메뉴 건너뛰기




Volumn 77, Issue 2, 2006, Pages 63-70

Effects of schisandrin B enantiomers on cellular glutathione and menadione toxicity in AML12 hepatocytes

Author keywords

Glutamate cysteine ligase; AML12; Enantiomers; Glutathione; Glutathione reductase; Hepatocyte; Menadione; Schisandrin B

Indexed keywords

BUTHIONINE SULFOXIMINE; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; GLUTATHIONE REDUCTASE; MENADIONE; NATURAL PRODUCT; PHORONE; SCHIZANDRIN B;

EID: 33744815331     PISSN: 00317012     EISSN: None     Source Type: Journal    
DOI: 10.1159/000092773     Document Type: Article
Times cited : (17)

References (26)
  • 2
    • 0028970756 scopus 로고
    • Effect of schisandrin B on hepatic glutathione antioxidant system in mice: Protection against carbon tetrachloride toxicity
    • Ip SP, Poon MKT, Wu SS, Che CT, Ng KH, Kong YC, Ko KM: Effect of schisandrin B on hepatic glutathione antioxidant system in mice: protection against carbon tetrachloride toxicity. Planta Med 1995;61:398-401.
    • (1995) Planta Med , vol.61 , pp. 398-401
    • Ip, S.P.1    Poon, M.K.T.2    Wu, S.S.3    Che, C.T.4    Ng, K.H.5    Kong, Y.C.6    Ko, K.M.7
  • 3
    • 0033921698 scopus 로고    scopus 로고
    • Schisandrin B protects against menadione-induced hepatotoxicity by enhancing DT-diaphorase activity
    • Ip SP, Yiu HY, Ko KM: Schisandrin B protects against menadione-induced hepatotoxicity by enhancing DT-diaphorase activity. Mol Cell Biochem 2000;208:151-155.
    • (2000) Mol Cell Biochem , vol.208 , pp. 151-155
    • Ip, S.P.1    Yiu, H.Y.2    Ko, K.M.3
  • 4
    • 0030582834 scopus 로고    scopus 로고
    • The crucial antioxidant action of schisandrin B in protecting against carbon tetrachloride hepatotoxicity in mice: A comparative study with butylated hydroxytoluene
    • Ip SP, Ko KM: The crucial antioxidant action of schisandrin B in protecting against carbon tetrachloride hepatotoxicity in mice: a comparative study with butylated hydroxytoluene. Biochem Pharmacol 1996;52:1687-1693.
    • (1996) Biochem Pharmacol , vol.52 , pp. 1687-1693
    • Ip, S.P.1    Ko, K.M.2
  • 5
    • 0029758732 scopus 로고    scopus 로고
    • Schisandrin B protects against carbon tetrachloride toxicity by enhancing the mitochondrial glutathione redox status in mouse liver
    • Ip SP, Poon MKT, Che CT, Ng KH, Kong YC, Ko KM: Schisandrin B protects against carbon tetrachloride toxicity by enhancing the mitochondrial glutathione redox status in mouse liver. Free Radic Biol Med 1996;21:709-712.
    • (1996) Free Radic Biol Med , vol.21 , pp. 709-712
    • Ip, S.P.1    Poon, M.K.T.2    Che, C.T.3    Ng, K.H.4    Kong, Y.C.5    Ko, K.M.6
  • 6
    • 0142011656 scopus 로고    scopus 로고
    • Hepatoprotective mechanism of schisandrin B: Role of mitochondrial glutathione antioxidant status and heat shock proteins
    • Chiu PY, Tang MH, Mak DHF, Poon MKT, Ko KM: Hepatoprotective mechanism of schisandrin B: role of mitochondrial glutathione antioxidant status and heat shock proteins. Free Radic Biol Med 2003;35:368-380.
    • (2003) Free Radic Biol Med , vol.35 , pp. 368-380
    • Chiu, P.Y.1    Tang, M.H.2    Mak, D.H.F.3    Poon, M.K.T.4    Ko, K.M.5
  • 7
    • 0030795701 scopus 로고    scopus 로고
    • Methylenedioxy group as determinant of schisandrin in enhancing hepatic mitochondrial glutathione in carbon tetrachloride-intoxicated mice
    • Ip SP, Ma CY, Che CT, Ko KM: Methylenedioxy group as determinant of schisandrin in enhancing hepatic mitochondrial glutathione in carbon tetrachloride-intoxicated mice. Biochem Pharmacol 1997;54:317-319.
