla, R.C.2
-
29
-
-
5344247243
-
PGC-1alpha: Turbocharging mitochondria
-
Houten SM, Auwerx J. PGC-1alpha: Turbocharging mitochondria. Cell 2004; 119: 5-7.
-
(2004)
Cell
, vol.119
, pp. 5-7
-
-
Houten, S.M.1
Auwerx, J.2
-
30
-
-
68149137896
-
Implications of mitochondrial DNA mutations and mitochondrial dysfunction in tumorigenesis
-
Lu J, Sharma LK, Bai Y. Implications of mitochondrial DNA mutations and mitochondrial dysfunction in tumorigenesis. Cell Res. 2009; 19: 802-15.
-
(2009)
Cell Res.
, vol.19
, pp. 802-815
-
-
Lu, J.1
Sharma, L.K.2
Bai, Y.3
-
31
-
-
0030761388
-
Dihydroorotatubiquinone oxidoreductase links mitochondria in the biosynthesis of pyrimidine nucleotides
-
Loffler M, Jockel J, Schuster G, Becker C. Dihydroorotatubiquinone oxidoreductase links mitochondria in the biosynthesis of pyrimidine nucleotides. Mol. Cell. Biochem. 1997; 174: 125-9.
-
(1997)
Mol. Cell. Biochem.
, vol.174
, pp. 125-129
-
-
Loffler, M.1
Jockel, J.2
Schuster, G.3
Becker, C.4
-
32
-
-
0028143584
-
Physiological concentrations of purines and pyrimidines
-
Traut TW. Physiological concentrations of purines and pyrimidines. Mol. Cell. Biochem. 1994; 140: 1-22.
-
(1994)
Mol. Cell. Biochem.
, vol.140
, pp. 1-22
-
-
Traut, T.W.1
-
33
-
-
0024505072
-
The molecular basis of mutations induced by deoxyribonucleoside triphosphate pool imbalances in mammalian cells
-
Meuth M. The molecular basis of mutations induced by deoxyribonucleoside triphosphate pool imbalances in mammalian cells. Exp. Cell Res. 1989; 181: 305-16.
-
(1989)
Exp. Cell Res.
, vol.181
, pp. 305-316
-
-
Meuth, M.1
-
35
-
-
0026093495
-
An overview of the relationship between oxidative stress and chemical carcinogenesis
-
Trush MA, Kensler TW. An overview of the relationship between oxidative stress and chemical carcinogenesis. Free Radic. Biol. Med. 1991; 10: 201-9.
-
(1991)
Free Radic. Biol. Med.
, vol.10
, pp. 201-209
-
-
Trush, M.A.1
Kensler, T.W.2
-
37
-
-
33644877068
-
Nitric oxide and oxidative stress in cardiovascular aging
-
online). Available from
-
Raju SV, Barouch LA, Hare JM. Nitric oxide and oxidative stress in cardiovascular aging. Sci. Aging Knowledge Environ. 2005; 2005 (online). Available from:.
-
(2005)
Sci. Aging Knowledge Environ.
, vol.2005
-
-
Raju, S.V.1
Barouch, L.A.2
Hare, J.M.3
-
38
-
-
80051541139
-
Regulatory role of mitochondria in oxidative stress and atherosclerosis
-
Chang J, Kou S, Lin W, Liu C. Regulatory role of mitochondria in oxidative stress and atherosclerosis. World J. Cardiol. 2010; 2: 150-9.
-
(2010)
World J. Cardiol.
, vol.2
, pp. 150-159
-
-
Chang, J.1
Kou, S.2
Lin, W.3
Liu, C.4
-
39
-
-
4544235673
-
Calcium, ATP and ROS: A mitochondrial love-hate triangle
-
Brookes PS, Yoon Y, Robotham L, Anders MW, Sheu S. Calcium, ATP and ROS: A mitochondrial love-hate triangle. Am. J. Physiol. Cell Physiol. 2004; 287: 817-33.
-
(2004)
Am. J. Physiol. Cell Physiol.
, vol.287
, pp. 817-833
-
-
Brookes, P.S.1
Yoon, Y.2
Robotham, L.3
Anders, M.W.4
Sheu, S.5
-
40
-
-
78249284625
-
A free radical-generating system regulates APP metabolism/processing
-
Recuero M, Munoz T, Aldudo J, Subias M, Bullido MJ, Valdivieso F. A free radical-generating system regulates APP metabolism/processing. FEBS Lett. 2010; 584: 4611-8.
-
(2010)
FEBS Lett.
, vol.584
, pp. 4611-4618
-
-
Recuero, M.1
Munoz, T.2
Aldudo, J.3
Subias, M.4
Bullido, M.J.5
Valdivieso, F.6
-
41
-
-
33646948530
-
Parkinson's disease brain mitochondrial complex I has oxidatively damaged subunits and is functionally impaired and misassembled
-
Keeney PM, Xie J, Capaldi RA, Bennett JP Jr. Parkinson's disease brain mitochondrial complex I has oxidatively damaged subunits and is functionally impaired and misassembled. J. Neurosci. 2006; 26: 5256-64.
