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Volumn 24, Issue 1, 2012, Pages 67-74

Immuno-microbiota cross and talk: The new paradigm of metabolic diseases

Author keywords

Diabetes; Innate immunity; Intestinal microbiota; Metabolic diseases; Obesity

Indexed keywords

BACTERIAL ANTIGEN; INSULIN;

EID: 84857058546     PISSN: 10445323     EISSN: 10963618     Source Type: Journal    
DOI: 10.1016/j.smim.2011.11.011     Document Type: Review
Times cited : (123)

References (100)
  • 1
    • 80053920983 scopus 로고    scopus 로고
    • Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus
    • Jacquemont S., Reymond A., Zufferey F., Harewood L., Walters R.G., Kutalik Z., et al. Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus. Nature 2011, 478:97-102.
    • (2011) Nature , vol.478 , pp. 97-102
    • Jacquemont, S.1    Reymond, A.2    Zufferey, F.3    Harewood, L.4    Walters, R.G.5    Kutalik, Z.6
  • 2
    • 0141678155 scopus 로고    scopus 로고
    • Metabolic and genetic influence on glucose metabolism in type 2 diabetic subjects-experiences from relatives and twin studies
    • Beck-Nielsen H., Vaag A., Poulsen P., Gaster M. Metabolic and genetic influence on glucose metabolism in type 2 diabetic subjects-experiences from relatives and twin studies. Best Pract Res Clin Endocrinol Metab 2003, 17:445-467.
    • (2003) Best Pract Res Clin Endocrinol Metab , vol.17 , pp. 445-467
    • Beck-Nielsen, H.1    Vaag, A.2    Poulsen, P.3    Gaster, M.4
  • 3
    • 0037221208 scopus 로고    scopus 로고
    • Impact of two common polymorphisms in the PPARgamma gene on glucose tolerance and plasma insulin profiles in monozygotic and dizygotic twins: thrifty genotype, thrifty phenotype, or both?
    • Poulsen P., Andersen G., Fenger M., Hansen T., Echwald S.M., Volund A., et al. Impact of two common polymorphisms in the PPARgamma gene on glucose tolerance and plasma insulin profiles in monozygotic and dizygotic twins: thrifty genotype, thrifty phenotype, or both?. Diabetes 2003, 52:194-198.
    • (2003) Diabetes , vol.52 , pp. 194-198
    • Poulsen, P.1    Andersen, G.2    Fenger, M.3    Hansen, T.4    Echwald, S.M.5    Volund, A.6
  • 4
    • 0032896076 scopus 로고    scopus 로고
    • Concordance rate for type II diabetes mellitus in monozygotic twins: actuarial analysis
    • Medici F., Hawa M., Ianari A., Pyke D.A., Leslie R.D. Concordance rate for type II diabetes mellitus in monozygotic twins: actuarial analysis. Diabetologia 1999, 42:146-150.
    • (1999) Diabetologia , vol.42 , pp. 146-150
    • Medici, F.1    Hawa, M.2    Ianari, A.3    Pyke, D.A.4    Leslie, R.D.5
  • 6
    • 77950251400 scopus 로고    scopus 로고
    • A human gut microbial gene catalogue established by metagenomic sequencing
    • Qin J., Li R., Raes J., Arumugam M., Burgdorf K.S., Manichanh C., et al. A human gut microbial gene catalogue established by metagenomic sequencing. Nature 2010, 464:59-65.
    • (2010) Nature , vol.464 , pp. 59-65
    • Qin, J.1    Li, R.2    Raes, J.3    Arumugam, M.4    Burgdorf, K.S.5    Manichanh, C.6
  • 9
    • 80053528043 scopus 로고    scopus 로고
    • The human gut virome: inter-individual variation and dynamic response to diet
    • Minot S., Sinha R., Chen J., Li H., Keilbaugh S.A., Wu G.D., et al. The human gut virome: inter-individual variation and dynamic response to diet. Genome Res 2011, 21:1616-1625.
    • (2011) Genome Res , vol.21 , pp. 1616-1625
    • Minot, S.1    Sinha, R.2    Chen, J.3    Li, H.4    Keilbaugh, S.A.5    Wu, G.D.6
  • 12
    • 0141942752 scopus 로고    scopus 로고
    • Intestinal microflora in early infancy: composition and development
    • Fanaro S., Chierici R., Guerrini P., Vigi V. Intestinal microflora in early infancy: composition and development. Acta Paediatr Suppl 2003, (91):48-55.
    • (2003) Acta Paediatr Suppl , Issue.91 , pp. 48-55
    • Fanaro, S.1    Chierici, R.2    Guerrini, P.3    Vigi, V.4
  • 13
    • 0142026205 scopus 로고    scopus 로고
    • Inaugural Article: honor the symbionts
    • Xu J., Gordon J.I. Inaugural Article: honor the symbionts. Proc Natl Acad Sci USA 2003, 100:10452-10459.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 10452-10459
    • Xu, J.1    Gordon, J.I.2
  • 14
    • 0032956143 scopus 로고    scopus 로고
    • Developmental microbial ecology of the neonatal gastrointestinal tract
    • Mackie R.I., Sghir A., Gaskins H.R. Developmental microbial ecology of the neonatal gastrointestinal tract. Am J Clin Nutr 1999, 69:1035S-1045S.
    • (1999) Am J Clin Nutr , vol.69
    • Mackie, R.I.1    Sghir, A.2    Gaskins, H.R.3
  • 17
    • 32944466887 scopus 로고    scopus 로고
    • Ecological and evolutionary forces shaping microbial diversity in the human intestine
    • Ley R.E., Peterson D.A., Gordon J.I. Ecological and evolutionary forces shaping microbial diversity in the human intestine. Cell 2006, 124:837-848.