    • (1997) Biochem Pharmacol , vol.54 , pp. 317-319
    • Ip, S.P.1    Ma, C.Y.2    Che, C.T.3    Ko, K.M.4
  • 8
    • 0033997704 scopus 로고    scopus 로고
    • Differential effect of schisandrin B and dimethyl diphenyl bicarboxylate (DDB) on hepatic mitochondrial glutathione redox status in carbon tetrachloride intoxicated mice
    • Ip SP, Yiu HY, Ko KM: Differential effect of schisandrin B and dimethyl diphenyl bicarboxylate (DDB) on hepatic mitochondrial glutathione redox status in carbon tetrachloride intoxicated mice. Mol Cell Biochem 2000;205: 111-114.
    • (2000) Mol Cell Biochem , vol.205 , pp. 111-114
    • Ip, S.P.1    Yiu, H.Y.2    Ko, K.M.3
  • 9
    • 0036407327 scopus 로고    scopus 로고
    • Protection against carbon tetrachloride liver toxicity by enantiomers of schisandrin B associated with differential changes in hepatic glutathione antioxidant system in mice
    • Ko KM, Poon MKT, Ip SP, Wu K: Protection against carbon tetrachloride liver toxicity by enantiomers of schisandrin B associated with differential changes in hepatic glutathione antioxidant system in mice. Pharmaceut Biol 2002;40:298-301.
    • (2002) Pharmaceut Biol , vol.40 , pp. 298-301
    • Ko, K.M.1    Poon, M.K.T.2    Ip, S.P.3    Wu, K.4
  • 10
    • 0036709597 scopus 로고    scopus 로고
    • Cellular glutathione and thiols metabolism
    • Dickinson DA, Forman HJ: Cellular glutathione and thiols metabolism. Biochem Pharmacol 2002;64:1019-1026.
    • (2002) Biochem Pharmacol , vol.64 , pp. 1019-1026
    • Dickinson, D.A.1    Forman, H.J.2
  • 11
    • 0022300420 scopus 로고
    • Glutathione biosynthesis: Gamma-glutamylcysteine synthetase from rat kidney
    • Seelig GF, Meister A: Glutathione biosynthesis: gamma-glutamylcysteine synthetase from rat kidney. Methods Enzymol 1985;113:379-390.
    • (1985) Methods Enzymol , vol.113 , pp. 379-390
    • Seelig, G.F.1    Meister, A.2
  • 12
    • 0027979778 scopus 로고
    • Establishment and characterization of differentiated, non-transformed hepatocyte cell lines derived from mice transgenic for transforming growth factor alpha
    • USA
    • Wu JC, Merlino G, Fausto N: Establishment and characterization of differentiated, non-transformed hepatocyte cell lines derived from mice transgenic for transforming growth factor alpha. Proc Natl Acad Sci USA 1994;91:674-678.
    • (1994) Proc Natl Acad Sci , vol.91 , pp. 674-678
    • Wu, J.C.1    Merlino, G.2    Fausto, N.3
  • 13
    • 0000776417 scopus 로고    scopus 로고
    • Myocardial protective effect of Sheng Mai San (SMS) and a lignan-enriched extract of Fructus schisandrae, in vivo and ex vivo
    • Li PC, Mak DHF, Poon MKT, Ip SP, Ko KM: Myocardial protective effect of Sheng Mai San (SMS) and a lignan-enriched extract of Fructus schisandrae, in vivo and ex vivo. Phytomedicine 1996;3:217-221.
    • (1996) Phytomedicine , vol.3 , pp. 217-221
    • Li, P.C.1    Mak, D.H.F.2    Poon, M.K.T.3    Ip, S.P.4    Ko, K.M.5
  • 14
    • 0019167355 scopus 로고
    • Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine
    • Griffith OW: Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine. Anal Biochem 1980;106:207-212.
    • (1980) Anal Biochem , vol.106 , pp. 207-212
    • Griffith, O.W.1
  • 15
    • 0036864668 scopus 로고    scopus 로고
    • In vivo antioxidant action in a lignan-enriched extract of schisandra fruit and an anthraquinone-containing extract of polygonum roost in comparison with schisandrin B and emodin
    • Chiu PY, Mak DHF, Poon MKT, Ko KM: In vivo antioxidant action in a lignan-enriched extract of schisandra fruit and an anthraquinone-containing extract of polygonum roost in comparison with schisandrin B and emodin. Planta Med 2002;68:951-956.
