Lipopolysaccharides from distinct pathogens induce different classes of immune responses in vivo

Journal of Immunology

Volumn 167, Issue 9, 2001, Pages 5067-5076

  Pulendran, B ^a   Kumar, P ^a   Cutler, C W ^a   Mohamadzadeh, M ^a   Van Dyke, T ^a   Banchereau, J ^a  

^a SANOFI   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 3; INTERLEUKIN 4; INTERLEUKIN 5; LIPOPOLYSACCHARIDE; TOLL LIKE RECEPTOR 4;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN SPECIFICITY; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXIC T LYMPHOCYTE; ESCHERICHIA COLI; IMMUNE RESPONSE; IMMUNE SYSTEM; IMMUNITY; MOUSE; NONHUMAN; PORPHYROMONAS GINGIVALIS; PRIORITY JOURNAL; SPLEEN CELL; TH1 CELL;

EID: 0035500862     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.167.9.5067     Document Type: Article

References (62)

1. Immunology: Improving on nature in the twenty-first century
2. TH1 and TH2 cells: Different patterns of lymphokine secretion lead to different functional properties
3. + T cells
4. + T cell responses: The alternative approaches
5. Single cell analyses of cytokine production
6. Cytokines induce the development of functionally heterogeneous T helper cell subsets
7. Signaling and transcription in T helper development
8. Dendritic cell regulation of TH1-TH2 development
9. Modulating the immune response with dendritic cells and their growth factors
10. - subclasses of dendritic cells direct the development of distinct T helper cells in vivo
11. Distinct dendritic cell subsets differentially regulate the class of immune response in vivo
12. Reciprocal control of T helper cell and dendritic cell differentiation
13. The linkage between T-cell and dendritic cell development in the mouse thymus
14. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
15. Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4)
16. - T cells
17. A natural immunological adjuvant enhances T cell clonal expansion through a CD28-dependent, interleukin (IL)-2-independent mechanism
18. Mitogenic activity of lipopolysaccharide from Bacteroides intermedius against C3H/HeJ mice spleen cells
19. Stimulation of splenocytes in C3H/HeJ mice with Porphyromonas gingivalis lipid A in comparison with enterobacterial lipid A
20. Immunopharmacological activities of the nontoxic monophosphoryl lipid A of Porphyromonas gingivalis
21. Splenic B-cell activation in lipopolysaccharide-non-responsive C3H/HeJ mice by lipopolysaccharide of Porphyromonas gingivalis
22. The lipid A moiety of Porphyromonas gingivalis lipopolysaccharide specifically mediates the activation of C3H/HeJ mice
23. Immunobiological activities of chemically defined lipid A from lipopolysaccharides of Porphyromonas gingivalis
24. Immunobiological properties of chemically defined lipid A from lipopolysaccharide of Porphyromonas (Bacteroides) gingivalis
25. Signaling by Toll-like receptor 2 and 4 agonists results in differential gene expression in murine macrophages
26. Immunoglobulin bearing lymphocytes and plasma cells in human periodontal disease
27. Identification and distribution of immunocompetent cells in inflamed gingiva of human chronic periodontitis
28. Molecular and cellular mechanisms for periodontal diseases: Role of Th1 and Th2 type cytokines in induction of mucosal inflammation
29. Clinical benefits of oral irrigation for periodontitis are related to reduction of pro-inflammatory cytokine levels and plaque
30. How the immune system works to protect the host from infection: A personal view
31. Innate immune induction of the adaptive immune response
32. Innate immune recognition: Mechanisms and pathways
33. Toll-like receptors in the induction of the innate immune response
34. The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens
35. Differential roles of TLR2 and TLR4 in recognition of Gram-negative and Gram-positive bacterial cell wall components
36. A Toll like receptor recognizes bacterial DNA
37. The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5
38. The CD14 ligands lipoarabinomannan and lipopolysaccharide differ in their requirement for Toll-like receptors
39. Cutting edge: Recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2
40. Hemin-induced modifications of the antigenicity and hemin-binding capacity of Porphyromonas gingivalis lipopolysaccharide
41. Bacterial lipopolysaccharides: Extraction with phenol water and further applications of the procedure
42. Defective TCR expression in transgenic mice constructed using cDNA-based α- and β-chain genes under the control of heterologous regulatory elements
43. + T cells in vivo is dependent on CD28 costimulation and inhibited by CTLA-4
44. Prevention of peripheral tolerance by a dendritic cell growth factor: Flt3 ligand as an adjuvant
45. T cell receptor antagonist peptides induce positive selection
46. Antigen-specific and nonspecific deletion of immature cortical thymocytes caused by antigen injection
47. Analysis of adjuvant function by direct visualization of antigen presentation in vivo: Endotoxin promotes accumulation of antigen-bearing dendritic cells in the T cell areas of lymphoid tissue
48. Immunological adjuvants and their modes of action
49. Fully mobilizing host defense: Building better vaccines
50. Developmental pathways of dendritic cells in vivo: Distinct function, phenotype, and localization of dendritic cell subsets in FLT3 ligand-treated mice
51. In vivo microbial stimulation induces rapid CD40 ligand-independent production of interleukin 12 by dendritic cells and their redistribution to T cell areas
52. + lymphoid dendritic cells
53. Regulation of dendritic cell numbers and maturation by lipopolysaccharide in vivo
54. Interleukin-12 is required for interferon-γ production and lethality in lipopolysaccharide-induced shock in mice
55. IL-12-deficient mice are defective in IFNγ production and type I cytokine responses
56. T-cell priming by type-1 and type-2 polarized dendritic cells: The concept of a third signal
57. Dynamics of T lymphocyte responses: Intermediates, effectors, and memory cells
58. Sensing pathogens and tuning immune responses
59. Dendritic cells discriminate between yeasts and hyphae of the fungus Candida albicans: Implications for initiation of T helper cell immunity in vitro and in vivo
60. Natural interferon-α/β-producing cells link innate and adaptive immunity
61. Development of Th1-inducing capacity in myeloid dendritic cells requires environmental instruction
62. Maturation, activation, and protection of dendritic cells induced by double-stranded RNA