    • (2006) Cell , vol.124 , pp. 837-848
    • Ley, R.E.1    Peterson, D.A.2    Gordon, J.I.3
  • 18
    • 33845901507 scopus 로고    scopus 로고
    • Human gut microbes associated with obesity
    • Ley R.E., Turnbaugh P.J., Klein S., Gordon J.I. Human gut microbes associated with obesity. Nature 2006, 444:1022-1023.
    • (2006) Nature , vol.444 , pp. 1022-1023
    • Ley, R.E.1    Turnbaugh, P.J.2    Klein, S.3    Gordon, J.I.4
  • 19
    • 77956569409 scopus 로고    scopus 로고
    • Enterobacteriaceae act in concert with the gut microbiota to induce spontaneous and maternally transmitted colitis
    • Garrett W.S., Gallini C.A., Yatsunenko T., Michaud M., DuBois A., Delaney M.L., et al. Enterobacteriaceae act in concert with the gut microbiota to induce spontaneous and maternally transmitted colitis. Cell Host Microbe 2010, 8:292-300.
    • (2010) Cell Host Microbe , vol.8 , pp. 292-300
    • Garrett, W.S.1    Gallini, C.A.2    Yatsunenko, T.3    Michaud, M.4    DuBois, A.5    Delaney, M.L.6
  • 20
    • 79957576718 scopus 로고    scopus 로고
    • NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis
    • Elinav E., Strowig T., Kau A.L., Henao-Mejia J., Thaiss C.A., Booth C.J., et al. NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis. Cell 2011, 145:745-757.
    • (2011) Cell , vol.145 , pp. 745-757
    • Elinav, E.1    Strowig, T.2    Kau, A.L.3    Henao-Mejia, J.4    Thaiss, C.A.5    Booth, C.J.6
  • 21
    • 79959221313 scopus 로고    scopus 로고
    • Inflammasome-mediated suppression of inflammation-induced colorectal cancer progression is mediated by direct regulation of epithelial cell proliferation
    • Hu B., Elinav E., Flavell R.A. Inflammasome-mediated suppression of inflammation-induced colorectal cancer progression is mediated by direct regulation of epithelial cell proliferation. Cell Cycle 2011, 10:1936-1939.
    • (2011) Cell Cycle , vol.10 , pp. 1936-1939
    • Hu, B.1    Elinav, E.2    Flavell, R.A.3
  • 23
  • 24
    • 33845874101 scopus 로고    scopus 로고
    • An obesity-associated gut microbiome with increased capacity for energy harvest
    • Turnbaugh P.J., Ley R.E., Mahowald M.A., Magrini V., Mardis E.R., Gordon J.I. An obesity-associated gut microbiome with increased capacity for energy harvest. Nature 2006, 444:1027-1031.
    • (2006) Nature , vol.444 , pp. 1027-1031
    • Turnbaugh, P.J.1    Ley, R.E.2    Mahowald, M.A.3    Magrini, V.4    Mardis, E.R.5    Gordon, J.I.6
  • 25
    • 8144226856 scopus 로고    scopus 로고
    • The gut microbiota as an environmental factor that regulates fat storage
    • Backhed F., Ding H., Wang T., Hooper L.V., Koh G.Y., Nagy A., et al. The gut microbiota as an environmental factor that regulates fat storage. Proc Natl Acad Sci USA 2004, 101:15718-15723.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 15718-15723
    • Backhed, F.1    Ding, H.2    Wang, T.3    Hooper, L.V.4    Koh, G.Y.5    Nagy, A.6
  • 26
    • 77950669604 scopus 로고    scopus 로고
    • The effect of diet on the human gut microbiome: a metagenomic analysis in humanized gnotobiotic mice
    • Turnbaugh P., Ridaura V., Faith J., Rey F., Knight R., Gordon J. The effect of diet on the human gut microbiome: a metagenomic analysis in humanized gnotobiotic mice. Sci Transl Med 2009, 1:6-14.
    • (2009) Sci Transl Med , vol.1 , pp. 6-14
    • Turnbaugh, P.1    Ridaura, V.2    Faith, J.3    Rey, F.4    Knight, R.5    Gordon, J.6
  • 28
    • 0031720795 scopus 로고    scopus 로고
    • Is type II diabetes mellitus a disease of the innate immune system?
    • Pickup J.C., Crook M.A. Is type II diabetes mellitus a disease of the innate immune system?. Diabetologia 1998, 41:1241-1248.
    • (1998) Diabetologia , vol.41 , pp. 1241-1248
    • Pickup, J.C.1    Crook, M.A.2
  • 30
    • 68349148211 scopus 로고    scopus 로고
    • Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters
    • Feuerer M., Herrero L., Cipolletta D., Naaz A., Wong J., Nayer A., et al. Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters. Nat Med 2009, 15:930-939.
    • (2009) Nat Med , vol.15 , pp. 930-939
    • Feuerer, M.1    Herrero, L.2    Cipolletta, D.3    Naaz, A.4    Wong, J.5    Nayer, A.6
  • 32
    • 68349137821 scopus 로고    scopus 로고
    • Normalization of obesity-associated insulin resistance through immunotherapy
    • Winer S., Chan Y., Paltser G., Truong D., Tsui H., Bahrami J., et al. Normalization of obesity-associated insulin resistance through immunotherapy. Nat Med 2009, 15:921-929.
    • (2009) Nat Med , vol.15 , pp. 921-929
    • Winer, S.1    Chan, Y.2    Paltser, G.3    Truong, D.4    Tsui, H.5    Bahrami, J.6
  • 33
    • 33845866857 scopus 로고    scopus 로고
    • Inflammation and metabolic disorders
    • Hotamisligil G.S. Inflammation and metabolic disorders. Nature 2006, 444:860-867.
