The reductive hotspot hypothesis of mammalian aging: Membrane metabolism magnifies mutant mitochondrial mischief

European Journal of Biochemistry

Volumn 269, Issue 8, 2002, Pages 2003-2009

  De Grey, Aubrey D N J ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Aging; Extracellular superoxide; Lipoproteins; Mitochondrial mutations; Plasma membrane redox

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; CHOLESTEROL; CYTOCHROME C OXIDASE; DINUCLEOTIDE; FERRICYANIDE; LOW DENSITY LIPOPROTEIN; MITOCHONDRIAL DNA; NICOTINAMIDE ADENINE DINUCLEOTIDE; PYRUVIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; SUCCINATE DEHYDROGENASE; SUPEROXIDE; SUPEROXIDE DISMUTASE;

AGING; CELL MEMBRANE; CELL METABOLISM; CELL SURVIVAL; ELECTRON TRANSPORT; HOMEOSTASIS; HYPOTHESIS; LIPID PEROXIDATION; MAMMAL CELL; MITOCHONDRION; MUTATION; NONHUMAN; OXIDATION; OXIDATION REDUCTION REACTION; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SHORT SURVEY;

AGING; ANIMALS; CELL MEMBRANE; DNA, MITOCHONDRIAL; HUMANS; MITOCHONDRIA; MUTATION; OXIDATIVE PHOSPHORYLATION; SUPEROXIDES;

MAMMALIA;

EID: 0036236939     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1033.2002.02868.x     Document Type: Short Survey

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