Cooperative role of tumour necrosis factor-α, interleukin-1β and neutrophils in a novel behavioural model that concomitantly demonstrates articular inflammation and hypernociception in mice

British Journal of Pharmacology

Volumn 162, Issue 1, 2011, Pages 72-83

  Sachs, Daniela ^a   Coelho, Fernanda M ^a   Costa, Vívian V ^a   Lopes, Fernando ^a   Pinho, Vanessa ^a   Amaral, Flávio A ^a   Silva, Tarcília A ^a   Teixeira, Antônio L ^a   Souza, Daniele G ^a   Teixeira, Mauro M ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

Author keywords

arthritis; chemokine; cytokine; hypernociception; inflammatory pain; neutrophil migration

Indexed keywords

ANTIGEN; CXCL1 CHEMOKINE; DEXAMETHASONE; FUCOIDIN; INFLIXIMAB; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; MORPHINE; MYELOPEROXIDASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTHRALGIA; ARTHRITIS; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOSE RESPONSE; DRUG DOSAGE FORM COMPARISON; DRUG EFFICACY; ENZYME ACTIVITY; HYPERALGESIA; LEUKOCYTE MIGRATION INHIBITION; MALE; MOUSE; NEUTROPHIL CHEMOTAXIS; NEUTROPHIL COUNT; NONHUMAN; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN FUNCTION;

ANIMALS; ARTHRITIS, EXPERIMENTAL; BEHAVIOR, ANIMAL; DEXAMETHASONE; HYPERALGESIA; INTERLEUKIN-1BETA; MICE; MORPHINE; NEUTROPHILS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 78650125232     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2010.00895.x     Document Type: Article

References (46)