    • (2006) Nature , vol.444 , pp. 860-867
    • Hotamisligil, G.S.1
  • 34
    • 33745861300 scopus 로고    scopus 로고
    • Inflammation and insulin resistance
    • Shoelson S., Lee J., Goldfine A. Inflammation and insulin resistance. J Clin Invest 2006, 116:1793-1801.
    • (2006) J Clin Invest , vol.116 , pp. 1793-1801
    • Shoelson, S.1    Lee, J.2    Goldfine, A.3
  • 35
    • 43549107065 scopus 로고    scopus 로고
    • Energy intake is associated with endotoxemia in apparently healthy men
    • Amar J., Burcelin R., Ruidavets J., Cani P., Fauvel J., Alessi M., et al. Energy intake is associated with endotoxemia in apparently healthy men. Am J Clin Nutr 2008, 87:1219-1223.
    • (2008) Am J Clin Nutr , vol.87 , pp. 1219-1223
    • Amar, J.1    Burcelin, R.2    Ruidavets, J.3    Cani, P.4    Fauvel, J.5    Alessi, M.6
  • 36
    • 48249125862 scopus 로고    scopus 로고
    • Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice
    • Cani P.D., Bibiloni R., Knauf C., Waget A., Neyrinck A.M., Delzenne N.M., et al. Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice. Diabetes 2008, 57:1470-1481.
    • (2008) Diabetes , vol.57 , pp. 1470-1481
    • Cani, P.D.1    Bibiloni, R.2    Knauf, C.3    Waget, A.4    Neyrinck, A.M.5    Delzenne, N.M.6
  • 37
    • 65249099918 scopus 로고    scopus 로고
    • " Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability"
    • Cani P.D., Possemiers S., et al. " Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability" Gut 2009, 58(8):1091-1103.
    • (2009) Gut , vol.58 , Issue.8 , pp. 1091-1103
    • Cani, P.D.1    Possemiers, S.2
  • 38
    • 34247884376 scopus 로고    scopus 로고
    • C3H/HeJ mice carrying a toll-like receptor 4 mutation are protected against the development of insulin resistance in white adipose tissue in response to a high-fat diet
    • Poggi M., Bastelica D., Gual P., Iglesias M.A., Gremeaux T., Knauf C., et al. C3H/HeJ mice carrying a toll-like receptor 4 mutation are protected against the development of insulin resistance in white adipose tissue in response to a high-fat diet. Diabetologia 2007, 50:1267-1276.
    • (2007) Diabetologia , vol.50 , pp. 1267-1276
    • Poggi, M.1    Bastelica, D.2    Gual, P.3    Iglesias, M.A.4    Gremeaux, T.5    Knauf, C.6
  • 39
    • 46749098265 scopus 로고    scopus 로고
    • " Gut microbiota modulation with norfloxacin and ampicillin enhances glucose tolerance in mice"
    • Membrez M., Blancher F., et al. " Gut microbiota modulation with norfloxacin and ampicillin enhances glucose tolerance in mice" FASEB J 2008, 22(7):2416-2426.
    • (2008) FASEB J , vol.22 , Issue.7 , pp. 2416-2426
    • Membrez, M.1    Blancher, F.2
  • 40
    • 0026059003 scopus 로고
    • Polymyxin B reduces cecal flora, TNF production and hepatic steatosis during total parenteral nutrition in the rat
    • Pappo I., Becovier H., Berry E.M., Freund H.R. Polymyxin B reduces cecal flora, TNF production and hepatic steatosis during total parenteral nutrition in the rat. J Surg Res 1991, 51:106-112.
    • (1991) J Surg Res , vol.51 , pp. 106-112
    • Pappo, I.1    Becovier, H.2    Berry, E.M.3    Freund, H.R.4
  • 41
    • 80052278497 scopus 로고    scopus 로고
    • Intestinal mucosal adherence and translocation of commensal bacteria at the early onset of type 2 diabetes: molecular mechanisms and probiotic treatment
    • Amar J., Chabo C., Waget A., Klopp P., Vachoux C., Bermudez-Humaran L.G., et al. Intestinal mucosal adherence and translocation of commensal bacteria at the early onset of type 2 diabetes: molecular mechanisms and probiotic treatment. EMBO Mol Med 2011, 3:559-572.
    • (2011) EMBO Mol Med , vol.3 , pp. 559-572
    • Amar, J.1    Chabo, C.2    Waget, A.3    Klopp, P.4    Vachoux, C.5    Bermudez-Humaran, L.G.6
  • 42
    • 34848912627 scopus 로고    scopus 로고
    • Selective increases of bifidobacteria in gut microflora improve high-fat-diet-induced diabetes in mice through a mechanism associated with endotoxaemia
    • Cani P.D., Neyrinck A.M., Fava F., Knauf C., Burcelin R.G., Tuohy K.M., et al. Selective increases of bifidobacteria in gut microflora improve high-fat-diet-induced diabetes in mice through a mechanism associated with endotoxaemia. Diabetologia 2007, 50:2374-2383.
    • (2007) Diabetologia , vol.50 , pp. 2374-2383
    • Cani, P.D.1    Neyrinck, A.M.2    Fava, F.3    Knauf, C.4    Burcelin, R.G.5    Tuohy, K.M.6
  • 43
    • 36249005027 scopus 로고    scopus 로고
    • A high-fat meal induces low-grade endotoxemia: evidence of a novel mechanism of postprandial inflammation
    • Erridge C., Attina T., Spickett C.M., Webb D.J. A high-fat meal induces low-grade endotoxemia: evidence of a novel mechanism of postprandial inflammation. Am J Clin Nutr 2007, 86:1286-1292.