-
(2006)
J. Neurosci.
, vol.26
, pp. 5256-5264
-
-
Keeney, P.M.1
Xie, J.2
Capaldi, R.A.3
Bennett Jr., J.P.4
-
43
-
-
0035500510
-
Amyloid-beta: An antioxidant that becomes a prooxidant and critically contributes to Alzheimer's diseases
-
Kontush A. Amyloid-beta: An antioxidant that becomes a prooxidant and critically contributes to Alzheimer's diseases. Free Radic. Biol. Med. 2001; 31: 1120-31.
-
(2001)
Free Radic. Biol. Med.
, vol.31
, pp. 1120-1131
-
-
Kontush, A.1
-
44
-
-
70449411818
-
Oxidatively modified, mitochondria-relevant brain proteins in subjects with Alzheimer disease and mild cognitive impairment
-
Sultana R, Butterfield DA. Oxidatively modified, mitochondria-relevant brain proteins in subjects with Alzheimer disease and mild cognitive impairment. J. Bioenerg. Biomembr. 2009; 41: 441-6.
-
(2009)
J. Bioenerg. Biomembr.
, vol.41
, pp. 441-446
-
-
Sultana, R.1
Butterfield, D.A.2
-
45
-
-
0020685951
-
Decreased pyruvate dehydrogenase complex activity in Huntington and Alzheimer brain
-
Sorbi S, Bird ED, Blass JP. Decreased pyruvate dehydrogenase complex activity in Huntington and Alzheimer brain. Ann. Neurol. 1983; 13: 72-8.
-
(1983)
Ann. Neurol.
, vol.13
, pp. 72-78
-
-
Sorbi, S.1
Bird, E.D.2
Blass, J.P.3
-
46
-
-
0026718966
-
Brain cytochrome oxidase in Alzheimer's disease
-
Kish SJ, Bergeron C, Rajput A et al. Brain cytochrome oxidase in Alzheimer's disease. J. Neurochem. 1992; 59: 776-9.
-
(1992)
J. Neurochem.
, vol.59
, pp. 776-779
-
-
Kish, S.J.1
Bergeron, C.2
Rajput, A.3
-
47
-
-
36248988467
-
Insights into amyloid-beta-induced mitochondrial dysfunction in Alzheimer disease
-
Wang X, Su B, Perry G, Smith MA, Zhu X. Insights into amyloid-beta-induced mitochondrial dysfunction in Alzheimer disease. Free Radic. Biol. Med. 2007; 43: 1569-73.
-
(2007)
Free Radic. Biol. Med.
, vol.43
, pp. 1569-1573
-
-
Wang, X.1
Su, B.2
Perry, G.3
Smith, M.A.4
Zhu, X.5
-
48
-
-
33750594065
-
Genetics of Parkinson's disease and parkinsonism
-
Hardy J, Cai H, Cookson MR, Gwinn-Hardy K, Singleton A. Genetics of Parkinson's disease and parkinsonism. Ann. Neurol. 2006; 60: 389-98.
-
(2006)
Ann. Neurol.
, vol.60
, pp. 389-398
-
-
Hardy, J.1
Cai, H.2
Cookson, M.R.3
Gwinn-Hardy, K.4
Singleton, A.5
-
49
-
-
0025254401
-
Mitochondrial complex I deficiency in Parkinson's disease
-
Schapira AH, Cooper JM, Dexter D, Clark JB, Jenner P, Marsden CD. Mitochondrial complex I deficiency in Parkinson's disease. J. Neurochem. 1990; 54: 823-7.
-
(1990)
J. Neurochem.
, vol.54
, pp. 823-827
-
-
Schapira, A.H.1
Cooper, J.M.2
Dexter, D.3
Clark, J.B.4
Jenner, P.5
Marsden, C.D.6
-
50
-
-
0035834360
-
Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct
-
Conway KA, Rochet JC, Bieganski RM, Lansbury PT Jr. Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct. Science 2001; 294: 1346-9.
-
(2001)
Science
, vol.294
, pp. 1346-1349
-
-
Conway, K.A.1
Rochet, J.C.2
Bieganski, R.M.3
Lansbury Jr., P.T.4
-
51
-
-
44049099669
-
Mitochondrial import and accumulation of alpha-synuclein impair complex I in human dopamineric neuronal cultures and Parkinson disase brain
-
Devi L, Raghavendran V, Prabhu BM, Avadhani NG, Anadatheerthavarada HK. Mitochondrial import and accumulation of alpha-synuclein impair complex I in human dopamineric neuronal cultures and Parkinson disase brain. J. Biol. Chem. 2008; 283: 9089-100.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 9089-9100
-
-
Devi, L.1
Raghavendran, V.2
Prabhu, B.M.3
Avadhani, N.G.4
Anadatheerthavarada, H.K.5
-
52
-
-
0036415838
-
Alpha-synuclein, especially the Parkinson's disease-associated mutants, forms pore-like annular and tubular protofibrils
-
Lashuel HA, Petre BM, Wall J et al. Alpha-synuclein, especially the Parkinson's disease-associated mutants, forms pore-like annular and tubular protofibrils. J. Mol. Biol. 2002; 322: 1089-102.