    • (2002) Planta Med , vol.68 , pp. 951-956
    • Chiu, P.Y.1    Mak, D.H.F.2    Poon, M.K.T.3    Ko, K.M.4
  • 16
    • 1542376929 scopus 로고    scopus 로고
    • Glutathione metabolism and its implications for health
    • Wu G, Fang YZ, Yang S, Lupton JR, Turner ND: Glutathione metabolism and its implications for health. J Nutr 2004;134:489-492.
    • (2004) J Nutr , vol.134 , pp. 489-492
    • Wu, G.1    Fang, Y.Z.2    Yang, S.3    Lupton, J.R.4    Turner, N.D.5
  • 18
    • 0021221090 scopus 로고
    • Induction of DNA damage by menadione (2-methyl-1,4-naphthoquinone) in primary cultures of rat hepatocytes
    • Morrison H, Jernstrom B, Nordenskjold M, Thor H, Orrenius S: Induction of DNA damage by menadione (2-methyl-1,4-naphthoquinone) in primary cultures of rat hepatocytes. Biochem Pharmacol 1984;33:1763-1769.
    • (1984) Biochem Pharmacol , vol.33 , pp. 1763-1769
    • Morrison, H.1    Jernstrom, B.2    Nordenskjold, M.3    Thor, H.4    Orrenius, S.5
  • 19
    • 0023820402 scopus 로고
    • Correlation between cytosolic Ca2+ concentration and cytotoxicity in hepatocytes exposed to oxidative stress
    • Nicotera P, McConkey D, Svensson SA, Bellomo G, Orrenius S: Correlation between cytosolic Ca2+ concentration and cytotoxicity in hepatocytes exposed to oxidative stress. Toxicology 1988;52:55-63.
    • (1988) Toxicology , vol.52 , pp. 55-63
    • Nicotera, P.1    McConkey, D.2    Svensson, S.A.3    Bellomo, G.4    Orrenius, S.5
  • 21
    • 0036710563 scopus 로고    scopus 로고
    • Cell signaling and the glutathione redox system
    • Filomeni G, Rotilio G, Ciriolo M: Cell signaling and the glutathione redox system. Biochem Pharmacol 2002;64:765-770.
    • (2002) Biochem Pharmacol , vol.64 , pp. 765-770
    • Filomeni, G.1    Rotilio, G.2    Ciriolo, M.3
  • 23
    • 0022340278 scopus 로고
    • Effect of phorone-induced glutathione depletion on the metabolism and hepatotoxicity of carbon tetrachloride and vinylidene chloride in rats
    • Siegers CP, Horn W, Younes M: Effect of phorone-induced glutathione depletion on the metabolism and hepatotoxicity of carbon tetrachloride and vinylidene chloride in rats. Appl Toxicol 1985;5:352-356.
    • (1985) Appl Toxicol , vol.5 , pp. 352-356
    • Siegers, C.P.1    Horn, W.2    Younes, M.3
  • 24
    • 0022588598 scopus 로고
    • The stereostructure of Wuweizisu B
    • Tan R, Li L, Fang Q: The stereostructure of Wuweizisu B. Planta Med 1986;52:49-51.
    • (1986) Planta Med , vol.52 , pp. 49-51
    • Tan, R.1    Li, L.2    Fang, Q.3
  • 25
    • 0025146116 scopus 로고
    • Scavenging effects on active oxygen radicals by schizandrins with different structures and configurations
    • Li XJ, Zhao BL, Liu GT, Xin WJ: Scavenging effects on active oxygen radicals by schizandrins with different structures and configurations. Free Radic Biol Med 1990;9:99-104.
    • (1990) Free Radic Biol Med , vol.9 , pp. 99-104
    • Li, X.J.1    Zhao, B.L.2    Liu, G.T.3    Xin, W.J.4
  • 26
    • 25844433732 scopus 로고    scopus 로고
    • Role of cytochrome P-450 in schisandrin B-induced antioxidant and heat shock responses in mouse liver
    • Chiu PY, Mak DHF, Poon MKT, Ko KM: Role of cytochrome P-450 in schisandrin B-induced antioxidant and heat shock responses in mouse liver. Life Sci 2005;77:2887-2895.
    • (2005) Life Sci , vol.77 , pp. 2887-2895
    • Chiu, P.Y.1    Mak, D.H.F.2    Poon, M.K.T.3    Ko, K.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.