    • (2007) Am J Clin Nutr , vol.86 , pp. 1286-1292
    • Erridge, C.1    Attina, T.2    Spickett, C.M.3    Webb, D.J.4
  • 45
    • 33644522719 scopus 로고    scopus 로고
    • Enterocyte TLR4 mediates phagocytosis and translocation of bacteria across the intestinal barrier
    • Neal M.D., Leaphart C., Levy R., Prince J., Billiar T.R., Watkins S., et al. Enterocyte TLR4 mediates phagocytosis and translocation of bacteria across the intestinal barrier. J Immunol 2006, 176:3070-3079.
    • (2006) J Immunol , vol.176 , pp. 3070-3079
    • Neal, M.D.1    Leaphart, C.2    Levy, R.3    Prince, J.4    Billiar, T.R.5    Watkins, S.6
  • 46
    • 0030997483 scopus 로고    scopus 로고
    • Human recombinant apolipoprotein E redirects lipopolysaccharide from Kupffer cells to liver parenchymal cells in rats in vivo
    • Rensen P.C., Oosten M., Bilt E., Eck M., Kuiper J., Berkel T.J. Human recombinant apolipoprotein E redirects lipopolysaccharide from Kupffer cells to liver parenchymal cells in rats in vivo. J Clin Invest 1997, 99:2438-2445.
    • (1997) J Clin Invest , vol.99 , pp. 2438-2445
    • Rensen, P.C.1    Oosten, M.2    Bilt, E.3    Eck, M.4    Kuiper, J.5    Berkel, T.J.6
  • 48
    • 0031030348 scopus 로고    scopus 로고
    • Lipopolysaccharide binding protein and soluble CD14 catalyze exchange of phospholipids
    • Yu B., Hailman E., Wright S.D. Lipopolysaccharide binding protein and soluble CD14 catalyze exchange of phospholipids. J Clin Invest 1997, 99:315-324.
    • (1997) J Clin Invest , vol.99 , pp. 315-324
    • Yu, B.1    Hailman, E.2    Wright, S.D.3
  • 49
    • 0036690208 scopus 로고    scopus 로고
    • Chylomicron-bound endotoxin selectively inhibits NF-kappaB activation in rat hepatocytes
    • Kumwenda Z.L., Wong C.B., Johnson J.A., Gosnell J.E., Welch W.J., Harris H.W. Chylomicron-bound endotoxin selectively inhibits NF-kappaB activation in rat hepatocytes. Shock 2002, 18:182-188.
    • (2002) Shock , vol.18 , pp. 182-188
    • Kumwenda, Z.L.1    Wong, C.B.2    Johnson, J.A.3    Gosnell, J.E.4    Welch, W.J.5    Harris, H.W.6
  • 50
    • 35848936707 scopus 로고    scopus 로고
    • Apolipoprotein C-I is crucially involved in lipopolysaccharide-induced atherosclerosis development in apolipoprotein E-knockout mice
    • Westerterp M., Berbee J.F., Pires N.M., van Mierlo G.J., Kleemann R., Romijn J.A., et al. Apolipoprotein C-I is crucially involved in lipopolysaccharide-induced atherosclerosis development in apolipoprotein E-knockout mice. Circulation 2007, 116:2173-2181.
    • (2007) Circulation , vol.116 , pp. 2173-2181
    • Westerterp, M.1    Berbee, J.F.2    Pires, N.M.3    van Mierlo, G.J.4    Kleemann, R.5    Romijn, J.A.6
  • 51
    • 33745187112 scopus 로고    scopus 로고
    • Activation of Toll-like receptor 4 is associated with insulin resistance in adipocytes
    • Song M.J., Kim K.H., Yoon J.M., Kim J.B. Activation of Toll-like receptor 4 is associated with insulin resistance in adipocytes. Biochem Biophys Res Commun 2006, 346:739-745.
    • (2006) Biochem Biophys Res Commun , vol.346 , pp. 739-745
    • Song, M.J.1    Kim, K.H.2    Yoon, J.M.3    Kim, J.B.4
  • 52
    • 46249105273 scopus 로고    scopus 로고
    • Adipose tissue lymphocytes and macrophages in obesity and insulin resistance: makers or markers, and which comes first?
    • Bouloumie A., Casteilla L., Lafontan M. Adipose tissue lymphocytes and macrophages in obesity and insulin resistance: makers or markers, and which comes first?. Arterioscler Thromb Vasc Biol 2008, 28:1211-1213.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 1211-1213
    • Bouloumie, A.1    Casteilla, L.2    Lafontan, M.3
  • 54
    • 33846026712 scopus 로고    scopus 로고
    • Obesity induces a phenotypic switch in adipose tissue macrophage polarization
    • Lumeng C.N., Bodzin J.L., Saltiel A.R. Obesity induces a phenotypic switch in adipose tissue macrophage polarization. J Clin Invest 2007, 117:175-184.
    • (2007) J Clin Invest , vol.117 , pp. 175-184
    • Lumeng, C.N.1    Bodzin, J.L.2    Saltiel, A.R.3
  • 55
    • 33847073149 scopus 로고    scopus 로고
    • Increased inflammatory properties of adipose tissue macrophages recruited during diet-induced obesity
    • Lumeng C.N., Deyoung S.M., Bodzin J.L., Saltiel A.R. Increased inflammatory properties of adipose tissue macrophages recruited during diet-induced obesity. Diabetes 2007, 56:16-23.
    • (2007) Diabetes , vol.56 , pp. 16-23
    • Lumeng, C.N.1    Deyoung, S.M.2    Bodzin, J.L.3    Saltiel, A.R.4
  • 56
    • 33745216724 scopus 로고    scopus 로고
    • MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity
    • Kanda H., Tateya S., Tamori Y., Kotani K., Hiasa K., Kitazawa R., et al. MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity. J Clin Invest 2006, 116:1494-1505.