1. Alexander SPH, Mathie A, Peters JA, (2009). Guide to Receptors and Channels (GRAC), 4th edn. Br J Pharmacol 158 (Suppl. 1): S1-S254.
2. Barsante MM, Cunha TM, Allegretti M, Cattani F, Policani F, Bizzarri C, et al. (2007). Blockade of the chemokine receptor CXCR2 ameliorates adjuvant-induced arthritis in rats. Br J Pharmacol 153: 992-1002.
3. Butler SH, Godefroy F, Besson JM, Weil-Fugazza J, (1992). A limited arthritic model for chronic pain studies in the rat. Pain 48: 73-81.
4. Chillingworth NL, Donaldson LF, (2003). Characterizations of Freund's complete adjuvant-induced model of chronic arthritis in mice. J Neurosci Methods 128: 45-52.
5. Coelho FM, Pinho V, Amaral FA, Sachs D, Costa V, Rodrigues D, et al. (2008). The chemokine receptors CXCR1/2 modulate antigen-induced arthritis by regulating adhesion of neutrophils to the synovial microvasculature. Arthritis Rheum 58: 1329-2337.
6. Cook CD, Nickerson MD, (2005). Nociceptive sensitivity and opioid antinociception and antihyperalgesia in Freund's adjuvant-induced arthritic male and female rats. J Pharmacol Exp Ther 313: 449-459.
7. Cunha TM, Verri WA Jr, Vivancos GG, Moreira IF, Reis S, Parada CA, et al. (2004). An electronic pressure-meter nociception paw test for mice. Brazil J Med Biol Res 37: 401-407.
8. Cunha TM, Verri WA Jr, Silva JS, Poole S, Cuha FQ, Ferreira SH, (2005). A cascade of cytokines mediates mechanical inflammatory hypernociception in mice. Proc Natl Acad Sci U S A 102: 1755-1760.
9. Cunha TM, Verri WA Jr, Schivo IR, Napimoga MH, Parada CA, Poole S, (2008). Crucial role of neutrophils in the development of mechanical inflammatory hypernociception. J Leukoc Biol 83: 824-832.
10. Ferreira SH, (1972). Prostaglandins, aspirin-like drugs and analgesia. Nat New Biol 240: 200-203.
11. Firestein GS, (2003). Evolving concepts of rheumatoid arthritis. Nature 423: 356-361.
12. Firestein GS, (2005). Immunologic mechanisms in the pathogenesis of rheumatoid arthritis. J Clin Rheumatol 11: S39-S44.
13. 4- dependent recruitment of neutrophils to inflamed joints in mice with antigen-induced arthritis. Arthritis Rheum 58: 2030-20450.
14. Guerrero AT, Verri WA Jr, Cunha TM, Silva TA, Rocha FA, Ferreira SH, et al. (2006). Hypernociception elicited by tibio-tarsal joint flexion in mice: a novel experimental arthritis model for pharmacological screening. Pharmacol Bioch Behav 84: 244-251.
15. Hickey MJ, Reinhardt PH, Ostrovsky L, Jones WM, Jutila MA, Payne D, et al. (1997). Tumor necrosis factor-alpha induces leukocyte recruitment by different mechanisms in vivo and in vitro. J Immunol 158: 3391-3400.
16. Jiang Y, Genant HK, Watt I, Cobby M, Bresnihan B, Aitchison R, et al. (2000). A multicenter, double-blind, dose-ranging, randomized, placebo-controlled study of recombinant human interleukin-1 receptor antagonist in patients with rheumatoid arthritis: radiologic progression and correlation of Genant and Larsen scores. Arthritis Rheum 43: 1001-1009.
17. Kelly M, Hwang JM, Kubes P, (2007). Modulating leukocyte recruitment in inflammation. J Allergy Clin Immunol 120: 3-10.
18. Kitsis E, Weissmann G, (1991). The role of the neutrophil in rheumatoid arthritis. Clin Orthop Relat Res 265: 63-72.
19. Kubes P, Jutila M, Payne D, (1995). Therapeutic potential of inhibiting leukocyte rolling in ischemia/reperfusion. J Clin Invest 95: 2510-2519.
20. Lavich TR, Siqueira Rde A, Farias-Filho FA, Cordeiro RS, Rodrigues e Silva PM, Martins MA, (2006). Neutrophil infiltration is implicated in the sustained thermal hyperalgesic response evoked by allergen provocation in actively sensitized rats. Pain 125: 180-187.
21. Lemos HP, Grespan R, Vieira SM, Cunha TM, Verri WA Jr, Fernandes KSS, et al. (2009). Prostaglandin mediate IL-23/IL-17-induced neutrophils migration in inflammation by inhibiting IL-12 INFγ production. Proc Natl Acad Sci U S A 106: 5954-5959.
22. Levine JD, Lau W, Kwiat G, Goetzl EJ, (1984). Leukotriene B4 produces hyperalgesia that is dependent on polymorphonuclear leukocytes. Science 225: 743-745.
23. Ley K, Linnemann G, Meinen M, Stoolman LM, Gaehtgens P, (1993). Fucoidin, but not yeast polyphosphomannan PPME, inhibits leukocyte rolling in venules of the rat mesentery. Blood 81: 177-185.
24. Liew FY, McInnes IB, (2005). A fork in the pathway to inflammation and arthritis. Nat Med 11: 601-602.
