Leukotriene B4

International Journal of Biochemistry and Cell Biology

Volumn 30, Issue 2, 1998, Pages 173-178

  Crooks, S W ^a   Stockley, R A ^a  

^a QUEEN ELIZABETH HOSPITAL   (United Kingdom)

Author keywords

Inflammation; Leukotriene B4; Neutrophil

Indexed keywords

ARACHIDONATE 5 LIPOXYGENASE; ARACHIDONIC ACID; COMPLEMENT; CYTOKINE; ENDOTOXIN; LEUKOTRIENE A4 HYDROLASE; LEUKOTRIENE B4; TUMOR NECROSIS FACTOR;

CYTOKINE PRODUCTION; DISEASE ACTIVITY; EOSINOPHIL; HUMAN; INFLAMMATION; LEUKOCYTE ACTIVATION; MONOCYTE; NONHUMAN; PATHOGENESIS; REVIEW; TISSUE INJURY;

EID: 0032571150     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1357-2725(97)00123-4     Document Type: Article

References (17)

1. Borgeat P., Samuelsson B. Transformation of arachidonic acid by rabbit polymorphonuclear leukocytes. J. Biol. Chem. 254:1979;2643-2646.
2. Casale T.B., Abbas M.K., Carolan E.J. Degree of neutrophil chemotaxis is dependent upon the chemoattractant and barrier. Am. J. Respir. Cell. Mol. Biol. 7:1992;112-117.
3. Chen X.-S., Sheller J.R., Johnson E.N., Funk C.D. Role of leukotrienes revealed by targeted disruption of the 5-lipoxygenase gene. Nature. 372:1994;179-182.
4. Crooks S.W., Bayley D.L., Llewellyn-Jones C.G., Hill S.L., Stockley R.A. Leukotriene B4 in sputum in chronic bronchitis. Eur. Resp. J. 9:1996;446S.
5. Devchand P.R., Keller H., Peters J.M., Vasquez M., Gonzalez F.J., Wahli W. The PPAR α-leukotriene B4 pathway to inflammation control, Nature. 384:1996;39-43.
6. Evans D.J., Barnes P.J., Spaethe S.M., van Alstyne E.L., Mitchell M.I., O'Connor B.J. Effect of a leukotriene B4 receptor antagonist, LY293111, on allergen induced responses in asthma. Thorax. 51:1996;1178-1184.
7. Fletcher M.P. Modulation of the heterogeneous membrane potential response of neutrophils to N-formyl-methionyl-leucyl-phenylalanine (FMLP) by leukotriene B4: Evidence for cell recruitment. J. Immunol. 136:1986;4213-4219.
8. Ford-Hutchinson A.W., Bray M.A., Doig M.V., Shipley M.E., Smith M.J.H. Leukotriene B4, a potent chemokinetic and aggregating substance released from polymorphonuclear leukocytes. Nature. 286:1980;264-265.
9. Griffiths R.J., Pettipher E.R., Koch K., Farrell C.A., Breslow R., Conklyn M.J., Smith M.A., Hackman B.C., Wimberley D.J., Milici A.J., Scampoli D.N., Cheng J.B., Pillar J.S., Pazoles C.J., Doherty N.S., Melvin L.S., Reiter L.A., Biggars M.S., Falkner F.C., Mitchell D.Y., Liston T.E., Showell H.J. Leukotriene B4 plays a critical role in the progression of collagen-induced arthritis. Proc. Natl. Acad. Sci. USA. 92:1995;517-521.
10. Henderson W.R. Jr. The role of leukotrienes in inflammation. Ann. Int. Med. 121:1994;684-697.
11. Laursen L.S., Lauritsen K., Bukhave K., Raskmadsen J., Jacobsen O., Naesdal J., Goebell H., Peskar B., Rubin P.D., Swanson L.J., Kesterson J.W., Keshavarzian A., Kozarek R., Hanauer S., Cort D., Stenson W.F. Selective 5-lipoxyenase inhibition by zileuton in the treatment of relapsing ulcerative-colitis: A randomised placebo-controlled multicenter trial. Eur. J. Gastroenterol. Hepatol. 6:1994;209-215.
12. Lawrence R., Sorrell T. Eicosapentaenoic acid in cystic fibrosis: evidence of a pathogenetic role for leukotriene B4. Lancet. 342:1993;465-469.
13. Mancini J.A., Abramovitz M., Cox M.E., Wong E., Charleson S., Perrier H., Wang Z., Prasit P., Vickers P.J. Five lipoxygenase activating is an arachidonate binding protein. FEBS Lett. 318:1993;277-281.
14. Samuelsson B., Funk C.D. Enzymes involved in the biosynthesis of leukotriene B4. J. Biol. Chem. 264:1989;19469-19472.
15. Sutbeyaz Y., Yakan B., Ozdemir H., Karasen M., Doner F., Kufrevioglu I. Effect of SC-41930, a potent selective leukotriene B4 receptor antagonist in the guinea pig model of middle ear inflammation. Ann. Otol. Rhinol. Laryngol. 105:1996;476-480.
16. VanderMeer T.J., Menconi M.J., O'Sullivan B.P., Larkin V.A., Wang H.L., Sofia M., Fink M.P. Acute lung injury in endotoxaemic pigs: Role of leukotriene B4. J. Appl. Physiol. 78:1995;1121-1131.
17. Yokomizo T., Izumi T., Chang K., Takuwa Y., Shimizu T. A G-protein-coupled receptor for leuko triene B4 that mediates chemotaxis. Nature. 387:1997;620-624.