    • (2006) J Clin Invest , vol.116 , pp. 1494-1505
    • Kanda, H.1    Tateya, S.2    Tamori, Y.3    Kotani, K.4    Hiasa, K.5    Kitazawa, R.6
  • 57
    • 9144223683 scopus 로고    scopus 로고
    • Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
    • Xu H., Barnes G.T., Yang Q., Tan G., Yang D., Chou C.J., et al. Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest 2003, 112:1821-1830.
    • (2003) J Clin Invest , vol.112 , pp. 1821-1830
    • Xu, H.1    Barnes, G.T.2    Yang, Q.3    Tan, G.4    Yang, D.5    Chou, C.J.6
  • 58
    • 0041302377 scopus 로고    scopus 로고
    • The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice
    • Xu A., Wang Y., Keshaw H., Xu L.Y., Lam K.S., Cooper G.J. The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice. J Clin Invest 2003, 112:91-100.
    • (2003) J Clin Invest , vol.112 , pp. 91-100
    • Xu, A.1    Wang, Y.2    Keshaw, H.3    Xu, L.Y.4    Lam, K.S.5    Cooper, G.J.6
  • 59
    • 79954591540 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem and progenitor cells induce monocyte emigration in response to circulating toll-like receptor ligands
    • Shi C., Jia T., Mendez-Ferrer S., Hohl T.M., Serbina N.V., Lipuma L., et al. Bone marrow mesenchymal stem and progenitor cells induce monocyte emigration in response to circulating toll-like receptor ligands. Immunity 2011, 34:590-601.
    • (2011) Immunity , vol.34 , pp. 590-601
    • Shi, C.1    Jia, T.2    Mendez-Ferrer, S.3    Hohl, T.M.4    Serbina, N.V.5    Lipuma, L.6
  • 60
    • 23644450775 scopus 로고    scopus 로고
    • Reduction of macrophage infiltration and chemoattractant gene expression changes in white adipose tissue of morbidly obese subjects after surgery-induced weight loss
    • Cancello R., Henegar C., Viguerie N., Taleb S., Poitou C., Rouault C., et al. Reduction of macrophage infiltration and chemoattractant gene expression changes in white adipose tissue of morbidly obese subjects after surgery-induced weight loss. Diabetes 2005, 54:2277-2286.
    • (2005) Diabetes , vol.54 , pp. 2277-2286
    • Cancello, R.1    Henegar, C.2    Viguerie, N.3    Taleb, S.4    Poitou, C.5    Rouault, C.6
  • 61
    • 67650224475 scopus 로고    scopus 로고
    • Macrophages and adipocytes in human obesity: adipose tissue gene expression and insulin sensitivity during calorie restriction and weight stabilization
    • Capel F., Klimcakova E., Viguerie N., Roussel B., Vitkova M., Kovacikova M., et al. Macrophages and adipocytes in human obesity: adipose tissue gene expression and insulin sensitivity during calorie restriction and weight stabilization. Diabetes 2009, 58:1558-1567.
    • (2009) Diabetes , vol.58 , pp. 1558-1567
    • Capel, F.1    Klimcakova, E.2    Viguerie, N.3    Roussel, B.4    Vitkova, M.5    Kovacikova, M.6
  • 62
    • 52749092267 scopus 로고    scopus 로고
    • Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals
    • Patsouris D., Li P.P., Thapar D., Chapman J., Olefsky J.M., Neels J.G. Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals. Cell Metab 2008, 8:301-309.
    • (2008) Cell Metab , vol.8 , pp. 301-309
    • Patsouris, D.1    Li, P.P.2    Thapar, D.3    Chapman, J.4    Olefsky, J.M.5    Neels, J.G.6
  • 63
    • 68349160704 scopus 로고    scopus 로고
    • Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice
    • Liu J., Divoux A., Sun J., Zhang J., Clement K., Glickman J.N., et al. Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice. Nat Med 2009, 15:940-945.
    • (2009) Nat Med , vol.15 , pp. 940-945
    • Liu, J.1    Divoux, A.2    Sun, J.3    Zhang, J.4    Clement, K.5    Glickman, J.N.6
  • 66
    • 77955492173 scopus 로고    scopus 로고
    • Toll-like receptor 2-deficient mice are protected from insulin resistance and beta cell dysfunction induced by a high-fat diet
    • Ehses J.A., Meier D.T., Wueest S., Rytka J., Boller S., Wielinga P.Y., et al. Toll-like receptor 2-deficient mice are protected from insulin resistance and beta cell dysfunction induced by a high-fat diet. Diabetologia 2010, 53:1795-1806.
    • (2010) Diabetologia , vol.53 , pp. 1795-1806
    • Ehses, J.A.1    Meier, D.T.2    Wueest, S.3    Rytka, J.4    Boller, S.5    Wielinga, P.Y.6
  • 68
    • 78649605448 scopus 로고    scopus 로고
    • TLR5 or NLRC4 is necessary and sufficient for promotion of humoral immunity by flagellin
    • Vijay-Kumar M., Carvalho F.A., Aitken J.D., Fifadara N.H., Gewirtz A.T. TLR5 or NLRC4 is necessary and sufficient for promotion of humoral immunity by flagellin. Eur J Immunol 2010, 40:3528-3534.
    • (2010) Eur J Immunol , vol.40 , pp. 3528-3534
    • Vijay-Kumar, M.1    Carvalho, F.A.2    Aitken, J.D.3    Fifadara, N.H.4    Gewirtz, A.T.5
  • 69
    • 78649545020 scopus 로고    scopus 로고
    • TLR5 activation induces secretory interleukin-1 receptor antagonist (sIL-1Ra) and reduces inflammasome-associated tissue damage
    • Carvalho F.A., Aitken J.D., Gewirtz A.T., Vijay-Kumar M. TLR5 activation induces secretory interleukin-1 receptor antagonist (sIL-1Ra) and reduces inflammasome-associated tissue damage. Mucosal Immunol 2011, 4:102-111.