-
(2002)
J. Mol. Biol.
, vol.322
, pp. 1089-1102
-
-
Lashuel, H.A.1
Petre, B.M.2
Wall, J.3
-
53
-
-
29644434199
-
Endoplasmic reticulum stress and mitochondrial cell death pathways mediate A53T mutant alpha-synuclein-induced toxicity
-
Smith WW, Jiang H, Pei Z et al. Endoplasmic reticulum stress and mitochondrial cell death pathways mediate A53T mutant alpha-synuclein-induced toxicity. Hum. Mol. Genet. 2005; 14: 3801-11.
-
(2005)
Hum. Mol. Genet.
, vol.14
, pp. 3801-3811
-
-
Smith, W.W.1
Jiang, H.2
Pei, Z.3
-
54
-
-
0025362466
-
Evaluation of vitamin A toxicity
-
Hathcock JN, Hattan DG, Jenkins MY, McDonald JT, Sundaresan PR, Wilkening VL. Evaluation of vitamin A toxicity. Am. J. Clin. Nutr. 1990; 52: 183-202.
-
(1990)
Am. J. Clin. Nutr.
, vol.52
, pp. 183-202
-
-
Hathcock, J.N.1
Hattan, D.G.2
Jenkins, M.Y.3
McDonald, J.T.4
Sundaresan, P.R.5
Wilkening, V.L.6
-
55
-
-
23244458906
-
The exicitoprotective effect of N-methyl-d-aspartate receptors is mediated by a brain-derived neurotrophic factor autocrine loop in cultured hippocampal neurons
-
Jian X, Tian F, Mearow K, Okagaki P, Lipsky RH, Marini AM. The exicitoprotective effect of N-methyl-d-aspartate receptors is mediated by a brain-derived neurotrophic factor autocrine loop in cultured hippocampal neurons. J. Neurochem. 2005; 94: 713-22.
-
(2005)
J. Neurochem.
, vol.94
, pp. 713-722
-
-
Jian, X.1
Tian, F.2
Mearow, K.3
Okagaki, P.4
Lipsky, R.H.5
Marini, A.M.6
-
56
-
-
31844439407
-
Sublethal mitochondrial stress with an attendant stoichiometric augmentation of reactive oxygen species may precipitate many of the beneficial alterations in cellular physiology produced by caloric restriction, intermittent fasting, exercise and dietary phytonutrients. 'Mitohormesis' for health and vitality
-
Tapia PC. Sublethal mitochondrial stress with an attendant stoichiometric augmentation of reactive oxygen species may precipitate many of the beneficial alterations in cellular physiology produced by caloric restriction, intermittent fasting, exercise and dietary phytonutrients. 'Mitohormesis' for health and vitality. Med. Hypotheses 2006; 66: 832-43.
-
(2006)
Med. Hypotheses
, vol.66
, pp. 832-843
-
-
Tapia, P.C.1
-
57
-
-
77952543118
-
Mitochondrial redox metabolism: Aging, longevity and dietary effects
-
Page MM, Robb EL, Salway KD, Stuart JA. Mitochondrial redox metabolism: Aging, longevity and dietary effects. Mech. Ageing Dev. 2010; 131: 242-52.
-
(2010)
Mech. Ageing Dev.
, vol.131
, pp. 242-252
-
-
Page, M.M.1
Robb, E.L.2
Salway, K.D.3
Stuart, J.A.4
-
58
-
-
41549135942
-
FoxO transcription factors in the maintenance of cellular homeostasis during aging
-
Salih DA, Brunet A. FoxO transcription factors in the maintenance of cellular homeostasis during aging. Curr. Opin. Cell Biol. 2008; 20: 126-36.
-
(2008)
Curr. Opin. Cell Biol.
, vol.20
, pp. 126-136
-
-
Salih, D.A.1
Brunet, A.2
-
59
-
-
78649635403
-
Nrf2, a guardian of healthspan and gatekeeper of species longevity
-
Lewis KN, Mele J, Hayes JD, Buffenstein R. Nrf2, a guardian of healthspan and gatekeeper of species longevity. Integr. Comp. Biol. 2010; 50: 829-43.
-
(2010)
Integr. Comp. Biol.
, vol.50
, pp. 829-843
-
-
Lewis, K.N.1
Mele, J.2
Hayes, J.D.3
Buffenstein, R.4
-
60
-
-
79951787452
-
Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB
-
Mair W, Morantte I, Rodrigues AP et al. Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB. Nature 2011; 470: 404-8.
-
(2011)
Nature
, vol.470
, pp. 404-408
-
-
Mair, W.1
Morantte, I.2
Rodrigues, A.P.3
-
63
-
-
33750909999
-
Reactive oxygen species-induced activation of the MAP kinase signaling pathways
-
McCubrey JA, Lahair MM, Franklin RA. Reactive oxygen species-induced activation of the MAP kinase signaling pathways. Antioxid. Redox Signal. 2006; 8: 1775-89.
-
(2006)
Antioxid. Redox Signal.
, vol.8
, pp. 1775-1789
-
-
McCubrey, J.A.1
Lahair, M.M.2
Franklin, R.A.3
-
64
-
-
0142043984
-
Redox signaling and the MAP kinase pathways
-
Torres M, Forman HJ. Redox signaling and the MAP kinase pathways. Biofactors 2003; 17: 287-96.