25. Maldonado R, Valverde O, Turcaud S, Fournie-Zaluski MC, Roques BP, (1994). Antinociceptive response induced by mixed inhibitors of enkephalin catabolism in peripheral inflammation. Pain 58: 77-83.
26. Millan MJ, (1999). The induction of pain: an integrative review. Prog Neurobiol 57: 1-164.
27. Moreland LW, Baumgartner SW, Schiff MH, Tindall EA, Fleischmann RM, Weaver AL, et al. (1997). Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein. N Engl J Med 337: 141-147.
28. Nagakura Y, Okada M, Kohara A, Kiso T, Toya T, Iwai A, et al. (2003). Allodynia and hyperalgesia in adjuvant-induced arthritic rats: time course of progression and efficacy of analgesics. J Pharmacol Exp Ther 306: 490-497.
29. Olsen NJ, Stein CM, (2004). New drugs for rheumatoid arthritis. N Engl J Med 350: 2167-2179.
30. Parada CA, Vivancos GG, Tambeli CH, Cunha FQ, Ferreira SH, (2003). Activation of presynaptic NMDA receptors coupled to NaV1.8-resistant sodium channel C-fibers causes retrograde mechanical nociceptor sensitization. Proc Natl Acad Sci U S A 100: 2923-2928.
31. + channel pathway. Proc Natl Acad Sci U S A 101: 3680-3685.
32. Schiff MH, (2000). Role of interleukin 1 and interleukin 1 receptor antagonist in the mediation of rheumatoid arthritis. Ann Rheum Dis 59 (Suppl. I): i103-i108.
33. Scott DL, Kingsley GH, (2006). Tumor necrosis factor inhibitors for rheumatoid arthritis. N Engl J Med 355: 704-712.
34. Shimaoka M, Ikeda M, Iida T, Taenaka N, Yoshiya I, Honda T, (1996). Fucoidin, a potent inhibitor of leukocyte rolling, prevents neutrophil influx into phorbol-ester-induced inflammatory sites in rabbit lungs. Am J Respir Crit Care Med 153: 307-311.
35. Souza DG, Cara DC, Cassali GD, Coutinho SF, Silveira MR, Andrade SP, et al. (2000a). Effects of the PAF receptor antagonist UK74505 on local and remote reperfusion injuries following ischemia of the superior mesenteric artery in the rat. Br J Pharmacol 131: 1800-1808.
36. Souza DG, Coutinho SF, Silveira MR, Cara DC, Teixeira MM, (2000b). Effects of a BLT receptor antagonist on local and remote reperfusion injuries after transient ischemia of the superior mesenteric artery in rats. Eur J Pharmacol 403: 121-128.
37. Souza DG, Cassali GD, Poole S, Teixeira MM, (2001). Effects of inhibition of PDE4 and TNF-alpha on local and remote injuries following ischaemia and reperfusion injury. Br J Pharmacol 134: 985-994.
38. Souza DG, Pinho V, Cassali GD, Poole S, Teixeira MM, (2002a). Effect of a BLT receptor antagonist in a model of severe ischemia and reperfusion injury in the rat. Eur J Pharmacol 440: 61-69.
39. Souza DG, Soares AC, Pinho V, Torloni H, Reis LF, Teixeira MM, et al. (2002b). Increased mortality and inflammation in tumor necrosis factor-stimulated gene-14 transgenic mice after ischemia and reperfusion injury. Am J Pathol 160: 1755-1765.
40. Souza DG, Bertini R, Vieira AT, Cunha FQ, Poole S, Allegretti M, et al. (2004). Repertaxin, a novel inhibitor of rat CXCR2 function, inhibits inflammatory responses that follow intestinal ischaemia and reperfusion injury. Br J Pharmacol 143: 132-142.
41. Teixeira MM, Hellewell PG, (1997). The effect of the selectin binding polysaccharide fucoidin on eosinophil recruitment in vivo. Br J Pharmacol 120: 1059-1066.
42. Teixeira MM, Talvani A, Tafuri WL, Lukacs NW, Hellewell PG, (2001). Eosinophil recruitment into sites of delayed-type hypersensitivity reactions in mice. J Leukoc Biol 69: 353-360.
43. Verri WA Jr, Schivo IR, Cunha TM, Liew FY, Ferreira SH, Cunha FQ, (2004). Interleukin-18 induces mechanical hypernociception in rats via endothelin acting on ETB receptors in a morphine-sensitive manner. J Pharmacol Exp Ther 310: 710-717.
44. Verri WA Jr, Molina RO, Schivo IR, Cunha TM, Parada CA, Poole S, et al. (2005). Nociceptive effect of subcutaneously injected interleukin-12 is mediated by endothelin acting on ETB receptors in rats. J Pharmacol Exp Ther 315: 609-615.
45. Verri JWA, Cunha TM, Parada CA, Poole S, Cunha FQ, Ferreira SH, (2006). Hypernociceptive role of cytokines and chemokines: targets for analgesic drug development? Pharmacol Ther 112: 116-138.
46. Wipke BT, Allen PM, (2001). Essential role of neutrophils in the initiation and progression of a murine model of rheumatoid arthritis. J Immunol 167: 1601-1608.