    • (2011) Mucosal Immunol , vol.4 , pp. 102-111
    • Carvalho, F.A.1    Aitken, J.D.2    Gewirtz, A.T.3    Vijay-Kumar, M.4
  • 70
    • 80054903245 scopus 로고    scopus 로고
    • Elimination of the NLRP3-ASC inflammasome protects against chronic obesity-induced pancreatic damage
    • Youm Y.H., Adijiang A., Vandanmagsar B., Burk D., Ravussin A., Dixit V.D. Elimination of the NLRP3-ASC inflammasome protects against chronic obesity-induced pancreatic damage. Endocrinology 2011, 152:4039-4045.
    • (2011) Endocrinology , vol.152 , pp. 4039-4045
    • Youm, Y.H.1    Adijiang, A.2    Vandanmagsar, B.3    Burk, D.4    Ravussin, A.5    Dixit, V.D.6
  • 71
    • 79751512463 scopus 로고    scopus 로고
    • The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance
    • Vandanmagsar B., Youm Y.H., Ravussin A., Galgani J.E., Stadler K., Mynatt R.L., et al. The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance. Nat Med 2011, 17:179-188.
    • (2011) Nat Med , vol.17 , pp. 179-188
    • Vandanmagsar, B.1    Youm, Y.H.2    Ravussin, A.3    Galgani, J.E.4    Stadler, K.5    Mynatt, R.L.6
  • 72
    • 79151475165 scopus 로고    scopus 로고
    • Immunometabolism: an emerging frontier
    • Mathis D., Shoelson S.E. Immunometabolism: an emerging frontier. Nat Rev Immunol 2011, 11:81.
    • (2011) Nat Rev Immunol , vol.11 , pp. 81
    • Mathis, D.1    Shoelson, S.E.2
  • 73
    • 54049086276 scopus 로고    scopus 로고
    • Interferon-gamma, a Th1 cytokine, regulates fat inflammation: a role for adaptive immunity in obesity
    • Rocha V.Z., Folco E.J., Sukhova G., Shimizu K., Gotsman I., Vernon A.H., et al. Interferon-gamma, a Th1 cytokine, regulates fat inflammation: a role for adaptive immunity in obesity. Circ Res 2008, 103:467-476.
    • (2008) Circ Res , vol.103 , pp. 467-476
    • Rocha, V.Z.1    Folco, E.J.2    Sukhova, G.3    Shimizu, K.4    Gotsman, I.5    Vernon, A.H.6
  • 74
    • 68349150756 scopus 로고    scopus 로고
    • CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity
    • Nishimura S., Manabe I., Nagasaki M., Eto K., Yamashita H., Ohsugi M., et al. CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity. Nat Med 2009, 15:914-920.
    • (2009) Nat Med , vol.15 , pp. 914-920
    • Nishimura, S.1    Manabe, I.2    Nagasaki, M.3    Eto, K.4    Yamashita, H.5    Ohsugi, M.6
  • 75
    • 77956396699 scopus 로고    scopus 로고
    • Obesity increases the production of proinflammatory mediators from adipose tissue T cells and compromises TCR repertoire diversity: implications for systemic inflammation and insulin resistance
    • Yang H., Youm Y.H., Vandanmagsar B., Ravussin A., Gimble J.M., Greenway F., et al. Obesity increases the production of proinflammatory mediators from adipose tissue T cells and compromises TCR repertoire diversity: implications for systemic inflammation and insulin resistance. J Immunol 2010, 185:1836-1845.
    • (2010) J Immunol , vol.185 , pp. 1836-1845
    • Yang, H.1    Youm, Y.H.2    Vandanmagsar, B.3    Ravussin, A.4    Gimble, J.M.5    Greenway, F.6
  • 76
    • 77950349016 scopus 로고    scopus 로고
    • Th17 and regulatory T cells in mediating and restraining inflammation
    • Littman D.R., Rudensky A.Y. Th17 and regulatory T cells in mediating and restraining inflammation. Cell 2010, 140:845-858.
    • (2010) Cell , vol.140 , pp. 845-858
    • Littman, D.R.1    Rudensky, A.Y.2
  • 77
    • 43949105866 scopus 로고    scopus 로고
    • Regulatory T cells and immune tolerance
    • Sakaguchi S., Yamaguchi T., Nomura T., Ono M. Regulatory T cells and immune tolerance. Cell 2008, 133:775-787.
    • (2008) Cell , vol.133 , pp. 775-787
    • Sakaguchi, S.1    Yamaguchi, T.2    Nomura, T.3    Ono, M.4
  • 78
    • 77953110535 scopus 로고    scopus 로고
    • Induction of regulatory T cells decreases adipose inflammation and alleviates insulin resistance in ob/ob mice
    • Ilan Y., Maron R., Tukpah A.M., Maioli T.U., Murugaiyan G., Yang K., et al. Induction of regulatory T cells decreases adipose inflammation and alleviates insulin resistance in ob/ob mice. Proc Natl Acad Sci USA 2010, 107:9765-9770.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 9765-9770
    • Ilan, Y.1    Maron, R.2    Tukpah, A.M.3    Maioli, T.U.4    Murugaiyan, G.5    Yang, K.6
  • 79
    • 79958022995 scopus 로고    scopus 로고
    • Mice lacking NKT cells but with a complete complement of CD8+ T-cells are not protected against the metabolic abnormalities of diet-induced obesity
    • Mantell B.S., Stefanovic-Racic M., Yang X., Dedousis N., Sipula I.J., O'Doherty R.M. Mice lacking NKT cells but with a complete complement of CD8+ T-cells are not protected against the metabolic abnormalities of diet-induced obesity. PLoS One 2011, 6:e19831.