-
(2003)
Biofactors
, vol.17
, pp. 287-296
-
-
Torres, M.1
Forman, H.J.2
-
65
-
-
0037032817
-
Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases
-
Johnson GL, Lapadat R. Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science 2002; 298: 1911-2.
-
(2002)
Science
, vol.298
, pp. 1911-1912
-
-
Johnson, G.L.1
Lapadat, R.2
-
66
-
-
0037086678
-
Activation of c-Jun N-terminal kinase promotes survival of cardiac myocytes after oxidative stress
-
Dougherty CJ, Kubasiak LA, Prentice H, Andreka P, Bishopric NH, Webster KA. Activation of c-Jun N-terminal kinase promotes survival of cardiac myocytes after oxidative stress. Biochem. J. 2002; 362: 561-71.
-
(2002)
Biochem. J.
, vol.362
, pp. 561-571
-
-
Dougherty, C.J.1
Kubasiak, L.A.2
Prentice, H.3
Andreka, P.4
Bishopric, N.H.5
Webster, K.A.6
-
67
-
-
21444439970
-
Phosphorylation of c-Fos by members of the p38 MAPK family. Role in the AP-1 response to UV light
-
Tanos T, Marinissen MJ, Leskow FC et al. Phosphorylation of c-Fos by members of the p38 MAPK family. Role in the AP-1 response to UV light. J. Biol. Chem. 2005; 280: 18842-52.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 18842-18852
-
-
Tanos, T.1
Marinissen, M.J.2
Leskow, F.C.3
-
68
-
-
40049088820
-
The Nrf2-Keap1 defence pathway: Role in protection against drug-induced toxicity
-
Copple IM, Goldring CE, Kitteringham NR, Park BK. The Nrf2-Keap1 defence pathway: Role in protection against drug-induced toxicity. Toxicology 2008; 246: 24-33.
-
(2008)
Toxicology
, vol.246
, pp. 24-33
-
-
Copple, I.M.1
Goldring, C.E.2
Kitteringham, N.R.3
Park, B.K.4
-
69
-
-
33748358379
-
Mechanism of action of isothiocyanates: The induction of ARE-regulated genes is associated with activation of ERK and JNK and the phosphorylation and nuclear translocation of Nrf2
-
Xu C, Yuan X, Pan Z et al. Mechanism of action of isothiocyanates: The induction of ARE-regulated genes is associated with activation of ERK and JNK and the phosphorylation and nuclear translocation of Nrf2. Mol. Cancer Ther. 2006; 5: 1918-26.
-
(2006)
Mol. Cancer Ther.
, vol.5
, pp. 1918-1926
-
-
Xu, C.1
Yuan, X.2
Pan, Z.3
-
70
-
-
67649402187
-
The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress
-
Nguyen T, Nioi P, Pickett CB. The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress. J. Biol. Chem. 2009; 284: 13291-5.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 13291-13295
-
-
Nguyen, T.1
Nioi, P.2
Pickett, C.B.3
-
71
-
-
62249096975
-
Glutathione dysregulation and the etiology and progression of human diseases
-
Ballatori N, Krance SM, Notenboom S, Shi S, Tieu K, Hammond CL. Glutathione dysregulation and the etiology and progression of human diseases. Biol. Chem. 2009; 390: 191-214.
-
(2009)
Biol. Chem.
, vol.390
, pp. 191-214
-
-
Ballatori, N.1
Krance, S.M.2
Notenboom, S.3
Shi, S.4
Tieu, K.5
Hammond, C.L.6
-
72
-
-
12344305246
-
Glutathione metabolism in long-living Ames dwarf mice
-
Brown-Borg HM, Rakoczy SG. Glutathione metabolism in long-living Ames dwarf mice. Exp. Gerontol. 2005; 40: 115-20.
-
(2005)
Exp. Gerontol.
, vol.40
, pp. 115-120
-
-
Brown-Borg, H.M.1
Rakoczy, S.G.2
-
73
-
-
3542995049
-
Stress-inducible responses and heat shock proteins: New pharmacologic targets for cytoprotection
-
Morimoto RI, Santoro MG. Stress-inducible responses and heat shock proteins: New pharmacologic targets for cytoprotection. Nat. Biotechnol. 1998; 16: 833-8.
-
(1998)
Nat. Biotechnol.
, vol.16
, pp. 833-838
-
-
Morimoto, R.I.1
Santoro, M.G.2
-
74
-
-
0031031148
-
Nitric oxide protects cultured rat hepatocytes from tumor necrosis factor-alpha-induced apoptosis by inducing heat shock protein 70 expression
-
Kim YM, de Vera ME, Watkins SC, Billiar TR. Nitric oxide protects cultured rat hepatocytes from tumor necrosis factor-alpha-induced apoptosis by inducing heat shock protein 70 expression. J. Biol. Chem. 1997; 272: 1402-11.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 1402-1411
-
-
Kim, Y.M.1
de Vera, M.E.2
Watkins, S.C.3
Billiar, T.R.4
-
75
-
-
0031962486
-
Small stress proteins: Chaperones that act as regulators of intracellular redox state and programmed cell death
-
Arrigo AP. Small stress proteins: Chaperones that act as regulators of intracellular redox state and programmed cell death. Biol. Chem. 1998; 379: 19-26.
-
(1998)
Biol. Chem.
