Mitochondrial hexokinase II (HKII) and phosphoprotein enriched in astrocytes (PEA15) form a molecular switch governing cellular fate depending on the metabolic state

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 5, 2012, Pages 1518-1523

  Mergenthaler, Philipp ^a   Kahl, Anja ^a   Kamitz, Anne ^a   Van Laake, Vincent ^a   Stohlmann, Katharina ^a   Thomsen, Susanne ^a   Klawitter, Heiko ^a   Przesdzing, Ingo ^a   Neeb, Lars ^a   Freyer, Dorette ^a   Priller, Josef ^a   Collins, Tony J ^b   Megow, Dirk ^a   Dirnagl, Ulrich ^a   Andrews, David W ^b   Meisel, Andreas ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b MCMASTER UNIVERSITY   (Canada)

Author keywords

Cell death; Endogenous tolerance; Fluorescence lifetime imaging microscopy FRET; Mitochondria; Preconditioning

Indexed keywords

GLUCOSE; GLYCOLYTIC ENZYME; HEXOKINASE; HYPOXIA INDUCIBLE FACTOR; MITOCHONDRIAL ENZYME; PHOSPHOPROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; ASTROCYTE; CELL FATE; CELL HYPOXIA; CELL PROTECTION; EMBRYO; ENERGY METABOLISM; HYPOXIA; INFLAMMATION; METABOLIC STRESS; MITOCHONDRION; NERVE CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ASTROCYTES; CATALYSIS; CELL LINEAGE; HEXOKINASE; MITOCHONDRIA; PHOSPHOPROTEINS; RATS;

EID: 84857135413     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1108225109     Document Type: Article

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