    • (2011) PLoS One , vol.6
    • Mantell, B.S.1    Stefanovic-Racic, M.2    Yang, X.3    Dedousis, N.4    Sipula, I.J.5    O'Doherty, R.M.6
  • 80
    • 75149169811 scopus 로고    scopus 로고
    • Natural killer T cells are involved in adipose tissues inflammation and glucose intolerance in diet-induced obese mice
    • Ohmura K., Ishimori N., Ohmura Y., Tokuhara S., Nozawa A., Horii S., et al. Natural killer T cells are involved in adipose tissues inflammation and glucose intolerance in diet-induced obese mice. Arterioscler Thromb Vasc Biol 2010, 30:193-199.
    • (2010) Arterioscler Thromb Vasc Biol , vol.30 , pp. 193-199
    • Ohmura, K.1    Ishimori, N.2    Ohmura, Y.3    Tokuhara, S.4    Nozawa, A.5    Horii, S.6
  • 82
    • 65649117802 scopus 로고    scopus 로고
    • Unexpected trafficking of immune cells within the adipose tissue during the onset of obesity
    • Duffaut C., Galitzky J., Lafontan M., Bouloumie A. Unexpected trafficking of immune cells within the adipose tissue during the onset of obesity. Biochem Biophys Res Commun 2009, 384:482-485.
    • (2009) Biochem Biophys Res Commun , vol.384 , pp. 482-485
    • Duffaut, C.1    Galitzky, J.2    Lafontan, M.3    Bouloumie, A.4
  • 83
    • 85027938385 scopus 로고    scopus 로고
    • B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies
    • Winer D.A., Winer S., Shen L., Wadia P.P., Yantha J., Paltser G., et al. B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies. Nat Med 2011, 17:610-617.
    • (2011) Nat Med , vol.17 , pp. 610-617
    • Winer, D.A.1    Winer, S.2    Shen, L.3    Wadia, P.P.4    Yantha, J.5    Paltser, G.6
  • 84
    • 33746750046 scopus 로고    scopus 로고
    • Antibiotic treatment partially protects against type 1 diabetes in the Bio-Breeding diabetes-prone rat. Is the gut flora involved in the development of type 1 diabetes?
    • Brugman S., Klatter F.A., Visser J.T., Wildeboer-Veloo A.C., Harmsen H.J., Rozing J., et al. Antibiotic treatment partially protects against type 1 diabetes in the Bio-Breeding diabetes-prone rat. Is the gut flora involved in the development of type 1 diabetes?. Diabetologia 2006, 49:2105-2108.
    • (2006) Diabetologia , vol.49 , pp. 2105-2108
    • Brugman, S.1    Klatter, F.A.2    Visser, J.T.3    Wildeboer-Veloo, A.C.4    Harmsen, H.J.5    Rozing, J.6
  • 85
    • 54549122338 scopus 로고    scopus 로고
    • " Innate immunity and intestinal microbiota in the development of Type 1 diabetes"
    • Wen L., Ley R., et al. " Innate immunity and intestinal microbiota in the development of Type 1 diabetes" Nature 2008, 455(7216):1109-1113.
    • (2008) Nature , vol.455 , Issue.7216 , pp. 1109-1113
    • Wen, L.1    Ley, R.2
  • 86
    • 77953302950 scopus 로고    scopus 로고
    • Inflammatory tendencies and overproduction of IL-17 in the colon of young NOD mice are counteracted with diet change
    • Alam C., Valkonen S., Palagani V., Jalava J., Eerola E., Hanninen A. Inflammatory tendencies and overproduction of IL-17 in the colon of young NOD mice are counteracted with diet change. Diabetes 2010, 59:2237-2246.
    • (2010) Diabetes , vol.59 , pp. 2237-2246
    • Alam, C.1    Valkonen, S.2    Palagani, V.3    Jalava, J.4    Eerola, E.5    Hanninen, A.6
  • 87
    • 0041820123 scopus 로고    scopus 로고
    • Immunologic activity in the small intestinal mucosa of pediatric patients with type 1 diabetes
    • Westerholm-Ormio M., Vaarala O., Pihkala P., Ilonen J., Savilahti E. Immunologic activity in the small intestinal mucosa of pediatric patients with type 1 diabetes. Diabetes 2003, 52:2287-2295.
    • (2003) Diabetes , vol.52 , pp. 2287-2295
    • Westerholm-Ormio, M.1    Vaarala, O.2    Pihkala, P.3    Ilonen, J.4    Savilahti, E.5
  • 88
    • 80052829380 scopus 로고    scopus 로고
    • Defective differentiation of regulatory FoxP3+ T cells by small-intestinal dendritic cells in patients with type 1 diabetes
    • Badami E., Sorini C., Coccia M., Usuelli V., Molteni L., Bolla A.M., et al. Defective differentiation of regulatory FoxP3+ T cells by small-intestinal dendritic cells in patients with type 1 diabetes. Diabetes 2011, 60:2120-2124.
    • (2011) Diabetes , vol.60 , pp. 2120-2124
    • Badami, E.1    Sorini, C.2    Coccia, M.3    Usuelli, V.4    Molteni, L.5    Bolla, A.M.6
  • 89
    • 0031114247 scopus 로고    scopus 로고
    • Analysis of intestinal lymphocytes in mouse colitis mediated by transfer of CD4+, CD45RBhigh T cells to SCID recipients
    • Aranda R., Sydora B.C., McAllister P.L., Binder S.W., Yang H.Y., Targan S.R., et al. Analysis of intestinal lymphocytes in mouse colitis mediated by transfer of CD4+, CD45RBhigh T cells to SCID recipients. J Immunol 1997, 158:3464-3473.
    • (1997) J Immunol , vol.158 , pp. 3464-3473
    • Aranda, R.1    Sydora, B.C.2    McAllister, P.L.3    Binder, S.W.4    Yang, H.Y.5    Targan, S.R.6
  • 90
    • 77957236209 scopus 로고    scopus 로고
    • The immune system and the gut microbiota: friends or foes?