, vol.379
, pp. 19-26
-
-
Arrigo, A.P.1
-
76
-
-
0345410965
-
Mammalian small stress proteins protect against oxidative stress through their ability to increase glucose-6-phosphate dehdrogenase activity and by maintaining optimal cellular detoxifying machinery
-
Preville X, Salvemini F, Giraud S et al. Mammalian small stress proteins protect against oxidative stress through their ability to increase glucose-6-phosphate dehdrogenase activity and by maintaining optimal cellular detoxifying machinery. Exp. Cell Res. 1999; 247: 61-78.
-
(1999)
Exp. Cell Res.
, vol.247
, pp. 61-78
-
-
Preville, X.1
Salvemini, F.2
Giraud, S.3
-
77
-
-
34447316414
-
Trends in oxidative aging theories
-
Muller FL, Lustgarten MS, Jang Y, Richardson A, Van Remmen H. Trends in oxidative aging theories. Free Radic. Biol. Med. 2007; 43: 477-503.
-
(2007)
Free Radic. Biol. Med.
, vol.43
, pp. 477-503
-
-
Muller, F.L.1
Lustgarten, M.S.2
Jang, Y.3
Richardson, A.4
Van Remmen, H.5
-
78
-
-
25844494542
-
Sick chaperones, cellular stress, and disease
-
Macario AJ, Conway de Macario E. Sick chaperones, cellular stress, and disease. N. Engl. J. Med. 2005; 353: 1489-501.
-
(2005)
N. Engl. J. Med.
, vol.353
, pp. 1489-1501
-
-
Macario, A.J.1
Conway de Macario, E.2
-
79
-
-
57749195944
-
Insulin exhibits short-term anti-inflammatory but long-term proinflammatory effects in vitro
-
Iwasaki Y, Nishiyama M, Tagucchi T et al. Insulin exhibits short-term anti-inflammatory but long-term proinflammatory effects in vitro. Mol. Cell. Endocrinol. 2009; 298: 25-32.
-
(2009)
Mol. Cell. Endocrinol.
, vol.298
, pp. 25-32
-
-
Iwasaki, Y.1
Nishiyama, M.2
Tagucchi, T.3
-
80
-
-
40949123149
-
Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging
-
Salminen A, Huuskonen J, Ojala J, Kauppinen A, Kaarniranta K, Suuronen T. Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging. Ageing Res. Rev. 2008; 7: 83-105.
-
(2008)
Ageing Res. Rev.
, vol.7
, pp. 83-105
-
-
Salminen, A.1
Huuskonen, J.2
Ojala, J.3
Kauppinen, A.4
Kaarniranta, K.5
Suuronen, T.6
-
81
-
-
65549139675
-
Regulation of the aging process by autophagy
-
Salminen A, Kaarniranta K. Regulation of the aging process by autophagy. Trends Mol. Med. 2009; 15: 217-24.
-
(2009)
Trends Mol. Med.
, vol.15
, pp. 217-224
-
-
Salminen, A.1
Kaarniranta, K.2
-
82
-
-
74449090245
-
Insulin/IGF-1 paradox of aging: Regulation via AKT/IKK/NF-κB signaling
-
Salminen A, Kaarniranta K. Insulin/IGF-1 paradox of aging: Regulation via AKT/IKK/NF-κB signaling. Cell. Signal. 2010; 22: 573-7.
-
(2010)
Cell. Signal.
, vol.22
, pp. 573-577
-
-
Salminen, A.1
Kaarniranta, K.2
-
83
-
-
79951912532
-
Four faces of cellular senescence
-
Rodier F, Campisi J. Four faces of cellular senescence. J. Cell Biol. 2011; 192: 547-56.
-
(2011)
J. Cell Biol.
, vol.192
, pp. 547-556
-
-
Rodier, F.1
Campisi, J.2
-
84
-
-
43049084732
-
2+-induced mitochondrial permeability transition and mitochondrial membrane potential in H9c2 cardiomyocytes
-
2+-induced mitochondrial permeability transition and mitochondrial membrane potential in H9c2 cardiomyocytes. Life Sci. 2008; 82: 1092-101.
-
(2008)
Life Sci.
, vol.82
, pp. 1092-1101
-
-
Chiu, P.Y.1
Luk, K.F.2
Leung, H.Y.3
Ng, K.M.4
Ko, K.M.5
-
85
-
-
33645047393
-
Biochemical basis of the 'Qi-invigorating' action of Schisandra berry (Wu-Wei-Zi) in Chinese medicine
-
Ko KM, Chiu PY. Biochemical basis of the 'Qi-invigorating' action of Schisandra berry (Wu-Wei-Zi) in Chinese medicine. Am. J. Chin. Med. 2006; 34: 171-6.
-
(2006)
Am. J. Chin. Med.
, vol.34
, pp. 171-176
-
-
Ko, K.M.1
Chiu, P.Y.2
-
86
-
-
33747319849
-
Chronic schisandrin B treatment improves mitochondrial antioxidant status and tissue heat shock protein production in various tissues of young adult and middle-aged rats
-
Chiu PY, Leung HY, Poon MK, Ko KM. Chronic schisandrin B treatment improves mitochondrial antioxidant status and tissue heat shock protein production in various tissues of young adult and middle-aged rats. Biogerontology 2006; 7: 199-210.
