Functional organization of mammalian hexokinases: Both N-and C-terminal halves of the rat type II isozyme possess catalytic sites

Archives of Biochemistry and Biophysics

Volumn 329, Issue 1, 1996, Pages 17-23

  Tsai, Henry J ^a   Wilson, John E ^a  

^a Michigan State University   (United States)

Author keywords

Hexokinase, mammalian isozymes of; Hexokinase, mammalian, evolution of; Hexokinase, Type II isozyme; Hexokinase; mammalian, functional organization of

Indexed keywords

1,5 ANHYDROSORBITOL; HEXOKINASE; ISOENZYME;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME MECHANISM; EVOLUTION; GENE DUPLICATION; GENE FUSION; MAMMAL; MICHAELIS CONSTANT; NONHUMAN; PRIORITY JOURNAL; RAT; SITE DIRECTED MUTAGENESIS;

ANIMALS; BASE SEQUENCE; BINDING SITES; CELL LINE; DNA, COMPLEMENTARY; HEXOKINASE; ISOENZYMES; KINETICS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; OLIGONUCLEOTIDE PROBES; RATS; RECOMBINANT FUSION PROTEINS; TRANSFECTION;

EID: 0029886531     PISSN: 00039861     EISSN: None     Source Type: Journal    
DOI: 10.1006/abbi.1996.0186     Document Type: Article

References (32)

1. Wilson, J. E. (1995) Rev. Physiol. Biochem. Pharmacol. 126, 65-198.
2. Bork, P., Sander, C., and Valencia, A. (1993) Protein Sci. 2, 31-40.
3. Schwab, D. A., and Wilson, J. E. (1991) Arch. Biochem. Biophys. 285, 365-370.
4. Thelen, A. P., and Wilson, J. E. (1991) Arch. Biochem. Biophys. 286, 645-651.
5. Kopetzki, E., Entian, K.-D., and Mecke, D. (1985) Gene 39, 95-102.
6. Stachelek, C., Stachelek, J., Swan, J., Botstein, D., and Konigsberg, W. (1986) Nucleic Acids Res. 14, 945-963.
7. Shoemaker, C. B., Reynolds, S. R., Wei, G., Tielens, A. G. M., and Harn, D. A. (1995) Exp. Parasitol. 80, 36-45.
8. Arora, K. K., Filburn, C. R., and Pedersen, P. L. (1991) J. Biol. Chem. 266, 5359-5362.
9. Arora, K. K., Filburn, C. R., and Pedersen, P. L. (1993) J. Biol. Chem. 268, 18259-18266.
10. Baijal, M., and Wilson, J. E. (1992) Arch. Biochem. Biophys. 298, 271-278.
11. Baijal, M., and Wilson, J. E. (1995) Arch. Biochem. Biophys. 321, 413-420.
12. Zeng, C., and Fromm, H. J. (1995) J. Biol. Chem. 270, 10509-10513.
13. White, T. K., and Wilson, J. E. (1989) Arch. Biochem. Biophys. 274, 373-393.
14. Hutny, J., and Wilson, J. E. (1990) Arch. Biochem. Biophys. 283, 173-183.
15. Tsai, H. J., and Wilson, J. E. (1995) Arch. Biochem. Biophys. 316, 206-214.
16. Wilson, J. E. (1989) Prep. Biochem. 19, 13-21.
17. Perrella, F. W. (1988) Anal. Biochem. 174, 437-447.
18. Hill, H. D., and Straka, J. G. (1988) Anal. Biochem. 170, 203-208.
19. Finney, K. G., Messer, J. L., DeWitt, D. L., and Wilson, J. E. (1984) J. Biol. Chem. 259, 8232-8237.
20. Polakis, P. G., and Wilson, J. E. (1984) Arch. Biochem. Biophys. 234, 341-352.
21. Lueck, J. D., and Fromm, H. J. (1974) J. Biol. Chem. 249, 1341-1347.
22. Dixon, M., and Webb, E. C. (1964) Enzymes, Academic Press, New York.
23. Okazaki, H., Takebayashi, Y., Ando, M., Date, S., Tokuda, H., and Ishibashi, S. (1992) Mol. Cell. Biochem. 117, 87-92.
24. White, T. K., and Wilson, J. E. (1990) Arch. Biochem. Biophys. 277, 26-34.
25. Wilson, J. E. (1984) in Regulation of Carbohydrate Metabolism (Beitner, R., Ed.), Vol. I, pp. 45-85, CRC Press, Boca Raton, FL.
26. Tielens, A. G. M., van den Heuvel, J. M., van Mazijk, H. J., Wilson, J. E., and Shoemaker, C. B. (1994) J. Biol. Chem. 269, 24736-24741.
27. Jetton, T. L., Liang, Y., Pettepher, C. C., Zimmerman, E. C., Cox, F. G., Horvath, K., Matschinsky, F. M., and Magnuson, M. A. (1994) J. Biol. Chem. 269, 3641-3654.
28. Griffin, L. D., Gelb, B. D., Wheeler, D. A., Davison, D., Adams, V., and McCabe, E. R. B. (1991) Genomics 11, 1014-1024.
29. Printz, R. L., Koch, S., Potter, L. R., O'Doherty, R. M., Tiesinga, J. J., Moritz, S., and Granner, D. K. (1993) J. Biol. Chem. 268, 5209-5219.
30. Kogure, K., Shinohara, Y., and Terada, H. (1993) J. Biol. Chem. 268, 8422-8424.
31. Ureta, T. (1982) Comp. Biochem. Physiol. 71B, 549-555.
32. Ardehali, H., Yano, Y., Printz, R. L., Koch, S., Whitesell, R. R., May, J. M., and Granner, D. K. (1996) J. Biol. Chem. 271, 1849-1852.