    • Cerf-Bensussan N., Gaboriau-Routhiau V. The immune system and the gut microbiota: friends or foes?. Nat Rev Immunol 2010, 10:735-744.
    • (2010) Nat Rev Immunol , vol.10 , pp. 735-744
    • Cerf-Bensussan, N.1    Gaboriau-Routhiau, V.2
  • 91
    • 39549120660 scopus 로고    scopus 로고
    • Microbe sampling by mucosal dendritic cells is a discrete, MyD88-independent step in DeltainvG S. Typhimurium colitis
    • Hapfelmeier S., Muller A.J., Stecher B., Kaiser P., Barthel M., Endt K., et al. Microbe sampling by mucosal dendritic cells is a discrete, MyD88-independent step in DeltainvG S. Typhimurium colitis. J Exp Med 2008, 205:437-450.
    • (2008) J Exp Med , vol.205 , pp. 437-450
    • Hapfelmeier, S.1    Muller, A.J.2    Stecher, B.3    Kaiser, P.4    Barthel, M.5    Endt, K.6
  • 92
    • 77955634800 scopus 로고    scopus 로고
    • Activation of beta-catenin in dendritic cells regulates immunity versus tolerance in the intestine
    • Manicassamy S., Reizis B., Ravindran R., Nakaya H., Salazar-Gonzalez R.M., Wang Y.C., et al. Activation of beta-catenin in dendritic cells regulates immunity versus tolerance in the intestine. Science 2010, 329:849-853.
    • (2010) Science , vol.329 , pp. 849-853
    • Manicassamy, S.1    Reizis, B.2    Ravindran, R.3    Nakaya, H.4    Salazar-Gonzalez, R.M.5    Wang, Y.C.6
  • 93
    • 77951934151 scopus 로고    scopus 로고
    • E-cadherin marks a subset of inflammatory dendritic cells that promote T cell-mediated colitis
    • Siddiqui K.R., Laffont S., Powrie F. E-cadherin marks a subset of inflammatory dendritic cells that promote T cell-mediated colitis. Immunity 2010, 32:557-567.
    • (2010) Immunity , vol.32 , pp. 557-567
    • Siddiqui, K.R.1    Laffont, S.2    Powrie, F.3
  • 94
    • 0035500862 scopus 로고    scopus 로고
    • Lipopolysaccharides from distinct pathogens induce different classes of immune responses in vivo
    • Pulendran B., Kumar P., Cutler C.W., Mohamadzadeh M., Van Dyke T., Banchereau J. Lipopolysaccharides from distinct pathogens induce different classes of immune responses in vivo. J Immunol 2001, 167:5067-5076.
    • (2001) J Immunol , vol.167 , pp. 5067-5076
    • Pulendran, B.1    Kumar, P.2    Cutler, C.W.3    Mohamadzadeh, M.4    Van Dyke, T.5    Banchereau, J.6
  • 95
    • 79955128232 scopus 로고    scopus 로고
    • Dose-dependent immunomodulation of human dendritic cells by the probiotic Lactobacillus rhamnosus Lcr35
    • Evrard B., Coudeyras S., Dosgilbert A., Charbonnel N., Alame J., Tridon A., et al. Dose-dependent immunomodulation of human dendritic cells by the probiotic Lactobacillus rhamnosus Lcr35. PLoS One 2011, 6:e18735.
    • (2011) PLoS One , vol.6
    • Evrard, B.1    Coudeyras, S.2    Dosgilbert, A.3    Charbonnel, N.4    Alame, J.5    Tridon, A.6
  • 97
    • 27744510768 scopus 로고    scopus 로고
    • Dendritic cells in germ-free and specific pathogen-free mice have similar phenotypes and in vitro antigen presenting function
    • Walton K.L., He J., Kelsall B.L., Sartor R.B., Fisher N.C. Dendritic cells in germ-free and specific pathogen-free mice have similar phenotypes and in vitro antigen presenting function. Immunol Lett 2006, 102:16-24.
    • (2006) Immunol Lett , vol.102 , pp. 16-24
    • Walton, K.L.1    He, J.2    Kelsall, B.L.3    Sartor, R.B.4    Fisher, N.C.5
  • 98
    • 12244297799 scopus 로고    scopus 로고
    • CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance
    • Niess J.H., Brand S., Gu X., Landsman L., Jung S., McCormick B.A., et al. CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance. Science 2005, 307:254-258.
    • (2005) Science , vol.307 , pp. 254-258
    • Niess, J.H.1    Brand, S.2    Gu, X.3    Landsman, L.4    Jung, S.5    McCormick, B.A.6
  • 99
    • 77957880664 scopus 로고    scopus 로고
    • High-fat diet: bacteria interactions promote intestinal inflammation which precedes and correlates with obesity and insulin resistance in mouse
    • Ding S., Chi M.M., Scull B.P., Rigby R., Schwerbrock N.M., Magness S., et al. High-fat diet: bacteria interactions promote intestinal inflammation which precedes and correlates with obesity and insulin resistance in mouse. PLoS One 2010, 5:e12191.
    • (2010) PLoS One , vol.5
    • Ding, S.1    Chi, M.M.2    Scull, B.P.3    Rigby, R.4    Schwerbrock, N.M.5    Magness, S.6
  • 100
    • 82455171885 scopus 로고    scopus 로고
    • " Involvement of tissue bacteria in the onset of diabetes in humans: evidence for a concept"
    • Amar J., Serino M., et al. " Involvement of tissue bacteria in the onset of diabetes in humans: evidence for a concept" Diabetologia 2011, 54(12):3055-3061.
    • (2011) Diabetologia , vol.54 , Issue.12 , pp. 3055-3061
    • Amar, J.1    Serino, M.2


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