-
(2006)
Biogerontology
, vol.7
, pp. 199-210
-
-
Chiu, P.Y.1
Leung, H.Y.2
Poon, M.K.3
Ko, K.M.4
-
87
-
-
33744815331
-
Effects of schisandrin B enantiomers on cellular glutathione and menadione toxicity in AML12 hepatocytes
-
Chiu PY, Leung HY, Poon MK, Mak DH, Ko KM. Effects of schisandrin B enantiomers on cellular glutathione and menadione toxicity in AML12 hepatocytes. Pharmacology 2006; 77: 63-70.
-
(2006)
Pharmacology
, vol.77
, pp. 63-70
-
-
Chiu, P.Y.1
Leung, H.Y.2
Poon, M.K.3
Mak, D.H.4
Ko, K.M.5
-
88
-
-
4644289319
-
Down-modulation of heat shock protein 70 and up-modulation of caspase-3 during schisandrin B-induced apoptosis in human hepatoma SMMC-7721 cells
-
Wu YF, Cao MF, Gao YP et al. Down-modulation of heat shock protein 70 and up-modulation of caspase-3 during schisandrin B-induced apoptosis in human hepatoma SMMC-7721 cells. World J. Gastroenterol. 2004; 10: 2944-8.
-
(2004)
World J. Gastroenterol.
, vol.10
, pp. 2944-2948
-
-
Wu, Y.F.1
Cao, M.F.2
Gao, Y.P.3
-
90
-
-
0036715310
-
Schisandrin B protects against tert-butylhydroperoxide induced cerebral toxicity by enhancing glutathione antioxidant status in mouse brain
-
Ko KM, Lam BY. Schisandrin B protects against tert-butylhydroperoxide induced cerebral toxicity by enhancing glutathione antioxidant status in mouse brain. Mol. Cell. Biochem. 2002; 238: 181-6.
-
(2002)
Mol. Cell. Biochem.
, vol.238
, pp. 181-186
-
-
Ko, K.M.1
Lam, B.Y.2
-
91
-
-
76449098446
-
Long-term schisandrin B treatment mitigates age-related impairments in mitochondrial antioxidant status and functional ability in various tissues, and improves the survival of aging C57BL/6J mice
-
Ko KM, Chen N, Leung HY, Leong EP, Poon MK, Chiu PY. Long-term schisandrin B treatment mitigates age-related impairments in mitochondrial antioxidant status and functional ability in various tissues, and improves the survival of aging C57BL/6J mice. Biofactors 2008; 34: 331-42.
-
(2008)
Biofactors
, vol.34
, pp. 331-342
-
-
Ko, K.M.1
Chen, N.2
Leung, H.Y.3
Leong, E.P.4
Poon, M.K.5
Chiu, P.Y.6
-
92
-
-
46449093978
-
Schisandrin B enhances cerebral mitochondrial antioxidant status and structural integrity, and protects against cerebral ischemia/reperfusion injury in rats
-
Chen N, Chiu PY, Ko KM. Schisandrin B enhances cerebral mitochondrial antioxidant status and structural integrity, and protects against cerebral ischemia/reperfusion injury in rats. Biol. Pharm. Bull. 2008; 31: 1387-91.
-
(2008)
Biol. Pharm. Bull.
, vol.31
, pp. 1387-1391
-
-
Chen, N.1
Chiu, P.Y.2
Ko, K.M.3
-
93
-
-
0347286640
-
Time-dependent enhancement in mitochondrial glutathione status and ATP generation capacity by schisandrin B treatment decreases the susceptibility of rat hearts to ischemia-reperfusion injury
-
Chiu PY, Ko KM. Time-dependent enhancement in mitochondrial glutathione status and ATP generation capacity by schisandrin B treatment decreases the susceptibility of rat hearts to ischemia-reperfusion injury. Biofactors 2003; 19: 43-51.
-
(2003)
Biofactors
, vol.19
, pp. 43-51
-
-
Chiu, P.Y.1
Ko, K.M.2
-
94
-
-
41849109537
-
Schisandrin B enhances renal mitochondrial antioxidant status, functional and structural integrity, and protects against gentamicin-induced nephrotoxicity in rats
-
Chiu PY, Leung HY, Ko KM. Schisandrin B enhances renal mitochondrial antioxidant status, functional and structural integrity, and protects against gentamicin-induced nephrotoxicity in rats. Biol. Pharm. Bull. 2008; 31: 602-5.
-
(2008)
Biol. Pharm. Bull.
, vol.31
, pp. 602-605
-
-
Chiu, P.Y.1
Leung, H.Y.2
Ko, K.M.3
-
95
-
-
0142011656
-
Hepatoprotective mechanism of schisandrin B. Role of mitochondrial glutathione antioxidant status and heat shock proteins
-
Chiu PY, Tang MH, Mak DH, Poon MK, Ko KM. Hepatoprotective mechanism of schisandrin B. Role of mitochondrial glutathione antioxidant status and heat shock proteins. Free Radic. Biol. Med. 2003; 35: 368-80.
-
(2003)
Free Radic. Biol. Med.
, vol.35
, pp. 368-380
-
-
Chiu, P.Y.1
Tang, M.H.2
Mak, D.H.3
Poon, M.K.4
Ko, K.M.5
-
96
-
-
79951674293
-
Schisandrin B protects against solar irradiation-induced oxidative stress in rat skin tissue
-
Lam PY, Yan CW, Chiu PY, Leung HY, Ko KM. Schisandrin B protects against solar irradiation-induced oxidative stress in rat skin tissue. Fitoterapia 2011; 82: 393-400.
-
(2011)
Fitoterapia
, vol.82
, pp. 393-400
-
-
Lam, P.Y.1
Yan, C.W.2
Chiu, P.Y.3
Leung, H.Y.4
Ko, K.M.5
-
97
-
-
34250018342
-
Schisandrin B decreases the sensitivity of mitochondria to calcium ion-induced permeability transition and protects against carbon tetrachloride toxicity in mouse livers
-
Chiu PY, Leung HY, Siu AH, Poon MK, Ko KM. Schisandrin B decreases the sensitivity of mitochondria to calcium ion-induced permeability transition and protects against carbon tetrachloride toxicity in mouse livers. Biol. Pharm. Bull. 2007; 30: 1108-12.
-
(2007)
Biol. Pharm. Bull.
, vol.30
, pp. 1108-1112
-
-
Chiu, P.Y.1
Leung, H.Y.2
Siu, A.H.3
Poon, M.K.4
Ko, K.M.5
-
98
-
-
34848924275
-
Schisandrin B decreases the sensitivity of mitochondria to calcium ion-induced permeability transition and protects against ischemia-reperfusion injury in rat hearts
-
Chiu PY, Leung HY, Siu AH, Poon MK, Ko KM. Schisandrin B decreases the sensitivity of mitochondria to calcium ion-induced permeability transition and protects against ischemia-reperfusion injury in rat hearts. Acta Pharmacol. Sin. 2007; 28: 1559-65.
-
(2007)
Acta Pharmacol. Sin.
, vol.28
, pp. 1559-1565
-
-
Chiu, P.Y.1
Leung, H.Y.2
Siu, A.H.3
Poon, M.K.4
Ko, K.M.5
-
99
-
-
70349251736
-
Schisandrin B protects rat cortical neurons against Abeta1-42-induced neurotoxicity
-
Wang B, Wang XM. Schisandrin B protects rat cortical neurons against Abeta1-42-induced neurotoxicity. Pharmazie 2009; 64: 450-4.
-
(2009)
Pharmazie
, vol.64
, pp. 450-454
-
-
Wang, B.1
Wang, X.M.2
-
100
-
-
79951662032
-
(-)Schisandrin B ameliorates paraquat-induced oxidative stress by suppressing glutathione depletion and enhancing glutathione recovery in differentiated PC12 cells
-
Lam PY, Ko KM. (-)Schisandrin B ameliorates paraquat-induced oxidative stress by suppressing glutathione depletion and enhancing glutathione recovery in differentiated PC12 cells. Biofactors 2001; 37: 51-7.
-
(2001)
Biofactors
, vol.37
, pp. 51-57
-
-
Lam, P.Y.1
Ko, K.M.2
-
101
-
-
69249203689
-
Gomisin N isolated from Schisandra chinensis significantly induces anti-proliferative and pro-apototic effects in hepatic carcinoma
-
Yim SY, Lee YJ, Lee YK et al. Gomisin N isolated from Schisandra chinensis significantly induces anti-proliferative and pro-apototic effects in hepatic carcinoma. Mol. Med. Report 2009; 2: 725-32.
-
(2009)
Mol. Med. Report
, vol.2
, pp. 725-732
-
-
Yim, S.Y.1
Lee, Y.J.2
Lee, Y.K.3
-
102
-
-
76749131100
-
Apoptosis induction of human leukemia U937 cells by gomisin N, a dibenzocyclootadiene lignin, isolated from Schizandra chinensis Baill
-
Kim JH, Choi YW, Park C et al. Apoptosis induction of human leukemia U937 cells by gomisin N, a dibenzocyclootadiene lignin, isolated from Schizandra chinensis Baill. Food Chem. Toxicol. 2010; 48: 807-13.
-
(2010)
Food Chem. Toxicol.
, vol.48
, pp. 807-813
-
-
Kim, J.H.1
Choi, Y.W.2
Park, C.3
-
103
-
-
73149106613
-
Inhibition of ATR protein kinase activity by schisandrin B in DNA damage response
-
Nishida H, Tatewaki N, Nakajima Y et al. Inhibition of ATR protein kinase activity by schisandrin B in DNA damage response. Nucleic Acids Res. 2009; 37: 5678-89.
-
(2009)
Nucleic Acids Res.
, vol.37
, pp. 5678-5689
-
-
Nishida, H.1
Tatewaki, N.2
Nakajima, Y.3
-
104
-
-
80755143829
-
Gomisin N has anti-allergic effect and inhibits inflammatory cytokine expression in mouse bone marrow-derived mast cells
-
Epub 14 March 2011; doi:
-
Chae HS, Kang OH, Oh YC et al. Gomisin N has anti-allergic effect and inhibits inflammatory cytokine expression in mouse bone marrow-derived mast cells. Immunopharmacol. Immunotoxicol. 2011; 33: 709-13. Epub 14 March 2011; doi:.
-
(2011)
Immunopharmacol. Immunotoxicol.
, vol.33
, pp. 709-713
-
-
Chae, H.S.1
Kang, O.H.2
Oh, Y.C.3
-
105
-
-
33846385587
-
Mammlian cytochromes P450: Importance of tissue specificity
-
Seliskar M, Rozman D. Mammlian cytochromes P450: Importance of tissue specificity. Biochim. Biophys. Acta 2006; 1770: 458-66.
-
(2006)
Biochim. Biophys. Acta
, vol.1770
, pp. 458-466
-
-
Seliskar, M.1
Rozman, D.2
-
106
-
-
0035059625
-
Metabolism of dimethyl-4,4′-dimethoxy-5,6,5′,6′-dimethylene dioxybiphenyl-2,2′-dicarboxylate (DDB) by human liver microsomes: Characterization of metabolic pathways and of cytochrome P450 isoforms involved
-
Baek MS, Kim JY, Myung SW, Yim YH, Jeong JH, Kim DH. Metabolism of dimethyl-4, 4′-dimethoxy-5, 6, 5′, 6′-dimethylene dioxybiphenyl-2, 2′-dicarboxylate (DDB) by human liver microsomes: Characterization of metabolic pathways and of cytochrome P450 isoforms involved. Drug Metab. Dispos. 2007; 29: 381-8.
-
(2007)
Drug Metab. Dispos.
, vol.29
, pp. 381-388
-
-
Baek, M.S.1
Kim, J.Y.2
Myung, S.W.3
Yim, Y.H.4
Jeong, J.H.5
Kim, D.H.6
-
107
-
-
77952365301
-
Schisandrin B-induced glutathione antioxidant response and cardioprotection are mediated by reactive oxidant species production in rat hearts
-
Chen N, Ko KM. Schisandrin B-induced glutathione antioxidant response and cardioprotection are mediated by reactive oxidant species production in rat hearts. Biol. Pharm. Bull. 2010; 33: 825-9.
-
(2010)
Biol. Pharm. Bull.
, vol.33
, pp. 825-829
-
-
Chen, N.1
Ko, K.M.2
-
108
-
-
84857431178
-
Cytochrome P-450-catalyzed reactive oxygen species production mediates the (-)Schisandrin B-induced glutathione and heat shock responses in AML12 hepatocytes
-
Leong PK, Chiu PY, Leung HY, Ko KM. Cytochrome P-450-catalyzed reactive oxygen species production mediates the (-)Schisandrin B-induced glutathione and heat shock responses in AML12 hepatocytes. Cell Biol. Int. 2012; 36: 321-6.
-
(2012)
Cell Biol. Int.
, vol.36
, pp. 321-326
-
-
Leong, P.K.1
Chiu, P.Y.2
Leung, H.Y.3
Ko, K.M.4
-
109
-
-
79952432864
-
Schisandrin B elicits a glutathione antioxidant response and protects against apoptosis via the redox-sensitive ERK/Nrf2 pathway in AML12 hepatocytes
-
Leong PK, Chiu PY, Chen N, Leung H, Ko KM. Schisandrin B elicits a glutathione antioxidant response and protects against apoptosis via the redox-sensitive ERK/Nrf2 pathway in AML12 hepatocytes. Free Radic. Res. 2011; 45: 483-95.
-
(2011)
Free Radic. Res.
, vol.45
, pp. 483-495
-
-
Leong, P.K.1
Chiu, P.Y.2
Chen, N.3
Leung, H.4
Ko, K.M.5
-
110
-
-
79953674467
-
Schisandrin B elicits a glutathione antioxidant response and protects against apoptosis via the redox-sensitive ERK/Nrf2 pathway in H9c2 cells
-
Chiu PY, Chen N, Leong PK, Leung HY, Ko KM. Schisandrin B elicits a glutathione antioxidant response and protects against apoptosis via the redox-sensitive ERK/Nrf2 pathway in H9c2 cells. Mol. Cell. Biochem. 2011; 350: 237-50.
-
(2011)
Mol. Cell. Biochem.
, vol.350
, pp. 237-250
-
-
Chiu, P.Y.1
Chen, N.2
Leong, P.K.3
Leung, H.Y.4
Ko, K.M.5
-
111
-
-
79953683977
-
Gomisin N enhances TNF-α-induced apoptosis via inhibition of the NF-κB and EGFR survival pathways
-
Waiwut P, Shin MS, Inujima A et al. Gomisin N enhances TNF-α-induced apoptosis via inhibition of the NF-κB and EGFR survival pathways. Mol. Cell. Biochem. 2011; 350: 169-75.
-
(2011)
Mol. Cell. Biochem.
, vol.350
, pp. 169-175
-
-
Waiwut, P.1
Shin, M.S.2
Inujima, A.3
-
112
-
-
33750159449
-
Neurohormetic phytochemicals: Low-dose toxins that induce adaptive neuronal stress responses
-
Mattson MP, Chen A. Neurohormetic phytochemicals: Low-dose toxins that induce adaptive neuronal stress responses. Trends Neurosci. 2006; 29: 632-9.
-
(2006)
Trends Neurosci.
, vol.29
, pp. 632-639
-
-
Mattson, M.P.1
Chen, A.2
|